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Alison Patricia Toth

Associate Professor of Orthopaedic Surgery
Orthopaedic Surgery
Box 3970 Med Ctr, Durham, NC
Duke Sports Sciences Institute, 3475 Erwin Rd, Durham, NC 27710

Selected Publications


Early clinical and patient-reported outcomes for arthroscopic and mini-open superior capsular reconstruction are similar for irreparable rotator cuff tears.

Journal Article J ISAKOS · October 2023 OBJECTIVES: The purpose of this study was to report and compare postoperative range of motion (ROM), patient-reported outcomes, and failure rates following superior capsular reconstruction (SCR) and to compare outcomes between arthroscopic and mini-open te ... Full text Link to item Cite

Microdrilling Resulted in Less Subchondral Bone Destruction Than a Traditional Microfracture Awl for Articular Cartilage Defect Bone Marrow Stimulation.

Journal Article Arthrosc Sports Med Rehabil · October 2023 PURPOSE: The purpose of this study was to compare bone marrow stimulation using micro-computed tomography (micro-CT) analysis of an abrasion arthroplasty technique, drilling k-wire technique, traditional microfacture awl, or a microdrill instrument for sub ... Full text Open Access Link to item Cite

Editorial Commentary: Postoperative Pain Management After Anterior Cruciate Ligament Reconstruction Can Minimize Opioid Use and Allow Early Rehabilitation.

Journal Article Arthroscopy · May 2023 Effective analgesia is essential after anterior cruciate ligament (ACL) reconstruction to control pain while minimizing opioid consumption and allowing early rehabilitation. Orthopaedic surgeons write the third-largest number of opioid prescriptions, which ... Full text Link to item Cite

Altered lower extremity biomechanics following anterior cruciate ligament reconstruction during single-leg and double-leg stop-jump tasks: A bilateral total support moment analysis.

Journal Article Clin Biomech (Bristol, Avon) · January 2022 BACKGROUND: Injury to the anterior cruciate ligament (ACL) can lead to long-lasting biomechanical alterations that put individuals at risk of a second ACL injury. Examining the total support moment may reveal between- and within-limb compensatory strategie ... Full text Link to item Cite

Females have Lower Knee Strength and Vertical Ground Reaction Forces During Landing than Males Following Anterior Cruciate Ligament Reconstruction at the Time of Return to Sport.

Journal Article Int J Sports Phys Ther · 2022 PURPOSE: There is a high rate of second anterior cruciate ligament (ACL) injury (ipsilateral graft or contralateral ACL) upon return-to-sport (RTS) following ACL reconstruction (ACLR). While a significant amount of epidemiological data exists demonstrating ... Open Access Link to item Cite

Isometric Knee Strength is Greater in Individuals Who Score Higher on Psychological Readiness to Return to Sport After Primary Anterior Cruciate Ligament Reconstruction.

Journal Article Int J Sports Phys Ther · 2022 BACKGROUND: Anterior cruciate ligament (ACL) injury is extremely common among athletes. Rate of second ACL injury due to surgical graft rupture or contralateral limb ACL injury is approximately 15-32%. Psychological readiness to return to sport (RTS) may b ... Full text Open Access Link to item Cite

Operative Versus Nonoperative Management of Displaced Midshaft Clavicle Fractures: A Cost-effectiveness Analysis.

Journal Article Orthopedics · 2022 To date, the optimal management of displaced midshaft clavicle fractures remains unknown. Operatively, plate or nail fixation may be used. Nonoperatively, the options are sling or harness. Given the equivocal effectiveness between approaches, the costs to ... Full text Link to item Cite

Consensus on Rehabilitation Guidelines among Orthopedic Surgeons in the United States following Use of Third-Generation Articular Cartilage Repair (MACI) for Treatment of Knee Cartilage Lesions.

Journal Article Cartilage · December 2021 OBJECTIVE: The aim of this study was to evaluate levels of consensus in rehabilitation practices following MACI (autologous cultured chondrocytes on porcine collagen membrane) treatment based on the experience of an expert panel of U.S. orthopedic surgeons ... Full text Link to item Cite

Histologic Analysis of Porcine Dermal Graft Augmentation in Treatment of Rotator Cuff Tears.

Journal Article Am J Sports Med · November 2021 BACKGROUND: Biologic augmentation via extracellular matrix (ECM) scaffolds has been utilized to address rotator cuff tears with poor-quality tissue. PURPOSE: To evaluate the cellular changes in graft explants taken from patients treated with porcine dermal ... Full text Link to item Cite

Immune cell profiles in synovial fluid after anterior cruciate ligament and meniscus injuries.

Journal Article Arthritis research & therapy · November 2021 BackgroundAnterior cruciate ligament (ACL) and meniscus tears are common knee injuries. Despite the high rate of post-traumatic osteoarthritis (PTOA) following these injuries, the contributing factors remain unclear. In this study, we characterize ... Full text Open Access Cite

Group Shear Wave Speed Viscoelastic Analysis using 3D Rotational Volumetric Shear Wave Imaging in Relaxed and Contracted in vivo Muscle

Conference IEEE International Ultrasonics Symposium, IUS · January 1, 2021 To characterize muscle tissue as a viscoelastic transversely isotropic material, we use rotational volumetric shear wave elasticity imaging (SWEI) and group speed viscoelastic analysis. We performed these measurements in vivo in the vastus lateralis of two ... Full text Cite

Factors Affecting in vivo SH and SV Mode Wave Propagation in vastus lateralis Muscle at Varying Knee Flexion Angles Using Ultrasonic Rotational 3D SWEI

Conference IEEE International Ultrasonics Symposium, IUS · January 1, 2021 We previously have demonstrated the use of ultrasonic rotational 3D SWEI to measure all three mechanical properties necessary to fully characterize the vastus lateralis muscle in vivo as an incompressible transversely isotropic material: transverse shear m ... Full text Cite

Risk Factors Associated With Infection in Open Fractures of the Upper and Lower Extremities.

Journal Article J Am Acad Orthop Surg Glob Res Rev · December 8, 2020 INTRODUCTION: Open fractures are associated with a high risk of infection. The prevention of infection is the single most important goal, influencing perioperative care of patients with open fractures. Using data from 2,500 participants with open fracture ... Full text Link to item Cite

Contracture and transient receptor potential channel upregulation in the anterior glenohumeral joint capsule of patients with end-stage osteoarthritis.

Journal Article J Shoulder Elbow Surg · July 2020 BACKGROUND: During anatomic total shoulder arthroplasty (TSA) for primary glenohumeral osteoarthritis (GHOA), the anterior shoulder joint capsule (ASJC) is characterized grossly by contracture, synovitis, and fibrosis. In tissues that develop fibrosis, the ... Full text Link to item Cite

The Female Basketball Player

Chapter · May 1, 2020 Cite

Popliteal Artery Entrapment Syndrome.

Journal Article JBJS Rev · January 2020 » Popliteal artery entrapment syndrome is a commonly misdiagnosed condition that should be considered in patients presenting with exertional lower-extremity pain. » In addition to a focused physical examination, the ankle-brachial index and advanced imagin ... Full text Link to item Cite

Cartilage Surgery in the Juvenile

Chapter · January 1, 2020 Cartilage injuries pose a challenging problem for the surgeon. This is especially true in the skeletally immature patient. Given the skeletal size of a juvenile patient, a seemingly small cartilage injury may represent a proportionally large area, respecti ... Full text Cite

Rotator Cuff Matrix Augmentation and Interposition: A Systematic Review and Meta-analysis.

Journal Article Am J Sports Med · May 2019 BACKGROUND: Surgical management of rotator cuff tears is controversial and complex, ranging from nonoperative management to reverse shoulder arthroplasty. PURPOSE: To systematically review and evaluate the outcomes of graft augmentation or interposition ve ... Full text Link to item Cite

Graft use in the treatment of large and massive rotator cuff tears: an overview of techniques and modes of failure with MRI correlation.

Journal Article Skeletal Radiol · January 2019 Despite technical advances, repair of large or massive rotator cuff tears continues to demonstrate a relatively high rate of failure. Rotator cuff repair or superior capsular reconstruction (SCR) using a variety of commercially available grafts provides a ... Full text Link to item Cite

Early clinical and patient-reported outcomes for arthroscopic and mini-open superior capsular reconstruction are similar for irreparable rotator cuff tears.

Journal Article J ISAKOS · October 2023 OBJECTIVES: The purpose of this study was to report and compare postoperative range of motion (ROM), patient-reported outcomes, and failure rates following superior capsular reconstruction (SCR) and to compare outcomes between arthroscopic and mini-open te ... Full text Link to item Cite

Microdrilling Resulted in Less Subchondral Bone Destruction Than a Traditional Microfracture Awl for Articular Cartilage Defect Bone Marrow Stimulation.

Journal Article Arthrosc Sports Med Rehabil · October 2023 PURPOSE: The purpose of this study was to compare bone marrow stimulation using micro-computed tomography (micro-CT) analysis of an abrasion arthroplasty technique, drilling k-wire technique, traditional microfacture awl, or a microdrill instrument for sub ... Full text Open Access Link to item Cite

Editorial Commentary: Postoperative Pain Management After Anterior Cruciate Ligament Reconstruction Can Minimize Opioid Use and Allow Early Rehabilitation.

Journal Article Arthroscopy · May 2023 Effective analgesia is essential after anterior cruciate ligament (ACL) reconstruction to control pain while minimizing opioid consumption and allowing early rehabilitation. Orthopaedic surgeons write the third-largest number of opioid prescriptions, which ... Full text Link to item Cite

Altered lower extremity biomechanics following anterior cruciate ligament reconstruction during single-leg and double-leg stop-jump tasks: A bilateral total support moment analysis.

Journal Article Clin Biomech (Bristol, Avon) · January 2022 BACKGROUND: Injury to the anterior cruciate ligament (ACL) can lead to long-lasting biomechanical alterations that put individuals at risk of a second ACL injury. Examining the total support moment may reveal between- and within-limb compensatory strategie ... Full text Link to item Cite

Females have Lower Knee Strength and Vertical Ground Reaction Forces During Landing than Males Following Anterior Cruciate Ligament Reconstruction at the Time of Return to Sport.

Journal Article Int J Sports Phys Ther · 2022 PURPOSE: There is a high rate of second anterior cruciate ligament (ACL) injury (ipsilateral graft or contralateral ACL) upon return-to-sport (RTS) following ACL reconstruction (ACLR). While a significant amount of epidemiological data exists demonstrating ... Open Access Link to item Cite

Isometric Knee Strength is Greater in Individuals Who Score Higher on Psychological Readiness to Return to Sport After Primary Anterior Cruciate Ligament Reconstruction.

Journal Article Int J Sports Phys Ther · 2022 BACKGROUND: Anterior cruciate ligament (ACL) injury is extremely common among athletes. Rate of second ACL injury due to surgical graft rupture or contralateral limb ACL injury is approximately 15-32%. Psychological readiness to return to sport (RTS) may b ... Full text Open Access Link to item Cite

Operative Versus Nonoperative Management of Displaced Midshaft Clavicle Fractures: A Cost-effectiveness Analysis.

Journal Article Orthopedics · 2022 To date, the optimal management of displaced midshaft clavicle fractures remains unknown. Operatively, plate or nail fixation may be used. Nonoperatively, the options are sling or harness. Given the equivocal effectiveness between approaches, the costs to ... Full text Link to item Cite

Consensus on Rehabilitation Guidelines among Orthopedic Surgeons in the United States following Use of Third-Generation Articular Cartilage Repair (MACI) for Treatment of Knee Cartilage Lesions.

Journal Article Cartilage · December 2021 OBJECTIVE: The aim of this study was to evaluate levels of consensus in rehabilitation practices following MACI (autologous cultured chondrocytes on porcine collagen membrane) treatment based on the experience of an expert panel of U.S. orthopedic surgeons ... Full text Link to item Cite

Histologic Analysis of Porcine Dermal Graft Augmentation in Treatment of Rotator Cuff Tears.

Journal Article Am J Sports Med · November 2021 BACKGROUND: Biologic augmentation via extracellular matrix (ECM) scaffolds has been utilized to address rotator cuff tears with poor-quality tissue. PURPOSE: To evaluate the cellular changes in graft explants taken from patients treated with porcine dermal ... Full text Link to item Cite

Immune cell profiles in synovial fluid after anterior cruciate ligament and meniscus injuries.

Journal Article Arthritis research & therapy · November 2021 BackgroundAnterior cruciate ligament (ACL) and meniscus tears are common knee injuries. Despite the high rate of post-traumatic osteoarthritis (PTOA) following these injuries, the contributing factors remain unclear. In this study, we characterize ... Full text Open Access Cite

Group Shear Wave Speed Viscoelastic Analysis using 3D Rotational Volumetric Shear Wave Imaging in Relaxed and Contracted in vivo Muscle

Conference IEEE International Ultrasonics Symposium, IUS · January 1, 2021 To characterize muscle tissue as a viscoelastic transversely isotropic material, we use rotational volumetric shear wave elasticity imaging (SWEI) and group speed viscoelastic analysis. We performed these measurements in vivo in the vastus lateralis of two ... Full text Cite

Factors Affecting in vivo SH and SV Mode Wave Propagation in vastus lateralis Muscle at Varying Knee Flexion Angles Using Ultrasonic Rotational 3D SWEI

Conference IEEE International Ultrasonics Symposium, IUS · January 1, 2021 We previously have demonstrated the use of ultrasonic rotational 3D SWEI to measure all three mechanical properties necessary to fully characterize the vastus lateralis muscle in vivo as an incompressible transversely isotropic material: transverse shear m ... Full text Cite

Risk Factors Associated With Infection in Open Fractures of the Upper and Lower Extremities.

Journal Article J Am Acad Orthop Surg Glob Res Rev · December 8, 2020 INTRODUCTION: Open fractures are associated with a high risk of infection. The prevention of infection is the single most important goal, influencing perioperative care of patients with open fractures. Using data from 2,500 participants with open fracture ... Full text Link to item Cite

Contracture and transient receptor potential channel upregulation in the anterior glenohumeral joint capsule of patients with end-stage osteoarthritis.

Journal Article J Shoulder Elbow Surg · July 2020 BACKGROUND: During anatomic total shoulder arthroplasty (TSA) for primary glenohumeral osteoarthritis (GHOA), the anterior shoulder joint capsule (ASJC) is characterized grossly by contracture, synovitis, and fibrosis. In tissues that develop fibrosis, the ... Full text Link to item Cite

The Female Basketball Player

Chapter · May 1, 2020 Cite

Popliteal Artery Entrapment Syndrome.

Journal Article JBJS Rev · January 2020 » Popliteal artery entrapment syndrome is a commonly misdiagnosed condition that should be considered in patients presenting with exertional lower-extremity pain. » In addition to a focused physical examination, the ankle-brachial index and advanced imagin ... Full text Link to item Cite

Cartilage Surgery in the Juvenile

Chapter · January 1, 2020 Cartilage injuries pose a challenging problem for the surgeon. This is especially true in the skeletally immature patient. Given the skeletal size of a juvenile patient, a seemingly small cartilage injury may represent a proportionally large area, respecti ... Full text Cite

Rotator Cuff Matrix Augmentation and Interposition: A Systematic Review and Meta-analysis.

Journal Article Am J Sports Med · May 2019 BACKGROUND: Surgical management of rotator cuff tears is controversial and complex, ranging from nonoperative management to reverse shoulder arthroplasty. PURPOSE: To systematically review and evaluate the outcomes of graft augmentation or interposition ve ... Full text Link to item Cite

Graft use in the treatment of large and massive rotator cuff tears: an overview of techniques and modes of failure with MRI correlation.

Journal Article Skeletal Radiol · January 2019 Despite technical advances, repair of large or massive rotator cuff tears continues to demonstrate a relatively high rate of failure. Rotator cuff repair or superior capsular reconstruction (SCR) using a variety of commercially available grafts provides a ... Full text Link to item Cite

Advanced Patellar Tendinopathy Is Associated With Increased Rates of Bone-Patellar Tendon-Bone Autograft Failure at Early Follow-up After Anterior Cruciate Ligament Reconstruction.

Journal Article Orthop J Sports Med · November 2018 BACKGROUND: Revision anterior cruciate ligament (ACL) reconstruction can be potentially devastating for a patient. As such, it is important to identify prognostic factors that place patients at an increased risk for graft failure. There are no data on the ... Full text Link to item Cite

How to Use a Graft in Irreparable Rotator Cuff Tears: A Literature Review Update of Interposition and Superior Capsule Reconstruction Techniques.

Journal Article Curr Rev Musculoskelet Med · March 2018 PURPOSE OF REVIEW: To introduce the challenges in addressing irreparable rotator cuff tears and examine the surgical options, specifically interposition grafting and superior capsule reconstruction. RECENT FINDINGS: Interposition grafting of rotator cuff t ... Full text Link to item Cite

Posterolateral portal tibial tunnel drilling for posterior cruciate ligament reconstruction: technique and evaluation of safety and tunnel position.

Journal Article Knee Surg Sports Traumatol Arthrosc · August 2017 PURPOSE: To evaluate the safety for neurovascular structures and accuracy for tunnel placement of the posterolateral portal tibial tunnel drilling technique in posterior cruciate ligament (PCL) reconstruction. METHODS: Fifteen fresh-frozen human cadaveric ... Full text Link to item Cite

Interposition Dermal Matrix Xenografts: A Successful Alternative to Traditional Treatment of Massive Rotator Cuff Tears.

Journal Article Am J Sports Med · May 2017 BACKGROUND: Management of massive rotator cuff tears in shoulders without glenohumeral arthritis remains problematic for surgeons. Repairs of massive rotator cuff tears have failure rates of 20% to 94% at 1 to 2 years postoperatively as demonstrated with a ... Full text Link to item Cite

A prospective, multicenter study to evaluate clinical and radiographic outcomes in primary rotator cuff repair reinforced with a xenograft dermal matrix.

Journal Article J Shoulder Elbow Surg · December 2016 BACKGROUND: Minimal information is currently available on the outcome of rotator cuff repair reinforced with an extracellular matrix (ECM) graft. Therefore, the purpose of this study was to determine the clinical and radiographic outcome of repair of large ... Full text Link to item Cite

Inside-Out or Outside-In Suturing Should Not Be Considered the Standard Repair Method for Radial Tears of the Midbody of the Lateral Meniscus: A Systematic Review and Meta-Analysis of Biomechanical Studies.

Journal Article J Knee Surg · October 2016 The purpose was to evaluate which meniscal repair technique for radial tears of the midbody of the lateral meniscus demonstrates the best biomechanical properties. An electronic literature search was conducted using PubMed, EMBASE, CINAHL, and ScienceDirec ... Full text Link to item Cite

Rotator cuff reconstruction and augmentation using polymer, allograft, and xenograft constructs

Journal Article Techniques in Orthopaedics · January 1, 2016 Rotator cuff pathology is an increasingly common diagnosis as the overall population ages and has the potential to cause significant disability due to loss of function and pain. Patients who have rotator cuff tears that classically have been considered "ma ... Full text Cite

Inside-Out Antegrade Tibial Tunnel Drilling Through the Posterolateral Portal Using a Flexible Reamer in Posterior Cruciate Ligament Reconstruction.

Journal Article Arthrosc Tech · October 2015 Posterior cruciate ligament (PCL) reconstruction using the transtibial drilling or arthroscopic tibial-inlay technique has a risk of injury to the popliteal neurovascular bundle because a pin is drilled anterior to posterior. Intraoperative fluoroscopy is ... Full text Link to item Cite

Knee Kinematics During Noncontact Anterior Cruciate Ligament Injury as Determined From Bone Bruise Location.

Journal Article Am J Sports Med · October 2015 BACKGROUND: The motions causing noncontact anterior cruciate ligament (ACL) injury remain unclear. Tibiofemoral bone bruises are believed to be the result of joint impact near the time of ACL rupture. The locations and frequencies of these bone bruises hav ... Full text Link to item Cite

Functional Testing Differences in Anterior Cruciate Ligament Reconstruction Patients Released Versus Not Released to Return to Sport.

Journal Article Am J Sports Med · July 2015 BACKGROUND: No standardized return-to-activity or sport guidelines currently exist after anterior cruciate ligament (ACL) reconstruction. Isokinetic testing and unilateral hop testing, which have construct validity, are often used to make the determination ... Full text Link to item Cite

Stem cell therapies for knee cartilage repair: the current status of preclinical and clinical studies.

Journal Article Am J Sports Med · September 2014 BACKGROUND: Articular cartilage damage of the knee is common, causing significant morbidity worldwide. Many adult tissues contain cells that are able to differentiate into multiple cell types, including chondrocytes. These stem cells have gained significan ... Full text Link to item Cite

Massive or 2-tendon rotator cuff tears in active patients with minimal glenohumeral arthritis: clinical and radiographic outcomes of reconstruction using dermal tissue matrix xenograft.

Journal Article Am J Sports Med · April 2013 BACKGROUND: The management of irreparable massive or full-thickness 2-tendon rotator cuff tears in active patients with minimal glenohumeral arthritis remains a difficult challenge for the treating surgeon. Many different treatment options, with varied suc ... Full text Link to item Cite

Anteromedial subtalar dislocation.

Journal Article BMJ Case Rep · January 25, 2013 Subtalar dislocation is the simultaneous dislocation of the talocalcaneal and talonavicular joints of the foot, typically caused by falls from heights, twisting leg injuries and motor vehicle accidents. The dislocation can occur medially, lateral, anterior ... Full text Link to item Cite

ACL graft failure location differs between allografts and autografts

Journal Article Sports Medicine, Arthroscopy, Rehabilitation, Therapy and Technology · June 14, 2012 Background: Between 5 and 20% of patients undergoing ACL reconstruction fail and require revision. Animal studies have demonstrated slower incorporation of allograft tissue, which may affect the mechanism of graft failure. The purpose of this study is to d ... Full text Cite

Graft size and patient age are predictors of early revision after anterior cruciate ligament reconstruction with hamstring autograft.

Journal Article Arthroscopy · April 2012 PURPOSE: To evaluate whether decreased hamstring autograft size and decreased patient age are predictors of early graft revision. METHODS: Of 338 consecutive patients undergoing primary anterior cruciate ligament (ACL) reconstruction with hamstring autogra ... Full text Link to item Cite

Effects of intraarticular IL1-Ra for acute anterior cruciate ligament knee injury: a randomized controlled pilot trial (NCT00332254).

Journal Article Osteoarthritis Cartilage · April 2012 OBJECTIVE: To evaluate the clinical effectiveness of intraarticular IL-1 receptor antagonist (IL-1Ra) for anterior cruciate ligament (ACL) tear. METHODS: Eleven patients with acute ACL tear confirmed by magnetic resonance imaging (MRI) were randomized to r ... Full text Link to item Cite

Reconstruction of massive irreparable rotator cuff tears with dermal xenograft

Journal Article Techniques in Shoulder and Elbow Surgery · March 1, 2012 The management of massive rotator cuff tears in healthy active patients without evidence of glenohumeral arthritis can present a treatment challenge. Mixed results have been reported in the literature for different treatment options, including arthroscopic ... Full text Cite

Global metabolic profiling of human osteoarthritic synovium.

Journal Article Osteoarthritis Cartilage · January 2012 Osteoarthritis (OA) is a debilitating disease associated with pain and loss of function in numerous diarthrodial joints of the body. Assessments of the severity and/or progression of OA are commonly based on radiographic stages and pain level, which aren't ... Full text Link to item Cite

Dermal tissue allograft for the repair of massive irreparable rotator cuff tears.

Journal Article Am J Sports Med · January 2012 BACKGROUND: Massive irreparable rotator cuff tears in patients without advanced glenohumeral arthritis can pose a challenge to surgeons. Numerous management strategies have been utilized, and studies have shown varied results with regard to shoulder pain, ... Full text Link to item Cite

Emerging ideas: prevention of posttraumatic arthritis through interleukin-1 and tumor necrosis factor-alpha inhibition.

Journal Article Clin Orthop Relat Res · December 2011 BACKGROUND: Despite surgical and mechanical stabilization of an acutely injured joint through ligament reconstruction, meniscus repair, or labral repair, the risk of posttraumatic arthritis remains high. Joint injury triggers three phases of pathogenic eve ... Full text Link to item Cite

Thermal Shrinkage for Shoulder Instability

Journal Article HSS Journal · July 1, 2011 Thermal capsular shrinkage was popular for the treatment of shoulder instability, despite a paucity of outcomes data in the literature defining the indications for this procedure or supporting its long-term efficacy. The purpose of this study was to perfor ... Full text Cite

Isokinetic strength, endurance, and subjective outcomes after biceps tenotomy versus tenodesis: a postoperative study.

Journal Article Am J Sports Med · April 2011 BACKGROUND: Similar subjective outcomes have been reported for tenotomy or tenodesis of the long head of the biceps. Few studies have reported on postoperative strength and endurance. HYPOTHESIS: Biceps tenodesis results in superior subjective outcomes, st ... Full text Link to item Cite

Clinical benefits of intra-articular anakinra for persistent knee effusion.

Journal Article J Knee Surg · March 2011 Postoperative or postinjury inflammation after knee surgery is a significant clinical challenge. Cytokines, particularly interleukin-1 (IL-1), released by inflammatory cells have been shown to have a role in cartilage homeostasis and tissue repair and fibr ... Full text Link to item Cite

Hamstring graft preparation using a needleless suture loop.

Journal Article J Surg Orthop Adv · 2011 Placement of running, locking stitches during the harvest and preparation of hamstring tendons can be time consuming and requires placement of suture in the most distal and proximal 2 to 3 cm of the tendons. The authors have regularly used a needleless sut ... Link to item Cite

Clinical benefits of intra-articular anakinra for arthrofibrosis.

Journal Article Orthopedics · December 1, 2010 Postoperative inflammation and stiffness, as well as the struggle to achieve full range of motion (ROM), following knee surgery is a significant clinical challenge. Interleukin-1 is a crucial mediator of the inflammatory response and development of patholo ... Full text Link to item Cite

MRI appearance of posterior cruciate ligament tears.

Journal Article AJR Am J Roentgenol · October 2008 OBJECTIVE: There is little in the radiology literature regarding the MRI appearance of a torn posterior cruciate ligament (PCL). The purpose of this study was to describe the MRI appearance of surgically proven PCL tears and to emphasize previously unrepor ... Full text Link to item Cite

Stress fractures and stress reactions of the diaphyseal femur in collegiate athletes: an analysis of 25 cases.

Journal Article Am J Orthop (Belle Mead NJ) · September 2008 In this review of prospectively collected data, representing the largest series of its kind, we identified 25 stress injuries of the diaphyseal femur in 20 athletes at an NCAA (National Collegiate Athletic Association) Division I university. All 20 patient ... Link to item Cite

Meniscus transplantation: current concepts.

Journal Article J Knee Surg · April 2008 Treatment options are limited for young, meniscal-deficient patients with pain. This patient population is not age appropriate for total joint replacement, yet the loss of the meniscus leaves them at significant risk for the development of osteoarthritis. ... Full text Link to item Cite

Free vascularized fibular grafting following failed core decompression for femoral head osteonecrosis.

Journal Article J Arthroplasty · August 2007 The results of treatment of femoral head osteonecrosis with free vascularized fibular grafting (FVFG) following failed core decompression (core decompression-FVFG [CD-FVFG] group: 32 hips) were reviewed and compared with those of a control group that under ... Full text Link to item Cite

Complications of Allograft Use in Anterior Cruciate Ligament Reconstruction

Journal Article Operative Techniques in Sports Medicine · January 1, 2006 Ligament allografts remain a popular option for primary and revision anterior cruciate ligament (ACL) reconstruction. There are several important considerations for surgeons and patients when considering the use of ligament allografts, including disease tr ... Full text Cite

Examination of posterolateral corner injuries.

Journal Article J Knee Surg · April 2005 Physical examination of patients with a suspected posterolateral corner injury must be comprehensive. Mechanical alignment, gait, and any hyperextension or varus thrust should all be evaluated. The status of all ligaments of the knee also must be thoroughl ... Full text Link to item Cite

Medicolegal issues in sports medicine.

Journal Article Clin Orthop Relat Res · April 2005 Featured Publication This article reviews medicolegal issues in sports medicine. Nonmusculoskeletal medical conditions discussed include cardiac abnormalities, heat illness, and concussion in the athlete. Musculoskeletal injuries with the greatest potential for litigation, kne ... Full text Link to item Cite

Examination of posterolateral corner injuries.

Journal Article The journal of knee surgery · 2005 Physical examination of patients with a suspected posterolateral corner injury must be comprehensive. Mechanical alignment, gait, and any hyperextension or varus thrust should all be evaluated. The status of all ligaments of the knee also must be thoroughl ... Cite

Provider Volume of Total Knee Arthroplasties and Patient Outcomes in the HCUP-Nationwide Inpatient Sample.

Journal Article J Bone Joint Surg Am · September 2003 Featured Publication BACKGROUND: The relationship between volume and outcome of total knee arthroplasties has never been evaluated in a nationally representative sample, to our knowledge. We hypothesized that surgeons and hospitals with higher patient volumes would have better ... Full text Link to item Cite

Pelvic stress injuries in the athlete: management and prevention.

Journal Article Sports Med · 2003 Stress-related injuries of the pelvis are an important consideration in sports medicine. Diagnosis of stress injuries may be difficult and requires a high index of suspicion. Plain radiographs are the first step in imaging but magnetic resonance imaging is ... Full text Link to item Cite

Pectoralis Ruptures

Internet Publication · 2002 Cite

Anterior cruciate ligament injuries in the female athlete.

Journal Article J Gend Specif Med · 2001 Featured Publication With the participation of women in athletics growing rapidly over the last two decades, a disturbing gender-specific pre-disposition has emerged regarding anterior cruciate ligament (ACL) injuries of the knee. Female athletes have a two- to eightfold highe ... Link to item Cite

Ankle chondral injuries and repair.

Journal Article Foot Ankle Clin · December 2000 Featured Publication The success of cartilage repair in the ankle and other joints rests on multiple factors. Because native cartilage healing fails to produce hyaline, organized cartilage, the challenge lies in activating an appropriate healing response. The combination of an ... Link to item Cite

Marshall Urist Award. Interstitial collagenase gene expression correlates with in vitro invasion in human chondrosarcoma.

Journal Article Clinical orthopaedics and related research · July 2000 Matrix metalloproteinases contribute to the processes of local invasion and metastasis by providing cells with the ability to traverse tissue boundaries. The levels of gene expression were quantitated for matrix metalloproteinases-1 and tissue inhibitors o ... Cite

Marshall Urist Award. Interstitial collagenase gene expression correlates with in vitro invasion in human chondrosarcoma.

Journal Article Clin Orthop Relat Res · July 2000 Matrix metalloproteinases contribute to the processes of local invasion and metastasis by providing cells with the ability to traverse tissue boundaries. The levels of gene expression were quantitated for matrix metalloproteinases-1 and tissue inhibitors o ... Full text Link to item Cite

Association between ratio of matrix metalloproteinase-1 to tissue inhibitor of metalloproteinase-1 and local recurrence, metastasis, and survival in human chondrosarcoma.

Journal Article J Bone Joint Surg Am · January 1998 Featured Publication Chondrosarcoma, a malignant cartilage-forming mesenchymal tumor, displays a wide range of clinical behavior that can be difficult to predict with histological analysis. Matrix metalloproteinases contribute to the processes of local invasion and metastasis ... Link to item Cite