Tyler Allen
Postdoctoral Associate
Current Appointments & Affiliations
- Postdoctoral Associate, Duke Cancer Institute, Institutes and Centers
Contact Information
- 905 LaSalle Street, 6044 GSRB I, Durham, NC 27704
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tyler.allen@duke.edu
+1 919 681 9608
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Personal Website
- Recognition
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Awards & Honors
- Expertise
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Subject Headings
- Research
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Selected Grants
- Race-related differential RNA splicing: novel targets for precision oncology in non-small cell lung cancer awarded by National Institutes of Health 2020 - 2025
- Race-related germline genetic variation and response to secondary hormonal therapy in metastatic castration-resistant prostate cancer awarded by Department of Defense 2019 - 2023
- Race-related differential RNA splicing: novel targets for precision oncology in non-small cell lung cancer awarded by Department of Defense 2020 - 2022
- Interrogating Race-related Alternative Splicing Variation in Metastasis awarded by American Association for Cancer Research 2020 - 2022
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Fellowships, Supported Research, & Other Grants
- AACR-Genentech Cancer Disparities Research Fellowship awarded by AACR-Genentech 2020 - 2022
- Multicellular Cancer Cell Cluster Extravasation through Angiopellosis awarded by NCI 2017 - 2018
- Publications & Artistic Works
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Selected Publications
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Books
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Freedman, Jennifer A., Muthana Al Abo, Tyler A. Allen, Sean A. Piwarski, Kara Wegermann, and Steven R. Patierno. Biological Aspects of Cancer Health Disparities. Vol. 72, 2021. https://doi.org/10.1146/annurev-med-070119-120305.Full Text Link to Item
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Academic Articles
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Deveaux, April E., Tyler A. Allen, Muthana Al Abo, Xiaodi Qin, Dadong Zhang, Brendon M. Patierno, Lin Gu, et al. “RNA splicing and aggregate gene expression differences in lung squamous cell carcinoma between patients of West African and European ancestry.” Lung Cancer 153 (March 2021): 90–98. https://doi.org/10.1016/j.lungcan.2021.01.015.Full Text Link to Item
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Allen, Tyler A., Mark M. Cullen, Nathan Hawkey, Hiroyuki Mochizuki, Lan Nguyen, Elyse Schechter, Luke Borst, et al. “A Zebrafish Model of Metastatic Colonization Pinpoints Cellular Mechanisms of Circulating Tumor Cell Extravasation.” Front Oncol 11 (2021): 641187. https://doi.org/10.3389/fonc.2021.641187.Full Text Link to Item
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Dinh, Phuong-Uyen C., Dipti Paudel, Hayden Brochu, Kristen D. Popowski, M Cyndell Gracieux, Jhon Cores, Ke Huang, et al. “Inhalation of lung spheroid cell secretome and exosomes promotes lung repair in pulmonary fibrosis.” Nature Communications 11, no. 1 (February 2020): 1064. https://doi.org/10.1038/s41467-020-14344-7.Full Text
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Qiao, Li, Shiqi Hu, Ke Huang, Teng Su, Zhenhua Li, Adam Vandergriff, Jhon Cores, et al. “Tumor cell-derived exosomes home to their cells of origin and can be used as Trojan horses to deliver cancer drugs.” Theranostics 10, no. 8 (2020): 3474–87. https://doi.org/10.7150/thno.39434.Full Text Open Access Copy Link to Item
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Allen, Tyler A., Dana Asad, Emmanuel Amu, M Taylor Hensley, Jhon Cores, Adam Vandergriff, Junnan Tang, et al. “Circulating tumor cells exit circulation while maintaining multicellularity, augmenting metastatic potential.” J Cell Sci 132, no. 17 (September 9, 2019). https://doi.org/10.1242/jcs.231563.Full Text Open Access Copy Link to Item
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Qiao, Li, Shiqi Hu, Suyun Liu, Hui Zhang, Hong Ma, Ke Huang, Zhenhua Li, et al. “microRNA-21-5p dysregulation in exosomes derived from heart failure patients impairs regenerative potential.” J Clin Invest 129, no. 6 (April 29, 2019): 2237–50. https://doi.org/10.1172/JCI123135.Full Text Open Access Copy Link to Item
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Su, Teng, Ke Huang, Hong Ma, Hongxia Liang, Phuong-Uyen Dinh, Justin Chen, Deliang Shen, et al. “Platelet-Inspired Nanocells for Targeted Heart Repair After Ischemia/Reperfusion Injury.” Adv Funct Mater 29, no. 4 (January 24, 2019). https://doi.org/10.1002/adfm.201803567.Full Text Open Access Copy Link to Item
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Su, Teng, Ke Huang, Michael A. Daniele, Michael Taylor Hensley, Ashlyn T. Young, Junnan Tang, Tyler A. Allen, et al. “Cardiac Stem Cell Patch Integrated with Microengineered Blood Vessels Promotes Cardiomyocyte Proliferation and Neovascularization after Acute Myocardial Infarction.” Acs Appl Mater Interfaces 10, no. 39 (October 3, 2018): 33088–96. https://doi.org/10.1021/acsami.8b13571.Full Text Open Access Copy Link to Item
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Liang, Hongxia, Ke Huang, Teng Su, Zhenhua Li, Shiqi Hu, Phuong-Uyen Dinh, Emily A. Wrona, et al. “Mesenchymal Stem Cell/Red Blood Cell-Inspired Nanoparticle Therapy in Mice with Carbon Tetrachloride-Induced Acute Liver Failure.” Acs Nano 12, no. 7 (July 24, 2018): 6536–44. https://doi.org/10.1021/acsnano.8b00553.Full Text Open Access Copy Link to Item
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Tang, Junnan, Teng Su, Ke Huang, Phuong-Uyen Dinh, Zegen Wang, Adam Vandergriff, Michael T. Hensley, et al. “Targeted repair of heart injury by stem cells fused with platelet nanovesicles.” Nat Biomed Eng 2 (2018): 17–26. https://doi.org/10.1038/s41551-017-0182-x.Full Text Open Access Copy Link to Item
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Cores, Jhon, M Taylor Hensley, Kathryn Kinlaw, S Michaela Rikard, Phuong-Uyen Dinh, Dipti Paudel, Junnan Tang, et al. “Safety and Efficacy of Allogeneic Lung Spheroid Cells in a Mismatched Rat Model of Pulmonary Fibrosis.” Stem Cells Translational Medicine 6, no. 10 (October 2017): 1905–16. https://doi.org/10.1002/sctm.16-0374.Full Text
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Dinh, Phuong-Uyen C., Jhon Cores, M Taylor Hensley, Adam C. Vandergriff, Junnan Tang, Tyler A. Allen, Thomas G. Caranasos, Kenneth B. Adler, Leonard J. Lobo, and Ke Cheng. “Derivation of therapeutic lung spheroid cells from minimally invasive transbronchial pulmonary biopsies.” Respiratory Research 18, no. 1 (June 2017): 132. https://doi.org/10.1186/s12931-017-0611-0.Full Text
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Tang, Junnan, Adam Vandergriff, Zegen Wang, Michael Taylor Hensley, Jhon Cores, Tyler A. Allen, Phuong-Uyen Dinh, Jinying Zhang, Thomas George Caranasos, and Ke Cheng. “A Regenerative Cardiac Patch Formed by Spray Painting of Biomaterials onto the Heart.” Tissue Engineering. Part C, Methods 23, no. 3 (March 2017): 146–55. https://doi.org/10.1089/ten.tec.2016.0492.Full Text
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Allen, Tyler A., David Gracieux, Maliha Talib, Debra A. Tokarz, M Taylor Hensley, Jhon Cores, Adam Vandergriff, et al. “Angiopellosis as an Alternative Mechanism of Cell Extravasation.” Stem Cells (Dayton, Ohio) 35, no. 1 (January 2017): 170–80. https://doi.org/10.1002/stem.2451.Full Text
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Tang, Junnan, Deliang Shen, Thomas George Caranasos, Zegen Wang, Adam C. Vandergriff, Tyler A. Allen, Michael Taylor Hensley, et al. “Therapeutic microparticles functionalized with biomimetic cardiac stem cell membranes and secretome.” Nature Communications 8 (January 2017): 13724. https://doi.org/10.1038/ncomms13724.Full Text
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Henry, Eric, Jhon Cores, M Taylor Hensley, Shirena Anthony, Adam Vandergriff, James B. M. de Andrade, Tyler Allen, Thomas G. Caranasos, Leonard J. Lobo, and Ke Cheng. “Adult Lung Spheroid Cells Contain Progenitor Cells and Mediate Regeneration in Rodents With Bleomycin-Induced Pulmonary Fibrosis.” Stem Cells Translational Medicine 4, no. 11 (November 2015): 1265–74. https://doi.org/10.5966/sctm.2015-0062.Full Text
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Andrade, James NBM de, Junnan Tang, Michael Taylor Hensley, Adam Vandergriff, Jhon Cores, Eric Henry, Tyler A. Allen, et al. “Rapid and Efficient Production of Coronary Artery Ligation and Myocardial Infarction in Mice Using Surgical Clips.” Plos One 10, no. 11 (January 2015): e0143221. https://doi.org/10.1371/journal.pone.0143221.Full Text
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Book Sections
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Allen, Tyler A., and Ke Cheng. “Imaging and Isolation of Extravasation-Participating Endothelial and Melanoma Cells During Angiopellosis.,” 2265:417–25, 2021. https://doi.org/10.1007/978-1-0716-1205-7_30.Full Text
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Conference Papers
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Patierno, Brendon M., Wen-Chi Foo, Tyler Allen, Jason A. Somarelli, Kathryn E. Ware, Santosh Gupta, Sandra Wise, et al. “Characterization of a castrate-resistant prostate cancer xenograft derived from a patient of West African ancestry.” In Prostate Cancer Prostatic Dis, 25:513–23, 2022. https://doi.org/10.1038/s41391-021-00460-y.Full Text Open Access Copy Link to Item
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