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Tyler Allen

Research Program Leader, Tier 1
Duke Cancer Institute
Box 103861, 3044 GSRB 1, Durham, NC 27710
905 LaSalle Street, 6044 GSRB I, Durham, NC 27704

Current Appointments & Affiliations


Research Program Leader, Tier 1 Duke Cancer Institute, Institutes and Centers

Recent Publications


The Role of Circulating Tumor Cells as a Liquid Biopsy for Cancer: Advances, Biology, Technical Challenges, and Clinical Relevance

Journal Article Cancers · April 1, 2024 Cancer remains a leading cause of mortality worldwide, with metastasis significantly contributing to its lethality. The metastatic spread of tumor cells, primarily through the bloodstream, underscores the importance of circulating tumor cells (CTCs) in onc ... Full text Cite

Characterization of a castrate-resistant prostate cancer xenograft derived from a patient of West African ancestry.

Conference Prostate Cancer Prostatic Dis · September 2022 BACKGROUND: Prostate cancer is a clinically and molecularly heterogeneous disease, with highest incidence and mortality among men of African ancestry. To date, prostate cancer patient-derived xenograft (PCPDX) models to study this disease have been difficu ... Full text Open Access Link to item Cite

RNA splicing and aggregate gene expression differences in lung squamous cell carcinoma between patients of West African and European ancestry.

Journal Article Lung Cancer · March 2021 OBJECTIVES: Despite disparities in lung cancer incidence and mortality, the molecular landscape of lung cancer in patients of African ancestry remains underexplored, and race-related differences in RNA splicing remain unexplored. MATERIALS AND METHODS: We ... Full text Link to item Cite
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Recent Grants


Race-related differential RNA splicing: novel targets for precision oncology in non-small cell lung cancer

ResearchPostdoctoral Associate · Awarded by Department of Defense · 2020 - 2022

Interrogating Race-related Alternative Splicing Variation in Metastasis

FellowshipPI-Fellow · Awarded by American Association for Cancer Research · 2020 - 2022

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