Overview
Tyler K. Hornsby is a Medical Physicist and Assistant Professor in the Department of Radiation Oncology at Duke University. He received his B.Sc. degree in Physics with a minor in Nanoscience from the University of Calgary (Calgary, AB, Canada) in 2017, followed by his M.Sc. and Ph.D. degrees in Biomedical Physics and CAMPEP Medical Physics from Toronto Metropolitan University (Toronto, ON, Canada) in 2019 and 2023, respectively. From 2023 to 2025, he completed his residency in Radiation Oncology Physics through McGill University stationed at St. Peter’s Hospital in Albany, New York.
He joined Duke in 2025 and works clinically in high dose rate gynecological brachytherapy, low dose rate eye plaque brachytherapy and intraoperative radiation therapy. His research interests include noninvasive ultrasound thermometry, therapeutic ultrasound hyperthermia, high intensity focused ultrasound (HIFU), nanoparticle-based drug delivery systems, targeted chemotherapy and combination therapy.
Current Appointments & Affiliations
Recent Publications
Journal Article
Drug Deliv Transl Res
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September 2024
In the present work, we have designed a one-pot green protocol in which anti-cancer drugs (curcumin and doxorubicin) can be directly loaded on the surface of gold nanoparticles during their formation. We have further demonstrated that low-intensity pulsed ...
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Journal Article
Wiley Interdiscip Rev Nanomed Nanobiotechnol
·
2024
Computational modeling enables researchers to study and understand various complex biological phenomena in anticancer drug delivery systems (DDSs), especially nano-sized DDSs (NSDDSs). The combination of NSDDSs and therapeutic ultrasound (TUS), that is, fo ...
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Journal Article
Sci Rep
·
December 2, 2023
Therapeutic ultrasound can be used to trigger the on-demand release of chemotherapeutic drugs from gold nanoparticles (GNPs). In the previous work, our group achieved doxorubicin (DOX) release from the surface of GNPS under low-intensity pulsed ultrasound ...
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Education, Training & Certifications
Toronto Metropolitan University (Canada) ·
2023
Ph.D.
Toronto Metropolitan University (Canada) ·
2019
M.S.
University of Calgary (Canada) ·
2017
B.S.