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Vadim Y Arshavsky

Helena Rubinstein Foundation Distinguished Professor of Ophthalmology
Ophthalmology, Vitreoretinal Diseases & Surgery
Box 3802 Med Ctr, Durham, NC 27710
Duke Eye Center, 2351 Erwin Rd. Box 3802, 5012 Aeri, Durham, NC 27710

Selected Grants


Investigating Endocytic Mechanisms in Lysosome Rich Enterocytes

ResearchCo Investigator · Awarded by National Institutes of Health · 2024 - 2029

Molecular mechanisms of photoreceptor disc morphogenesis

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2023 - 2028

Role of Proteasome Overload in Pathogenesis of Retinitis Pigmentosa

ResearchMentor · Awarded by National Institutes of Health · 2022 - 2027

Gene-Agnostic Therapy for Retinal Degenerations

ResearchPrincipal Investigator · Awarded by Foundation Fighting Blindness, Inc · 2024 - 2027

Center Core Grant for Vision Research

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2001 - 2026

Cell and Molecular Biology Training Program

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2021 - 2026

Identification of proteins localized to photoreceptor connecting cilium

ResearchCo Investigator · Awarded by National Institutes of Health · 2024 - 2026

Pharmacological Sciences Training Grant

Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 2020 - 2025

Activation of Cellular Proteostasis as an Approach to Treat Inherited Retinal Degenerations

ResearchPrincipal Investigator · Awarded by Foundation Fighting Blindness, Inc · 2022 - 2025

Mechanisms of photoreceptor disc maturation

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2020 - 2025

Elucidating the role of EYS in the pathogenesis of retinitis pigmentosa

ResearchPrincipal Investigator · Awarded by VitreoRetinal Surgery Foundation · 2023 - 2024

The role of ADAM9 in retinal health and disease

ResearchMentor · Awarded by National Institutes of Health · 2022 - 2024

Molecular mechanisms of photoreceptor outer segment morphogenesis

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2005 - 2023

Mechanisms of photoreceptor protein transport and compartmentalization

ResearchPrincipal Investigator · Awarded by SUNY Upstate Medical University · 2021 - 2023

In Vivo Modeling of Mitochondrial Complex I Deficiency in Retinal Ganglion Cells

ResearchMentor · Awarded by National Institutes of Health · 2018 - 2023

Gene therapy treatment of neurodegeneration using proteasome activators

ResearchPrincipal Investigator · Awarded by Sio Gene Therapies · 2021 - 2022

Understanding the roles of ectosomes and the associated microglial response in photoreceptor degeneration

ResearchPrincipal Investigator · Awarded by Knights Templar Eye Foundation, Inc. · 2021 - 2022

Rhodopsin dimerization: mechanistic basis and functional consequences

ResearchPrincipal Investigator · Awarded by Weill Medical College of Cornell University · 2017 - 2022

Pathological and functional consequences of dimerization-deficient rhodopsin mutations

FellowshipPrincipal Investigator · Awarded by National Institutes of Health · 2019 - 2022

Repulsive mechanisms for spatial segregation of developing neural circuits

FellowshipCo-Sponsor · Awarded by National Institutes of Health · 2017 - 2020

Organization and Function of Cellular Structure

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 1975 - 2020

Pharmacological Sciences Training Program

Inst. Training Prgm or CMEParticipating Faculty Member · Awarded by National Institutes of Health · 1975 - 2020

The Role of Basal Bodies in Wnt Signaling

ResearchCollaborator · Awarded by National Institutes of Health · 2007 - 2020

Coherent light scattering for early detection of Alzheimer's disease

ResearchCo Investigator · Awarded by National Institutes of Health · 2017 - 2020

How Do Muller Glia Control Circuit-Specific Retinal Synaptogenesis?

FellowshipCo-Sponsor · Awarded by National Institutes of Health · 2017 - 2019

Understanding the function of PRCD, a small protein whose mutations cause blindness

FellowshipPrincipal Investigator · Awarded by National Institutes of Health · 2016 - 2019

Molecular & cellular cues for circuit assembly in mouse retina

FellowshipCo-Sponsor · Awarded by National Institutes of Health · 2016 - 2019

RPB: 2014 Nelson Trust Award

ResearchPrincipal Investigator · Awarded by Research To Prevent Blindness, Inc. · 2014 - 2019

Developing a new therapeutic agent for retinal ciliopathies

ResearchPrincipal Investigator · Awarded by Rescindo Therapeutics Inc · 2017 - 2019

Identification of unique rod outer segment plasma membrane proteins

ResearchCo Investigator · Awarded by National Institutes of Health · 2017 - 2019

Role of impaired protein degradation in photoreceptor degeneration

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2013 - 2018

Understanding the function of PRCD, a small protein whose mutations cause blindness

FellowshipPrincipal Investigator · Awarded by National Institutes of Health · 2015 - 2018

Understanding Photoreceptor Trafficking Pathways to the Outer Segment

ResearchMentor · Awarded by National Institutes of Health · 2015 - 2017

Modifiers of Retinal Phenotypes in Ciliopathies

ResearchCollaborator · Awarded by National Institutes of Health · 2011 - 2017

P30 - Center Core Grant for Vision Research: Administrative Supplement

EquipmentPrincipal Investigator · Awarded by National Institutes of Health · 1997 - 2016

Coherent light scattering for early detection of retinal disease

ResearchCo Investigator · Awarded by National Institutes of Health · 2013 - 2016

Cellular mechanism of targeting peripherin to the sensory cilium

FellowshipPrincipal Investigator · Awarded by National Institutes of Health · 2012 - 2015

Protein Translocation and Photoreceptor Light Adaptation

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 1994 - 2012

Ankyrin G in protein sorting between rod plasma membrane and photoreceptor discs

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2010 - 2012

Proteome Map of the Photoreceptor Cell

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2006 - 2009

External Relationships


  • Progress in Retinal and Eye Research journal
  • Research to Prevent Blindness

This faculty member (or a member of their immediate family) has reported outside activities with the companies, institutions, or organizations listed above. This information is available to institutional leadership and, when appropriate, management plans are in place to address potential conflicts of interest.