Virginia Byers Kraus | Scholars@Duke

Virginia Byers Kraus
Professor of Medicine

My special area of expertise is as a clinician scientist investigating osteoarthritis. Osteoarthritis is the most common form of joint disease in man and its incidence increases with age. It is a problem of increasing concern to the medical community due to the increasing longevity of the population. Trained as a molecular biologist and a Rheumatologist, I endeavor to study this disease from bedside to bench.

The work in this laboratory focuses on osteoarthritis and deals with the mechanisms of joint damage, and the discovery, validation and qualification of novel biochemical and genetic biomarkers for minimally invasive means of diagnosing disease, for predicting progression of disease, and for monitoring disease progression and response to therapy.

Current Appointments & Affiliations

Professor of Medicine, Medicine, Rheumatology and Immunology, Medicine 2010
Professor of Pathology, Pathology, Clinical Science Departments 2010
Professor in Orthopaedic Surgery, Orthopaedics, Orthopaedics 2015
Member of Duke Molecular Physiology Institute, Duke Molecular Physiology Institute, Duke Molecular Physiology Institute 2013
Affiliate of the Regeneration Next Initiative, Regeneration Next Initiative, Institutes and Centers 2016

Contact Information

300 N Duke St, Carmichael Building Room 15-205, Durham, NC 27701-2047
Duke Box 104775, Durham, NC 27701
kraus004@duke.edu (919) 681-6652

Background
Education, Training, & Certifications
- Ph.D., Duke University 1993
- Fellow In Rheumatology, Medicine, Duke University 1986 - 1989
- Medical Resident, Medicine, Duke University 1983 - 1986
- M.D., Duke University 1982
Duke Appointment History
- Associate Professor in Surgery, Surgery, Clinical Science Departments 2010 - 2015
- Assistant Professor of Pathology, Pathology, Clinical Science Departments 1996 - 2010
- Assistant Professor in Surgery, Surgery, Clinical Science Departments 2000 - 2010
- Associate Professor of Medicine, Medicine, Rheumatology and Immunology, Medicine 2004 - 2010
- Associate Professor of Medicine, Medicine, Rheumatology and Immunology, Medicine 2003 - 2004
- Assistant Professor of Medicine, Medicine, Rheumatology and Immunology, Medicine 1995 - 2003
- Assistant Clinical Professor of Medicine, Medicine, Clinical Science Departments 1991 - 1995
Recognition
Awards & Honors
Research
Selected Grants
- Age-related alterations in the in vivo mechanical function of the spine awarded by National Institutes of Health 2017 - 2020
- Behavioral and Physiology in Aging awarded by National Institutes of Health 2015 - 2020
- Organization and Function of Cellular Structure awarded by National Institutes of Health 1975 - 2020
- Qualification of Prognostic and Diagnostic Biomarkers of Knee Osteoarthritis awarded by National Institutes of Health 2017 - 2020
- Evaluation of Anti-inflammatory effects of naproxen sodium on human osteoarthritis synovial cells awarded by Bayer Corporation 2017 - 2018
- Behavioral Weight and Symptom Management for Breast Cancer Survivors and Partners awarded by National Institutes of Health 2015 - 2018
- An integrated and diverse genomic medicine program for undiagnosed diseases awarded by National Institutes of Health 2014 - 2018
- Training Program in Inflammatory and Immunological Diseases awarded by National Institutes of Health 1980 - 2017
- Leukocyte Gene Expresssion & Genetic Biomarkers of OA Incidence and Progression. awarded by New York University School of Medicine 2012 - 2017
- University Training Program in Biomolecular and Tissue Engineering awarded by National Institutes of Health 1994 - 2017
- Macrophage Model System awarded by Bioiberica, S.A. 2016 - 2017
- Obesity, Biomechanics, and Inflammation in Osteoarthritis awarded by National Institutes of Health 2013 - 2016
- Bioiberica "Pre-Pilot Mobile App for OA" awarded by Bioiberica, S.A. 2014 - 2015
- Behavior And Physiology In Aging awarded by National Institutes of Health 1999 - 2015
- Live-Animal Micro-CT System awarded by National Institutes of Health 2012 - 2014
- Development of Methods to Quantify Biological and Pathological Aging of Cartilage awarded by National Institutes of Health 2011 - 2013
- Function and Behavior Phenotype of Inflammatory Arthritis in the Rat Knee and TMJ awarded by National Institutes of Health 2009 - 2011
- Training in Biomolecular and Tissue Engineering awarded by National Institutes of Health 2003 - 2009
- Determination of OA Pathology by Biomarker Dating awarded by National Institutes of Health 2003 - 2009
- STRATEGIES TO PREDICT OSTEOARTHRITIS PROGRESSION awarded by National Institutes of Health 2002 - 2009
- Biomarkers Network Sample Repository awarded by National Institutes of Health 2003 - 2008
- Chondrocyte Deformation and Mechanical Transduction awarded by National Institutes of Health 1997 - 2003
- Metalloproteinases In Aging And Osteoarthritis awarded by National Institutes of Health 1998 - 2003
- Metalloproteinases in aging and osteoarthritis awarded by National Institutes of Health 1998 - 2003
- Minority Suppl - Metalloproteinases in aging and osteoarthritis awarded by National Institutes of Health 1998 - 2003
- Cartilage Function and Micro-MRI After Meniscal Repair awarded by National Institutes of Health 1997 - 2000
- Intravenous Doxycycline For Rheumatoid Arthritis awarded by National Institutes of Health 1994 - 1998
- Cellular Genes Mediating E1a-Like Transcription Control awarded by National Institutes of Health 1992 - 1993
- Cellular Genes Mediating Ela-Like Transcription Control awarded by National Institutes of Health 1989 - 1993
Publications & Artistic Works
Selected Publications
- Book Reviews
  - Hsueh, M-F, Önnerfjord, P, and Kraus, VB. "Biomarkers and proteomic analysis of osteoarthritis." Matrix biology : journal of the International Society for Matrix Biology 39 (October 2014): 56-66. Full Text Open Access Copy
  - Kraus, VB. "Rare Osteoarthritis: Ochronosis and Kashin-Beck Disease." Rheumatology, 6th edition, Ed. MC Hochberg, AJ Silman, JS Smolen, ME Weinblatt, MH Weisman (Mosby Elsevier, Philadelphia). 2014;Chapter 185:1536-1540. . Open Access Copy
- Book Sections
  - Golightly, YM, Adams, SB, and Kraus, VB. "Biomarkers of PTA." In Post-Traumatic Arthritis: Pathogenesis, Diagnosis and Management, 317-330. January 1, 2015. Full Text Open Access Copy
  - Kraus, VB. "Rare osteoarthritis: Ochronosis and Kashin-Beck disease." In Rheumatology: Sixth Edition, 1536-1547. June 19, 2014. Full Text
  - Kraus, VB. "Preclinical osteoarthritis." In Rheumatology: Sixth Edition, 1498-1502. June 19, 2014. Full Text
  - Kraus, VB. "Preclinical Osteoarthritis." . Open Access Copy
- Conference Papers
  - Attur, M, Ma, S, Samuels, J, Samuels, SK, Zhou, H, Bencardino, JT, Hochberg, MC, Mitchell, BD, Kraus, VB, Jordan, JM, and Abramson, SB. "FUNCTIONAL GENETIC POLYMORPHISM OF IL-1RN ENCODING THE IL-1 RECEPTOR ANTAGONIST PREDICTS RADIOGRAPHIC SEVERITY OF SYMPTOMATIC KNEE OA." April 2017. Link to Item
  - Chou, C-H, Attarian, DE, Wisniewski, H-G, Band, P, and Kraus, VB. "TSG-6-A DOUBLE-EDGED SWORD FOR OSTEOARTHRITIS." April 2017. Link to Item
  - Conaghan, P, Strand, V, Hunter, D, Kraus, VB, Berenbaum, F, Katz, NP, Lufkin, J, Johnson, JR, Kelley, S, and Bodick, N. "AN INTRA-ARTICULAR, EXTENDED RELEASE FORMULATION OF TRIAMCINOLONE (FX006) AFFORDS CLINICALLY RELEVANT IMPROVEMENTS IN PAIN AND FUNCTION OF KNEE OSTEOARTHRITIS: POST-HOC POOLED ANALYSES OF 3 RANDOMIZED CONTROLLED TRIALS." April 2017. Link to Item
  - Flowers, P, Cleveland, RJ, Schwartz, TA, Nelson, AE, Kraus, VB, Hillstrom, HJ, Goode, AP, Hannan, MT, Renner, JB, Jordan, JM, and Golightly, YM. "ASSOCIATION OF JOINT HYPERMOBILITY AND LOWER BODY OSTEOARTHRITIS BY RACE." April 2017. Link to Item
  - Furman, BD, Kimmerling, KA, Ramamoorthy, S, Li, Y-J, Wu, Y-H, Huebner, JL, Guilak, F, Kraus, VB, and Olson, SA. "ARTICULAR FRACTURE UPREGULATES LIPID METABOLITES IN HUMAN SYNOVIAL FLUID." April 2017. Link to Item
  - Goode, AP, Cleveland, RJ, Schwartz, TA, Nelson, AE, Kraus, VB, Hillstrom, HJ, Hannan, MT, Flowers, P, Renner, JB, Jordan, JM, and Golightly, YM. "RELATIONSHIP OF JOINT HYPERMOBILITY WITH LOW BACK PAIN AND LUMBAR SPINE OSTEOARTHRITIS: A POOLED ANALYSIS OF THREE CROSS-SECTIONAL STUDIES." April 2017. Link to Item
  - Haraden, C, Kraus, VB, Attarian, D, Laberge, R-M, and Chou, C-H. "SENESCENCE INDICATORS ARE POSITIVELY ASSOCIATED WITH SEVERITY OF OSTEOARTHRITIS." April 2017. Link to Item
  - Hsueh, M-F, Kraus, VB, and Onnerfjord, P. "QUANTITATIVE ASSESSMENT OF CARTILAGE REMODELING IN HEALTH AND DISEASE." April 2017. Link to Item
  - Hsueh, M-F, Lu, Y, Wheeler, L, Wellman, SS, Bolognesi, MP, and Kraus, VB. "Functional folate receptor cells within synovium and fluid as therapeutic targets for osteoarthritis." April 2017. Full Text
  - Huebner, JL, Furman, BD, Kimmerling, KA, Olson, SA, Guilak, F, and Kraus, VB. "IDENTIFICATION OF BIOMARKERS INDICATIVE OF SYNOVITIS IN THE MOUSE ARTICULAR FRACTURE MODEL OF PTA." April 2017. Link to Item
  - Sr, ME, Sr, STV, Sr, VJ, and Sr, KVB. "CHONDROITIN SULPHATE INHIBITS MONOCYTE CHEMOATTRACTANT PROTEIN-1 RELEASE FROM 3T3L1 ADIPOCYTES: A NEW TREATMENT OPPORTUNITY FOR OBESITY-RELATED METABOLIC SYNDROMES?." April 2017. Link to Item
  - Kraus, VB, Hargrove, DE, Hunter, DJ, Renner, JB, and Jordan, JM. "Establishment of reference intervals for osteoarthritis-related soluble biomarkers: the FNIH/OARSI OA Biomarkers Consortium." January 2017. Full Text
  - Montell, E, Stabler, T, Verges, J, and Kraus, VB. "CHONDROITIN SULPHATE INHIBITION OF NF-kappa B ACTIVITY: ATTENTUATION OF HYALURONAN FRAGMENT INDUCED INFLAMMATORY RESPONSE IN MACROPHAGES BY CHONDROITIN SULPHATE IS MEDIATED BY REDUCTION IN NF-kappa B ACTIVITY." October 2016. Link to Item
  - Golightly, YM, Goode, AP, Cleveland, RJ, Nelson, AE, Hannan, MT, Hillstrom, HJ, Kraus, VB, Schwartz, TA, Renner, JB, and Jordan, JM. "FRI0598 Relationship of Joint Hypermobility with Low Back Pain and Lumbar Spine Osteoarthritis: A Cohort Study." June 2016. Full Text
  - Golightly, YM, Nelson, AE, Hannan, MT, Hillstrom, HJ, Kraus, VB, Cleveland, RJ, Goode, AP, Schwartz, TA, Renner, JB, and Jordan, JM. "SAT0614 Joint Hypermobility and Ankle Osteoarthritis in A Community-Based Cohort." June 2016. Full Text
  - Stabler, T, Montell, E, Vergés, J, and Kraus, VB. "FRI0037 Chondroitin Sulphate Inhibition of NF-κB Activity: Attentuation of Hyaluronan Fragment Induced Inflammatory Response in Macrophages by Chondroitin Sulphate Is Mediated by Reduction in NF-κB Activity." June 2016. Full Text
  - Chou, C-H, Wisniewski, H-G, Band, P, Huebner, J, Stabler, T, Lattermann, C, and Kraus, VB. "TSG-6 ACTIVITY REFLECTS SEVERITY OF INFLAMMATION IN KNEE OSTEOARTHRITIS AND ACUTE JOINT INJURY." April 2016. Link to Item
  - Grasso, MA, Yesha, Y, Rishe, N, Kraus, VB, and Niskar, A. "A BIG DATA APPROACH FOR SELECTION OF A LARGE OSTEOARTHRITIS COHORT." April 2016. Link to Item
  - Kraus, VB, Catterall, J, Soderblom, E, Moseley, MA, and Suchindran, S. "DEVELOPMENT OF A SERUM BIOMARICER PANEL HIGHLY PREDICTIVE OF KNEE OSTEOARTHRITIS PROGRESSION." April 2016. Link to Item
  - Kraus, VB, Catterall, J, Soderblom, E, Moseley, MA, and Suchindran, S. "DEVELOPMENT OF A SERUM BIOMARICER PANEL HIGHLY PREDICTIVE OF A KNEE OSTEOARTHRITIS DIAGNOSIS." April 2016. Link to Item
  - Kraus, VB, Martinez, H, Herrero, M, and Verges, J. "A PROTEOMIC PANEL PREDICTS DRUG RESPONSE TO THE COMBINATION OF GLUCOSAMINE AND CHONDROITIN SULFATE." April 2016. Link to Item
  - Leung, YY, Huebner, JL, Wong, B, and Kraus, VB. "ASSOCIATION OF SYNOVIAL FLUID INFLAMMATORY BIOMARICERS AND KNEE PAIN." April 2016. Link to Item
  - Leung, YY, Wong, B, Haaland, B, and Kraus, VB. "ASSOCIATION BETWEEN RADIOGRAPHIC SEVERITY AND PAIN IN KNEE OSTEOARTHRITIS." April 2016. Link to Item
  - Nwosu, LN, Chapman, V, Walsh, DA, and Kraus, VB. "SUBCHONDRAL BONE BIOMARKERS AS PREDICTORS OF OA PAIN PROGRESSION; LINKING STRUCTURAL PATHOLOGY AND PAIN." April 2016. Link to Item
  - Stabler, T, Montell, E, Verges, J, and Kraus, VB. "CHONDROHITIN SULPHATE INHIBITION OF NF-kappa B ACTIVITY: ATTENTUATTON OF HYALURONAN FRAGMENT INDUCED INFLAMMATORY RESPONSE IN MACROPHAGES BY CHONDROITIN SULPHATE IS MEDIATED BY REDUCTION IN NF-kappa B ACTIVITY." April 2016. Link to Item
  - Stabler, T, Zura, RD, Hsueh, M-F, and Kraus, VB. "Xanthine oxidase injurious response in acute joint injury." December 2015. Full Text
  - Montell, E, Stabler, T, Verges, J, and Kraus, VB. "ATTENTUATION OF HYALURONAN FRAGMENT INDUCED INFLAMMATORY RESPONSE IN MACROPHAGES BY CHONDROITIN SULPHATE." August 2015. Link to Item
  - Chou, C-H, Lee, M, Song, I-W, Lu, L-S, Wu, J-Y, Chen, Y-T, Kraus, VB, and Wu, C-C. "INSIGHTS INTO OSTEOARTHRITIS PROGRESSION REVEALED BY ANALYSES OF BOTH KNEE TIBIOFEMORAL COMPARTMENTS." April 2015. Link to Item
  - Daghestani, HN, Huang, Z, and Kraus, VB. "CHARACTERIZATION OF FOLATE RECEPTOR BETA EXPRESSION ON CELLS OF BONE ORIGIN." April 2015. Link to Item
  - Daghestani, HN, Jordan, JM, Doherty, M, Wilson, A, and Kraus, VB. "N-PROPEPTIDE OF COLLAGEN IIA (PIIANP) AS A MARKER OF OSTEOARTHRITIS BURDEN." April 2015. Link to Item
  - Hsueh, M-F, Khabut, A, Kjellstrom, S, Onnerfjord, P, and Kraus, VB. "CARTILAGE PERMEABILITY ASSESSMENT BASED ON PROTEOMIC ANALYSIS OF PLASMA PROTEIN PENETRATION." April 2015. Link to Item
  - Hsueh, M-F, Kraus, VB, Khabut, A, and Onnerfjord, P. "QUANTITATIVE PROTEOMICS OF ARTICULAR CARTILAGE USING SEQUENTIAL EXTRACTION OF TRANSVERSE CRYOSECTIONS." April 2015. Link to Item
  - Stabler, T, Montell, E, Verges, J, and Kraus, VB. "ATTENTUATION OF HYALURONAN FRAGMENT INDUCED INFLAMMATORY RESPONSE IN MACROPHAGES BY CHONDROITIN SULPHATE." April 2015. Link to Item
  - Taylor, AM, Hsueh, M-F, Ranganath, LR, Gallagher, JA, Catterall, JB, and Kraus, VB. "ANALYSIS OF CARTILAGE BIOMARKERS OF AGING AND TURNOVER IN THE OSTEOARTHROPATHY OF ALKAPTONURIA." April 2015. Link to Item
  - Wu, C-L, McNeill, J, Goon, K, Little, D, Kimmerling, K, Huebner, J, Kraus, V, and Guilak, F. "THE EFFECT OF CONDITIONAL MACROPHAGE DEPLETION ON DEVELOPMENT OF INJURY-INDUCED KNEE OA IN OBESE TRANSGENIC MAFIA MICE." April 2015. Link to Item
  - Daghestani, HN, Pieper, CF, and Kraus, VB. "RELEASED MACROPHAGE MARKERS AS PREDICTORS OF KNEE OA PROGRESSION." April 2014. Link to Item
  - Kraus, VB, Pieper, CF, Halaweish, A, Newman, E, Berasi, C, Bolognesi, M, Charles, C, Frobell, R, and Lohmander, LS. "RADIOGRAPHIC SUBCHONDRAL BONE TRABECULAR INTEGRITY PREDICTS OSTEOARTHRITIS STRUCTURAL OUTCOMES AFTER ANTERIOR CRUCIATE LIGAMENT RUPTURE." April 2014. Link to Item
  - Lattermann, C, Proffitt, M, Kraus, VB, and Spindler, KP. "MOON-AAA GCP CLINICAL TRIAL: EARLY LESSONS FROM AN EARLY INTERVENTIONAL TRIAL IN PATIENTS WITHIN 1 WEEK AFTER ACL TEAR." April 2014. Link to Item
  - Goode, AP, Nelson, AE, Kraus, VB, Renner, JB, and Jordan, JM. "Biomarkers Reflect Differences In Osteoarthritis Phenotypes Of The Lumbar Spine: The Johnston County Osteoarthritis Project." October 2013. Link to Item
  - Karsdal, MA, Huebner, JL, Kraus, VB, Leeming, DJ, Coleman, E, McDaniel, GE, Huffman, KM, Henriksen, K, and Bay-jensen, AC. "Subchondral Bone Turnover and Osteophyte Formation Are Key Aspects In The Progression Of Osteoarthritis and May Be Assessed and Predicted By a-CTX." October 2013. Link to Item
  - Orlowsky, EW, Stabler, TV, Montell, E, Verges, J, and Kraus, VB. "Monosodium Urate Crystal Induced Macrophage Inflammation Is Attenuated By Chondroitin Sulfate: Pre-Clinical Model For Gout Prophylaxis?." October 2013. Link to Item
  - Chou, C-H, Lee, C-H, Lu, L-S, Song, I-W, Chuang, H-P, Kuo, S-Y, Wu, J-Y, Chen, Y-T, Kraus, VB, Wu, C-C, and Lee, M-TM. "DIRECT ASSESSMENT OF ARTICULAR CARTILAGE AND UNDERLYING SUBCHONDRAL BONE REVEALS A PROGRESSIVE GENE EXPRESSION CHANGE IN HUMAN OSTEOARTHRITIC KNEES." April 2013. Link to Item
  - Cibere, J, Sayre, EC, Esdaile, JM, Thorne, A, Kopec, JA, Singer, J, Nicolaou, S, Garnero, P, Poole, AR, Kraus, VB, Saxne, T, Wong, H, and Guermazi, A. "ASSOCIATIONS OF CLINICAL AND BIOMARKER VARIABLES WITH CARTILAGE DAMAGE IN PAINFUL PRE-RADIOGRAPHIC KNEE OSTEOARTHRITIS. RESULTS FROM A POPULATION-BASED STUDY." April 2013. Link to Item
  - Daghestani, HN, McDaniel, G, Huebner, JL, Stabler, T, Pieper, C, Coleman, E, and Kraus, VB. "SOLUBLE MACROPHAGE BIOMARKERS ARE ASSOCIATED WITH OSTEOARTHRITIS-RELATED KNEE INFLAMMATION." April 2013. Link to Item
  - Hsueh, M-F, Soderblom, EJ, Zura, RD, Bolognesi, MP, and Kraus, VB. "STUDY OF DEAMIDATION OF CARTILAGE EXTRACELLULAR MATRIX PROTEINS TO INVESTIGATE CARTILAGE TURNOVER." April 2013. Link to Item
  - Kraus, VB, McDaniel, G, Huebner, JL, Stabler, T, Pieper, C, Coleman, RE, Petry, NA, Low, PS, Shen, J, and Mitchell, P. "DIRECT IN VIVO EVIDENCE OF ACTIVATED MACROPHAGES IN HUMAN OSTEOARTHRITIS." April 2013. Link to Item
  - Orlowsky, EW, Stabler, TV, Montell, E, Vergas, J, and Kraus, VB. "THE EFFECTS OF CHONDROITIN SULPHATE ON INFLAMMASOME ACTIVATION." April 2013. Link to Item
  - Wu, C-L, Jain, D, Little, D, Anderson, JA, Huebner, JL, Kraus, VB, Rodriguiz, RM, Wetsel, WC, and Guilak, F. "DIETARY FATTY ACIDS DIFFERENTIALLY AFFECT THE DEVELOPMENT OF INJURY-INDUCED OSTEOARTHRITIS WITH DIET-INDUCED OBESITY IN MICE." April 2013. Link to Item
  - Ning, T, Pieper, C, Kraus, VB, Kraus, WE, and Huffman, KM. "Knee Osteoarthritis and Serum Uric Acid Concentration: The Third National Health and Examination Survey." October 2012. Link to Item
  - Yin, Z-X, Shi, X-M, Kraus, VB, Sereny, MD, Zeng, Y, and Shi, X-M. "HS-CRP AND TRADITIONAL RISK FACTORS: WHO IS STILL SIGNIFICANTLY ASSOCIATED WITH DIABETES IN CHINESE OLDEST-OLD?." October 2012. Full Text Link to Item
  - Aslam, I, Shi, X, Renner, JB, Kraus, VB, Golightly, YM, Nelson, AE, and Jordan, JM. "The Association between Australian/Canadian Hand Osteoarthritis Index (AUSCAN) and Biomarkers of Joint Metabolism." April 2012. Link to Item
  - Golightly, YM, Nelson, AE, Kraus, VB, Renner, JB, and Jordan, JM. "GENERAL JOINT HYPERMOBILITY AND HIP OSTEOARTHRITIS: THE JOHNSTON COUNTY OSTEOARTHRITIS PROJECT." April 2012. Link to Item
  - Goode, AP, Kraus, VB, Marshall, SW, Renner, JB, Carey, TS, and Jordan, JM. "ASSOCIATIONS BETWEEN LUMBAR SPINE INDIVIDUAL RADIOGRAPHIC FEATURES AND KNEE, HIP AND HAND OSTEOARTHRITIS: THE JOHNSTON COUNTY OSTEOARTHRITIS PROJECT." April 2012. Link to Item
  - Huebner, JL, Ha, N, Bourdon, S, and Kraus, VB. "PERFORMANCE METRICS OF A NEWLY FORMATTED TYPE II COLLAGEN CLEAVAGE NEO-EPITOPE ASSAY FOR HUMAN URINE: C2C-HUSA." April 2012. Link to Item
  - Huebner, JL, Landerman, LR, Somers, TJ, Kraus, VB, Guilak, F, Blumenthal, JA, Caldwell, DS, Rice, JR, and Keefe, FJ. "INFLAMMATORY BIOMARKERS OF OA, IL-6 AND LEPTIN ARE MODIFIABLE IN OVERWEIGHT/OBESE OA PATIENTS WITH A PROTOCOL THAT COMBINES TRAINING IN PAIN COPING SKILLS AND WEIGHT MANAGEMENT." April 2012. Link to Item
  - Hunt, MA, Pollock, CL, Kraus, VB, Saxne, T, Peters, S, Huebner, JL, Sayre, EC, and Cibere, J. "BIOMARKERS OF CARTILAGE DEGRADATION AND SYNTHESIS RELEVANT TO KNEE OSTEOARTHRITIS: RELATIONSHIPS WITH DYNAMIC KNEE JOINT LOAD AND CHANGES FOLLOWING EXERCISE." April 2012. Link to Item
  - Nelson, AE, Renner, JB, Golightly, YM, Schwartz, TA, Kraus, VB, Helmick, CG, and Jordan, JM. "DIFFERENCES IN MULTI-JOINT SYMPTOMATIC OSTEOARTHRITIS PHENOTYPES BY RACE AND GENDER: THE JOHNSTON COUNTY OSTEOARTHRITIS PROJECT." April 2012. Link to Item
  - Goode, AP, Kraus, VB, Golightly, YM, Marshall, SW, Irwin, DE, and Jordan, JM. "Association of Lumbar Spine Individual Radiographic Features with Serum C-Propeptide (sCPII) and Serum Collagen Neoepitope (sC2C) of Type II Collagen: The Johnston County Osteoarthritis Project." October 2011. Link to Item
  - Lekpa, FK, Kraus, VB, and Chevalier, X. "Biologics In Relapsing Polychondritis: a Literature Review." October 2011. Link to Item
  - Ning, T, Pieper, C, Kraus, VB, Kraus, WE, and Huffman, KM. "Serum Uric Acid Concentration and Physical Activity: the National Health and Nutrition Examination Survey 2003-2004." October 2011. Link to Item
  - Yau, MS, Yerges-Armstrong, L, Doherty, M, Hochberg, M, Jordan, JM, Kraus, VB, Mitchell, B, Wilson, AG, and Investigators, GOGO. "Heritability and Linkage of Radiographic Progression of Hip and Knee Osteoarthritis: Results From the Longitudinal Component of the Genetics of Generalized Osteoarthritis Study." October 2011. Link to Item
  - Golightly, YM, Marshall, SW, Kraus, VB, Renner, JB, Villaveces, A, Casteel, C, and Jordan, JM. "SERUM CARTILAGE OLIGOMERIC MATRIX PROTEIN, HYALURONAN, HIGH-SENSITIVITY C-REACTIVE PROTEIN, AND KERATAN SULFATE AS PREDICTORS OF INCIDENT RADIOGRAPHIC KNEE OSTEOARTHRITIS: DIFFERENCES BY CHRONIC KNEE SYMPTOMS." October 2010. Link to Item
  - Huebner, JL, Jensen, ACB, Leeming, DJ, Coleman, RE, McDaniel, G, Karsdal, MA, and Kraus, VB. "URINARY MARKERS, ALPHA CTX AND CTXII, ARE INDICATIVE OF OA SEVERITY AND BONE TURNOVER." October 2010. Link to Item
  - Kraus, VB, Birmingham, J, Stabler, T, Feng, S, Taylor, DC, Moorman, CT, Garrett, WE, and Toth, A. "INTRAARTICULAR IL1-RA AFTER ACUTE KNEE INJURY DECREASES BIOMARKERS OF INFLAMMATION AND IMPROVES PAIN AND FUNCTION." October 2010. Link to Item
  - Nelson, AE, DeVellis, RF, Renner, JB, Conaghan, PG, Kraus, VB, and Jordan, JM. "A COMPOSITE SCORE OF MULTI-JOINT RADIOGRAPHIC OSTEOARTHRITIS: THE JOHNSTON COUNTY OSTEOARTHRITIS PROJECT." October 2010. Link to Item
  - Stabler, TV, Heinrichs, AE, Huffman, KM, McDaniel, GE, and Kraus, VB. "INFLAMMASOME ACTIVATION IN OSTEOARTHRITIS BY URIC ACID." October 2010. Link to Item
  - Maksymowych, WP, Fitzgerald, O, Wells, GA, Gladman, DD, Landewe, R, Ostergaard, M, Taylor, WJ, Christensen, R, Tak, P-P, Boers, M, Syversen, SW, Bathon, JM, Ritchlin, CJ, Mease, PJ, Bykerk, VP, Garnero, P, Geusens, P, El-Gabalawy, H, Aletaha, D, Inman, RD, Kraus, VB, Kvien, TK, and van der Heijde, D. "Proposal for Levels of Evidence Schema for Validation of a Soluble Biomarker Reflecting Damage Endpoints in Rheumatoid Arthritis, Psoriatic Arthritis, and Ankylosing Spondylitis, and Recommendations for Study Design." August 2009. Full Text Link to Item
  - Chen, JC, Kraus, VB, Callahan, LF, Stabler, T, Renner, JB, and Jordan, JM. "Higher educational level is associated with decreased serum cartilage oligomeric matrix protein (COMP)." September 2008. Link to Item
  - Nelson, AE, Fang, F, Kraus, VB, Stabler, T, Renner, JB, Helmick, CG, and Jordan, JM. "Is serum transforming growth factor-beta (TGF-beta) a biomarker of radiographic osteoarthritis (rOA) at the knee and hip?." September 2008. Link to Item
  - Birmingham, JD, Kraus, VB, and Toth, AP. "Clinical benefits of intra-articular anakinra (Kineret) for knee signs and symptoms of injury, arthritis, and arthrofibrosis." December 2006. Link to Item
  - Allen, KD, DeVellis, RF, Renner, JB, Kraus, VB, and Jordan, JM. "Validity and factor structure of the AUSCAN osteoarthritis hand index in an African American and white community sample." September 2006. Link to Item
  - McCudden, CR, and Kraus, VB. "Protein racemization as a biomarker of osteoarthritis." June 2006. Link to Item
  - Elliott, AL, Fang, F, Kraus, VB, Renner, JB, Helmick, C, Hochberg, MC, and Jordan, JM. "Association of symptoms and signs of hand osteoarthritis with hip and knee osteoarthritis in African-Americans and Caucasians." September 2005. Link to Item
  - Mazzuca, SA, Kraus, VB, Jordan, JM, Brandt, KD, Katz, BP, Lane, KA, and Elliott, A. "Relationship of baseline cartilage oligomeric matrix protein (COMP) levels to joint space narrowing (JSN) in patients with knee osteoarthritis (OA)." September 2005. Link to Item
  - Dominick, KL, Jordan, JM, Renner, JB, and Kraus, VB. "Relationships of radiographic and clinical variables to pinch and grip strength among patients with osteoarthritis." September 2004. Link to Item
  - Jordan, JM, Kraus, VB, Renner, JB, Luta, G, Dragomir, AD, Ionescu, M, Lobanok, T, King, L, and Poole, AR. "Predictive ability of serum biomarkers of types I and II collagen cleavage and aggrecan turnover in incidence and progression of radiographic knee osteoarthritis in African Americans and Caucasians." September 2004. Link to Item
  - Jordan, JM, Kraus, VB, Renner, JB, Luta, G, Dragomir, AD, Ionescu, M, Lobanok, T, King, L, and Poole, AR. "Ethnic and gender differences in serum biomarkers of types I and II collagen cleavage and aggrecan turnover in African Americans and Caucasians." September 2004. Link to Item
  - McDaniel, GE, Vail, TP, and Kraus, VB. "Comparison of knee alignment angle by x-ray and goniometer." September 2004. Link to Item
  - Dragomir, AD, Jordan, JM, Kraus, VB, Luta, G, Renner, JB, and Poole, AR. "Altered levels of serum cartilage markers in postmenopausal African-American and caucasian women on current hormone replacement therapy." 2004. Link to Item
  - Eckstein, F, Buck, RJ, Charles, HC, Hudelmaier, M, Wirth, W, Kraus, VB, and Evelhoch, JL. "Improved precision of quantitative cartilage measurements with magnetic resonance imaging at 3 T." 2004. Link to Item
  - Kraus, VB. "Using epidemiologic studies to identify surrogates for radiographic outcome." 2004. Link to Item
  - Dragomir, AD, Kraus, VB, Luta, G, Stabler, T, Renner, JB, Helmick, CG, Hochberg, MC, and Jordan, JM. "Lower levels of 2 putative biomarkers of osteoarthritis (OA) in postmenopausal African American and Caucasian women on current hormone replacement therapy." September 2003. Link to Item
  - Jordan, JM, Kraus, VB, Renner, JB, Luta, G, Dragomir, AD, Stabler, T, Vilim, V, Hochberg, MC, and Helmick, CG. "Associations between medical co-morbidities and putative biomarkers of osteoarthritis (OA)." September 2003. Link to Item
  - Stabler, TV, Jordan, JM, Kraus, VB, Luta, G, Renner, JB, Dragomir, AD, Hochberg, MC, and Helmick, CG. "Serum C-reactive protein (CRP) levels and osteoarthritis." June 2003. Link to Item
  - Dragomir, AD, Kraus, VB, Stabler, T, Luta, G, Renner, JB, Arab, L, Hochberg, MC, Helmick, CG, and Jordan, JM. "Lower levels of serum cartilage oligomeric matrix protein (COMP) in postmenopausal African-American and caucasian women on current hormone replacement therapy (HRT)." September 2002. Link to Item
  - Jordan, JM, Luta, G, Stabler, T, Renner, JB, Dragomir, AD, Hochberg, MC, Helmick, CG, and Kraus, VB. "Serum c-reactive protein (CRP) and osteoarthritis (OA)." September 2002. Link to Item
  - Jordan, JM, Luta, G, Stabler, T, Renner, JB, Dragomir, AD, Hochberg, MC, Helmick, CG, and Kraus, VB. "Serum hyaluronic acid levels and radiographic knee Osteoarthritis in African-Americans and caucasians." September 2002. Link to Item
  - Little, D, Wu, CL, Jain, D, McNeill, J, Anderson, J, Huebner, J, Rodriguiz, R, Wetsel, W, Kraus, V, and Guilak, F. "Omega-3 Fatty Acids Mitigate Obesity-induced Osteoarthritis And Accelerate Wound Repair." Orthopedic Research Society. New Orleans, LA. 2014.
- Journal Articles
  - Leung, YY, Huebner, JL, Haaland, B, Wong, SBS, and Kraus, VB. "Synovial fluid pro-inflammatory profile differs according to the characteristics of knee pain." Osteoarthritis and cartilage 25, no. 9 (September 2017): 1420-1427. Full Text
  - Wu, C-L, McNeill, J, Goon, K, Little, D, Kimmerling, K, Huebner, J, Kraus, V, and Guilak, F. "Conditional Macrophage Depletion Increases Inflammation and Does Not Inhibit the Development of Osteoarthritis in Obese Macrophage Fas-Induced Apoptosis-Transgenic Mice." Arthritis & rheumatology (Hoboken, N.J.) 69, no. 9 (September 2017): 1772-1783. Full Text
  - Hsueh, M-F, Kraus, VB, and Önnerfjord, P. "Cartilage matrix remodelling differs by disease state and joint type." European cells & materials 34 (August 24, 2017): 70-82. Full Text
  - Deveza, LA, Kraus, VB, Collins, JE, Guermazi, A, Roemer, FW, Bowes, M, Nevitt, MC, Ladel, C, and Hunter, DJ. "Association Between Biochemical Markers of Bone Turnover and Bone Changes on Imaging: Data From the Osteoarthritis Initiative." Arthritis care & research 69, no. 8 (August 2017): 1179-1191. Full Text
  - Nwosu, LN, Allen, M, Wyatt, L, Huebner, JL, Chapman, V, Walsh, DA, and Kraus, VB. "Pain prediction by serum biomarkers of bone turnover in people with knee osteoarthritis: an observational study of TRAcP5b and cathepsin K in OA." Osteoarthritis and cartilage 25, no. 6 (June 2017): 858-865. Full Text
  - Adams, SB, Leimer, EM, Setton, LA, Bell, RD, Easley, ME, Huebner, JL, Stabler, TV, Kraus, VB, Olson, SA, and Nettles, DL. "Inflammatory Microenvironment Persists After Bone Healing in Intra-articular Ankle Fractures." Foot & ankle international 38, no. 5 (May 2017): 479-484. Full Text
  - Liu, B, Goode, AP, Carter, TE, Utturkar, GM, Huebner, JL, Taylor, DC, Moorman, CT, Garrett, WE, Kraus, VB, Guilak, F, DeFrate, LE, and McNulty, AL. "Matrix metalloproteinase activity and prostaglandin E2 are elevated in the synovial fluid of meniscus tear patients." Connective tissue research 58, no. 3-4 (May 2017): 305-316. Full Text
  - Huang, ZY, and Kraus, VB. "Reply to Stausholm et al.'s letter to the editor regarding our published study entitled, "Effectiveness of low-level laser therapy in patients with knee osteoarthritis: a systematic review and meta-analysis"." Osteoarthritis and cartilage 25, no. 4 (April 2017): e11-e14. (Letter) Full Text
  - Lattermann, C, Jacobs, CA, Bunnell, MP, Jochimsen, KN, Abt, JP, Reinke, EK, Gammon, LG, Huebner, JL, Kraus, VB, and Spindler, KP. "Logistical challenges and design considerations for studies using acute anterior cruciate ligament injury as a potential model for early posttraumatic osteoarthritis." Journal of orthopaedic research : official publication of the Orthopaedic Research Society 35, no. 3 (March 2017): 641-650. Full Text
  - AbouAssi, H, Connelly, MA, Bateman, LA, Tune, KN, Huebner, JL, Kraus, VB, Winegar, DA, Otvos, JD, Kraus, WE, and Huffman, KM. "Does a lack of physical activity explain the rheumatoid arthritis lipid profile?." Lipids in health and disease 16, no. 1 (February 10, 2017): 39-. Full Text
  - Lattermann, C, Jacobs, CA, Proffitt Bunnell, M, Huston, LJ, Gammon, LG, Johnson, DL, Reinke, EK, Huebner, JL, Kraus, VB, and Spindler, KP. "A Multicenter Study of Early Anti-inflammatory Treatment in Patients With Acute Anterior Cruciate Ligament Tear." The American journal of sports medicine 45, no. 2 (February 2017): 325-333. Full Text
  - Lv, Y-B, Zhu, P-F, Yin, Z-X, Kraus, VB, Threapleton, D, Chei, C-L, Brasher, MS, Zhang, J, Qian, H-Z, Mao, C, Matchar, DB, Luo, J-S, Zeng, Y, and Shi, X-M. "A U-shaped Association Between Blood Pressure and Cognitive Impairment in Chinese Elderly." Journal of the American Medical Directors Association 18, no. 2 (February 2017): 193.e7-193.e13. Full Text
  - Huffman, KM, Jessee, R, Andonian, B, Davis, BN, Narowski, R, Huebner, JL, Kraus, VB, McCracken, J, Gilmore, BF, Tune, KN, Campbell, M, Koves, TR, Muoio, DM, Hubal, MJ, and Kraus, WE. "Molecular alterations in skeletal muscle in rheumatoid arthritis are related to disease activity, physical inactivity, and disability." Arthritis research & therapy 19, no. 1 (January 23, 2017): 12-. Full Text Open Access Copy
  - Gupta, D, Wen, JC, Huebner, JL, Stinnett, S, Kraus, VB, Tseng, HC, and Walsh, M. "Cytokine biomarkers in tear film for primary open-angle glaucoma." Clinical ophthalmology (Auckland, N.Z.) 11 (January 2017): 411-416. Full Text
  - Kraus, VB, Collins, JE, Hargrove, D, Losina, E, Nevitt, M, Katz, JN, Wang, SX, Sandell, LJ, Hoffmann, SC, Hunter, DJ, and OA Biomarkers Consortium, . "Predictive validity of biochemical biomarkers in knee osteoarthritis: data from the FNIH OA Biomarkers Consortium." Annals of the rheumatic diseases 76, no. 1 (January 2017): 186-195. Full Text
  - Kraus, VB, Hargrove, DE, Hunter, DJ, Renner, JB, and Jordan, JM. "Establishment of reference intervals for osteoarthritis-related soluble biomarkers: the FNIH/OARSI OA Biomarkers Consortium." ANNALS OF THE RHEUMATIC DISEASES 76, no. 1 (January 2017): 179-185. Full Text Link to Item
  - Stabler, TV, Huang, Z, Montell, E, Vergés, J, and Kraus, VB. "Chondroitin sulphate inhibits NF-κB activity induced by interaction of pathogenic and damage associated molecules." Osteoarthritis and cartilage 25, no. 1 (January 2017): 166-174. Full Text
  - Taylor, AM, Hsueh, M-F, Ranganath, LR, Gallagher, JA, Dillon, JP, Huebner, JL, Catterall, JB, and Kraus, VB. "Cartilage biomarkers in the osteoarthropathy of alkaptonuria reveal low turnover and accelerated ageing." Rheumatology (Oxford, England) 56, no. 1 (January 2017): 156-164. Full Text
  - Karsdal, MA, Michaelis, M, Ladel, C, Siebuhr, AS, Bihlet, AR, Andersen, JR, Guehring, H, Christiansen, C, Bay-Jensen, AC, and Kraus, VB. "Disease-modifying treatments for osteoarthritis (DMOADs) of the knee and hip: lessons learned from failures and opportunities for the future." Osteoarthritis and cartilage 24, no. 12 (December 2016): 2013-2021. (Review) Full Text
  - Roemer, FW, Guermazi, A, Collins, JE, Losina, E, Nevitt, MC, Lynch, JA, Katz, JN, Kwoh, CK, Kraus, VB, and Hunter, DJ. "Semi-quantitative MRI biomarkers of knee osteoarthritis progression in the FNIH biomarkers consortium cohort - Methodologic aspects and definition of change." BMC musculoskeletal disorders 17, no. 1 (November 10, 2016): 466-. Full Text
  - Kraus, WE, Pieper, CF, Huffman, KM, Thompson, DK, Kraus, VB, Morey, MC, Cohen, HJ, Ravussin, E, Redman, LM, Bain, JR, Stevens, RD, and Newgard, CB. "Association of Plasma Small-Molecule Intermediate Metabolites With Age and Body Mass Index Across Six Diverse Study Populations." The journals of gerontology. Series A, Biological sciences and medical sciences 71, no. 11 (November 2016): 1507-1513. Full Text
  - Castaño-Betancourt, MC, Evans, DS, Ramos, YFM, Boer, CG, Metrustry, S, Liu, Y, den Hollander, W, van Rooij, J, Kraus, VB, Yau, MS, Mitchell, BD, Muir, K, Hofman, A, Doherty, M, Doherty, S, Zhang, W, Kraaij, R, Rivadeneira, F, Barrett-Connor, E, Maciewicz, RA, Arden, N, Nelissen, RGHH, Kloppenburg, M, Jordan, JM, Nevitt, MC, Slagboom, EP, Hart, DJ, Lafeber, F, Styrkarsdottir, U, Zeggini, E, Evangelou, E, Spector, TD, Uitterlinden, AG, Lane, NE, Meulenbelt, I, Valdes, AM, and van Meurs, JBJ. "Novel Genetic Variants for Cartilage Thickness and Hip Osteoarthritis." PLoS genetics 12, no. 10 (October 4, 2016): e1006260-. Full Text
  - Collins, JE, Losina, E, Nevitt, MC, Roemer, FW, Guermazi, A, Lynch, JA, Katz, JN, Kent Kwoh, C, Kraus, VB, and Hunter, DJ. "Semiquantitative Imaging Biomarkers of Knee Osteoarthritis Progression: Data From the Foundation for the National Institutes of Health Osteoarthritis Biomarkers Consortium." Arthritis & rheumatology (Hoboken, N.J.) 68, no. 10 (October 2016): 2422-2431. Full Text
  - Huang, ZY, Stabler, T, Pei, FX, and Kraus, VB. "Both systemic and local lipopolysaccharide (LPS) burden are associated with knee OA severity and inflammation." Osteoarthritis and cartilage 24, no. 10 (October 2016): 1769-1775. Full Text
  - Fu, Y, Huebner, JL, Kraus, VB, and Griffin, TM. "Effect of Aging on Adipose Tissue Inflammation in the Knee Joints of F344BN Rats." The journals of gerontology. Series A, Biological sciences and medical sciences 71, no. 9 (September 2016): 1131-1140. Full Text
  - Huebner, JL, Landerman, LR, Somers, TJ, Keefe, FJ, Guilak, F, Blumenthal, JA, Caldwell, DS, and Kraus, VB. "Exploratory secondary analyses of a cognitive-behavioral intervention for knee osteoarthritis demonstrate reduction in biomarkers of adipocyte inflammation." Osteoarthritis and cartilage 24, no. 9 (September 2016): 1528-1534. Full Text
  - Hunter, D, Nevitt, M, Lynch, J, Kraus, VB, Katz, JN, Collins, JE, Bowes, M, Guermazi, A, Roemer, FW, Losina, E, and FNIH OA Biomarkers Consortium, . "Longitudinal validation of periarticular bone area and 3D shape as biomarkers for knee OA progression? Data from the FNIH OA Biomarkers Consortium." Annals of the rheumatic diseases 75, no. 9 (September 2016): 1607-1614. Full Text
  - Kraus, VB, McDaniel, G, Huebner, JL, Stabler, TV, Pieper, CF, Shipes, SW, Petry, NA, Low, PS, Shen, J, McNearney, TA, and Mitchell, P. "Direct in vivo evidence of activated macrophages in human osteoarthritis." OSTEOARTHRITIS AND CARTILAGE 24, no. 9 (September 2016): 1613-1621. Full Text Link to Item
  - Leung, Y-Y, and Kraus, VB. "Impact of glomerular filtration rate in colchicine toxicity." Seminars in arthritis and rheumatism 45, no. 6 (June 2016): e25-. (Letter) Full Text
  - Bartlett, DB, Connelly, MA, AbouAssi, H, Bateman, LA, Tune, KN, Huebner, JL, Kraus, VB, Winegar, DA, Otvos, JD, Kraus, WE, and Huffman, KM. "A novel inflammatory biomarker, GlycA, associates with disease activity in rheumatoid arthritis and cardio-metabolic risk in BMI-matched controls." Arthritis research & therapy 18 (April 2016): 86-. Full Text Open Access Copy
  - Huebner, JL, Furman, BD, Manson, MJ, Kimmerling, KA, Olson, SA, Guilak, F, DeFrate, LE, Zura, RD, Reilly, RM, and Kraus, VB. "ACUTE INFLAMMATORY RESPONSE AFTER SEVERE JOINT INJURY POTENTIALLY INVOLVED IN THE DEVELOPMENT OF POST-TRAUMATIC ARTHRITIS." OSTEOARTHRITIS AND CARTILAGE 24 (April 2016): S79-S80. Link to Item
  - Bowles, RD, Karikari, IO, VanDerwerken, DN, Sinclair, MS, Bell, RD, Riebe, KJ, Huebner, JL, Kraus, VB, Sempowski, GD, and Setton, LA. "In vivo luminescent imaging of NF-κB activity and NF-κB-related serum cytokine levels predict pain sensitivities in a rodent model of peripheral neuropathy." European journal of pain (London, England) 20, no. 3 (March 2016): 365-376. Full Text
  - Lv, Y-B, Yin, ZX, Chei, C-L, Brasher, MS, Zhang, J, Kraus, VB, Qian, F, Shi, X-M, Matchar, DB, and Zeng, Y. "Serum Cholesterol Levels within the High Normal Range Are Associated with Better Cognitive Performance among Chinese Elderly." The journal of nutrition, health & aging 20, no. 3 (March 2016): 280-287. Full Text
  - Lv, YB, Yin, ZX, Chei, CL, Brasher, MS, Zhang, J, Kraus, VB, Qian, F, Shi, X, Matchar, DB, and Zeng, Y. "Serum cholesterol levels within the high normal range are associated with better cognitive performance among Chinese elderly." Journal of Nutrition, Health and Aging 20, no. 3 (March 1, 2016): 280-287. Full Text Open Access Copy
  - Catterall, JB, Zura, RD, Bolognesi, MP, and Kraus, VB. "Aspartic acid racemization reveals a high turnover state in knee compared with hip osteoarthritic cartilage." Osteoarthritis and cartilage 24, no. 2 (February 2016): 374-381. Full Text
  - Hsueh, M-F, Khabut, A, Kjellström, S, Önnerfjord, P, and Kraus, VB. "Elucidating the Molecular Composition of Cartilage by Proteomics." Journal of proteome research 15, no. 2 (February 2016): 374-388. Full Text Open Access Copy
  - Huang, Z, and Kraus, VB. "Does lipopolysaccharide-mediated inflammation have a role in OA?." Nature reviews. Rheumatology 12, no. 2 (February 2016): 123-129. (Review) Full Text
  - Peterson, MJ, Thompson, DK, Pieper, CF, Morey, MC, Kraus, VB, Kraus, WE, Sullivan, P, Fillenbaum, G, and Cohen, HJ. "A Novel Analytic Technique to Measure Associations Between Circulating Biomarkers and Physical Performance Across the Adult Life Span." The journals of gerontology. Series A, Biological sciences and medical sciences 71, no. 2 (February 2016): 196-202. Full Text
  - Olson, SA, Furman, BD, Kraus, VB, Huebner, JL, and Guilak, F. "Reply to "Does progranulin account for the opposite effects of etanercept and infliximab/adalimumab in osteoarthritis?" by Wei et al." Journal of orthopaedic research : official publication of the Orthopaedic Research Society 34, no. 1 (January 2016): 15-16. (Letter) Full Text
  - Siebuhr, AS, Bay-Jensen, AC, Jordan, JM, Kjelgaard-Petersen, CF, Christiansen, C, Abramson, SB, Attur, M, Berenbaum, F, Kraus, V, and Karsdal, MA. "Inflammation (or synovitis)-driven osteoarthritis: an opportunity for personalizing prognosis and treatment?." Scandinavian journal of rheumatology 45, no. 2 (January 2016): 87-98. (Review) Full Text
  - Huang, Z, Ma, J, Chen, J, Shen, B, Pei, F, and Kraus, VB. "The effectiveness of low-level laser therapy for nonspecific chronic low back pain: a systematic review and meta-analysis." Arthritis research & therapy 17 (December 15, 2015): 360-. (Review) Full Text Open Access Copy
  - Stabler, T, Zura, RD, Hsueh, M-F, and Kraus, VB. "Xanthine oxidase injurious response in acute joint injury." CLINICA CHIMICA ACTA 451 (December 7, 2015): 170-174. Full Text Open Access Copy Link to Item
  - Eckstein, F, Collins, JE, Nevitt, MC, Lynch, JA, Kraus, VB, Katz, JN, Losina, E, Wirth, W, Guermazi, A, Roemer, FW, Hunter, DJ, and FNIH OA Biomarkers Consortium, . "Brief Report: Cartilage Thickness Change as an Imaging Biomarker of Knee Osteoarthritis Progression: Data From the Foundation for the National Institutes of Health Osteoarthritis Biomarkers Consortium." Arthritis & rheumatology (Hoboken, N.J.) 67, no. 12 (December 2015): 3184-3189. Full Text
  - Kraus, VB, Kilfoil, TM, Hash, TW, McDaniel, G, Renner, JB, Carrino, JA, and Adams, S. "Atlas of radiographic features of osteoarthritis of the ankle and hindfoot." Osteoarthritis and cartilage 23, no. 12 (December 2015): 2059-2085. (Review) Full Text
  - Leung, YY, Yao Hui, LL, and Kraus, VB. "Colchicine--Update on mechanisms of action and therapeutic uses." Seminars in arthritis and rheumatism 45, no. 3 (December 2015): 341-350. (Review) Full Text
  - Montell, E, Stabler, T, Verges Milano, J, and Kraus, VB. "ATTENTUATION OF HYALURONAN FRAGMENT INDUCED INFLAMMATORY RESPONSE IN MACROPHAGES BY CHONDROITIN SULPHATE." BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY 117 (December 2015): 11-11. Link to Item
  - Adams, SB, Setton, LA, Bell, RD, Easley, ME, Huebner, JL, Stabler, T, Kraus, VB, Leimer, EM, Olson, SA, and Nettles, DL. "Inflammatory Cytokines and Matrix Metalloproteinases in the Synovial Fluid After Intra-articular Ankle Fracture." Foot & ankle international 36, no. 11 (November 2015): 1264-1271. Full Text
  - Attur, M, Krasnokutsky, S, Statnikov, A, Samuels, J, Li, Z, Friese, O, Hellio Le Graverand-Gastineau, M-P, Rybak, L, Kraus, VB, Jordan, JM, Aliferis, CF, and Abramson, SB. "Low-grade inflammation in symptomatic knee osteoarthritis: prognostic value of inflammatory plasma lipids and peripheral blood leukocyte biomarkers." Arthritis & rheumatology (Hoboken, N.J.) 67, no. 11 (November 2015): 2905-2915. Full Text
  - Attur, M, Statnikov, A, Samuels, J, Li, Z, Alekseyenko, AV, Greenberg, JD, Krasnokutsky, S, Rybak, L, Lu, QA, Todd, J, Zhou, H, Jordan, JM, Kraus, VB, Aliferis, CF, and Abramson, SB. "Plasma levels of interleukin-1 receptor antagonist (IL1Ra) predict radiographic progression of symptomatic knee osteoarthritis." Osteoarthritis and cartilage 23, no. 11 (November 2015): 1915-1924. Full Text
  - Daghestani, HN, and Kraus, VB. "Inflammatory biomarkers in osteoarthritis." Osteoarthritis and cartilage 23, no. 11 (November 2015): 1890-1896. (Review) Full Text
  - Hsu, Y-H, Liu, Y, Hannan, MT, Maixner, W, Smith, SB, Diatchenko, L, Golightly, YM, Menz, HB, Kraus, VB, Doherty, M, Wilson, AG, and Jordan, JM. "Genome-wide association meta-analyses to identify common genetic variants associated with hallux valgus in Caucasian and African Americans." Journal of medical genetics 52, no. 11 (November 2015): 762-769. Full Text
  - Wu, C-L, Jain, D, McNeill, JN, Little, D, Anderson, JA, Huebner, JL, Kraus, VB, Rodriguiz, RM, Wetsel, WC, and Guilak, F. "Dietary fatty acid content regulates wound repair and the pathogenesis of osteoarthritis following joint injury." Annals of the rheumatic diseases 74, no. 11 (November 2015): 2076-2083. Full Text
  - Huang, Z, Chen, J, Ma, J, Shen, B, Pei, F, and Kraus, VB. "Effectiveness of low-level laser therapy in patients with knee osteoarthritis: a systematic review and meta-analysis." Osteoarthritis and cartilage 23, no. 9 (September 2015): 1437-1444. (Review) Full Text
  - Huang, Z, Chen, J, Ma, J, Shen, B, Pei, F, and Kraus, VB. "Effectiveness of low-level laser therapy in patients with knee osteoarthritis: a systematic review and meta-analysis." OSTEOARTHRITIS AND CARTILAGE 23, no. 9 (September 2015): 1437-1444. Full Text Link to Item
  - Olson, SA, Furman, BD, Kraus, VB, Huebner, JL, and Guilak, F. "Therapeutic opportunities to prevent post-traumatic arthritis: Lessons from the natural history of arthritis after articular fracture." Journal of orthopaedic research : official publication of the Orthopaedic Research Society 33, no. 9 (September 2015): 1266-1277. Full Text
  - Kraus, VB, Blanco, FJ, Englund, M, Karsdal, MA, and Lohmander, LS. "Call for standardized definitions of osteoarthritis and risk stratification for clinical trials and clinical use." Osteoarthritis and cartilage 23, no. 8 (August 2015): 1233-1241. (Review) Full Text
  - Fu, Q, Cao, J, Renner, JB, Jordan, JM, Caterson, B, Duance, V, Luo, M, and Kraus, VB. "Radiographic features of hand osteoarthritis in adult Kashin-Beck Disease (KBD): the Yongshou KBD study." Osteoarthritis and cartilage 23, no. 6 (June 2015): 868-873. Full Text
  - Furman, BD, Kimmerling, KA, Zura, RD, Reilly, RM, Zlowodzki, MP, Huebner, JL, Kraus, VB, Guilak, F, and Olson, SA. "Articular ankle fracture results in increased synovitis, synovial macrophage infiltration, and synovial fluid concentrations of inflammatory cytokines and chemokines." Arthritis & rheumatology (Hoboken, N.J.) 67, no. 5 (May 2015): 1234-1239. Full Text
  - Kloppenburg, M, Maheu, E, Kraus, VB, Cicuttini, F, Doherty, M, Dreiser, R-L, Henrotin, Y, Jiang, G-L, Mandl, L, Martel-Pelletier, J, Nelson, AE, Neogi, T, Pelletier, J-P, Punzi, L, Ramonda, R, Simon, LS, Wang, S, and OARSI Hand Clinical Trial Recommendations Work Group, . "OARSI Clinical Trials Recommendations: Design and conduct of clinical trials for hand osteoarthritis." Osteoarthritis and cartilage 23, no. 5 (May 2015): 772-786. (Review) Full Text
  - Kraus, VB, Blanco, FJ, Englund, M, Henrotin, Y, Lohmander, LS, Losina, E, Önnerfjord, P, and Persiani, S. "OARSI Clinical Trials Recommendations: Soluble biomarker assessments in clinical trials in osteoarthritis." Osteoarthritis and cartilage 23, no. 5 (May 2015): 686-697. (Review) Full Text
  - Leung, Y-Y, Thumboo, J, Wong, BS, Haaland, B, Chowbay, B, Chakraborty, B, Tan, MH, and Kraus, VB. "Colchicine effectiveness in symptom and inflammation modification in knee osteoarthritis (COLKOA): study protocol for a randomized controlled trial." Trials 16 (April 30, 2015): 200-. Full Text Open Access Copy
  - Chou, C-H, Lee, MTM, Song, I-W, Lu, L-S, Shen, H-C, Lee, C-H, Wu, J-Y, Chen, Y-T, Kraus, VB, and Wu, C-C. "Insights into osteoarthritis progression revealed by analyses of both knee tibiofemoral compartments." Osteoarthritis and cartilage 23, no. 4 (April 2015): 571-580. Full Text
  - Chou, CH, Lee, MTM, Song, IW, Lu, LS, Shen, HC, Lee, CH, Wu, JY, Chen, YT, Kraus, VB, and Wu, CC. "Insights into osteoarthritis progression revealed by analyses of both knee tibiofemoral compartments." Osteoarthritis and Cartilage 23, no. 4 (April 1, 2015): 571-580. Full Text
  - Daghestani, HN, Pieper, CF, and Kraus, VB. "Soluble macrophage biomarkers indicate inflammatory phenotypes in patients with knee osteoarthritis." Arthritis & rheumatology (Hoboken, N.J.) 67, no. 4 (April 2015): 956-965. Full Text
  - Karsdal, MA, Bihlet, A, Byrjalsen, I, Alexandersen, P, Ladel, C, Michaels, M, Andersen, JR, Riis, BJ, Kraus, V, Bay-Jensen, AC, and Christiansen, C. "OA phenotypes, rather than disease stage, drive structural progression--identification of structural progressors from 2 phase III randomized clinical studies with symptomatic knee OA." Osteoarthritis and cartilage 23, no. 4 (April 2015): 550-558. Full Text
  - Vovos, TJ, Furman, BD, Huebner, JL, Kimmerling, KA, Utturkar, GM, DeFrate, LE, Kraus, VB, Guilak, F, and Olson, SA. "JOINT INCONGRUITY AND BIOMARKERS OF BONE METABOLISM AS PREDICTORS OF POST-TRAUMATIC ARTHRITIS IN MICE." OSTEOARTHRITIS AND CARTILAGE 23 (April 2015): A242-A243. Link to Item
  - Lv, Y-B, Yin, Z-X, Chei, C-L, Qian, H-Z, Kraus, VB, Zhang, J, Brasher, MS, Shi, X-M, Matchar, DB, and Zeng, Y. "Low-density lipoprotein cholesterol was inversely associated with 3-year all-cause mortality among Chinese oldest old: data from the Chinese Longitudinal Healthy Longevity Survey." Atherosclerosis 239, no. 1 (March 2015): 137-142. Full Text
  - Orlowsky, EW, and Kraus, VB. "The role of innate immunity in osteoarthritis: when our first line of defense goes on the offensive." The Journal of rheumatology 42, no. 3 (March 2015): 363-371. (Review) Full Text
  - Kimmerling, KA, Furman, BD, Mangiapani, DS, Moverman, MA, Sinclair, SM, Huebner, JL, Chilkoti, A, Kraus, VB, Setton, LA, Guilak, F, and Olson, SA. "Sustained intra-articular delivery of IL-1RA from a thermally-responsive elastin-like polypeptide as a therapy for post-traumatic arthritis." European cells & materials 29 (January 31, 2015): 124-139.
  - Band, PA, Heeter, J, Wisniewski, H-G, Liublinska, V, Pattanayak, CW, Karia, RJ, Stabler, T, Balazs, EA, and Kraus, VB. "Hyaluronan molecular weight distribution is associated with the risk of knee osteoarthritis progression." Osteoarthritis and cartilage 23, no. 1 (January 2015): 70-76. Full Text
  - Leung, Y-Y, Thumboo, J, Wong, SB, Haaland, B, Chowbay, B, Chakraborty, B, Tan, MH, and Kraus, VB. "Colchicine effectiveness in symptom and inflammation modification in knee osteoarthritis (COLKOA): Study protocol for a randomized controlled trial." Trials 16, no. 1 (2015). Full Text
  - AbouAssi, H, Tune, KN, Gilmore, B, Bateman, LA, McDaniel, G, Muehlbauer, M, Huebner, JL, Hoenig, HM, Kraus, VB, St Clair, EW, Kraus, WE, and Huffman, KM. "Adipose depots, not disease-related factors, account for skeletal muscle insulin sensitivity in established and treated rheumatoid arthritis." The Journal of rheumatology 41, no. 10 (October 2014): 1974-1979. Full Text
  - Attur, M, Statnikov, A, Samuels, SK, Kraus, VB, Jordan, J, Mitchell, BD, Yau, M, Patel, J, Aliferis, CF, Hochberg, MC, Samuels, J, and Abramson, SB. "Elevated Peripheral Blood Leukocyte Inflammatory Gene Expression in Radiographic Progressors with Symptomatic Knee Osteoarthritis: NYU and OAI Cohorts." ARTHRITIS & RHEUMATOLOGY 66 (October 2014): S34-S34. Link to Item
  - Hunter, DJ, Collins, JE, Nevitt, MC, Lynch, JA, Kraus, VB, Katz, JN, Losina, E, Roemer, F, Guermazi, A, Wirth, W, and Eckstein, F. "Preliminary Assessment of Predictive Validity of Cartilage Thickness MRI Biomarkers in Knee OA - the Fnih OA Biomarkers Consortium." ARTHRITIS & RHEUMATOLOGY 66 (October 2014): S87-S88. Link to Item
  - Montell, E, Verges, J, Orlowsky, EW, Stabler, TV, and Kraus, BV. "MONOSODIUM URATE CRYSTAL INDUCED MACROPHAGE INFLAMMATION IS ATTENUATED BY CHONDROITIN SULFATE: PRE-CLINICAL MODEL FOR GOUT PROPHYLAXIS?." BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY 115 (October 2014): 21-21. Link to Item
  - Orlowsky, EW, Stabler, TV, Montell, E, Vergés, J, and Kraus, VB. "Monosodium urate crystal induced macrophage inflammation is attenuated by chondroitin sulphate: pre-clinical model for gout prophylaxis?." BMC musculoskeletal disorders 15 (September 27, 2014): 318-. Full Text Open Access Copy
  - Huebner, JL, Bay-Jensen, AC, Huffman, KM, He, Y, Leeming, DJ, McDaniel, GE, Karsdal, MA, and Kraus, VB. "Alpha C-telopeptide of type I collagen is associated with subchondral bone turnover and predicts progression of joint space narrowing and osteophytes in osteoarthritis." Arthritis & rheumatology (Hoboken, N.J.) 66, no. 9 (September 2014): 2440-2449. Full Text
  - Montell, E, Verges, J, Orlowsky, EW, Stabler, TV, and Kraus, BV. "MONOSODIUM URATE CRYSTAL INDUCED MACROPHAGE INFLAMMATION IS ATTENUATED BY CHONDROITIN SULFATE: PRE-CLINICAL MODEL FOR GOUT PROPHYLAXIS?." BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY 115 (September 2014): 34-34. Link to Item
  - Yin, Z, Shi, X, Kraus, VB, Brasher, MS, Chen, H, Liu, Y, Lv, Y, and Zeng, Y. "Gender-dependent association of body mass index and waist circumference with disability in the Chinese oldest old." Obesity (Silver Spring, Md.) 22, no. 8 (August 2014): 1918-1925. Full Text Open Access Copy
  - Furman, BD, Mangiapani, DS, Zeitler, E, Bailey, KN, Horne, PH, Huebner, JL, Kraus, VB, Guilak, F, and Olson, SA. "Targeting pro-inflammatory cytokines following joint injury: acute intra-articular inhibition of interleukin-1 following knee injury prevents post-traumatic arthritis." Arthritis research & therapy 16, no. 3 (June 25, 2014): R134-. Full Text Open Access Copy
  - Aslam, I, Perjar, I, Shi, XA, Renner, JB, Kraus, VB, Golightly, YM, Jordan, JM, and Nelson, AE. "Associations between biomarkers of joint metabolism, hand osteoarthritis, and hand pain and function: the Johnston County Osteoarthritis Project." The Journal of rheumatology 41, no. 5 (May 2014): 938-944. Full Text
  - Bowles, RD, Mata, BA, Bell, RD, Mwangi, TK, Huebner, JL, Kraus, VB, and Setton, LA. "In vivo luminescence imaging of NF-κB activity and serum cytokine levels predict pain sensitivities in a rodent model of osteoarthritis." Arthritis & rheumatology (Hoboken, N.J.) 66, no. 3 (March 2014): 637-646. Full Text Open Access Copy
  - Kraus, VB. "Osteoarthritis: The zinc link." Nature 507, no. 7493 (March 2014): 441-442. Full Text
  - Lotz, M, Martel-Pelletier, J, Christiansen, C, Brandi, ML, Bruyère, O, Chapurlat, R, Collette, J, Cooper, C, Giacovelli, G, Kanis, JA, Karsdal, MA, Kraus, V, Lems, WF, Meulenbelt, I, Pelletier, JP, Raynauld, JP, Reiter-Niesert, S, Rizzoli, R, Sandell, LJ, Van Spil, WE, and Reginster, JY. "Value of biomarkers in osteoarthritis: Current status and perspectives." Postgraduate Medical Journal 90, no. 1061 (March 1, 2014): 171-178. Full Text
  - Hunter, DJ, Nevitt, M, Losina, E, and Kraus, V. "Biomarkers for osteoarthritis: current position and steps towards further validation." Best practice & research. Clinical rheumatology 28, no. 1 (February 2014): 61-71. (Review) Full Text
  - Hunter, DJ, Nevitt, M, Losina, E, and Kraus, V. "Biomarkers for osteoarthritis: Current position and steps towards further validation." Best Practice & Research Clinical Rheumatology 28, no. 1 (February 2014): 61-71. Full Text
  - Karsdal, MA, Bay-Jensen, AC, Lories, RJ, Abramson, S, Spector, T, Pastoureau, P, Christiansen, C, Attur, M, Henriksen, K, Goldring, SR, and Kraus, V. "The coupling of bone and cartilage turnover in osteoarthritis: opportunities for bone antiresorptives and anabolics as potential treatments?." Annals of the Rheumatic Diseases 73, no. 2 (February 2014): 336-348. Full Text
  - Wisniewski, H-G, Colón, E, Liublinska, V, Karia, RJ, Stabler, TV, Attur, M, Abramson, SB, Band, PA, and Kraus, VB. "TSG-6 activity as a novel biomarker of progression in knee osteoarthritis." Osteoarthritis Cartilage 22, no. 2 (February 2014): 235-241. Full Text Link to Item
  - Wisniewski, HG, Colón, E, Liublinska, V, Karia, RJ, Stabler, TV, Attur, M, Abramson, SB, Band, PA, and Kraus, VB. "TSG-6 activity as a novel biomarker of progression in kneeosteoarthritis." Osteoarthritis and Cartilage 22, no. 2 (February 1, 2014): 235-241. Full Text
  - Evans, CH, Kraus, VB, and Setton, LA. "Progress in intra-articular therapy." Nature Reviews Rheumatology 10, no. 1 (January 1, 2014): 11-22. (Review) Full Text
  - Evans, CH, Kraus, VB, and Setton, LA. "Progress in intra-articular therapy." Nat Rev Rheumatol 10, no. 1 (January 2014): 11-22. (Review) Full Text Open Access Copy Link to Item
  - Hsueh, M-F, O nnerfjord, P, and Kraus, VB. "Biomarkers and proteomic analysis of osteoarthritis (Accepted)." Matrix Biology (2014). Full Text
  - Karsdal, MA, Bay-Jensen, AC, Lories, RJ, Abramson, S, Spector, T, Pastoureau, P, Christiansen, C, Attur, M, Henriksen, K, Goldring, SR, and Kraus, V. "The coupling of bone and cartilage turnover in osteoarthritis: Opportunities for bone antiresorptives and anabolics as potential treatments?." Annals of the Rheumatic Diseases 73, no. 2 (2014): 336-348. Full Text
  - Karsdal, MA, Christiansen, C, Ladel, C, Henriksen, K, Kraus, VB, and Bay-Jensen, AC. "Osteoarthritis--a case for personalized health care?." Osteoarthritis Cartilage 22, no. 1 (January 2014): 7-16. (Review) Full Text Link to Item
  - Karsdal, MA, Christiansen, C, Ladel, C, Henriksen, K, Kraus, VB, and Bay-Jensen, AC. "Osteoarthritis - a case for personalized health care?." Osteoarthritis and Cartilage 22, no. 1 (January 1, 2014): 7-16. (Review) Full Text
  - Nelson, AE, Elstad, E, DeVellis, RF, Schwartz, TA, Golightly, YM, Renner, JB, Conaghan, PG, Kraus, VB, and Jordan, JM. "Composite measures of multi-joint symptoms, but not of radiographic osteoarthritis, are associated with functional outcomes: the Johnston County Osteoarthritis Project." Disability and rehabilitation 36, no. 4 (January 2014): 300-306. Full Text
  - Olson, SA, Horne, P, Furman, B, Huebner, J, Al-Rashid, M, Kraus, VB, and Guilak, F. "The role of cytokines in posttraumatic arthritis." The Journal of the American Academy of Orthopaedic Surgeons 22, no. 1 (January 2014): 29-37. (Review) Full Text
  - Song, I-W, Li, W-R, Chen, L-Y, Shen, L-F, Liu, K-M, Yen, JJY, Chen, Y-J, Chen, Y-J, Kraus, VB, Wu, J-Y, Lee, MTM, and Chen, Y-T. "Palmitoyl acyltransferase, Zdhhc13, facilitates bone mass acquisition by regulating postnatal epiphyseal development and endochondral ossification: a mouse model." PloS one 9, no. 3 (January 2014): e92194-. Full Text Open Access Copy
  - Benjamin, AM, Thompson, JW, Soderblom, EJ, Geromanos, SJ, Henao, R, Kraus, VB, Moseley, MA, and Lucas, JE. "A flexible statistical model for alignment of label-free proteomics data--incorporating ion mobility and product ion information." BMC bioinformatics 14 (December 16, 2013): 364-. Full Text Open Access Copy
  - Bowles, RD, Mata, BA, Bell, RD, Mwangi, TK, Huebner, JL, Kraus, VB, and Setton, LA. "In Vivo luminescent imaging of NF-κB activity and serum cytokine levels predict pain sensitivities in a rodent model of osteoarthritis." Arthritis Rheum (November 18, 2013). Full Text Open Access Copy Link to Item
  - Chou, CH, Wu, CC, Song, IW, Chuang, HP, Lu, LS, Chang, JH, Kuo, SY, Lee, CH, Wu, JY, Chen, YT, Kraus, VB, and Lee, MTM. "Genome-wide expression profiles of subchondral bone in osteoarthritis." Arthritis Research and Therapy 15, no. 6 (November 15, 2013). Full Text Open Access Copy
  - Kraus, VB, Worrell, TW, Renner, JB, Coleman, RE, and Pieper, CF. "High prevalence of contralateral ankle abnormalities in association with knee osteoarthritis and malalignment." Osteoarthritis Cartilage 21, no. 11 (November 2013): 1693-1699. Full Text Link to Item
  - Orlowsky, EW, Stabler, TV, Montell, E, Verges, J, and Kraus, VB. "MONOSODIUM URATE CRYSTAL INDUCED MACROPHAGE INFLAMMATION IS ATTENUATED BY CHONDROITIN SULFATE: PRE-CLINICAL MODEL FOR GOUT PROPHYLAXIS." BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY 113 (October 2013): 21-21. Link to Item
  - Verges, J, Orlowsky, E, Stabler, TV, Montell, E, and Kraus, VB. "THE EFFECTS OF CHONDROITIN SULFATE ON INFLAMMASOME ACTIVATION." BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY 113 (September 2013): 39-39. Link to Item
  - Kraus, VB, Feng, S, Wang, S, White, S, Ainslie, M, Graverand, M-PHL, Brett, A, Eckstein, F, Hunter, DJ, Lane, NE, Taljanovic, MS, Schnitzer, T, and Charles, HC. "Subchondral bone trabecular integrity predicts and changes concurrently with radiographic and magnetic resonance imaging-determined knee osteoarthritis progression." Arthritis Rheum 65, no. 7 (July 2013): 1812-1821. Full Text Link to Item
  - Orlowsky, E, Stabler, TV, Montell, E, Verges, J, and Kraus, VB. "THE EFFECTS OF CHONDROITIN SULPHATE ON INFLAMMASOME ACTIVATION." ANNALS OF THE RHEUMATIC DISEASES 72 (June 2013): 794-795. Link to Item
  - Kimmerling, KA, Furman, BD, Mangiapani, DS, Moverman, MA, Sinclair, SM, Huebner, JL, Kraus, VB, Setton, LA, Guilak, F, and Olson, SA. "PROLONGED LOCAL DELIVERY OF IL-1RA PREVENTS POST-TRAUMATIC ARTHRITIS IN MICE." OSTEOARTHRITIS AND CARTILAGE 21 (April 2013): S30-S31. Link to Item
  - Chou, C-H, Lee, C-H, Lu, L-S, Song, I-W, Chuang, H-P, Kuo, S-Y, Wu, J-Y, Chen, Y-T, Kraus, VB, Wu, C-C, and Lee, MTM. "Direct assessment of articular cartilage and underlying subchondral bone reveals a progressive gene expression change in human osteoarthritic knees." Osteoarthritis Cartilage 21, no. 3 (March 2013): 450-461. Full Text Link to Item
  - Lewis, JS, Furman, BD, Zeitler, E, Huebner, JL, Kraus, VB, Guilak, F, and Olson, SA. "Genetic and cellular evidence of decreased inflammation associated with reduced incidence of posttraumatic arthritis in MRL/MpJ mice." Arthritis Rheum 65, no. 3 (March 2013): 660-670. Full Text Link to Item
  - Nelson, AE, Golightly, YM, Renner, JB, Schwartz, TA, Kraus, VB, Helmick, CG, and Jordan, JM. "Differences in Multijoint Symptomatic Osteoarthritis Phenotypes by Race and Sex: The Johnston County Osteoarthritis Project." ARTHRITIS AND RHEUMATISM 65, no. 2 (February 2013): 373-377. Full Text Link to Item
  - Diekman, BO, Wu, C-L, Louer, CR, Furman, BD, Huebner, JL, Kraus, VB, Olson, SA, and Guilak, F. "Intra-articular delivery of purified mesenchymal stem cells from C57BL/6 or MRL/MpJ superhealer mice prevents posttraumatic arthritis." Cell Transplant 22, no. 8 (2013): 1395-1408. Full Text Link to Item
  - Hunt, MA, Pollock, CL, Kraus, VB, Saxne, T, Peters, S, Huebner, JL, Sayre, EC, and Cibere, J. "Relationships amongst osteoarthritis biomarkers, dynamic knee joint load, and exercise: Results from a randomized controlled pilot study." BMC Musculoskeletal Disorders 14 (2013). Full Text Open Access Copy
  - Hunter, DJ, Eckstein, F, Kraus, VB, Losina, E, Sandell, L, and Guermazi, A. "Imaging Biomarker Validation and Qualification Report: Sixth OARSI Workshop on Imaging in Osteoarthritis combined with Third OA Biomarkers Workshop." Osteoarthritis and Cartilage (2013). Full Text
  - Hunter, DJ, Eckstein, F, Kraus, VB, Losina, E, Sandell, L, and Guermazi, A. "Imaging biomarker validation and qualification report: Sixth oarsi workshop on imaging in osteoarthritis combined with third oa biomarkers workshop." Osteoarthritis and Cartilage 21, no. 7 (2013): 939-942. Full Text
  - Kraus, VB, Worrell, TW, Renner, JB, Coleman, RE, and Pieper, CF. "High prevalence of contralateral ankle abnormalities in association with knee osteoarthritis and malalignment." Osteoarthritis and Cartilage 21, no. 11 (2013): 1693-1699. Full Text
  - Kraus, VB. "Osteoarthritis." Genomic and Personalized Medicine 2 (2013): 983-989. Full Text
  - Lotz, M, Martel-Pelletier, J, Christiansen, C, Brandi, M-L, Bruyère, O, Chapurlat, R, Collette, J, Cooper, C, Giacovelli, G, Kanis, JA, Karsdal, MA, Kraus, V, Lems, WF, Meulenbelt, I, Pelletier, J-P, Raynauld, J-P, Reiter-Niesert, S, Rizzoli, R, Sandell, LJ, Spil, WEV, and Reginster, J-Y. "Value of biomarkers in osteoarthritis: Current status and perspectives." Annals of the Rheumatic Diseases 72, no. 11 (2013): 1756-1763. Full Text
  - Lotz, M, Martel-Pelletier, J, Christiansen, C, Brandi, M-L, Bruyère, O, Chapurlat, R, Collette, J, Cooper, C, Giacovelli, G, Kanis, JA, and al, E. "Value of biomarkers in osteoarthritis: Current status and perspectives." Annals of the Rheumatic Diseases (2013). Full Text
  - Nolan, D, Kraus, WE, Hauser, E, Li, Y-J, Thompson, DK, Johnson, J, Chen, H-C, Nelson, S, Haynes, C, Gregory, SG, Kraus, VB, and Shah, SH. "Genome-wide linkage analysis of cardiovascular disease biomarkers in a large, multigenerational family. (Published online)" PLoS One 8, no. 8 (2013): e71779-. Full Text Open Access Copy Link to Item
  - Goode, AP, Marshall, SW, Kraus, VB, Renner, JB, Stürmer, T, Carey, TS, Irwin, DE, and Jordan, JM. "Association between serum and urine biomarkers and lumbar spine individual radiographic features: the Johnston County Osteoarthritis Project." Osteoarthritis Cartilage 20, no. 11 (November 2012): 1286-1293. Full Text Link to Item
  - Goode, AP, Marshall, SW, Renner, JB, Carey, TS, Kraus, VB, Irwin, DE, Stürmer, T, and Jordan, JM. "Lumbar spine radiographic features and demographic, clinical, and radiographic knee, hip, and hand osteoarthritis." Arthritis Care Res (Hoboken) 64, no. 10 (October 2012): 1536-1544. Full Text Link to Item
  - Louer, CR, Furman, BD, Huebner, JL, Kraus, VB, Olson, SA, and Guilak, F. "Diet-induced obesity significantly increases the severity of posttraumatic arthritis in mice." Arthritis Rheum 64, no. 10 (October 2012): 3220-3230. Full Text Link to Item
  - Somers, TJ, Blumenthal, JA, Guilak, F, Kraus, VB, Schmitt, DO, Babyak, MA, Craighead, LW, Caldwell, DS, Rice, JR, McKee, DC, Shelby, RA, Campbell, LC, Pells, JJ, Sims, EL, Queen, R, Carson, JW, Connelly, M, Dixon, KE, Lacaille, LJ, Huebner, JL, Rejeski, WJ, and Keefe, FJ. "Pain coping skills training and lifestyle behavioral weight management in patients with knee osteoarthritis: a randomized controlled study." Pain 153, no. 6 (June 2012): 1199-1209. Full Text Link to Item
  - Cheng, AWM, Bolognesi, M, and Kraus, VB. "DIO2 modifies inflammatory responses in chondrocytes." Osteoarthritis Cartilage 20, no. 5 (May 2012): 440-445. Full Text Link to Item
  - Allen, KD, Mata, BA, Gabr, MA, Huebner, JL, Adams, SB, Kraus, VB, Schmitt, DO, and Setton, LA. "Kinematic and dynamic gait compensations resulting from knee instability in a rat model of osteoarthritis. (Published online)" Arthritis Res Ther 14, no. 2 (April 17, 2012): R78-. Full Text Open Access Copy Link to Item
  - Kraus, VB, Birmingham, J, Stabler, TV, Feng, S, Taylor, DC, Moorman, CT, Garrett, WE, and Toth, AP. "Effects of intraarticular IL1-Ra for acute anterior cruciate ligament knee injury: a randomized controlled pilot trial (NCT00332254)." Osteoarthritis Cartilage 20, no. 4 (April 2012): 271-278. Full Text Link to Item
  - Catterall, JB, Hsueh, MF, Stabler, TV, McCudden, CR, Bolognesi, M, Zura, R, Jordan, JM, Renner, JB, Feng, S, and Kraus, VB. "Protein modification by deamidation indicates variations in joint extracellular matrix turnover." J Biol Chem 287, no. 7 (February 10, 2012): 4640-4651. Full Text Link to Item
  - Griffin, TM, Huebner, JL, Kraus, VB, Yan, Z, and Guilak, F. "Induction of osteoarthritis and metabolic inflammation by a very high-fat diet in mice: effects of short-term exercise." Arthritis Rheum 64, no. 2 (February 2012): 443-453. Full Text Link to Item
  - Kraus, VB. "Patient Evaluation and OA Study Design: OARSI/Biomarker Qualification." HSS J 8, no. 1 (February 2012): 64-65. Full Text Link to Item
  - Hoch, JM, Mattacola, CG, Kraus, VB, and Lattermann, C. "The role of cartilage degradation biomarkers in understanding the development of post-traumatic osteoarthritis following acute articular cartilage damage - A review." European Musculoskeletal Review 7, no. 3 (2012): 147-150.
  - Huffman, KM, Redman, LM, Landerman, LR, Pieper, CF, Stevens, RD, Muehlbauer, MJ, Wenner, BR, Bain, JR, Kraus, VB, Newgard, CB, Ravussin, E, and Kraus, WE. "Caloric restriction alters the metabolic response to a mixed-meal: results from a randomized, controlled trial." PLoS One 7, no. 4 (2012): e28190-. Full Text Open Access Copy Link to Item
  - Hwang, PY, Allen, KD, Shamji, MF, Jing, L, Mata, BA, Gabr, MA, Huebner, JL, Kraus, VB, Richardson, WJ, and Setton, LA. "Changes in midbrain pain receptor expression, gait and behavioral sensitivity in a rat model of radiculopathy." Open Orthop J 6 (2012): 383-391. Full Text Open Access Copy Link to Item
  - Lekpa, FK, Kraus, VB, and Chevalier, X. "Biologics in Relapsing Polychondritis: A Literature Review." Seminars in Arthritis and Rheumatism 41, no. 5 (2012): 712-719. Full Text
  - Seifer, DR, Furman, BD, Guilak, F, Olson, SA, Brooks, SC, and Kraus, VB. "Corrigendum to "Novel synovial fluid recovery method allows for quantification of a marker of arthritis in mice" [Osteoarthritis and Cartilage 2008;16(12): 1532-1538." Osteoarthritis and Cartilage 20, no. 1 (2012): 68--. Full Text
  - Tenenbaum, JD, Christian, V, Cornish, MA, Dolor, RJ, Dunham, AA, Ginsburg, GS, Kraus, VB, McHutchison, JG, Nahm, ML, Newby, LK, Svetkey, LP, Udayakumar, K, and Califf, RM. "The MURDOCK Study: A long-term initiative for disease reclassification through advanced biomarker discovery and integration with electronic health records." American Journal of Translational Research 4, no. 3 (2012): 291-301.
  - Thompson, DK, Huffman, KM, Kraus, WE, and Kraus, VB. "Critical appraisal of four IL-6 immunoassays." PLoS One 7, no. 2 (2012): e30659-. Full Text Open Access Copy Link to Item
  - Thompson, DK, Sloane, R, Bain, JR, Stevens, RD, Newgard, CB, Pieper, CF, and Kraus, VB. "Daily variation of serum acylcarnitines and amino acids." Metabolomics 8, no. 4 (2012): 556-565. Full Text
  - Yin, Z-X, Shi, X-M, Kraus, VB, Fitzgerald, SM, Qian, H-Z, Xu, J-W, Zhai, Y, Sereny, MD, and Zeng, Y. "High normal plasma triglycerides are associated with preserved cognitive function in chinese oldest-old." Age and Ageing 41, no. 5 (2012): 600-606. Full Text
  - Zhai, Y, Shi, XM, Fitzgerald, SM, Qian, HZ, Kraus, VB, Sereny, M, Hu, P, Yin, ZX, Xu, JW, and Zeng, Y. "High sensitivity C-reactive protein associated with different health predictors in middle-aged and oldest old Chinese." Biomedical and Environmental Sciences 25, no. 3 (2012): 257-266. Full Text
  - Huffman, KM, Pieper, CF, Kraus, VB, Kraus, WE, Fillenbaum, GG, and Cohen, HJ. "Relations of a marker of endothelial activation (s-VCAM) to function and mortality in community-dwelling older adults." J Gerontol A Biol Sci Med Sci 66, no. 12 (December 2011): 1369-1375. Full Text Link to Item
  - Allen, KD, Mata, BA, Gabr, MA, Huebner, JL, Kraus, VB, and Setton, LA. "GAIT COMPENSATIONS IN A RAT MEDIAL MENISCUS TRANSECTION MODEL OF OSTEOARTHRITIS." OSTEOARTHRITIS AND CARTILAGE 19 (September 2011): S88-S89. Link to Item
  - Catterall, J, Hsueh, M-F, Stabler, TV, Renner, JM, Jordan, JM, and Kraus, VB. "A UNIQUE DEAMIDATED CARTILAGE OLIGOMERIC MATRIX PROTEIN (COMP) BIOMARKER PREFERENTIALLY IDENTIFIES HIP OSTEOARTHRITIS." OSTEOARTHRITIS AND CARTILAGE 19 (September 2011): S72-S72. Link to Item
  - Diekman, BO, Wu, C-L, Louer, CS, Furman, BD, Huebner, JL, Kraus, VB, Olson, SA, and Guilak, F. "INTRA-ARTICULAR INJECTION OF PURIFIED MESENCHYMAL STEM CELLS FROM C57BL/6 OR MRL/MPJ "SUPERHEALER" MICE PREVENTS POSTTRAUMATIC ARTHRITIS." OSTEOARTHRITIS AND CARTILAGE 19 (September 2011): S5-S5. Link to Item
  - Taylor, AM, Hsueh, M-F, Ranganath, LR, Gallagher, JA, Catterall, JB, and Kraus, VB. "ANALYSIS OF CARTILAGE BIOMARKERS OF TURNOVER AND AGING IN THE OSTEOARTHROPATHY OF ALKAPTONURIA." OSTEOARTHRITIS AND CARTILAGE 19 (September 2011): S80-S80. Link to Item
  - Eckstein, F, Le Graverand, MPH, Charles, HC, Hunter, DJ, Kraus, VB, Sunyer, T, Nemirovskyi, O, Wyman, BT, Buck, R, A9001140, and investigators, . "Clinical, radiographic, molecular and MRI-based predictors of cartilage loss in knee osteoarthritis." Ann Rheum Dis 70, no. 7 (July 2011): 1223-1230. Full Text Link to Item
  - Lewis, JS, Hembree, WC, Furman, BD, Tippets, L, Cattel, D, Huebner, JL, Little, D, DeFrate, LE, Kraus, VB, Guilak, F, and Olson, SA. "Acute joint pathology and synovial inflammation is associated with increased intra-articular fracture severity in the mouse knee." Osteoarthritis Cartilage 19, no. 7 (July 2011): 864-873. Full Text Link to Item
  - McDaniel, G, Renner, JB, Sloane, R, and Kraus, VB. "Association of knee and ankle osteoarthritis with physical performance." Osteoarthritis Cartilage 19, no. 6 (June 2011): 634-638. Full Text Link to Item
  - Lum, H, Sloane, R, Huffman, KM, Kraus, VB, Thompson, DK, Kraus, WE, Bain, JR, Stevens, R, Pieper, CF, Taylor, GA, Newgard, CB, Cohen, HJ, and Morey, MC. "Plasma acylcarnitines are associated with physical performance in elderly men." J Gerontol A Biol Sci Med Sci 66, no. 5 (May 2011): 548-553. Full Text Link to Item
  - Kraus, VB. "Osteoarthritis year 2010 in review: biochemical markers." Osteoarthritis Cartilage 19, no. 4 (April 2011): 346-353. (Review) Full Text Link to Item
  - Allen, KD, Jordan, JM, Doherty, M, Renner, JB, and Kraus, VB. "Performance of global assessments of hip, knee, and back symptom change." Clin Rheumatol 30, no. 3 (March 2011): 331-338. Full Text Link to Item
  - Kraus, VB, Burnett, B, Coindreau, J, Cottrell, S, Eyre, D, Gendreau, M, Gardiner, J, Garnero, P, Hardin, J, Henrotin, Y, Heinegård, D, Ko, A, Lohmander, LS, Matthews, G, Menetski, J, Moskowitz, R, Persiani, S, Poole, AR, Rousseau, JC, Todman, M, and Group, OARSIFDAOBW. "Application of biomarkers in the development of drugs intended for the treatment of osteoarthritis." Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society (March 2011). (Academic Article) Full Text
  - Denoble, AE, Huffman, KM, Stabler, TV, Kelly, SJ, Hershfield, MS, McDaniel, GE, Coleman, RE, and Kraus, VB. "Uric acid is a danger signal of increasing risk for osteoarthritis through inflammasome activation." Proc Natl Acad Sci U S A 108, no. 5 (February 1, 2011): 2088-2093. Full Text Link to Item
  - Redman, LM, Huffman, KM, Landerman, LR, Pieper, CF, Bain, JR, Muehlbauer, MJ, Stevens, RD, Wenner, BR, Kraus, VB, Newgard, CB, Kraus, WE, and Ravussin, E. "Effect of caloric restriction with and without exercise on metabolic intermediates in nonobese men and women." J Clin Endocrinol Metab 96, no. 2 (February 2011): E312-E321. Full Text Link to Item
  - Attur, M, Belitskaya-Lévy, I, Oh, C, Krasnokutsky, S, Greenberg, J, Samuels, J, Smiles, S, Lee, S, Patel, J, Al-Mussawir, H, McDaniel, G, Kraus, VB, and Abramson, SB. "Increased interleukin-1β gene expression in peripheral blood leukocytes is associated with increased pain and predicts risk for progression of symptomatic knee osteoarthritis." Arthritis and Rheumatism 63, no. 7 (2011): 1908-1917. Full Text
  - Cheng, AWM, Stabler, TV, Bolognesi, M, and Kraus, VB. "Selenomethionine inhibits IL-1β inducible nitric oxide synthase (iNOS) and cyclooxygenase 2 (COX2) expression in primary human chondrocytes." Osteoarthritis Cartilage 19, no. 1 (January 2011): 118-125. Full Text Link to Item
  - Golightly, YM, Marshall, SW, Kraus, VB, Renner, JB, Villaveces, A, Casteel, C, and Jordan, JM. "Biomarkers of incident radiographic knee osteoarthritis: Do they vary by chronic knee symptoms?." Arthritis and Rheumatism 63, no. 8 (2011): 2276-2283. Full Text
  - Huffman, KM, Slentz, CA, Bateman, LA, Thompson, D, Muehlbauer, MJ, Bain, JR, Stevens, RD, Wenner, BR, Kraus, VB, Newgard, CB, and Kraus, WE. "Exercise-induced changes in metabolic intermediates, hormones, and inflammatory markers associated with improvements in insulin sensitivity." Diabetes Care 34, no. 1 (January 2011): 174-176. Full Text Open Access Copy Link to Item
  - Meulenbelt, I, Kraus, VB, Sandell, LJ, and Loughlin, J. "Summary of the oa biomarkers workshop 2010 - genetics and genomics: New targets in oa." Osteoarthritis and Cartilage 19, no. 9 (2011): 1091-1094. Full Text
  - Nelson, AE, Chaudhary, S, Kraus, VB, Fang, F, Chen, J-C, Schwartz, TA, Shi, XA, Renner, JB, Stabler, TV, Helmick, CG, Caldwell, K, Poole, AR, and Jordan, JM. "Whole blood lead levels are associated with biomarkers of joint tissue metabolism in African American and white men and women: The Johnston County Osteoarthritis Project." Environmental Research 111, no. 8 (2011): 1208-1214. Full Text
  - Nelson, AE, DeVellis, RF, Renner, JB, Schwartz, TA, Conaghan, PG, Kraus, VB, and Jordan, JM. "Quantification of the whole-body burden of radiographic osteoarthritis using factor analysis." Arthritis Research and Therapy 13, no. 5 (2011). Full Text Open Access Copy
  - Nelson, AE, Renner, JB, Schwartz, TA, Kraus, VB, Helmick, CG, and Jordan, JM. "Differences in multijoint radiographic osteoarthritis phenotypes among African Americans and Caucasians: The Johnston County Osteoarthritis project." Arthritis and Rheumatism 63, no. 12 (2011): 3843-3852. Full Text
  - Redman, LM, Huffman, KM, Landerman, LR, Pieper, CF, Bain, JR, Muehlbauer, MJ, Stevens, RD, Wenner, BR, Kraus, VB, Newgard, CB, Kraus, WE, and Ravussin, E. "Effect of Caloric Restriction with and without Exercise on Metabolic Intermediates in Nonobese Men and Women." Endocrinology 152, no. 1 (January 2011): 332-333. Full Text
  - Schmitz, N, Laverty, S, Kraus, VB, and Aigner, T. "Response to Letter to the Editor: 'India ink and cartilage'." Osteoarthritis and Cartilage 19, no. 3 (2011): 333-335. Full Text
  - Denoble, AE, Hall, N, Pieper, CF, and Kraus, VB. "Patellar skin surface temperature by thermography reflects knee osteoarthritis severity. (Published online)" Clin Med Insights Arthritis Musculoskelet Disord 3 (October 15, 2010): 69-75. Full Text Open Access Copy Link to Item
  - Aigner, T, Cook, JL, Gerwin, N, Glasson, SS, Laverty, S, Little, CB, McIlwraith, W, and Kraus, VB. "Histopathology atlas of animal model systems - overview of guiding principles." Osteoarthritis Cartilage 18 Suppl 3 (October 2010): S2-S6. Full Text Link to Item
  - Huffman, KM, Redman, LM, Landerman, LR, Pieper, CF, Bain, JB, Kraus, VB, Newgard, CB, and Ravussin, E. "CALORIC RESTRICTION AND IMPROVEMENTS IN METABOLIC FLEXIBILITY." GERONTOLOGIST 50 (October 2010): 349-349. Link to Item
  - Kraus, VB, Huebner, JL, DeGroot, J, and Bendele, A. "The OARSI histopathology initiative - recommendations for histological assessments of osteoarthritis in the guinea pig." Osteoarthritis Cartilage 18 Suppl 3 (October 2010): S35-S52. Full Text Link to Item
  - Landerman, LR, Pieper, CF, Huffman, KM, Morey, MC, Kraus, WE, Cohen, H, and Kraus, VB. "ASSESSMENT OF THE RELATIONSHIP OF CYTOKINES WITH AGE, BMI, GENDER AND RACE: A META-ANALYSIS OF THE DUKE PEPPER STUDIES." GERONTOLOGIST 50 (October 2010): 349-350. Link to Item
  - Schmitz, N, Laverty, S, Kraus, VB, and Aigner, T. "Basic methods in histopathology of joint tissues." Osteoarthritis Cartilage 18 Suppl 3 (October 2010): S113-S116. (Review) Full Text Link to Item
  - Sloane, R, Kraus, VB, and Thompson, D. "THE RELATIONSHIP BETWEEN ACYLCARNATINES AND PHYSICAL PERFORMANCE IN OSTEOARTHRITIS." GERONTOLOGIST 50 (October 2010): 349-349. Link to Item
  - Thompson, D, Kraus, VB, and Sloane, R. "THE RELATIONSHIP OF CYTOKINES WITH PHYSICAL PERFORMANCE: THE POP STUDY." GERONTOLOGIST 50 (October 2010): 349-349. Link to Item
  - Chuckpaiwong, B, Charles, HC, Kraus, VB, Guilak, F, and Nunley, JA. "Age-associated increases in the size of the infrapatellar fat pad in knee osteoarthritis as measured by 3T MRI." Journal of orthopaedic research : official publication of the Orthopaedic Research Society 28, no. 9 (September 2010): 1149-1154. Full Text
  - Kempta Lekpa, F, Piette, JC, Bastuji-Garin, S, Kraus, VB, Stabler, TV, Poole, AR, Marini-Portugal, A, and Chevalier, X. "Serum cartilage oligomeric matrix protein (COMP) level is a marker of disease activity in relapsing polychondritis." Clin Exp Rheumatol 28, no. 4 (July 2010): 553-555. Link to Item
  - Kraus, VB, Nevitt, M, and Sandell, LJ. "Summary of the OA biomarkers workshop 2009--biochemical biomarkers: biology, validation, and clinical studies." Osteoarthritis Cartilage 18, no. 6 (June 2010): 742-745. Full Text Link to Item
  - Nelson, AE, Golightly, YM, Kraus, VB, Stabler, T, Renner, JB, Helmick, CG, and Jordan, JM. "Serum transforming growth factor-beta 1 is not a robust biomarker of incident and progressive radiographic osteoarthritis at the hip and knee: the Johnston County Osteoarthritis Project." Osteoarthritis Cartilage 18, no. 6 (June 2010): 825-829. Full Text Link to Item
  - Attur, M, Wang, H-Y, Kraus, VB, Bukowski, JF, Aziz, N, Krasnokutsky, S, Samuels, J, Greenberg, J, McDaniel, G, Abramson, SB, and Kornman, KS. "Radiographic severity of knee osteoarthritis is conditional on interleukin 1 receptor antagonist gene variations." Ann Rheum Dis 69, no. 5 (May 2010): 856-861. Full Text Open Access Copy Link to Item
  - Kraus, VB. "Waiting for action on the osteoarthritis front." Curr Drug Targets 11, no. 5 (May 2010): 518-520. Link to Item
  - Schmitz, N, Kraus, VB, and Aigner, T. "Targets to tackle--the pathophysiology of the disease." Curr Drug Targets 11, no. 5 (May 2010): 521-527. Link to Item
  - Kraus, VB, Kepler, TB, Stabler, T, Renner, J, and Jordan, J. "First qualification study of serum biomarkers as indicators of total body burden of osteoarthritis. (Published online)" PLoS One 5, no. 3 (March 17, 2010): e9739-. Full Text Open Access Copy Link to Item
  - Chen, H-C, Kraus, VB, Li, Y-J, Nelson, S, Haynes, C, Johnson, J, Stabler, T, Hauser, ER, Gregory, SG, Kraus, WE, and Shah, SH. "Genome-wide linkage analysis of quantitative biomarker traits of osteoarthritis in a large, multigenerational extended family." Arthritis Rheum 62, no. 3 (March 2010): 781-790. Full Text Link to Item
  - Huebner, JL, Williams, JM, Deberg, M, Henrotin, Y, and Kraus, VB. "Collagen fibril disruption occurs early in primary guinea pig knee osteoarthritis." Osteoarthritis Cartilage 18, no. 3 (March 2010): 397-405. Full Text Link to Item
  - McDaniel, G, Mitchell, KL, Charles, C, and Kraus, VB. "A comparison of five approaches to measurement of anatomic knee alignment from radiographs." Osteoarthritis Cartilage 18, no. 2 (February 2010): 273-277. Full Text Link to Item
  - Catterall, JB, Stabler, TV, Flannery, CR, and Kraus, VB. "Changes in serum and synovial fluid biomarkers after acute injury (NCT00332254)." Arthritis Res Ther 12, no. 6 (2010): R229-. Full Text Open Access Copy Link to Item
  - Griffin, TM, Fermor, B, Huebner, JL, Kraus, VB, Rodriguiz, RM, Wetsel, WC, Cao, L, Setton, LA, and Guilak, F. "Diet-induced obesity differentially regulates behavioral, biomechanical, and molecular risk factors for osteoarthritis in mice." Arthritis Res Ther 12, no. 4 (2010): R130-. Full Text Open Access Copy Link to Item
  - Hudelmaier, M, Wirth, W, Wehr, B, Kraus, V, Wyman, BT, Graverand, M-PHL, and Eckstein, F. "Femorotibial cartilage morphology: Reproducibility of different metrics and femoral regions, and sensitivity to change in disease." Cells Tissues Organs 192, no. 5 (2010): 340-350. Full Text
  - Hunter, DJ, Losina, E, Guermazi, A, Burstein, D, Lassere, MN, and Kraus, V. "A pathway and approach to biomarker validation and qualification for osteoarthritis clinical trials." Current Drug Targets 11, no. 5 (2010): 536-545. Full Text
  - Le Graverand, M-PH, Buck, RJ, Wyman, BT, Vignon, E, Mazzuca, SA, Brandt, KD, Piperno, M, Charles, HC, Hudelmaier, M, Hunter, DJ, Jackson, C, Kraus, VB, Link, TM, Majumdar, S, Prasad, PV, Schnitzer, TJ, Vaz, A, Wirth, W, and Eckstein, F. "Change in regional cartilage morphology and joint space width in osteoarthritis participants versus healthy controls: a multicentre study using 3.0 Tesla MRI and Lyon-Schuss radiography." Ann Rheum Dis 69, no. 1 (January 2010): 155-162. Full Text Link to Item
  - Lotz, MK, and Kraus, VB. "Correction: Posttraumatic osteoarthritis: Pathogenesis and pharmacological treatment options." Arthritis Research and Therapy 12, no. 6 (2010). Full Text
  - Kraus, VB, Feng, S, Wang, S, White, S, Ainslie, M, Brett, A, Holmes, A, and Charles, HC. "Trabecular morphometry by fractal signature analysis is a novel marker of osteoarthritis progression." Arthritis Rheum 60, no. 12 (December 2009): 3711-3722. Full Text Link to Item
  - Sims, EL, Keefe, FJ, Kraus, VB, Guilak, F, Queen, RM, and Schmitt, D. "Racial differences in gait mechanics associated with knee osteoarthritis." Aging Clin Exp Res 21, no. 6 (December 2009): 463-469. Link to Item
  - Addison, S, Coleman, RE, Feng, S, McDaniel, G, and Kraus, VB. "Whole-body bone scintigraphy provides a measure of the total-body burden of osteoarthritis for the purpose of systemic biomarker validation." Arthritis Rheum 60, no. 11 (November 2009): 3366-3373. Full Text Link to Item
  - Kraus, VB, McDaniel, G, Worrell, TW, Feng, S, Vail, TP, Varju, G, and Coleman, RE. "Association of bone scintigraphic abnormalities with knee malalignment and pain." Ann Rheum Dis 68, no. 11 (November 2009): 1673-1679. Full Text Link to Item
  - Nebel, MB, Sims, EL, Keefe, FJ, Kraus, VB, Guilak, F, Caldwell, DS, Pells, JJ, Queen, R, and Schmitt, D. "The relationship of self-reported pain and functional impairment to gait mechanics in overweight and obese persons with knee osteoarthritis." Arch Phys Med Rehabil 90, no. 11 (November 2009): 1874-1879. Full Text Link to Item
  - Griffin, TM, Huebner, JL, Kraus, VB, and Guilak, F. "Extreme obesity due to impaired leptin signaling in mice does not cause knee osteoarthritis." Arthritis Rheum 60, no. 10 (October 2009): 2935-2944. Full Text Link to Item
  - Allen, KD, Griffin, TM, Rodriguiz, RM, Wetsel, WC, Kraus, VB, Huebner, JL, Boyd, LM, and Setton, LA. "Decreased physical function and increased pain sensitivity in mice deficient for type IX collagen." Arthritis Rheum 60, no. 9 (September 2009): 2684-2693. Full Text Link to Item
  - Hellio Le Graverand, M-P, Buck, RJ, Wyman, BT, Vignon, E, Mazzuca, SA, Brandt, KD, Piperno, M, Charles, HC, Hudelmaier, M, Hunter, DJ, Jackson, C, Kraus, VB, Link, TM, Majumdar, S, Prasad, PV, Schnitzer, TJ, Vaz, A, Wirth, W, and Eckstein, F. "Subregional femorotibial cartilage morphology in women--comparison between healthy controls and participants with different grades of radiographic knee osteoarthritis." Osteoarthritis Cartilage 17, no. 9 (September 2009): 1177-1185. Full Text Link to Item
  - Huebner, JL, Johnson, KA, Kraus, VB, and Terkeltaub, RA. "Transglutaminase 2 is a marker of chondrocyte hypertrophy and osteoarthritis severity in the Hartley guinea pig model of knee OA." Osteoarthritis Cartilage 17, no. 8 (August 2009): 1056-1064. Full Text Link to Item
  - Maksymowych, WP, Fitzgerald, O, Wells, GA, Gladman, DD, Landewé, R, Ostergaard, M, Taylor, WJ, Christensen, R, Tak, P-P, Boers, M, Syversen, SW, Bathon, JM, Ritchlin, CJ, Mease, PJ, Bykerk, VP, Garnero, P, Geusens, P, El-Gabalawy, H, Aletaha, D, Inman, RD, Kraus, VB, Kvien, TK, and van der Heijde, D. "Proposal for levels of evidence schema for validation of a soluble biomarker reflecting damage endpoints in rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis, and recommendations for study design." J Rheumatol 36, no. 8 (August 2009): 1792-1799. Full Text Link to Item
  - Maksymowych, WP, Landewé, R, Tak, P-P, Ritchlin, CJ, Ostergaard, M, Mease, PJ, El-Gabalawy, H, Garnero, P, Gladman, DD, Fitzgerald, O, Aletaha, D, Bykerk, VP, Bathon, JM, Syversen, SW, Boers, M, Geusens, P, Inman, RD, Kraus, VB, Kvien, TK, Taylor, WJ, Wells, GA, and van der Heijde, D. "Reappraisal of OMERACT 8 draft validation criteria for a soluble biomarker reflecting structural damage endpoints in rheumatoid arthritis, psoriatic arthritis, and spondyloarthritis: the OMERACT 9 v2 criteria." J Rheumatol 36, no. 8 (August 2009): 1785-1791. Full Text Link to Item
  - Nelson, AE, Fang, F, Shi, XA, Kraus, VB, Stabler, T, Renner, JB, Schwartz, TA, Helmick, CG, and Jordan, JM. "Failure of serum transforming growth factor-beta (TGF-beta1) as a biomarker of radiographic osteoarthritis at the knee and hip: a cross-sectional analysis in the Johnston County Osteoarthritis Project." Osteoarthritis Cartilage 17, no. 6 (June 2009): 772-776. Full Text Link to Item
  - Cibere, J, Zhang, H, Garnero, P, Poole, AR, Lobanok, T, Saxne, T, Kraus, VB, Way, A, Thorne, A, Wong, H, Singer, J, Kopec, J, Guermazi, A, Peterfy, C, Nicolaou, S, Munk, PL, and Esdaile, JM. "Association of biomarkers with pre-radiographically defined and radiographically defined knee osteoarthritis in a population-based study." Arthritis Rheum 60, no. 5 (May 2009): 1372-1380. Full Text Link to Item
  - Somers, TJ, Keefe, FJ, Pells, JJ, Dixon, KE, Waters, SJ, Riordan, PA, Blumenthal, JA, McKee, DC, LaCaille, L, Tucker, JM, Schmitt, D, Caldwell, DS, Kraus, VB, Sims, EL, Shelby, RA, and Rice, JR. "Pain catastrophizing and pain-related fear in osteoarthritis patients: relationships to pain and disability." J Pain Symptom Manage 37, no. 5 (May 2009): 863-872. Full Text Link to Item
  - Shamji, MF, Allen, KD, So, S, Jing, L, Adams, SB, Schuh, R, Huebner, J, Kraus, VB, Friedman, AH, Setton, LA, and Richardson, WJ. "Gait abnormalities and inflammatory cytokines in an autologous nucleus pulposus model of radiculopathy." Spine (Phila Pa 1976) 34, no. 7 (April 1, 2009): 648-654. Full Text Link to Item
  - Kraus, VB. "Biomarkers and biomarker patterns: new and emerging trends to distinguish osteoarthritis disease subsets and progression." INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY 90, no. 1 (February 2009): A45-A46. Link to Item
  - Catterall, JB, Barr, D, Bolognesi, M, Zura, RD, and Kraus, VB. "Post-translational aging of proteins in osteoarthritic cartilage and synovial fluid as measured by isomerized aspartate." Arthritis Res Ther 11, no. 2 (2009): R55-. Full Text Open Access Copy Link to Item
  - Couchman, J, Kraus, V, Boyde, A, Baker, N, Barr, E, Lohmander, S, Salter, D, Poulet, B, Webster, R, Vincent, T, Loughlin, J, Silman, A, Blain, E, Saklatvala, J, Ngee, HL, Didangelos, A, Garvican, E, Nagase, H, Kadler, K, Scott, J, Marson, A, Huxley-Jones, J, Hunziker, E, Williams, J, Edwards, G, Wann, A, Harrison, R, Tuan, R, Kraan, PVD, Troeberg, L, Curtin, C, Roberts, H, and Flannery, C. "Past, present and future insights into the understanding and treatment of osteoarthritis: Molecular and mechanical approaches." International Journal of Experimental Pathology 90, no. 1 (2009): A30-A84. Full Text
  - Sims, EL, Carland, JM, Keefe, FJ, Kraus, VB, Guilak, F, and Schmitt, D. "Sex differences in biomechanics associated with knee osteoarthritis." J Women Aging 21, no. 3 (2009): 159-170. Full Text Link to Item
  - Stabler, TV, Byers, SS, Zura, RD, and Kraus, VB. "Amino acid racemization reveals differential protein turnover in osteoarthritic articular and meniscal cartilages." Arthritis Res Ther 11, no. 2 (2009): R34-. Full Text Open Access Copy Link to Item
  - Syversen, SW, Landewe, R, Heijde, DVD, Bathon, JM, Boers, M, Bykerk, VP, Fitzgerald, O, Gladman, DD, Garnero, P, Geusens, P, El-Gabalawy, H, Inman, RD, Kraus, V, Kvien, TK, Mease, PJ, Østergaard, M, Ritchlin, CJ, Tak, P-P, Taylor, WJ, and Maksymowych, WP. "Testing of the OMERACT 8 draft validation criteria for a soluble biomarker reflecting structural damage in rheumatoid arthritis: A systematic literature search on 5 candidate biomarkers." Journal of Rheumatology 36, no. 8 (2009): 1769-1784. Full Text
  - Chen, H-C, Shah, SH, Li, Y-J, Stabler, TV, Jordan, JM, and Kraus, VB. "Inverse association of general joint hypermobility with hand and knee osteoarthritis and serum cartilage oligomeric matrix protein levels." Arthritis Rheum 58, no. 12 (December 2008): 3854-3864. Full Text Link to Item
  - Eckstein, F, Buck, RJ, Burstein, D, Charles, HC, Crim, J, Hudelmaier, M, Hunter, DJ, Hutchins, G, Jackson, C, Kraus, VB, Lane, NE, Link, TM, Majumdar, LS, Mazzuca, S, Prasad, PV, Schnitzer, TJ, Taljanovic, MS, Vaz, A, Wyman, B, Le Graverand, M-PH, and A9001140 Study Group, . "Precision of 3.0 Tesla quantitative magnetic resonance imaging of cartilage morphology in a multicentre clinical trial." Ann Rheum Dis 67, no. 12 (December 2008): 1683-1688. Full Text Link to Item
  - Gordon, CD, Stabler, TV, and Kraus, VB. "Variation in osteoarthritis biomarkers from activity not food consumption." Clin Chim Acta 398, no. 1-2 (December 2008): 21-26. Full Text Link to Item
  - Mazzuca, SA, Hellio Le Graverand, M-P, Vignon, E, Hunter, DJ, Jackson, CG, Kraus, VB, Link, TM, Schnitzer, TJ, Vaz, A, and Charles, HC. "Performance of a non-fluoroscopically assisted substitute for the Lyon schuss knee radiograph: quality and reproducibility of positioning and sensitivity to joint space narrowing in osteoarthritic knees." Osteoarthritis Cartilage 16, no. 12 (December 2008): 1555-1559. Full Text Link to Item
  - Seifer, DR, Furman, BD, Guilak, F, Olson, SA, Brooks, SC, and Kraus, VB. "Novel synovial fluid recovery method allows for quantification of a marker of arthritis in mice." Osteoarthritis Cartilage 16, no. 12 (December 2008): 1532-1538. Full Text Link to Item
  - Le Graverand, M-PH, Vignon, EP, Brandt, KD, Mazzuca, SA, Piperno, M, Buck, R, Charles, HC, Hunter, DJ, Jackson, CG, Kraus, VB, Link, TM, Schnitzer, TJ, Vaz, A, and Wyman, B. "Head-to-head comparison of the Lyon Schuss and fixed flexion radiographic techniques. Long-term reproducibility in normal knees and sensitivity to change in osteoarthritic knees." Ann Rheum Dis 67, no. 11 (November 2008): 1562-1566. Full Text Link to Item
  - Atif, U, Philip, A, Aponte, J, Woldu, EM, Brady, S, Kraus, VB, Jordan, JM, Doherty, M, Wilson, AG, Moskowitz, RW, Hochberg, M, Loeser, R, Renner, JB, and Chiano, M. "Absence of association of asporin polymorphisms and osteoarthritis susceptibility in US Caucasians." Osteoarthritis Cartilage 16, no. 10 (October 2008): 1174-1177. Full Text Link to Item
  - Quintana, DJ, Garnero, P, Huebner, JL, Charni-Ben Tabassi, N, and Kraus, VB. "PIIANP and HELIXII diurnal variation." Osteoarthritis Cartilage 16, no. 10 (October 2008): 1192-1195. Full Text Link to Item
  - Chen, H-C, Shah, S, Stabler, TV, Li, Y-J, and Kraus, VB. "Biomarkers associated with clinical phenotypes of hand osteoarthritis in a large multigenerational family: the CARRIAGE family study." Osteoarthritis Cartilage 16, no. 9 (September 2008): 1054-1059. Full Text Link to Item
  - Pells, JJ, Shelby, RA, Keefe, FJ, Dixon, KE, Blumenthal, JA, Lacaille, L, Tucker, JM, Schmitt, D, Caldwell, DS, and Kraus, VB. "Arthritis self-efficacy and self-efficacy for resisting eating: relationships to pain, disability, and eating behavior in overweight and obese individuals with osteoarthritic knee pain." Pain 136, no. 3 (June 2008): 340-347. Full Text Link to Item
  - Ward, BD, Furman, BD, Huebner, JL, Kraus, VB, Guilak, F, and Olson, SA. "Absence of posttraumatic arthritis following intraarticular fracture in the MRL/MpJ mouse." Arthritis Rheum 58, no. 3 (March 2008): 744-753. Full Text Link to Item
  - Elliott, AL, Kraus, VB, Fang, F, Renner, JB, Schwartz, TA, Salazar, A, Huguenin, T, Hochberg, MC, Helmick, CG, and Jordan, JM. "Joint-specific hand symptoms and self-reported and performance-based functional status in African Americans and Caucasians: The Johnston County Osteoarthritis Project." Ann Rheum Dis 66, no. 12 (December 2007): 1622-1626. Full Text Link to Item
  - Charles, HC, Kraus, VB, Ainslie, M, and Hellio Le Graverand-Gastineau, M-P. "Optimization of the fixed-flexion knee radiograph." Osteoarthritis Cartilage 15, no. 11 (November 2007): 1221-1224. Full Text Link to Item
  - Shamji, MF, Betre, H, Kraus, VB, Chen, J, Chilkoti, A, Pichika, R, Masuda, K, and Setton, LA. "Development and characterization of a fusion protein between thermally responsive elastin-like polypeptide and interleukin-1 receptor antagonist: sustained release of a local antiinflammatory therapeutic." Arthritis Rheum 56, no. 11 (November 2007): 3650-3661. Full Text Link to Item
  - Kraus, VB, Stabler, TV, Kong, SY, Varju, G, and McDaniel, G. "Measurement of synovial fluid volume using urea." Osteoarthritis Cartilage 15, no. 10 (October 2007): 1217-1220. Full Text Link to Item
  - Kraus, VB, Stabler, TV, Luta, G, Renner, JB, Dragomir, AD, and Jordan, JM. "Interpretation of serum C-reactive protein (CRP) levels for cardiovascular disease risk is complicated by race, pulmonary disease, body mass index, gender, and osteoarthritis." Osteoarthritis Cartilage 15, no. 8 (August 2007): 966-971. Full Text Link to Item
  - Allen, KD, DeVellis, RF, Renner, JB, Kraus, VB, and Jordan, JM. "Validity and factor structure of the AUSCAN Osteoarthritis Hand Index in a community-based sample." Osteoarthritis Cartilage 15, no. 7 (July 2007): 830-836. Full Text Link to Item
  - Huebner, JL, Seifer, DR, and Kraus, VB. "A longitudinal analysis of serum cytokines in the Hartley guinea pig model of osteoarthritis." Osteoarthritis Cartilage 15, no. 3 (March 2007): 354-356. Full Text Link to Item
  - Huffman, KM, Bowers, JR, Dailiana, Z, Huebner, JL, Urbaniak, JR, and Kraus, VB. "Synovial fluid metabolites in osteonecrosis." Rheumatology (Oxford) 46, no. 3 (March 2007): 523-528. Full Text Link to Item
  - Keeling, SO, Landewe, R, van der Heijde, D, Bathon, J, Boers, M, Garnero, P, Geusens, P, El-Gabalawy, H, Inman, RD, Kraus, VB, Kvien, TK, Mease, PJ, Ostergaard, M, Ritchlin, C, Syversen, SW, and Maksymowych, WP. "Testing of the preliminary OMERACT validation criteria for a biomarker to be regarded as reflecting structural damage endpoints in rheumatoid arthritis clinical trials: the example of C-reactive protein." J Rheumatol 34, no. 3 (March 2007): 623-633. (Review) Link to Item
  - Maksymowych, WP, Landewe, R, Boers, M, Garnero, P, Geusens, P, El-Gabalawy, H, Heinegard, D, Kraus, VB, Lohmander, S, Matyas, J, Saxne, T, and van der Heijde, D. "Development of draft validation criteria for a soluble biomarker to be regarded as a valid biomarker reflecting structural damage endpoints in rheumatoid arthritis and spondyloarthritis clinical trials." J Rheumatol 34, no. 3 (March 2007): 634-640. Link to Item
  - Birmingham, JD, Vilim, V, and Kraus, VB. "Collagen biomarkers for arthritis applications. (Published online)" Biomark Insights 1 (February 7, 2007): 61-76. Open Access Copy Link to Item
  - Kraus, VB, and Jordan, JM. "Serum C-Reactive Protein (CRP), Target for Therapy or Trouble? (Published online)." Biomark Insights 1 (February 7, 2007): 77-80. Open Access Copy Link to Item
  - Kraus, VB, Jordan, JM, Doherty, M, Wilson, AG, Moskowitz, R, Hochberg, M, Loeser, R, Hooper, M, Renner, JB, Crane, MM, Hastie, P, Sundseth, S, and Atif, U. "The Genetics of Generalized Osteoarthritis (GOGO) study: study design and evaluation of osteoarthritis phenotypes." Osteoarthritis Cartilage 15, no. 2 (February 2007): 120-127. Full Text Link to Item
  - Henrotin, Y, Addison, S, Kraus, V, and Deberg, M. "Type II collagen markers in osteoarthritis: What do they indicate?." Current Opinion in Rheumatology 19, no. 5 (2007): 444-450. Full Text
  - Huebner, JL, Seifer, DR, and Kraus, VB. "Erratum to "A longitudinal analysis of serum cytokines in the Hartley guinea pig model of osteoarthritis" [Osteoarthritis Cartilage 15 (2007) 354-356] (DOI:10.1016/j.joca.2006.10.014)." Osteoarthritis and Cartilage 15, no. 7 (2007): 848--. Full Text
  - Kraus, VB. "Response to letter: Static knee alignment and its association with radiographic knee osteoarthritis." Osteoarthritis and Cartilage 15, no. 7 (2007): 846-847. Full Text
  - Allen, KD, Jordan, JM, Renner, JB, and Kraus, VB. "Relationship of global assessment of change to AUSCAN and pinch and grip strength among individuals with hand osteoarthritis." Osteoarthritis Cartilage 14, no. 12 (December 2006): 1281-1287. Full Text Link to Item
  - McCudden, CR, and Kraus, VB. "Biochemistry of amino acid racemization and clinical application to musculoskeletal disease." Clin Biochem 39, no. 12 (December 2006): 1112-1130. (Review) Full Text Link to Item
  - Betre, H, Liu, W, Zalutsky, MR, Chilkoti, A, Kraus, VB, and Setton, LA. "A thermally responsive biopolymer for intra-articular drug delivery." J Control Release 115, no. 2 (October 10, 2006): 175-182. Full Text Link to Item
  - Huebner, JL, and Kraus, VB. "Assessment of the utility of biomarkers of osteoarthritis in the guinea pig." Osteoarthritis Cartilage 14, no. 9 (September 2006): 923-930. Full Text Link to Item
  - Bauer, DC, Hunter, DJ, Abramson, SB, Attur, M, Corr, M, Felson, D, Heinegård, D, Jordan, JM, Kepler, TB, Lane, NE, Saxne, T, Tyree, B, Kraus, VB, and Osteoarthritis Biomarkers Network, . "Classification of osteoarthritis biomarkers: a proposed approach." Osteoarthritis Cartilage 14, no. 8 (August 2006): 723-727. (Review) Full Text Link to Item
  - Kong, SY, Stabler, TV, Criscione, LG, Elliott, AL, Jordan, JM, and Kraus, VB. "Diurnal variation of serum and urine biomarkers in patients with radiographic knee osteoarthritis." Arthritis Rheum 54, no. 8 (August 2006): 2496-2504. Full Text Link to Item
  - Allen, KD, Jordan, JM, Renner, JB, and Kraus, VB. "Validity, factor structure, and clinical relevance of the AUSCAN Osteoarthritis Hand Index." Arthritis Rheum 54, no. 2 (February 2006): 551-556. Full Text Link to Item
  - Kraus, VB. "Do biochemical markers have a role in osteoarthritis diagnosis and treatment?." Best Pract Res Clin Rheumatol 20, no. 1 (February 2006): 69-80. (Review) Full Text Link to Item
  - Piscoya, JL, Fermor, B, Kraus, VB, Stabler, TV, and Guilak, F. "The influence of mechanical compression on the induction of osteoarthritis-related biomarkers in articular cartilage explants." Osteoarthritis Cartilage 13, no. 12 (December 2005): 1092-1099. Full Text Link to Item
  - Eckstein, F, Charles, HC, Buck, RJ, Kraus, VB, Remmers, AE, Hudelmaier, M, Wirth, W, and Evelhoch, JL. "Accuracy and precision of quantitative assessment of cartilage morphology by magnetic resonance imaging at 3.0T." Arthritis Rheum 52, no. 10 (October 2005): 3132-3136. Full Text Link to Item
  - Criscione, LG, Elliott, AL, Stabler, T, Jordan, JM, Pieper, CF, and Kraus, VB. "Variation of serum hyaluronan with activity in individuals with knee osteoarthritis." Osteoarthritis Cartilage 13, no. 9 (September 2005): 837-840. Full Text Link to Item
  - Kraus, VB. "Biomarkers in osteoarthritis." Curr Opin Rheumatol 17, no. 5 (September 2005): 641-646. (Review) Link to Item
  - Lamers, RJAN, van Nesselrooij, JHJ, Kraus, VB, Jordan, JM, Renner, JB, Dragomir, AD, Luta, G, van der Greef, J, and DeGroot, J. "Identification of an urinary metabolite profile associated with osteoarthritis." Osteoarthritis Cartilage 13, no. 9 (September 2005): 762-768. Full Text Link to Item
  - McNulty, AL, Stabler, TV, Vail, TP, McDaniel, GE, and Kraus, VB. "Dehydroascorbate transport in human chondrocytes is regulated by hypoxia and is a physiologically relevant source of ascorbic acid in the joint." Arthritis and rheumatism 52, no. 9 (September 2005): 2676-2685. Full Text
  - Boyd, LM, Richardson, WJ, Chen, J, Kraus, VB, Tewari, A, and Setton, LA. "Osmolarity regulates gene expression in intervertebral disc cells determined by gene array and real-time quantitative RT-PCR." Ann Biomed Eng 33, no. 8 (August 2005): 1071-1077. Full Text Link to Item
  - Chang, J, Kauf, TL, Mahajan, S, Jordan, JM, Kraus, VB, Vail, TP, Reed, SD, Omar, MA, Kahler, KH, and Schulman, KA. "Impact of disease severity and gastrointestinal side effects on the health state preferences of patients with osteoarthritis." Arthritis Rheum 52, no. 8 (August 2005): 2366-2375. Full Text Link to Item
  - Kraus, VB, Vail, TP, Worrell, T, and McDaniel, G. "A comparative assessment of alignment angle of the knee by radiographic and physical examination methods." Arthritis Rheum 52, no. 6 (June 2005): 1730-1735. Full Text Link to Item
  - McNulty, AL, Vail, TP, and Kraus, VB. "Chondrocyte transport and concentration of ascorbic acid is mediated by SVCT2." Biochimica et biophysica acta 1712, no. 2 (June 2005): 212-221. Full Text
  - Dominick, KL, Jordan, JM, Renner, JB, and Kraus, VB. "Relationship of radiographic and clinical variables to pinch and grip strength among individuals with osteoarthritis." Arthritis Rheum 52, no. 5 (May 2005): 1424-1430. Full Text Link to Item
  - Elliott, AL, Kraus, VB, Luta, G, Stabler, T, Renner, JB, Woodard, J, Dragomir, AD, Helmick, CG, Hochberg, MC, and Jordan, JM. "Serum hyaluronan levels and radiographic knee and hip osteoarthritis in African Americans and Caucasians in the Johnston County Osteoarthritis Project." Arthritis Rheum 52, no. 1 (January 2005): 105-111. Full Text Link to Item
  - Stabler, T, Piette, J-C, Chevalier, X, Marini-Portugal, A, and Kraus, VB. "Serum cytokine profiles in relapsing polychondritis suggest monocyte/macrophage activation." Arthritis Rheum 50, no. 11 (November 2004): 3663-3667. Full Text Link to Item
  - Boyd, LM, Chen, J, Kraus, VB, and Setton, LA. "Conditioned medium differentially regulates matrix protein gene expression in cells of the intervertebral disc." Spine (Phila Pa 1976) 29, no. 20 (October 15, 2004): 2217-2222. Link to Item
  - Kraus, VB, Li, Y-J, Martin, ER, Jordan, JM, Renner, JB, Doherty, M, Wilson, AG, Moskowitz, R, Hochberg, M, Loeser, R, Hooper, M, and Sundseth, S. "Articular hypermobility is a protective factor for hand osteoarthritis." Arthritis Rheum 50, no. 7 (July 2004): 2178-2183. Full Text Link to Item
  - Varjú, G, Pieper, CF, Renner, JB, and Kraus, VB. "Assessment of hand osteoarthritis: correlation between thermographic and radiographic methods." Rheumatology (Oxford) 43, no. 7 (July 2004): 915-919. Full Text Link to Item
  - Guilak, F, Fermor, B, Keefe, FJ, Kraus, VB, Olson, SA, Pisetsky, DS, Setton, LA, and Weinberg, JB. "The role of biomechanics and inflammation in cartilage injury and repair." Clin Orthop Relat Res , no. 423 (June 2004): 17-26. (Review) Link to Item
  - Kraus, VB, Huebner, JL, Stabler, T, Flahiff, CM, Setton, LA, Fink, C, Vilim, V, and Clark, AG. "Ascorbic acid increases the severity of spontaneous knee osteoarthritis in a guinea pig model." Arthritis Rheum 50, no. 6 (June 2004): 1822-1831. Full Text Link to Item
  - Flahiff, CM, Kraus, VB, Huebner, JL, and Setton, LA. "Cartilage mechanics in the guinea pig model of osteoarthritis studied with an osmotic loading method." Osteoarthritis Cartilage 12, no. 5 (May 2004): 383-388. Full Text Link to Item
  - Jordan, JM, Kraus, VB, and Hochberg, MC. "Genetics of osteoarthritis." Curr Rheumatol Rep 6, no. 1 (February 2004): 7-13. (Review) Link to Item
  - Kraus, VB, Stabler, T, Le, ET, Saltarelli, M, and Allen, NB. "Urinary type II collagen neoepitope as an outcome measure for relapsing polychondritis." Arthritis Rheum 48, no. 10 (October 2003): 2942-2948. Full Text Link to Item
  - Stabler, TV, and Kraus, VB. "Ascorbic acid accumulates in cartilage in vivo." Clin Chim Acta 334, no. 1-2 (August 2003): 157-162. Link to Item
  - Kraus, VB. "Cyclooxygenase-2 inhibitors and nonsteroidal anti-inflammatory drugs in the management of arthritis." Foot Ankle Clin 8, no. 2 (June 2003): 187-vii. (Review) Link to Item
  - Lamers, R-JAN, DeGroot, J, Spies-Faber, EJ, Jellema, RH, Kraus, VB, Verzijl, N, TeKoppele, JM, Spijksma, GK, Vogels, JTWE, van der Greef, J, and van Nesselrooij, JHJ. "Identification of disease- and nutrient-related metabolic fingerprints in osteoarthritic Guinea pigs." J Nutr 133, no. 6 (June 2003): 1776-1780. Link to Item
  - Jordan, JM, Luta, G, Stabler, T, Renner, JB, Dragomir, AD, Vilim, V, Hochberg, MC, Helmick, CG, and Kraus, VB. "Ethnic and sex differences in serum levels of cartilage oligomeric matrix protein: the Johnston County Osteoarthritis Project." Arthritis Rheum 48, no. 3 (March 2003): 675-681. Full Text Link to Item
  - Vilím, V, Vobůrka, Z, Vytásek, R, Senolt, L, Tchetverikov, I, Kraus, VB, and Pavelka, K. "Monoclonal antibodies to human cartilage oligomeric matrix protein: epitope mapping and characterization of sandwich ELISA." Clin Chim Acta 328, no. 1-2 (February 2003): 59-69. Link to Item
  - Huebner, JL, Hanes, MA, Beekman, B, TeKoppele, JM, and Kraus, VB. "A comparative analysis of bone and cartilage metabolism in two strains of guinea-pig with varying degrees of naturally occurring osteoarthritis." Osteoarthritis Cartilage 10, no. 10 (October 2002): 758-767. Link to Item
  - Dragomir, AD, Kraus, VB, Renner, JB, Luta, G, Clark, A, Vilim, V, Hochberg, MC, Helmick, CG, and Jordan, JM. "Serum cartilage oligomeric matrix protein and clinical signs and symptoms of potential pre-radiographic hip and knee pathology." Osteoarthritis Cartilage 10, no. 9 (September 2002): 687-691. Link to Item
  - Flahiff, CM, Narmoneva, DA, Huebner, JL, Kraus, VB, Guilak, F, and Setton, LA. "Osmotic loading to determine the intrinsic material properties of guinea pig knee cartilage." J Biomech 35, no. 9 (September 2002): 1285-1290. Link to Item
  - Vilím, V, Olejárová, M, Machácek, S, Gatterová, J, Kraus, VB, and Pavelka, K. "Serum levels of cartilage oligomeric matrix protein (COMP) correlate with radiographic progression of knee osteoarthritis." Osteoarthritis Cartilage 10, no. 9 (September 2002): 707-713. Link to Item
  - Clark, AG, Rohrbaugh, AL, Otterness, I, and Kraus, VB. "The effects of ascorbic acid on cartilage metabolism in guinea pig articular cartilage explants." Matrix biology : journal of the International Society for Matrix Biology 21, no. 2 (March 2002): 175-184. Full Text
  - Fink, C, Cooper, HJ, Huebner, JL, Guilak, F, and Kraus, VB. "Precision and accuracy of a transportable dual-energy X-ray absorptiometry unit for bone mineral measurements in guinea pigs." Calcif Tissue Int 70, no. 3 (March 2002): 164-169. Full Text Link to Item
  - Kraus, VB, Huebner, JL, Fink, C, King, JB, Brown, S, Vail, TP, and Guilak, F. "Urea as a passive transport marker for arthritis biomarker studies." Arthritis Rheum 46, no. 2 (February 2002): 420-427. Link to Item
  - Carlson, CS, Guilak, F, Vail, TP, Gardin, JF, and Kraus, VB. "Synovial fluid biomarker levels predict articular cartilage damage following complete medial meniscectomy in the canine knee." J Orthop Res 20, no. 1 (January 2002): 92-100. Full Text Link to Item
  - Vilím, V, Vytásek, R, Olejárová, M, Machácek, S, Gatterová, J, Procházka, B, Kraus, VB, and Pavelka, K. "Serum cartilage oligomeric matrix protein reflects the presence of clinically diagnosed synovitis in patients with knee osteoarthritis." Osteoarthritis Cartilage 9, no. 7 (October 2001): 612-618. Full Text Link to Item
  - Wang, JY, Baer, AE, Kraus, VB, and Setton, LA. "Intervertebral disc cells exhibit differences in gene expression in alginate and monolayer culture." Spine (Phila Pa 1976) 26, no. 16 (August 15, 2001): 1747-1751. Link to Item
  - Hale, LP, Clark, AG, Li, J, Greer, PK, and Byers Kraus, V. "Age-related thymic atrophy in the guinea pig." Dev Comp Immunol 25, no. 5-6 (June 2001): 509-518. Link to Item
  - St Clair, EW, Wilkinson, WE, Pisetsky, DS, Sexton, DJ, Drew, R, Kraus, VB, and Greenwald, RA. "The effects of intravenous doxycycline therapy for rheumatoid arthritis: a randomized, double-blind, placebo-controlled trial." Arthritis Rheum 44, no. 5 (May 2001): 1043-1047. Full Text Link to Item
  - Baer, AE, Wang, JY, Kraus, VB, and Setton, LA. "Collagen gene expression and mechanical properties of intervertebral disc cell-alginate cultures." J Orthop Res 19, no. 1 (January 2001): 2-10. Full Text Link to Item
  - Kraus, VB, Clark, AG, Jordan, JM, Dragomir, AD, Luta, G, and Vilim, V. "Diagnosis of osteoarthritis in relation to molecular processes in cartilage: comment on the article by Clark et al - Reply." ARTHRITIS AND RHEUMATISM 43, no. 6 (June 2000): 1426-1427. Full Text Link to Item
  - Lindhorst, E, Vail, TP, Guilak, F, Wang, H, Setton, LA, Vilim, V, and Kraus, VB. "Longitudinal characterization of synovial fluid biomarkers in the canine meniscectomy model of osteoarthritis." J Orthop Res 18, no. 2 (March 2000): 269-280. Full Text Link to Item
  - Månsson, B, Heinegård, D, Saxne, T, Kraus, VB, Clark, AG, Jordan, JM, Dragomir, AD, Luta, G, and Vilim, V. "Diagnosis of osteoarthritis in relation to molecular processes in cartilage: Comment on the article by Clark et al [3] (multiple letters)." Arthritis and Rheumatism 43, no. 6 (2000): 1425-1427. Full Text
  - Clark, AG, Jordan, JM, Vilim, V, Renner, JB, Dragomir, AD, Luta, G, and Kraus, VB. "Serum cartilage oligomeric matrix protein reflects osteoarthritis presence and severity: the Johnston County Osteoarthritis Project." Arthritis Rheum 42, no. 11 (November 1999): 2356-2364. Full Text Link to Item
  - Huebner, JL, and Kraus, VB. "Expression of matrix metalloproteinase 1 in rodents: Reply." ARTHRITIS AND RHEUMATISM 42, no. 3 (March 1999): 590-590. Full Text Link to Item
  - Selman, M, Pardo, A, Huebner, JL, and Kraus, VB. "Expression of matrix metalloproteinase 1 in rodents: Comment on the article by Huebner et al [5] (multiple letters)." Arthritis and Rheumatism 42, no. 3 (1999): 590--.
  - Setton, LA, Baer, AE, Wang, JY, and Kraus, VB. "Biosynthesis of intervertebral disc matrix in vitro." Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings 2 (1999): 1325--.
  - Huebner, JL, Otterness, IG, Freund, EM, Caterson, B, and Kraus, VB. "Collagenase 1 and collagenase 3 expression in a guinea pig model of osteoarthritis." Arthritis Rheum 41, no. 5 (May 1998): 877-890. Full Text Link to Item
  - Bello, AE, Garrett, WE, Wang, H, Lohnes, J, DeLong, E, Caterson, B, and Kraus, VB. "Comparison of synovial fluid cartilage marker concentrations and chondral damage assessed arthroscopically in acute knee injury." Osteoarthritis Cartilage 5, no. 6 (November 1997): 419-426. Link to Item
  - Kraus, VB. "Pathogenesis and treatment of osteoarthritis." Med Clin North Am 81, no. 1 (January 1997): 85-112. (Review) Link to Item
  - Kraus, VB, Freund, EMN, Huebner, JL, and Caterson, B. "Collagenase in a guinea PK3 model of natural osteoarthrftis." Journal of Investigative Medicine 44, no. 3 (1996): 296a-.
  - Kraus, VB, Inostroza, JA, Yeung, K, Reinberg, D, and Nevins, JR. "Interaction of the Dr1 inhibitory factor with the TATA binding protein is disrupted by adenovirus E1A." Proc Natl Acad Sci U S A 91, no. 14 (July 5, 1994): 6279-6282. Link to Item
  - Taylor, DA, Kraus, VB, Schwarz, JJ, Olson, EN, and Kraus, WE. "E1A-mediated inhibition of myogenesis correlates with a direct physical interaction of E1A12S and basic helix-loop-helix proteins." Mol Cell Biol 13, no. 8 (August 1993): 4714-4727. Link to Item
  - TAYLOR, DA, KRAUS, VB, SCHWARZ, JJ, OLSON, EN, and KRAUS, WE. "E1A-MEDIATED INHIBITION OF MYOGENESIS - A DIRECT PHYSICAL INTERACTION OF E1A(12S) AND BHLH PROTEINS." JOURNAL OF CELLULAR BIOCHEMISTRY (March 13, 1993): 225-225. Link to Item
  - KRAUS, VB, INOSTROZA, JA, REINBERG, D, MORAN, E, and NEVINS, JR. "THE ACTIVATION OF THE HSP70-PROMOTER BY E1A COINCIDES WITH A RELEASE OF TBP FROM AN INTERACTION WITH THE INHIBITORY FACTOR DR1." JOURNAL OF CELLULAR BIOCHEMISTRY (January 9, 1993): 226-226. Link to Item
  - KRAUS, VB, INOSTROZA, JA, REINBERG, D, MORAN, E, and NEVINS, JR. "THE ACTIVATION OF THE HSP70 PROMOTER BY E1A COINCIDES WITH A RELEASE OF TBP FROM AN INTERACTION WITH THE INHIBITORY FACTOR-DR1." JOURNAL OF CELLULAR BIOCHEMISTRY (January 9, 1993): 60-60. Link to Item
  - Kraus, VB, Moran, E, and Nevins, JR. "Promoter-specific trans-activation by the adenovirus E1A12S product involves separate E1A domains." Mol Cell Biol 12, no. 10 (October 1992): 4391-4399. Link to Item
  - TAYLOR, DA, KRAUS, VB, and KRAUS, WE. "E1A-MEDIATED INHIBITION OF MYOGENESIS - A DIRECT PHYSICAL INTERACTION OF E1A(12S) AND BHLH PROTEINS." CIRCULATION 86, no. 4 (October 1992): 347-347. Link to Item
  - Chellappan, S, Kraus, VB, Kroger, B, Munger, K, Howley, PM, Phelps, WC, and Nevins, JR. "Adenovirus E1A, simian virus 40 tumor antigen, and human papillomavirus E7 protein share the capacity to disrupt the interaction between transcription factor E2F and the retinoblastoma gene product." Proc Natl Acad Sci U S A 89, no. 10 (May 15, 1992): 4549-4553. Link to Item
  - Raychaudhuri, P, Bagchi, S, Devoto, SH, Kraus, VB, Moran, E, and Nevins, JR. "Domains of the adenovirus E1A protein required for oncogenic activity are also required for dissociation of E2F transcription factor complexes." Genes Dev 5, no. 7 (July 1991): 1200-1211. Link to Item
  - Phelps, WC, Bagchi, S, Barnes, JA, Raychaudhuri, P, Kraus, V, Münger, K, Howley, PM, and Nevins, JR. "Analysis of trans activation by human papillomavirus type 16 E7 and adenovirus 12S E1A suggests a common mechanism." Journal of Virology 65, no. 12 (1991): 6922-6930.
  - Manzi, S, Kraus, VB, and St Clair, EW. "An unusual photoactivated skin eruption. Quinidine-induced livedo reticularis." Arch Dermatol 125, no. 3 (March 1989): 417-422. Link to Item
  - Manzi, S, Kraus, VB, and Clair, EW. "An Unusual Photoactivated Skin Eruption." Archives of Dermatology 125, no. 3 (1989): 419-420. Full Text
  - Kraus, VB, Harden, EA, Wittels, B, Moore, JO, and Haynes, BF. "Demonstration of phenotypic abnormalities of thymic epithelium in thymoma including two cases with abundant Langerhans cells." Am J Pathol 132, no. 3 (September 1988): 552-562. Link to Item
  - Kraus, VB, Baraniuk, JN, Hill, GB, and Allen, NB. "Ureaplasma urealyticum septic arthritis in hypogammaglobulinemia." J Rheumatol 15, no. 2 (February 1988): 369-371. Link to Item
  - Kraus, VB, Fulkerson, WJ, Gowen, MA, and Samuelson, WM. "Straw lung." N Engl J Med 312, no. 14 (April 4, 1985): 924-. (Letter) Link to Item
  - Kraus, VMB, Dasheiff, RM, Fanelli, RJ, and McNamara, JO. "Benzodiazepine receptor declines in hippocampal formation following limbic seizures." Brain Research 277, no. 2 (1983): 305-309.
  - Yin, Z, Fei, Z, Qiu, C, Brasher, MS, Kraus, VB, Zhao, W, Shi, X, and Zeng, Y. "Dietary diversity and cognitive function among elderly people: A population-based study (Published online)." The journal of nutrition, health & aging . Full Text
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