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Recent Publications


Bidirectional regulation of postmitotic H3K27me3 distributions underlie cerebellar granule neuron maturation dynamics.

Journal Article Elife · April 24, 2023 The functional maturation of neurons is a prolonged process that extends past the mitotic exit and is mediated by the chromatin-dependent orchestration of gene transcription programs. We find that expression of this maturation gene program in mouse cerebel ... Full text Link to item Cite

A reactive metabolite as an immune suppressant.

Journal Article Nature immunology · May 2020 Full text Cite

Evolved resistance to partial GAPDH inhibition results in loss of the Warburg effect and in a different state of glycolysis.

Journal Article J Biol Chem · January 3, 2020 Aerobic glycolysis or the Warburg effect (WE) is characterized by increased glucose uptake and incomplete oxidation to lactate. Although the WE is ubiquitous, its biological role remains controversial, and whether glucose metabolism is functionally differe ... Full text Link to item Cite
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