Selected Grants
Targeting Hepatocyte Senescence to Improve NAFLD
ResearchCo-Mentor · Awarded by National Institutes of Health · 2024 - 2029The Duke Preparing Research scholars In bioMEdical sciences (PRIME): Cancer Research Program
ResearchPreceptor · Awarded by National Cancer Institute · 2023 - 2028Training Program in Developmental and Stem Cell Biology
Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2001 - 2027Cell and Molecular Biology Training Program
Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2021 - 2026Roles of mitochondrial dynamics and mtDNA in senescence
ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2022 - 2026Pharmacological Sciences Training Grant
Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 2020 - 2025Basic Immunology Training Program
Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2020 - 2025Synthetic lethality by targeting the core senescent mechanism in lung cancer.
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2020 - 2025NGF recruits nerve fibers to reprogram an immunosuppressive microenvironment in melanoma
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2020 - 2025Targeting UHRF1 in combinational immunotherapy
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2019 - 2024Translational Research in Surgical Oncology
Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2002 - 2022Examining Biosynthesis and NAD+ Demand in the Warburg Effect
FellowshipSponsor · Awarded by National Institutes of Health · 2019 - 2022Understanding methionine metabolism and its therapeutic potential in cancer
ResearchAdvisor · Awarded by National Institutes of Health · 2019 - 2021Role of hedgehog signaling in tumor-associated macrophage polarization
FellowshipPrincipal Investigator · Awarded by National Institutes of Health · 2017 - 2021Pharmacological Sciences Training Program
Inst. Training Prgm or CMEParticipating Faculty Member · Awarded by National Institutes of Health · 1975 - 2020Organization and Function of Cellular Structure
Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 1975 - 2020Analysis of mechanisms associated with Her2-positive breast cancer resistance to therapy
ResearchPrincipal Investigator · Awarded by Department of Defense · 2016 - 2019Fibulin-3 as a Novel Biomarker and Trget in the Breast Tumor Microenvironment
ResearchKey Faculty · Awarded by Susan G. Komen Breast Cancer Foundation · 2015 - 2018The anti-senescence activity of trefoil factor 1
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2012 - 2018The Roles of MicroRNAs in Glioblastoma
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2012 - 2017Kinase Target of Diverse Cell Surface Receptors in Cancer Invasion and Metastasis
ResearchCollaborator · Awarded by National Institutes of Health · 2011 - 2017Research Training In Neuro-Oncology
Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 1998 - 2016Molecular determinants underlying herceptin sensitivity and resistance
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2014 - 2016Cancer Biology Training Grant
Inst. Training Prgm or CMEPrincipal Investigator · Awarded by National Cancer Institute · 1993 - 2016Determine the potential therapeutic effect of HDAC6 inhibitors in inhibiting breast cancer metastasis and glioblastoma growth in mouse models
ResearchPrincipal Investigator · Awarded by Acetylon Pharmaceuticals, Inc. · 2014 - 2015The role of TGF-beta in tumorigenesis
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2010 - 201527-hydroxycholesterol as a link between obesity and breast cancer pathogenesis
ResearchCo-Mentor · Awarded by National Institutes of Health · 2013 - 2014Preclinical Evaluation of PK2 Antagonists for Pancreatic Cancer
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2011 - 2013The Role of OTX2 in Molecular Pathogenesis of Medulloblastoma
ResearchConsultant · Awarded by National Institutes of Health · 2006 - 2012Mechanisms of TGF-B/Smad Signaling
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2008 - 2012TGFBI and tumorigenesis
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2006 - 2011Rad17- & p53-mediated apoptotic pathways in response to DNA damage
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2006 - 2011Research Training In Neuro-Oncology
Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2005 - 2010TGFbeta-PTEN Interactions in Glioma Biology & Therapy
ResearchConsultant · Awarded by National Institutes of Health · 2006 - 2008Molecular Mechanisms of SPARC Mediated Glioma Invasion
ResearchConsultant · Awarded by National Institutes of Health · 2006 - 2008TGF-Beta Signaling in MSCs and Osteoblast
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2004 - 2008Analysis of Rad17-mediated Checkpoint Signaling
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2002 - 2008Analysis of the Functional Role of TPF in Tumorigenesis
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2000 - 2005The Role Of Tumor Supressor Smads In Tgf-B Signaling
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 1998 - 2004Same Same
ResearchPrincipal Investigator · Awarded by US Army Medical Research · 1999 - 2002The Role Of Tgfb In Brain Tumors
ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 1998 - 2001Tgf-Beta Signaling Pathway And Cell Growth Regulation
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 1995 - 2001Tgf-B Signaling Pathway And Cell Growth Regulation
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 1996 - 1999Examination Of Tgfb Induced Cell Death Pathway
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 1995 - 1998Analysis Of Tgf-B Receptor Ii Signalling Mechanism
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 1994 - 1995Analysis Of Tgf Beta Receptor Ii Signalling Mechanism
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 1993 - 1995External Relationships
- Cancer Science Institute of Singapore
- Cell Research, Nature Publishing Group
- Feng Foundation
- Institute of Life Sciences, Zhejiang University
- Institute of Nutrition and Health, Chiese Academy of Sciences, Shanghai
- Joint Center for Life Sciences at Peking University and Tshinghua University
- Keymed Biosciences Inc.
- National Science Review, Editorial Board
- New Cornerstone Foundation
- Research Grants Council of Hong Kong
- Review Panel, Cancer Prevention & Research Institute of Texas
- Science China, Life Sciences
- TCRCure Biopharma
- Upstream Biotechnology
- Westlake University
- Wuhan University Taikang Medical Research Institute
This faculty member (or a member of their immediate family) has reported outside activities with the companies, institutions, or organizations listed above. This information is available to institutional leadership and, when appropriate, management plans are in place to address potential conflicts of interest.