Wei Chen
Assistant Professor of Pathology
Current Appointments & Affiliations
- Assistant Professor of Pathology, Pathology, Clinical Science Departments 2021
Contact Information
- Background
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Education, Training, & Certifications
- Fellowship, Gastrointestinal Pathology, University of Pittsburgh 2020 - 2021
- Fellowship, Surgical Pathology, Brigham and Women's Hospital 2019 - 2020
- Residency, Pathology (Ap/Cp), Case Western Reserve University 2015 - 2018
- Fellowship, Medical Oncology, Zhejiang University (China) 2012 - 2015
- Residency, Internal Medicine, Zhejiang University (China) 2009 - 2012
- M.D., Zhejiang University (China) 2009
- Publications & Artistic Works
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Selected Publications
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Academic Articles
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Chen, Wei, Lei Zhao, Agoston Agoston, Abby White, Emanuele Mazzola, Patrick J. Boyle, Vikram Deshpande, et al. “Florid Foreign Body-type Giant Cell Response to Keratin Is Associated With Improved Overall Survival in Patients Receiving Preoperative Therapy for Esophageal Squamous Cell Carcinoma.” American Journal of Surgical Pathology 45, no. 12 (December 2021): 1648–60. https://doi.org/10.1097/pas.0000000000001797.Full Text
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Chen, Wei, Lama Farchoukh, Lindsey Seigh, Douglas J. Hartman, and Reetesh K. Pai. “Combined histopathological risk score using TP53 protein expression, CD8 + T cell density and intratumoral budding is an independent predictor of neoadjuvant therapy response in rectal adenocarcinoma.” Histopathology 79, no. 5 (November 2021): 826–35. https://doi.org/10.1111/his.14430.Full Text
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Chen, Wei, Jason L. Hornick, and Christopher D. M. Fletcher. “NKX3.1 immunoreactivity is not identified in mesenchymal chondrosarcoma: a 25‐case cohort study.” Histopathology 78, no. 2 (January 2021): 334–37. https://doi.org/10.1111/his.14231.Full Text
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Chen, Wei, Zhenghong Lee, Amad Awadallah, Lan Zhou, and Wei Xin. “Peritumoral/vascular expression of PSMA as a diagnostic marker in hepatic lesions.” Diagnostic Pathology 15, no. 1 (December 2020). https://doi.org/10.1186/s13000-020-00982-4.Full Text
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Chen, Wei, Liwei Jia, Sanjay Gupta, and Gregory T. MacLennan. “The Role of Chronic Inflammation in Prostate Carcinogenesis: A Follow-Up Study.” Annals of Urologic Oncology, June 30, 2019, 1–8. https://doi.org/10.32948/auo.2019.01.14.Full Text
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Chen, Wei, Jennifer P. Ha, Hong Hong, and Robert W. Maitta. “Absolute immature platelet counts in the setting of suspected heparin-induced thrombocytopenia may predict anti-PF4-heparin immunoassay testing results.” Transfusion and Apheresis Science 57, no. 4 (August 2018): 507–11. https://doi.org/10.1016/j.transci.2018.04.001.Full Text
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Chen, Wei, Carmen J. Julius, and Robin M. Elliott. “Renal angiofibroma: A case report.” Human Pathology: Case Reports 12 (June 2018): 29–31. https://doi.org/10.1016/j.ehpc.2018.01.001.Full Text
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SUI, X. I. N. B. I. N. G., Y. O. N. G. FANG, H. A. I. Z. H. O. U. LOU, K. A. I. F. E. N. G. WANG, Y. U. ZHENG, F. A. N. G. LOU, W. E. I. JIN, et al. “p53 suppresses stress-induced cellular senescence via regulation of autophagy under the deprivation of serum.” Molecular Medicine Reports 11, no. 2 (February 2015): 1214–20. https://doi.org/10.3892/mmr.2014.2853.Full Text
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Fang, Yong, Wei Chen, Xiao Liang, Da Li, HaiZhou Lou, Renbiao Chen, Kaifeng Wang, and HongMing Pan. “Comparison of long-term effectiveness and complications of radiofrequency ablation with hepatectomy for small hepatocellular carcinoma.” Journal of Gastroenterology and Hepatology 29, no. 1 (January 2014): 193–200. https://doi.org/10.1111/jgh.12441.Full Text
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Zhou, W., H. Zhu, W. Chen, X. Hu, X. Pang, J. Zhang, X. Huang, B. Fang, and C. He. “Treatment of patient tumor-derived colon cancer xenografts by a TRAIL gene-armed oncolytic adenovirus.” Cancer Gene Therapy 18, no. 5 (May 2011): 336–45. https://doi.org/10.1038/cgt.2010.83.Full Text
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Chen, Wei, Jun Wang, Endi Wang, Ying Lu, Sean K. Lau, Lawrence M. Weiss, and Qin Huang. “Detection of clonal lymphoid receptor gene rearrangements in langerhans cell histiocytosis.” Am J Surg Pathol 34, no. 7 (July 2010): 1049–57. https://doi.org/10.1097/PAS.0b013e3181e5341a.Full Text Link to Item
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Lu, Ying, Xiaohui Zhao, Endi Wang, Wei Chen, and Qin Huang. “ALK-negative anaplastic large cell lymphoma with extensive peripheral blood and bone marrow involvements manifested as "leukemic phase".” Leuk Res 34, no. 4 (April 2010): 475–82. https://doi.org/10.1016/j.leukres.2009.07.034.Full Text Link to Item
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Chen, Wei, Endi Wang, Ying Lu, Karl K. Gaal, and Qin Huang. “Therapy-related acute lymphoblastic leukemia without 11q23 abnormality: report of six cases and a literature review.” Am J Clin Pathol 133, no. 1 (January 2010): 75–82. https://doi.org/10.1309/AJCPYWC6AQC7BAVJ.Full Text Link to Item
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Lu, Ying, Wengang Chen, Wei Chen, Anthony Stein, Lawrence M. Weiss, and Qin Huang. “C/EBPA gene mutation and C/EBPA promoter hypermethylation in acute myeloid leukemia with normal cytogenetics.” American Journal of Hematology, 2010, NA-NA. https://doi.org/10.1002/ajh.21706.Full Text
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Lu, Ying, Wengang Chen, Wei Chen, Anthony Stein, Lawrence M. Weiss, and Qin Huang. “C/Ebpa Gene Mutation and C/Ebpa Promoter Hypermethylation in Acute Myeloid Leukemia with Normal Cytogenetics.” Blood 114, no. 22 (November 20, 2009): 1570–1570. https://doi.org/10.1182/blood.v114.22.1570.1570.Full Text
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Chen, Wei, and Qin Huang. “Detection of FLT3/ITD, JAK2(V617F) and NPM1 gene mutations in chronic myelomonocytic leukemia.” Leukemia Research 33, no. 11 (November 2009): e207–9. https://doi.org/10.1016/j.leukres.2009.05.015.Full Text
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Hu, Xiaotong, Wei Chen, Fubiao Zhang, Qinglan Shi, Jianbing Hu, and Chao He. “Depletion of the proteasome subunit PSMA7 inhibits colorectal cancer cell tumorigenicity and migration.” Oncology Reports 22, no. 05 (September 16, 2009). https://doi.org/10.3892/or_00000561.Full Text
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Chen, Wei, Mark McNamara, Young Kim, and Qin Huang. “t(11;14) Plasma Cell Disorder Presents as a True Nonsecretory, Nonproducer Multiple Myeloma.” Clinical Lymphoma and Myeloma 9, no. 3 (June 2009): 243–46. https://doi.org/10.3816/clm.2009.n.048.Full Text
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Chen, Wei, Sean K. Lau, Dean Fong, Jun Wang, Endi Wang, Daniel A. Arber, Lawrence M. Weiss, and Qin Huang. “High frequency of clonal immunoglobulin receptor gene rearrangements in sporadic histiocytic/dendritic cell sarcomas.” Am J Surg Pathol 33, no. 6 (June 2009): 863–73. https://doi.org/10.1097/PAS.0b013e31819287b8.Full Text Link to Item
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Chen, Wei, Qin Huang, Craig W. Zuppan, Edward H. Rowsell, Jeffrey D. Cao, Lawrence M. Weiss, and Jun Wang. “Complete Absence of KSHV/HHV-8 in Posttransplant Lymphoproliferative Disorders.” American Journal of Clinical Pathology 131, no. 5 (May 2009): 632–39. https://doi.org/10.1309/ajcp2t4iiizkbhmi.Full Text
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Chen, wei, Xiaotong Hu, Qinglan Shi, Fubiao Zhang, and Chao He. “Knockdown of the novel proteasome subunit Adrm1 located on the 20q13 amplicon inhibits colorectal cancer cell migration, survival and tumorigenicity.” Oncology Reports 21, no. 2 (February 1, 2009): 531–37. https://doi.org/10.3892/or_00000254.Full Text
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Hu, Xiao-Tong, Wei Chen, Da Wang, Qing-Lan Shi, Fu-Biao Zhang, Yong-Qiang Liao, Mei Jin, and Chao He. “The proteasome subunit PSMA7 located on the 20q13 amplicon is overexpressed and associated with liver metastasis in colorectal cancer.” Oncology Reports, n.d. https://doi.org/10.3892/or.19.2.441.Full Text
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Sui, Xinbing, Yinghua Xu, Jie Yang, Yong Fang, Haizhou Lou, Weidong Han, Maolin Zhang, et al. “Use of Metformin Alone Is Not Associated with Survival Outcomes of Colorectal Cancer Cell but AMPK Activator AICAR Sensitizes Anticancer Effect of 5-Fluorouracil through AMPK Activation.” Plos One 9, no. 5 (n.d.): e97781–e97781. https://doi.org/10.1371/journal.pone.0097781.Full Text
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Book Sections
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Chen, Wei, and Qin Huang. “Hairy Cell Leukemia, Hairy Cell Leukemia Variant, and Splenic Diffuse Red Pulp Small B-Cell Lymphoma.” In Diagnostic Pathology of Hematopoietic Disorders of Spleen and Liver, edited by Ling Zhang. Springer Nature, 2020.
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Conference Papers
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Huang, Q., W. Chen, J. Wang, E. Wang, Y. Lu, S. K. Lau, and L. M. Weiss. “Detection of Clonal Lymphoid Receptor Gene Rearrangements in Langerhans Cell Histiocytosis.” In Modern Pathology, 23:302A-302A. NATURE PUBLISHING GROUP, 2010.Link to Item
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Huang, Q., W. Chen, J. Wang, E. Wang, Y. Lu, S. K. Lau, and L. M. Weiss. “Detection of Clonal Lymphoid Receptor Gene Rearrangements in Langerhans Cell Histiocytosis.” In Laboratory Investigation, 90:302A-302A, 2010.Link to Item
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Chen, W., S. K. Lau, D. Fong, J. Wang, E. Wang, D. A. Arber, L. M. Weiss, and Q. Huang. “High Frequency of Clonal Immunoglobulin Receptor Gene Rearrangements in Sporadic Histiocytic/Dendritic Sarcomas.” In Modern Pathology, 22:258A-259A. NATURE PUBLISHING GROUP, 2009.Link to Item
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Chen, W., S. K. Lau, D. Fong, J. Wang, E. Wang, D. A. Arber, and Q. Huang. “High Frequency of Clonal Immunoglobulin Receptor Gene Rearrangements in Sporadic Histiocytic/Dendritic Sarcomas.” In Laboratory Investigation, 89:258A-259A. NATURE PUBLISHING GROUP, 2009.Link to Item
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