Current Appointments & Affiliations
Associate Professor Emeritus in Medicine
·
2021 - Present
Medicine, Infectious Diseases,
Medicine
Recent Publications
Efficacy of Liposomal Nystatin in a Rabbit Model of Cryptococcal Meningitis.
Journal Article J Fungi (Basel) · July 26, 2024 Cryptococcal meningitis (CM) causes significant global morbidity and mortality. Current therapeutic strategies rely on deoxycholated or liposomal forms of the polyene amphotericin B. Nystatin is also a polyene with broad-spectrum antimicrobial activity. Tr ... Full text Link to item CiteA ketogenic diet enhances fluconazole efficacy in murine models of systemic fungal infection.
Journal Article mBio · May 8, 2024 Invasive fungal infections are a significant public health concern, with mortality rates ranging from 20% to 85% despite current treatments. Therefore, we examined whether a ketogenic diet could serve as a successful treatment intervention in murine models ... Full text Link to item CitePharmacodynamics of ATI-2307 in a rabbit model of cryptococcal meningoencephalitis.
Journal Article Antimicrob Agents Chemother · October 18, 2023 Cryptococcal meningoencephalitis (CM) is a devastating fungal disease with high morbidity and mortality. The current regimen that is standard-of-care involves a combination of three different drugs administered for up to one year. There is a critical need ... Full text Link to item CiteRecent Grants
Optimization of detection and monitoring of environmental fungal contamination to establish baseline contamination rates (BAA-75D301-22-R-72097 ) OPTION YEAR TWO
ResearchConsultant · Awarded by Centers for Disease Control and Prevention · 2022 - 2024The Role of Host Inositol in Cryptococcus Biology and Pathogenesis
ResearchResearch Scientist · Awarded by Rutgers, The State University of New Jersey · 2016 - 2021Study Isavuconazole in a Rabbit Model of Cryptococcal Meningoencephalitis Caused by Cryptococccal gattii
ResearchResearch Scientist · Awarded by Astellas Pharma Inc. · 2017 - 2019View All Grants
Education, Training & Certifications
University of North Carolina, Chapel Hill ·
1979
M.S.
East Carolina University ·
1977
B.S.