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William R. Auger

William R. Auger

Adjunct Professor in the Department of Medicine
Medicine, Pulmonary, Allergy, and Critical Care Medicine
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Selected Publications

Computed Tomography Pulmonary Angiography Prediction of Adverse Long-Term Outcomes in Chronic Thromboembolic Pulmonary Hypertension: Correlation with Hemodynamic Measurements Pre- and Post-Pulmonary Endarterectomy.

Journal Article Tomography · September 26, 2023 CT pulmonary angiography is commonly used in diagnosing chronic thromboembolic pulmonary hypertension (CTEPH). This work was conducted to determine if cardiac chamber size on CTPA may also be useful for predicting the outcome of CTEPH treatment. A retrospe ... Full text Link to item Cite

Distal vessel pulmonary thromboendarterectomy: Results from a single institution.

Journal Article J Heart Lung Transplant · August 2023 BACKGROUND: Chronic thromboembolic pulmonary hypertension (CTEPH) is primarily managed by pulmonary thromboendarterectomy (PTE). As advanced surgical techniques permit resection at the segmental and subsegmental level, PTE can now be curative for CTEPH mos ... Full text Link to item Cite

Pulmonary Vein Sign on Computed Tomography Pulmonary Angiography in Proximal and Distal Chronic Thromboembolic Pulmonary Hypertension With Hemodynamic Correlation.

Journal Article J Thorac Imaging · May 1, 2023 BACKGROUND: Pulmonary vein sign (PVS) indicates abnormal pulmonary venous flow on computed tomography pulmonary angiography (CTPA) is a frequent finding in proximal chronic thromboembolic pulmonary hypertension (CTEPH). PVS's occurrence in distal CTEPH and ... Full text Link to item Cite

Refined Balloon Pulmonary Angioplasty in Chronic Thromboembolic Pulmonary Hypertension: Initial Results of U.S. Regional Program

Journal Article JACC: Advances · May 1, 2023 Background: Balloon pulmonary angioplasty (BPA) is rapidly evolving therapeutic option for patients with nonsurgical chronic thromboembolic pulmonary hypertension (CTEPH). There are few U.S. studies that have reported on the outcomes of this novel therapeu ... Full text Cite

Biatrial Volumetric Assessment by Non-ECG-Gated CT Pulmonary Angiography Correlated with Transthoracic Echocardiography in Patients with Normal Diastology.

Journal Article Tomography · November 17, 2022 Atrial size is a predictor of cardiovascular mortality. Non-ECG-gated computed tomography pulmonary angiography (CTPA) is a common test for cardiopulmonary evaluation but normative values for biatrial volumes are lacking. We derived normal CT biatrial volu ... Full text Link to item Cite

Interventional Imaging Roadmap to Successful Balloon Pulmonary Angioplasty for Chronic Thromboembolic Pulmonary Hypertension

Journal Article Journal of the Society for Cardiovascular Angiography and Interventions · November 1, 2022 Balloon pulmonary angioplasty (BPA) is an evolving treatment modality for patients with chronic thromboembolic pulmonary hypertension (CTEPH) who are not candidates for pulmonary endarterectomy. Although several imaging modalities currently exist for evalu ... Full text Cite

Development of an international standard set of outcome measures for patients with venous thromboembolism: an International Consortium for Health Outcomes Measurement consensus recommendation.

Journal Article Lancet Haematol · September 2022 The International Consortium for Health Outcomes Measurement assembled an international working group of venous thromboembolism experts and patient representatives to develop a standardised minimum set of outcomes and outcome measurements for integration i ... Full text Link to item Cite

Inflammatory pseudotumor mimicking chronic pulmonary embolism or pulmonary artery sarcoma: Report of five cases

Journal Article Pulmonary Circulation · January 1, 2022 Inflammatory pseudotumor (IPT), also known as plasma cell granuloma, is a rare lesion of unknown etiology that occurs in many organs, especially in the lung. Here we report five cases of IPT arising in pulmonary artery mimicking chronic thromboembolic dise ... Full text Cite

Results From the United States Chronic Thromboembolic Pulmonary Hypertension Registry: Enrollment Characteristics and 1-Year Follow-up.

Conference Chest · November 2021 BACKGROUND: The United States Chronic Thromboembolic Pulmonary Hypertension Registry (US-CTEPH-R) was designed to characterize the demographic characteristics, evaluation, clinical course, and outcomes of surgical and nonsurgical therapies for patients wit ... Full text Link to item Cite

Evaluation and management of patients with chronic thromboembolic pulmonary hypertension - consensus statement from the ISHLT.

Journal Article J Heart Lung Transplant · November 2021 ISHLT members have recognized the importance of a consensus statement on the evaluation and management of patients with chronic thromboembolic pulmonary hypertension. The creation of this document required multiple steps, including the engagement of the IS ... Full text Link to item Cite

May-Thurner Anatomy in Patients With Chronic Thromboembolic Pulmonary Hypertension: An Important Clinical Association.

Journal Article JACC Cardiovasc Interv · September 13, 2021 OBJECTIVES: The aim of this study was to investigate the incidence of May-Thurner anatomy (MTA) in patients with chronic thromboembolic pulmonary hypertension (CTEPH) and identify its predictors. BACKGROUND: MTA is an anatomical variant characterized by co ... Full text Link to item Cite

The United States Chronic Thromboembolic Pulmonary Hypertension Registry: Protocol for a prospective, longitudinal study

Journal Article JMIR Research Protocols · May 1, 2021 Background: Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare sequela of acute pulmonary embolism that is treatable when recognized. Awareness of this disease has increased with recent advancements in therapeutic options, but delays in diagno ... Full text Cite

Evaluation of Routine Coronary Angiography Before Pulmonary Thromboendarterectomy.

Journal Article Ann Thorac Surg · May 2021 BACKGROUND: At the University of California, San Diego, routine coronary angiography has generally been performed in men 40 years of age and older and women 45 years of age and older before pulmonary thromboendarterectomy for chronic thromboembolic pulmona ... Full text Link to item Cite

Chronic thromboembolic pulmonary hypertension

Chapter · April 15, 2021 Chronic thromboembolic pulmonary hypertension (CTEPH) is a unique form of pulmonary vascular disease. This chapter will provide an overview of current insights into the prevalence and pathophysiology of this disease, review the diagnostic approach to patie ... Cite

Abnormal Pulmonary Venous Filling: An Adjunct Feature in the Computed Tomography Pulmonary Angiogram Assessment of Chronic Thromboembolic Pulmonary Hypertension.

Journal Article J Am Heart Assoc · November 3, 2020 Background Hypodense filling defects within the pulmonary veins on computed tomography described as pulmonary vein sign (PVS) have been noted in acute pulmonary embolism and shown to be associated with poor prognosis. We evaluated venous flow abnormalities ... Full text Link to item Cite

Cangrelor and Heparin for Pulmonary Thromboendarterectomy in Heparin-Induced Thrombocytopenia.

Journal Article Ann Thorac Surg · September 2020 Perioperative anticoagulation management for patients with heparin-induced thrombocytopenia requiring cardiopulmonary bypass and deep hypothermic circulatory arrest presents a clinical challenge. Alternative anticoagulants have been used but can cause sign ... Full text Link to item Cite

Surgical and Percutaneous Interventions for Chronic Thromboembolic Pulmonary Hypertension.

Journal Article Cardiol Clin · May 2020 The treatment of chronic thromboembolic pulmonary hypertension has expanded considerably. The ability to endarterectomize chronic thromboembolic material, the availability of pulmonary hypertension medical therapy to treat inoperable chronic thromboembolic ... Full text Link to item Cite

Computed Tomography Pulmonary Angiography Prediction of Adverse Long-Term Outcomes in Chronic Thromboembolic Pulmonary Hypertension: Correlation with Hemodynamic Measurements Pre- and Post-Pulmonary Endarterectomy.

Journal Article Tomography · September 26, 2023 CT pulmonary angiography is commonly used in diagnosing chronic thromboembolic pulmonary hypertension (CTEPH). This work was conducted to determine if cardiac chamber size on CTPA may also be useful for predicting the outcome of CTEPH treatment. A retrospe ... Full text Link to item Cite

Distal vessel pulmonary thromboendarterectomy: Results from a single institution.

Journal Article J Heart Lung Transplant · August 2023 BACKGROUND: Chronic thromboembolic pulmonary hypertension (CTEPH) is primarily managed by pulmonary thromboendarterectomy (PTE). As advanced surgical techniques permit resection at the segmental and subsegmental level, PTE can now be curative for CTEPH mos ... Full text Link to item Cite

Pulmonary Vein Sign on Computed Tomography Pulmonary Angiography in Proximal and Distal Chronic Thromboembolic Pulmonary Hypertension With Hemodynamic Correlation.

Journal Article J Thorac Imaging · May 1, 2023 BACKGROUND: Pulmonary vein sign (PVS) indicates abnormal pulmonary venous flow on computed tomography pulmonary angiography (CTPA) is a frequent finding in proximal chronic thromboembolic pulmonary hypertension (CTEPH). PVS's occurrence in distal CTEPH and ... Full text Link to item Cite

Refined Balloon Pulmonary Angioplasty in Chronic Thromboembolic Pulmonary Hypertension: Initial Results of U.S. Regional Program

Journal Article JACC: Advances · May 1, 2023 Background: Balloon pulmonary angioplasty (BPA) is rapidly evolving therapeutic option for patients with nonsurgical chronic thromboembolic pulmonary hypertension (CTEPH). There are few U.S. studies that have reported on the outcomes of this novel therapeu ... Full text Cite

Biatrial Volumetric Assessment by Non-ECG-Gated CT Pulmonary Angiography Correlated with Transthoracic Echocardiography in Patients with Normal Diastology.

Journal Article Tomography · November 17, 2022 Atrial size is a predictor of cardiovascular mortality. Non-ECG-gated computed tomography pulmonary angiography (CTPA) is a common test for cardiopulmonary evaluation but normative values for biatrial volumes are lacking. We derived normal CT biatrial volu ... Full text Link to item Cite

Interventional Imaging Roadmap to Successful Balloon Pulmonary Angioplasty for Chronic Thromboembolic Pulmonary Hypertension

Journal Article Journal of the Society for Cardiovascular Angiography and Interventions · November 1, 2022 Balloon pulmonary angioplasty (BPA) is an evolving treatment modality for patients with chronic thromboembolic pulmonary hypertension (CTEPH) who are not candidates for pulmonary endarterectomy. Although several imaging modalities currently exist for evalu ... Full text Cite

Development of an international standard set of outcome measures for patients with venous thromboembolism: an International Consortium for Health Outcomes Measurement consensus recommendation.

Journal Article Lancet Haematol · September 2022 The International Consortium for Health Outcomes Measurement assembled an international working group of venous thromboembolism experts and patient representatives to develop a standardised minimum set of outcomes and outcome measurements for integration i ... Full text Link to item Cite

Inflammatory pseudotumor mimicking chronic pulmonary embolism or pulmonary artery sarcoma: Report of five cases

Journal Article Pulmonary Circulation · January 1, 2022 Inflammatory pseudotumor (IPT), also known as plasma cell granuloma, is a rare lesion of unknown etiology that occurs in many organs, especially in the lung. Here we report five cases of IPT arising in pulmonary artery mimicking chronic thromboembolic dise ... Full text Cite

Results From the United States Chronic Thromboembolic Pulmonary Hypertension Registry: Enrollment Characteristics and 1-Year Follow-up.

Conference Chest · November 2021 BACKGROUND: The United States Chronic Thromboembolic Pulmonary Hypertension Registry (US-CTEPH-R) was designed to characterize the demographic characteristics, evaluation, clinical course, and outcomes of surgical and nonsurgical therapies for patients wit ... Full text Link to item Cite

Evaluation and management of patients with chronic thromboembolic pulmonary hypertension - consensus statement from the ISHLT.

Journal Article J Heart Lung Transplant · November 2021 ISHLT members have recognized the importance of a consensus statement on the evaluation and management of patients with chronic thromboembolic pulmonary hypertension. The creation of this document required multiple steps, including the engagement of the IS ... Full text Link to item Cite

May-Thurner Anatomy in Patients With Chronic Thromboembolic Pulmonary Hypertension: An Important Clinical Association.

Journal Article JACC Cardiovasc Interv · September 13, 2021 OBJECTIVES: The aim of this study was to investigate the incidence of May-Thurner anatomy (MTA) in patients with chronic thromboembolic pulmonary hypertension (CTEPH) and identify its predictors. BACKGROUND: MTA is an anatomical variant characterized by co ... Full text Link to item Cite

The United States Chronic Thromboembolic Pulmonary Hypertension Registry: Protocol for a prospective, longitudinal study

Journal Article JMIR Research Protocols · May 1, 2021 Background: Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare sequela of acute pulmonary embolism that is treatable when recognized. Awareness of this disease has increased with recent advancements in therapeutic options, but delays in diagno ... Full text Cite

Evaluation of Routine Coronary Angiography Before Pulmonary Thromboendarterectomy.

Journal Article Ann Thorac Surg · May 2021 BACKGROUND: At the University of California, San Diego, routine coronary angiography has generally been performed in men 40 years of age and older and women 45 years of age and older before pulmonary thromboendarterectomy for chronic thromboembolic pulmona ... Full text Link to item Cite

Chronic thromboembolic pulmonary hypertension

Chapter · April 15, 2021 Chronic thromboembolic pulmonary hypertension (CTEPH) is a unique form of pulmonary vascular disease. This chapter will provide an overview of current insights into the prevalence and pathophysiology of this disease, review the diagnostic approach to patie ... Cite

Abnormal Pulmonary Venous Filling: An Adjunct Feature in the Computed Tomography Pulmonary Angiogram Assessment of Chronic Thromboembolic Pulmonary Hypertension.

Journal Article J Am Heart Assoc · November 3, 2020 Background Hypodense filling defects within the pulmonary veins on computed tomography described as pulmonary vein sign (PVS) have been noted in acute pulmonary embolism and shown to be associated with poor prognosis. We evaluated venous flow abnormalities ... Full text Link to item Cite

Cangrelor and Heparin for Pulmonary Thromboendarterectomy in Heparin-Induced Thrombocytopenia.

Journal Article Ann Thorac Surg · September 2020 Perioperative anticoagulation management for patients with heparin-induced thrombocytopenia requiring cardiopulmonary bypass and deep hypothermic circulatory arrest presents a clinical challenge. Alternative anticoagulants have been used but can cause sign ... Full text Link to item Cite

Surgical and Percutaneous Interventions for Chronic Thromboembolic Pulmonary Hypertension.

Journal Article Cardiol Clin · May 2020 The treatment of chronic thromboembolic pulmonary hypertension has expanded considerably. The ability to endarterectomize chronic thromboembolic material, the availability of pulmonary hypertension medical therapy to treat inoperable chronic thromboembolic ... Full text Link to item Cite

Ramelteon for Prevention of Postoperative Delirium: A Randomized Controlled Trial in Patients Undergoing Elective Pulmonary Thromboendarterectomy.

Journal Article Crit Care Med · December 2019 OBJECTIVES: To assess the efficacy of ramelteon in preventing delirium, an acute neuropsychiatric condition associated with increased morbidity and mortality, in the perioperative, ICU setting. DESIGN: Parallel-arm, randomized, double-blinded, placebo-cont ... Full text Link to item Cite

Atrial arrhythmias after pulmonary thromboendarterectomy.

Journal Article J Card Surg · May 2019 BACKGROUND AND OBJECTIVES: Atrial arrhythmias (AAs) are common after cardiac surgeries including pulmonary thromboendarterectomy (PTE). This study was done to identify patients at highest risk of developing post-PTE AA and their length of stay (LOS). METHO ... Full text Link to item Cite

The ADAMTS13-VWF axis is dysregulated in chronic thromboembolic pulmonary hypertension.

Journal Article Eur Respir J · March 2019 Chronic thromboembolic pulmonary hypertension (CTEPH) is an important consequence of pulmonary embolism that is associated with abnormalities in haemostasis. We investigated the ADAMTS13-von Willebrand factor (VWF) axis in CTEPH, including its relationship ... Full text Link to item Cite

Case series of seven women with uterine fibroids associated with venous thromboembolism and chronic thromboembolic disease

Journal Article Pulmonary Circulation · January 1, 2019 Uterine fibroids have been described as an associate to acute venous thromboembolism (VTE), with case reports showing an association between large uterine fibroids, acute deep venous thrombosis (DVT), and acute pulmonary embolism (PE). However, there is li ... Full text Cite

Validation of a claims-based algorithm to identify patients with chronic thromboembolic pulmonary hypertension using electronic health record data

Journal Article Pulmonary Circulation · January 1, 2019 This study aimed to validate an algorithm developed to identify chronic thromboembolic pulmonary hypertension (CTEPH) among patients with a history of pulmonary embolism. Validation was halted because too few patients had gold-standard evidence of CTEPH in ... Full text Cite

Contribution of Cardiac Implantable Electronic Devices to Thrombus Formation in Patients With Chronic Thromboembolic Pulmonary Hypertension.

Journal Article JACC Clin Electrophysiol · November 2018 OBJECTIVES: This study aimed to identify the prevalence of cardiac implantable electronic devices (CIEDs) in patients with chronic thromboembolic pulmonary hypertension (CTEPH) and to describe the associated disease burden. BACKGROUND: CTEPH is a debilitat ... Full text Link to item Cite

Chronic Thromboembolic Pulmonary Hypertension: An Update.

Journal Article Clin Chest Med · September 2018 Chronic thromboembolic pulmonary hypertension (CTEPH) is a progressive pulmonary vascular disease with significant morbidity. It is a result of an alternate natural history in which there is limited resolution of thromboemboli with pulmonary artery obstruc ... Full text Link to item Cite

Chronic Thromboembolic Pulmonary Hypertension: Evolving Therapeutic Approaches for Operable and Inoperable Disease.

Journal Article J Am Coll Cardiol · May 29, 2018 Chronic thromboembolic pulmonary hypertension (CTEPH), a rare consequence of an acute pulmonary embolism, is a disease that is underdiagnosed, and surgical pulmonary thromboendarterectomy (PTE) remains the preferred therapy. However, determination of opera ... Full text Link to item Cite

Reply to Suissa and Ariel: The FULFIL Trial.

Journal Article Am J Respir Crit Care Med · February 15, 2018 Full text Link to item Cite

Pulmonary hypertension

Chapter · January 1, 2018 Full text Cite

Right Ventricular Dyssynchrony Before and After Pulmonary Thromboendarterectomy in Patients with Chronic Thromboembolic Pulmonary Hypertension

Journal Article Structural Heart · July 4, 2017 Background: Left ventricular dyssynchrony has been studied extensively, but this is not the case with right ventricular (RV) dyssynchrony. Our aim was to investigate RV dyssynchrony through 2D speckle strain imaging in patients with chronic thromboembolic ... Full text Cite

Tricuspid annular plane systolic excursion in chronic thromboembolic pulmonary hypertension before and after pulmonary thromboendarterectomy.

Journal Article Echocardiography · December 2016 BACKGROUND: Right ventricular function is impaired in chronic thromboembolic pulmonary hypertension (CTEPH). Tricuspid annular plane systolic excursion (TAPSE) and right ventricular fractional area change (RVFAC) have been shown to help assess right ventri ... Full text Link to item Cite

Diagnostic Evaluation of Chronic Thromboembolic Pulmonary Hypertension.

Conference Ann Am Thorac Soc · July 2016 Pulmonary hypertension is defined by a mean pulmonary artery pressure greater than 25 mm Hg. Chronic thromboembolic pulmonary hypertension (CTEPH) is defined as pulmonary hypertension in the presence of an organized thrombus within the pulmonary vascular b ... Full text Link to item Cite

Chronic Thromboembolic Pulmonary Hypertension. The Journey from a Curiosity to a Cure.

Journal Article Ann Am Thorac Soc · July 2016 Chronic thromboembolic pulmonary hypertension is a progressive and life-threatening condition that is believed to be related to inadequate dissolution of acute pulmonary thromboemboli, followed by fibrotic organization. Without appropriate treatment, progr ... Full text Link to item Cite

Chronic thromboembolic pulmonary hypertension: detection, medical and surgical treatment approach, and current outcomes.

Journal Article Heart Fail Rev · May 2016 Pulmonary hypertension due to chronic thromboembolic disease is potentially curable with pulmonary thromboendarterectomy surgery. As a result, it is important for clinicians to recognize and appropriately diagnose this form of pulmonary hypertension. Advan ... Full text Link to item Cite

Usefulness of Low Cardiac Index to Predict Sleep-Disordered Breathing in Chronic Thromboembolic Pulmonary Hypertension.

Journal Article Am J Cardiol · March 15, 2016 Patients with chronic thromboembolic pulmonary hypertension (CTEPH) often have substantial right ventricular dysfunction. The resulting low cardiac index might predispose to sleep disordered breathing (SDB) by increasing ventilatory instability. The preval ... Full text Link to item Cite

Treatment of Chronic Thromboembolic Pulmonary Hypertension: The Role of Medical Therapy and Balloon Pulmonary Angioplasty.

Journal Article Methodist Debakey Cardiovasc J · 2016 Chronic thromboembolic pulmonary hypertension (CTEPH) is a potentially curable disease when treated with pulmonary thromboendarterectomy (PTE). However, even at experienced surgical centers, nearly one-third of patients with CTEPH will be deemed inoperable ... Full text Link to item Cite

Efficacy of a Low-Tidal Volume Ventilation Strategy to Prevent Reperfusion Lung Injury after Pulmonary Thromboendarterectomy.

Journal Article Ann Am Thorac Soc · October 2015 RATIONALE: Reperfusion lung injury is a postoperative complication of pulmonary thromboendarterectomy that can significantly affect morbidity and mortality. Studies in other postoperative patient populations have demonstrated a reduction in acute lung inju ... Full text Link to item Cite

Right ventricular strain before and after pulmonary thromboendarterectomy in patients with chronic thromboembolic pulmonary hypertension.

Journal Article Echocardiography · July 2015 BACKGROUND: Right ventricular (RV) function is significantly impaired in patients with chronic thromboembolic pulmonary hypertension (CTEPH). Two-dimensional speckle tracking RV strain and strain rate are novel methods to assess regional RV systolic functi ... Full text Link to item Cite

Prevalence of coronary artery-pulmonary artery collaterals in patients with chronic thromboembolic pulmonary hypertension

Journal Article Pulmonary Circulation · June 1, 2015 This study sought to determine the prevalence of coronary artery-pulmonary artery collaterals in patients with chronic thromboembolic pulmonary hypertension (CTEPH) and to correlate their presence with the degree of clot burden. CTEPH is a treatable cause ... Full text Cite

Chronic Thromboembolic Pulmonary Hypertension: Surgical Treatment

Chapter · January 1, 2015 Over the past quarter century, the recognition, evaluation, and management of patients with chronic thromboembolic pulmonary hypertension (CTEPH) have experienced considerable forward strides. This has been accompanied by a better understanding of the risk ... Full text Cite

Baseline body mass index does not significantly affect outcomes after pulmonary thromboendarterectomy.

Journal Article Ann Thorac Surg · November 2014 BACKGROUND: Obesity is a common comorbidity of patients with chronic thromboembolic pulmonary hypertension referred for pulmonary thromboendarterectomy, yet the effect of obesity on pulmonary thromboendarterectomy outcomes has not been well described. METH ... Full text Link to item Cite

Assessment of left atrial volume before and after pulmonary thromboendarterectomy in chronic thromboembolic pulmonary hypertension.

Journal Article Cardiovasc Ultrasound · August 11, 2014 BACKGROUND: Impaired left ventricular diastolic filling is common in chronic thromboembolic pulmonary hypertension (CTEPH), and recent studies support left ventricular underfilling as a cause. To investigate this further, we assessed left atrial volume ind ... Full text Link to item Cite

Echocardiographic estimation of pulmonary vascular resistance in chronic thromboembolic pulmonary hypertension: utility of right heart Doppler measurements.

Journal Article Echocardiography · 2014 UNLABELLED: The ratio of tricuspid regurgitation velocity divided by the velocity-time integral of right ventricular outflow tract pulsed-wave Doppler tracing (TRV/VTI(RVOT) ) has been used to estimate pulmonary vascular resistance (PVR). However, this met ... Full text Link to item Cite

Riociguat for pulmonary hypertension.

Journal Article N Engl J Med · December 5, 2013 Full text Link to item Cite

Riociguat for pulmonary hypertension.

Journal Article N Engl J Med · December 5, 2013 Full text Link to item Cite

Chronic thromboembolic pulmonary hypertension.

Journal Article Clin Chest Med · December 2013 Chronic thromboembolic pulmonary hypertension (CTEPH) is a disease with high mortality and few treatment options. This article reviews the epidemiology of CTEPH and identifies risk factors for its development. The pathobiology and the progression from thro ... Full text Link to item Cite

Diminished aortic excursion in chronic thromboembolic pulmonary hypertension.

Journal Article Echocardiography · November 2013 BACKGROUND: Although studies have found diminished aortic root motion in left ventricular systolic dysfunction, few data exist on aortic root excursion in isolated right ventricular dysfunction due to chronic thromboembolic pulmonary hypertension (CTEPH). ... Full text Link to item Cite

Pulmonary endarterectomy: recent changes in a single institution's experience of more than 2,700 patients.

Journal Article Ann Thorac Surg · July 2012 BACKGROUND: Chronic thromboembolic pulmonary hypertension (CTEPH) is a known sequela of acute pulmonary embolic disease and yet remains underdiagnosed. Although nonsurgical options for patients with CTEPH have become increasingly available, including pulmo ... Full text Link to item Cite

Evaluation of patients with chronic thromboembolic pulmonary hypertension for pulmonary endarterectomy

Journal Article Pulmonary Circulation · April 1, 2012 Pulmonary hypertension as a result of chronic thromboembolic disease (CTEPH) is potentially curable with pulmonary endarterectomy surgery. Consequently, correctly diagnosing patients with this type of pulmonary hypertension and evaluating these patients wi ... Full text Cite

Efficacy of methylprednisolone in preventing lung injury following pulmonary thromboendarterectomy

Journal Article Chest · January 1, 2012 Background: We sought to determine the efficacy and safety of perioperative treatment with methylprednisolone on the development of lung injury after pulmonary thromboendarterectomy. Methods: This was a randomized, prospective, double-blind, placebo-contro ... Full text Cite

Chronic thromboembolic pulmonary hypertension.

Journal Article Am J Respir Crit Care Med · June 15, 2011 Over the past 4 decades, chronic thromboembolic pulmonary hypertension has evolved from an autopsy curiosity to a potentially correctable form of pulmonary hypertension. Advances in surgical techniques along with the introduction of pulmonary hypertension ... Full text Link to item Cite

Chronic thromboembolic pulmonary hypertension in pediatric patients.

Journal Article J Thorac Cardiovasc Surg · March 2011 OBJECTIVE: Chronic thromboembolic pulmonary hypertension is a rare form of pulmonary hypertension that can lead to progressive right heart failure and death. Pulmonary thromboendarterectomy surgery is the treatment of choice resulting in significant improv ... Full text Link to item Cite

Pulmonary Hypertension

Chapter · December 1, 2010 Full text Cite

Chronic thromboembolic pulmonary hypertension.

Journal Article Clin Chest Med · December 2010 Chronic thromboembolic pulmonary hypertension is one of the few forms of pulmonary hypertension that is surgically curable. It is likely underdiagnosed and must be considered in every patient presenting with pulmonary hypertension to avoid missing the oppo ... Full text Link to item Cite

Embolism after inferior vena cava filter mesh fragmentation.

Journal Article J Vasc Interv Radiol · November 2010 Full text Link to item Cite

Left ventricular strain and strain rate by 2D speckle tracking in chronic thromboembolic pulmonary hypertension before and after pulmonary thromboendarterectomy.

Journal Article Cardiovasc Ultrasound · September 27, 2010 BACKGROUND: Echocardiographic evaluation of left ventricular (LV) strain and strain rate (SR) by 2D speckle tracking may be useful tools to assess chronic thromboembolic pulmonary hypertension (CTEPH) severity as well as response to successful pulmonary th ... Full text Link to item Cite

Chronic thromboembolic pulmonary hypertension

Journal Article Current Treatment Options in Cardiovascular Medicine · April 1, 2010 The pulmonary hypertension (PH) and right heart dysfunction that results from chronic thromboembolic involvement of the pulmonary vascular bed is potentially curable with surgical endarterectomy. Over the past several decades, growing clinical experience h ... Full text Cite

Pulmonary hypertension

Chapter · March 23, 2010 Full text Cite

Inhibition of mTOR attenuates store-operated Ca2+ entry in cells from endarterectomized tissues of patients with chronic thromboembolic pulmonary hypertension.

Journal Article Am J Physiol Lung Cell Mol Physiol · October 2009 Pulmonary vascular remodeling occurs in patients with chronic thromboembolic pulmonary hypertension (CTEPH). One factor contributing to this vascular wall thickening is the proliferation of pulmonary artery smooth muscle cells (PASMC). Store-operated Ca(2+ ... Full text Link to item Cite

Pulmonary hypertensive medical therapy in chronic thromboembolic pulmonary hypertension before pulmonary thromboendarterectomy.

Journal Article Circulation · September 29, 2009 BACKGROUND: The currently recommended treatment for chronic thromboembolic pulmonary hypertension is pulmonary thromboendarterectomy (PTE). No convincing evidence for the use of pulmonary hypertensive medical therapy (PHT) exists in operable candidates. We ... Full text Link to item Cite

Chronic thromboembolic pulmonary hypertension.

Journal Article Semin Respir Crit Care Med · August 2009 The last 4 decades have witnessed dramatic changes in the treatment of patients with pulmonary hypertension. And with the advances in cardiothoracic surgical techniques, selected patients with chronic thromboembolic pulmonary hypertension (CTEPH) are affor ... Full text Link to item Cite

Identification of putative endothelial progenitor cells (CD34+CD133+Flk-1+) in endarterectomized tissue of patients with chronic thromboembolic pulmonary hypertension.

Journal Article Am J Physiol Lung Cell Mol Physiol · June 2009 Chronic thromboembolic pulmonary hypertension (CTEPH) is characterized by a fibrotic thrombus persisting and obliterating the lumen of pulmonary arteries; its pathogenesis remains poorly defined. This study investigates a potential contribution for progeni ... Full text Link to item Cite

Utility of right ventricular Tei index in the noninvasive evaluation of chronic thromboembolic pulmonary hypertension before and after pulmonary thromboendarterectomy.

Journal Article JACC Cardiovasc Imaging · February 2009 OBJECTIVES: We evaluated the utility of tissue Doppler-derived right ventricular (RV) Tei (or myocardial performance) index in patients with chronic thromboembolic pulmonary hypertension (CTEPH) before and after pulmonary thromboendarterectomy (PTE) and as ... Full text Link to item Cite

Silver-coated endotracheal tubes and incidence of ventilator-associated pneumonia: the NASCENT randomized trial.

Journal Article JAMA · August 20, 2008 CONTEXT: Ventilator-associated pneumonia (VAP) causes substantial morbidity. A silver-coated endotracheal tube has been designed to reduce VAP incidence by preventing bacterial colonization and biofilm formation. OBJECTIVE: To determine whether a silver-co ... Full text Link to item Cite

Noninvasive assessment of pulmonary vascular resistance using Doppler tissue imaging of the tricuspid annulus.

Journal Article J Am Soc Echocardiogr · October 2007 BACKGROUND: Pulmonary artery pressure (PAP) and pulmonary vascular resistance (PVR) are important hemodynamic parameters in patients with advanced cardiopulmonary disease. We undertook this study to determine whether Doppler tissue imaging of the tricuspid ... Full text Link to item Cite

Abnormal left ventricular diastolic filling in chronic thromboembolic pulmonary hypertension: true diastolic dysfunction or left ventricular underfilling?

Journal Article J Am Coll Cardiol · March 27, 2007 OBJECTIVES: The purpose of this study was to investigate the cause of abnormal left ventricular (LV) Doppler diastolic filling characteristics in chronic thromboembolic pulmonary hypertension (CTEPH). BACKGROUND: In CTEPH, LV diastolic function often appea ... Full text Link to item Cite

Chronic thromboembolic pulmonary hypertension.

Journal Article Clin Chest Med · March 2007 The description of organized thrombus in major pulmonary arteries can be found in autopsy reports dating back to the late nineteenth and early twentieth centuries. Not until the 1950s was the antemortem diagnosis and clinical syndrome of chronic thrombotic ... Full text Link to item Cite

Cardiac output determination from the arterial pressure wave: clinical testing of a novel algorithm that does not require calibration.

Journal Article J Cardiothorac Vasc Anesth · February 2007 OBJECTIVE: The purpose of this study was to evaluate the accuracy and precision of a novel algorithm that evaluates cardiac output by using arterial pressure waveform characteristics. DESIGN: Prospective, observational study comparing the cardiac output va ... Full text Link to item Cite

Venovenous extracorporeal life support after pulmonary endarterectomy: indications, techniques, and outcomes.

Journal Article Ann Thorac Surg · December 2006 BACKGROUND: Pulmonary endarterectomy is the accepted therapy for thromboembolic pulmonary hypertension. A recognized complication of this surgery is the postoperative development of reperfusion edema, a potentially fatal cause of respiratory failure. Becau ... Full text Link to item Cite

Fibrin derived from patients with chronic thromboembolic pulmonary hypertension is resistant to lysis.

Journal Article Am J Respir Crit Care Med · June 1, 2006 RATIONALE: Although acute pulmonary embolism is epidemiologically associated with chronic thromboembolic pulmonary hypertension, the factors responsible for resistance to thrombolysis and a shift toward vascular remodeling within the pulmonary arteries of ... Full text Link to item Cite

Evaluation of patients for pulmonary endarterectomy.

Journal Article Semin Thorac Cardiovasc Surg · 2006 Chronic thromboembolic obstruction of the pulmonary vascular bed has been increasingly recognized as a treatable form of pulmonary hypertension, with surgery referred to as a pulmonary endarterectomy. Careful evaluation of patients with pulmonary hypertens ... Full text Link to item Cite

Molecular biology of chronic thromboembolic pulmonary hypertension.

Journal Article Semin Thorac Cardiovasc Surg · 2006 Recent efforts have seen major advances in elucidating the mechanisms underlying pulmonary arterial hypertension. However, chronic thromboembolic pulmonary hypertension (CTEPH) often has been excluded from these studies. Consequently, whereas the clinical, ... Full text Link to item Cite

Chronic thromboembolic pulmonary hypertension and pulmonary thromboendarterectomy.

Journal Article Semin Cardiothorac Vasc Anesth · September 2005 Chronic thromboembolic pulmonary hypertension results from incomplete resolution of a pulmonary embolus or from recurrent pulmonary emboli. Its incidence is underappreciated, and it is currently an undertreated phenomenon. Pulmonary thromboendarterectomy i ... Full text Link to item Cite

Massive pulmonary hemorrhage after pulmonary thromboendarterectomy.

Journal Article Anesth Analg · September 2004 Pulmonary thromboendarterectomy, the most common surgical treatment of chronic thromboembolic pulmonary hypertension, is being performed with increasing frequency throughout the world. Massive pulmonary hemorrhage is a potentially fatal complication of thi ... Full text Link to item Cite

Chronic thromboembolic pulmonary hypertension.

Journal Article Cardiol Clin · August 2004 During the past 2 decades, there has been a steady rise in the number of patients with chronic thromboembolic pulmonary hypertension (CTEPH) undergoing surgery and in the number of programs worldwide dedicated to the diagnosis and management of this patien ... Full text Link to item Cite

Deep hypothermic circulatory arrest and the femoral-to-radial arterial pressure gradient.

Journal Article J Cardiothorac Vasc Anesth · April 2004 OBJECTIVES: To determine the femoral-to-radial arterial pressure gradient, as well as the factors associated with them, in patients receiving cardiopulmonary bypass (CPB) with profound hypothermia and circulatory arrest. DESIGN: Retrospective automated hem ... Full text Link to item Cite

Continuous intravenous epoprostenol for chronic thromboembolic pulmonary hypertension.

Journal Article Eur Respir J · April 2004 Pathophysiological findings in chronic thromboembolic pulmonary hypertension (CTEPH) have suggested that a secondary small vessel arteriopathy may contribute to the haemodynamic impairment observed in these patients. It was hypothesised that this element o ... Full text Link to item Cite

Pulmonary endarterectomy: experience and lessons learned in 1,500 cases.

Journal Article Ann Thorac Surg · November 2003 BACKGROUND: The incidence of pulmonary hypertension resulting from chronic thrombotic occlusion of the pulmonary arteries is significantly underestimated. Although medical therapy for the condition is supportive only, surgical therapy is curative. Our pulm ... Full text Link to item Cite

Chronic thromboembolic pulmonary hypertension

Journal Article Seminars in Respiratory and Critical Care Medicine · June 1, 2003 Over the past 4 decades, chronic thromboembolic pulmonary hypertension has evolved from an autopsy curiosity to a potentially correctable form of pulmonary hypertension. Approximately 2500 thromboendarterectomy procedures have now been performed worldwide ... Full text Cite

Balloon angioplasty and stenting of multiple intralobar pulmonary arterial stenoses in adult patients.

Journal Article Catheter Cardiovasc Interv · February 2003 Balloon angioplasty and stent placement for pulmonary arterial stenoses in children are well-established therapies. In contrast, management of isolated peripheral pulmonary arterial stenoses in adults remains relatively unexplored. Four women (ages 18-63 y ... Full text Link to item Cite

An unusual case of pulmonary artery catheter malfunction.

Journal Article Anesth Analg · August 2002 Sudden loss of thermodilution or temperature-monitoring capabilities of an indwelling pulmonary artery catheter may indicate significant damage to the catheter, possibly leading to electrical hazard and infection risk. Blood appearing at the electrical con ... Full text Link to item Cite

Correlation of left ventricular diastolic filling characteristics with right ventricular overload and pulmonary artery pressure in chronic thromboembolic pulmonary hypertension.

Journal Article J Am Coll Cardiol · July 17, 2002 OBJECTIVES: This study was designed to determine a quantitative relationship between right ventricular (RV) pressure overload and left ventricular (LV) diastolic filling characteristics in patients with chronic thromboembolic pulmonary hypertension (CTEPH) ... Full text Link to item Cite

Chronic thromboembolic pulmonary hypertension.

Journal Article N Engl J Med · November 15, 2001 Full text Link to item Cite

Parathyroid hormone-related protein and lung injury after pulmonary thromboendarterectomy.

Journal Article Regul Pept · October 15, 2001 Parathyroid hormone-related protein (PTHrP) is an autocrine growth and differentiation factor for alveolar type II epithelial cells. Type II cells secrete pulmonary surfactant and are pluripotent cells with a role in alveolar epithelial repair after lung i ... Full text Link to item Cite

Chronic thromboembolic pulmonary hypertension.

Journal Article Clin Chest Med · September 2001 Remarkable advances have occurred over the past 2 decades in the diagnostic approach, surgical management, and postoperative care of patients afflicted with chronic thromboembolic pulmonary hypertension. Despite these advances, a great deal needs to be ach ... Full text Link to item Cite

Pulmonary thromboendarterectomy combined with other cardiac operations: indications, surgical approach, and outcome.

Journal Article Ann Thorac Surg · July 2001 BACKGROUND: Patients with pulmonary hypertension due to chronic thromboembolic disease benefit from pulmonary thromboendarterectomy. A subset of these patients present with concomitant coronary or valvular disease. METHODS: From July 1990 to July 2000, 90 ... Full text Link to item Cite

Fatal paradoxic embolism occurring during IVC filter insertion in a patient with chronic pulmonary thromboembolic disease.

Journal Article J Vasc Interv Radiol · June 2001 A patient diagnosed with chronic thromboembolic disease experienced a fatal intraprocedural paradoxic embolism during inferior vena cava (IVC) filter insertion. The frequency of patent intra-atrial shunts in patients with chronic thromboembolic disease is ... Full text Link to item Cite

Dilation of the coronary sinus on echocardiogram: prevalence and significance in patients with chronic pulmonary hypertension.

Journal Article J Am Soc Echocardiogr · January 2001 BACKGROUND: Although rarely seen in healthy patients, the coronary sinus (CS) is often visualized on echocardiography in patients with right-sided heart disease. However, the prevalence of this finding and its relation to right-sided heart structure and pr ... Full text Link to item Cite

"High probability" perfusion lung scans in pulmonary venoocclusive disease.

Journal Article Am J Respir Crit Care Med · November 2000 "High-probability" ventilation/perfusion (V/Q) lung scans generally indicate proximal pulmonary arterial occlusion by thromboemboli or, rarely, other processes such as tumors, fibrosing mediastinitis, or vasculitis. In this report we describe three patient ... Full text Link to item Cite

The use of cylexin (CY-1503) in prevention of reperfusion lung injury in patients undergoing pulmonary thromboendarterectomy.

Journal Article Am J Respir Crit Care Med · July 2000 Pulmonary thromboendartectomy (PTE) for chronic thromboembolic pulmonary hypertension may be complicated by reperfusion lung injury. This has previously been demonstrated to be neutrophil-mediated. We postulated that blocking selectin-mediated adhesion of ... Full text Link to item Cite

Successful pulmonary thromboendarterectomy in a patient with Klippel-Trenaunay syndrome.

Journal Article Chest · May 2000 Klippel-Trenaunay syndrome (KTS) is a congenital disorder characterized by a triad of cutaneous vascular nevi, soft tissue or bony hypertrophy, and varicose veins or venous malformations involving one or more extremities. An incidence of venous thromboembo ... Full text Link to item Cite

Predictors of patient response to pulmonary thromboendarterectomy.

Journal Article AJR Am J Roentgenol · February 2000 OBJECTIVE: We sought to identify imaging features that help predict surgical success in patients undergoing thromboendarterectomy. MATERIALS AND METHODS: Thirty-nine consecutive patients who underwent pulmonary angiography and thromboendarterectomy during ... Full text Link to item Cite

Chronic thromboembolic pulmonary hypertension

Journal Article Seminars in Respiratory and Critical Care Medicine · January 1, 2000 Under most circumstances, chronic thromboembolic pulmonary hypertension represents a correctable form of pulmonary hypertension. Approximately 1500 thromboendarterectomy procedures have now been performed worldwide. Mortality rates reported by established ... Full text Cite

Reoperative pulmonary thromboendarterectomy.

Journal Article Ann Thorac Surg · November 1999 BACKGROUND: Recurrent symptomatic pulmonary hypertension is uncommon after primary pulmonary thromboendarterectomy (PTE). We reviewed our experience with patients undergoing repeat PTE to determine the risk factors for recurrent disease, and the selection ... Full text Link to item Cite

Atrial septostomy as a bridge to lung transplantation in patients with severe pulmonary hypertension.

Journal Article Am J Cardiol · September 15, 1999 Long waiting times for lung transplantation have limited the survival of patients with advanced pulmonary hypertension. Atrial septostomy has been used in this group of patients in an attempt to prolong survival. We evaluated the results of atrial septosto ... Full text Link to item Cite

Long-term outcome after pulmonary thromboendarterectomy.

Journal Article Am J Respir Crit Care Med · August 1999 This study evaluated long-term outcome of pulmonary thromboendarterectomy (PTE) in patients with chronic thromboembolic pulmonary hypertension (CTEPH). Survival, functional status, quality of life, health care utilization, and relationships between these p ... Full text Link to item Cite

Evaluation of patients with suspected chronic thromboembolic pulmonary hypertension.

Journal Article Semin Thorac Cardiovasc Surg · April 1999 Chronic thromboembolic pulmonary hypertension (CTEPH) can be a difficult diagnosis to establish, typically requiring a high index of suspicion on the part of the clinician when challenged by a patient reporting exertional dyspnea. The importance of this di ... Full text Link to item Cite

Historical perspective: surgery for chronic thromboembolic disease.

Journal Article Semin Thorac Cardiovasc Surg · April 1999 Obstruction of major pulmonary vessels with organized thromboemboli is a rare sequelae of acute pulmonary embolic disease. Depending on the extent and duration of vascular occlusion, patients experiencing this unusual disorder may develop significant pulmo ... Full text Link to item Cite

Postoperative management of the patient undergoing pulmonary thromboendarterectomy.

Journal Article Semin Thorac Cardiovasc Surg · April 1999 The postoperative course of the patient undergoing pulmonary thromboendarterectomy poses a unique series of challenges in terms of ventilatory care and hemodynamic management. Experience, cooperation, and interaction are necessary among the various discipl ... Full text Link to item Cite

Outcome after pulmonary thromboendarterectomy.

Journal Article Semin Thorac Cardiovasc Surg · April 1999 Pulmonary thromboendarterectomy (PTE) surgery is an effective treatment for the majority of patients with chronic thromboembolic pulmonary hypertension (CTEPH), with an acceptable mortality rate. The immediate outcome after PTE has repeatedly shown a drama ... Full text Link to item Cite

Successful pulmonary thromboendarterectomy in two patients with sickle cell disease.

Journal Article Am J Respir Crit Care Med · May 1998 Patients with sickle cell disease have been reported to have an increased risk of thromboembolism and pulmonary hypertension. Some of these patients may benefit from pulmonary thromboendarterectomy (PTE), a procedure that requires profound hypothermia, car ... Full text Link to item Cite

Chronic thromboembolism: diagnosis with helical CT and MR imaging with angiographic and surgical correlation.

Journal Article Radiology · September 1997 PURPOSE: To evaluate the accuracy of identification of central and segmental chronic thromboembolic disease on helical computed tomographic (CT) scans and on magnetic resonance (MR) images. MATERIALS AND METHODS: Radiologic findings in 55 patients suspecte ... Full text Link to item Cite

Right ventricular pathology in chronic pulmonary hypertension.

Journal Article Am J Cardiol · September 1, 1996 Right ventricular free wall biopsy specimens in 40 patients undergoing surgery for relief of chronic thromboembolic pulmonary hypertension were normal in 5%, disclosed only myocyte hypertrophy in 80%, mild focal fibrosis in 12.5%, and myocarditis in 2.5%. ... Full text Link to item Cite

Parenchymal scarring is associated with restrictive spirometric defects in patients with chronic thromboembolic pulmonary hypertension.

Journal Article Chest · August 1996 UNLABELLED: The finding of a restrictive pulmonary defect may divert clinicians from considering the diagnosis of chronic thromboembolic pulmonary hypertension because lung volumes are usually normal in this disorder. We have, however, encountered a signif ... Full text Link to item Cite

Unilateral pulmonary artery thrombotic occlusion: is distal arteriopathy a consequence?

Journal Article Am J Respir Crit Care Med · August 1996 The characteristics and postoperative outcomes of a unique group of eleven patients with total unilateral pulmonary artery (PA) thromboembolic occlusion were compared with those of some 400 patients who underwent bilateral thromboendarterectomies during th ... Full text Link to item Cite

Accuracy of high-resolution CT in identifying chronic pulmonary thromboembolic disease.

Journal Article AJR Am J Roentgenol · June 1996 OBJECTIVE: The aims of this study were to determine the reliability of the high-resolution CT (HRCT) appearance of the lung parenchyma in distinguishing patients with chronic pulmonary thromboembolism (CPTE) from those with other pulmonary diseases and to ... Full text Link to item Cite

Pulsed delivery of inhaled nitric oxide to patients with primary pulmonary hypertension: An ambulatory delivery system and initial clinical tests

Journal Article Chest · January 1, 1996 Background: Inhaled nitric oxide (NO) has been shown to be a selective pulmonary vasodilator in certain patients with primary pulmonary hypertension (PPH). Objectives: The purpose of this study was to design and test a system for delivery of NO to awaken, ... Full text Cite

Accuracy of contrast-enhanced magnetic resonance angiography in chronic thromboembolic disease.

Journal Article Acad Radiol · January 1996 RATIONALE AND OBJECTIVES: We evaluated the accuracy of contrast-enhanced magnetic resonance (MR) angiography in demonstrating the findings of chronic pulmonary thromboembolism (CPTE) compared with conventional pulmonary angiography. METHODS: We examined 18 ... Full text Link to item Cite

Unilateral pulmonary artery thromboembolic occlusion in patients: Is distal arteriopathy a consequence?

Journal Article Journal of Investigative Medicine · January 1, 1996 The characteristics and post-operative outcomes of eleven patients with total unilateral (UNI)pulmonary artery (PA) thromboembolic occlusion were compared with those of some 600 patients who underwent bilateral (BI) thromboendarterectomies during the same ... Cite

Lupus anticoagulant, heparin use, and thrombocytopenia in patients with chronic thromboembolic pulmonary hypertension: a preliminary report.

Journal Article Am J Med · October 1995 PURPOSE: An increased occurrence of thrombotic events has been described in patients exhibiting a lupus anticoagulant (LA). In patients with chronic, major vessel thromboembolic pulmonary hypertension, not only has there been a relatively high frequency of ... Full text Link to item Cite

Pulmonary hypertension and cor pulmonale.

Journal Article Curr Opin Pulm Med · July 1995 An ever-expanding body of information has provided new insights into the pathophysiologic mechanisms contributing to pulmonary hypertensive disease. The pulmonary endothelial cell has been shown to have a central role in both the maintenance of normal vasc ... Link to item Cite

Large vessel pulmonary arteritis mimicking chronic thromboembolic disease.

Journal Article Am J Respir Crit Care Med · July 1995 Chronic obstruction of pulmonary arteries can be due to a variety of disease processes, including chronic thromboembolic disease, fibrosing mediastinitis, or neoplasia. Large vessel arteritis is another unusual cause of pulmonary artery obstruction and can ... Full text Link to item Cite

Chronic thromboembolic pulmonary hypertension.

Journal Article Clin Chest Med · June 1995 Chronic, major-vessel thromboembolic disease represents a potentially correctable form of pulmonary hypertension. A thorough understanding of the unique problems associated with each aspect of care in these patients is essential to ensure a minimal periope ... Link to item Cite

Intravascular bronchioloalveolar tumor of the lung presenting as pulmonary thromboembolic disease and pulmonary hypertension.

Journal Article Arch Pathol Lab Med · March 1995 Intravascular bronchioloalveolar tumor, the pulmonary counterpart of epithelioid hemangioendothelioma, typically presents as bilateral pulmonary nodules in young women. We report a case of intravascular bronchioloalveolar tumor that clinically mimicked acu ... Link to item Cite

Methylphenidate in the 'hard to wean' patient.

Journal Article J Psychosom Res · January 1995 Patients on mechanical ventilation are occasionally hard to wean because of fatigue and/or depression. It is difficult to diagnose depression in this population, and treatment with traditional antidepressants has too slow an onset to be useful. Two cases a ... Full text Link to item Cite

Chronic pulmonary thromboembolism: detection of regional hypoperfusion with CT.

Journal Article Radiology · May 1994 PURPOSE: To study the relationship of regional hypoperfusion and areas of decreased lung attenuation on computed tomographic (CT) scans of patients with chronic pulmonary thromboembolism. MATERIALS AND METHODS: Preoperative CT scans of five patients (four ... Full text Link to item Cite

Resolution of vascular steal after pulmonary thromboendarterectomy.

Journal Article Chest · November 1993 Patients who undergo thromboendarterectomy for relief of chronic, major-vessel thromboembolic pulmonary hypertension (CT-E PH) offer a unique opportunity to evaluate potential resolution of hypertensive lesions in the small, nonelastic pulmonary arteries. ... Full text Link to item Cite

Experience and results with 150 pulmonary thromboendarterectomy operations over a 29-month period.

Journal Article J Thorac Cardiovasc Surg · July 1993 A program to alleviate chronic, major vessel thromboembolic pulmonary hypertension by pulmonary thromboendarterectomy was initiated at this institution in 1970. Multiple evolutionary changes in the diagnostic evaluation, surgical approach, and postoperativ ... Link to item Cite

Chronic thromboembolic pulmonary hypertension: clinical picture and surgical treatment.

Journal Article Eur Respir J · March 1992 Chronic, major vessel thromboembolic pulmonary hypertension (CTEPH), is an uncommon condition which, in the past, was an autopsy curiosity. Advances in diagnostic approaches, surgical techniques and postoperative management have transformed this disorder i ... Link to item Cite

Chronic major-vessel thromboembolic pulmonary artery obstruction: appearance at angiography.

Journal Article Radiology · February 1992 The pulmonary angiograms of 250 patients evaluated for chronic thromboembolic pulmonary hypertension were reviewed. Pulmonary thromboendarterectomy was performed in each of these individuals, and the surgical findings were correlated with abnormal angiogra ... Full text Link to item Cite

Epicardial activation and repolarization patterns in patients with right ventricular hypertrophy.

Journal Article Circulation · January 1991 To map global epicardial repolarization patterns and test the "SI" model of T wave generation, the patterns of epicardial activation and repolarization in patients with chronic pulmonary thromboembolism and right ventricular hypertrophy were studied by com ... Full text Link to item Cite

Pulmonary vascular steal in chronic thromboembolic pulmonary hypertension.

Conference Chest · December 1990 After pulmonary thromboendarterectomy, performed for relief of chronic thromboembolic pulmonary hypertension, perfusion lung scans have frequently disclosed new perfusion defects in segments served by undissected pulmonary arteries. Our hypotheses were tha ... Full text Link to item Cite

Risk factors for pulmonary thromboendarterectomy.

Conference J Thorac Cardiovasc Surg · April 1990 Pulmonary thromboendarterectomy is being performed with increasing frequency for incapacitating pulmonary hypertension caused by chronic large-vessel pulmonary embolism. However, patient-related risk factors and procedural complications associated with mor ... Link to item Cite

Perfusion techniques of profound hypothermia and circulatory arrest for pulmonary thromboendarterectomy

Journal Article Journal of Extra-Corporeal Technology · January 1, 1990 One hundred ninety-five patients with the diagnosis of chronic pulmonary thromboembolic pulmonary hypertension have been operated on utilizing a standardized protocol involving profound hypothermia and circulatory arrest. A small subgroup, nine, were ident ... Cite