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William Majoros

Assistant Professor of Biostatistics & Bioinformatics
Biostatistics & Bioinformatics, Division of Integrative Genomics
Duke Box 103854, Durham, NC 27710
101 Science Drive, 2187 CIEMAS, Research Drive, Durham, NC 27708

Research Interests


  • Probabilistic machine learning
  • Bayesian graphical models
  • Structured prediction
  • Interpretation/prioritization of genetic variants in disease
  • RNA splicing
  • Gene regulation
  • Computational linguistics - formal grammars and parsing
  • Syntactic structure and memetic evolution in complex bird song

Selected Grants


Computational Methods for Investigating the Genetics of Gene Regulation

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2023 - 2028

High-Throughput Functional Annotation of Gene Regulatory Elements and Variants Critical to Complex Cellular Phenotypes

ResearchCo Investigator · Awarded by National Institutes of Health · 2021 - 2026

Design, prediction, and prioritization of systematic perturbations of the human genome

ResearchCo-Principal Investigator · Awarded by National Human Genome Research Institute · 2021 - 2026

The Duke FUNCTION Center: Pioneering the comprehensive identification of combinatorial noncoding causes of disease

ResearchCo Investigator · Awarded by National Human Genome Research Institute · 2020 - 2025

Quantifying the genetic diversity of human regulatory element activity

ResearchBioinformatician I · Awarded by National Institutes of Health · 2019 - 2024

Identifying Pathogenic Non-Coding Mutations in Rare Mendelian Disease

ResearchBioinformatician II · Awarded by National Institutes of Health · 2019 - 2022

Decoding and Reprogramming the Corticosteroid Transcriptional Regulatory Network

ResearchResearch Associate · Awarded by National Institutes of Health · 2015 - 2018

Genetics and Genomics of Maternal Glycemia During Pregnancy

ResearchResearch Assistant · Awarded by Northwestern University · 2013 - 2018

Genetics and Evolution of Fetal Human Fat Accretion During Development

ResearchResearch Assistant · Awarded by Northwestern University · 2013 - 2018

University of Utah

ResearchResearch Assistant · Awarded by University of Utah · 2017 - 2018

EAGER: Graph-based Genome Annotation and Analyses for Plant Genomes

ResearchResearch Assistant · Awarded by University of Utah · 2016 - 2017

Modeling the structure & evolution of regulatory regions in eukaryotic genomes

ResearchBiostatistician · Awarded by National Institutes of Health · 2007 - 2013

Function of alpha herpesvirus microRNAs

ResearchBioinformatics Specialist · Awarded by National Institutes of Health · 2010 - 2011