W Daniel Stamer
Joseph A.C. Wadsworth Professor of Ophthalmology
Current Appointments & Affiliations
- Joseph A.C. Wadsworth Professor of Ophthalmology, Ophthalmology, Glaucoma, Ophthalmology 2014
- Professor of Ophthalmology, Ophthalmology, Glaucoma, Ophthalmology 2011
- Professor of Biomedical Engineering, Biomedical Engineering, Pratt School of Engineering 2013
Contact Information
- 2608 Erwin Rd, Box 148-145, Durham, NC 27705
- Duke Eye Center, DUMC 3802, Aeri 4th Floor, Durham, NC 27710
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william.stamer@duke.edu
(919) 684-3745
- Background
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Education, Training, & Certifications
- Professor, Department Of Ophthalmology And Pharmacology, University of Arizona College of Medicine 2006 - 2011
- Associate Professor, Departments Of Ophthalmology And Pharmacology, University of Arizona College of Medicine 2003 - 2006
- Assistant Professor, Departmentsof Ophthalmology And Pharmacology, University of Arizona College of Medicine 1999 - 2003
- Postdoctoral Fellow, Department Of Ophthalmology, Duke University School of Medicine 1997 - 1998
- Postdoctoral Fellow, Physiology And Pharmacology/Toxicology Departments, University of Arizona College of Medicine 1996 - 1997
- Graduate Research Assistant, Pharmacology And Toxicology Department, University of Arizona College of Medicine 1993 - 1996
- Ph.D., University of Arizona 1996
- B.S., University of Arizona 1990
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Duke Appointment History
- Instructor Temporary in the Department of Ophthalmology, Ophthalmology, Clinical Science Departments 2011
- Research
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Selected Grants
- Quantitative assessment of glaucomatous conventional outflow dynamics awarded by National Institutes of Health 2019 - 2023
- eNOS-Dependent Mechanoregulation of Intraocular Pressure awarded by National Institutes of Health 2012 - 2021
- eNOS-Dependent Mechanoregulation of Intraocular Pressure awarded by National Institutes of Health 2012 - 2021
- Testing effect of sustained release vs cyclic exposure of bimatoprost on MMP/TIMP/ECM expression by outflow cells 2018 - 2020
- Caveolae-based mechanosensors for conventional outflow regulation 2018 - 2020
- Caveolin-mediated mechanosensation in Schlemm¿s canal endothelia 2019
- Netarsudil effects on outflow tissue behavior in model of steroid-induced glaucoma 2017 - 2019
- Efficacy testing of BZ371C on outflow facility in mouse eyes 2019
- Aerpio RSA 2018 - 2019
- Caveolae-based mechanosensors for conventional outflow regulation 2018 - 2019
- The Mechanical Basis of Primary Open Angle Glaucoma awarded by Northwestern University 2011 - 2019
- Basic Science Catalyzing Treatments for Glaucoma awarded by National Institutes of Health 2017 - 2018
- Role of non-coding RNAs in glaucomatous outflow resistance dysregulation 2016 - 2018
- The Role of Exosomes in Dry AMD 2015 - 2018
- MicroRNA-directed modulation of intraocular pressure awarded by National Institutes of Health 2013 - 2018
- OCT measurement of TM/SC stiffness in living mice 2015 - 2017
- Duke-MiS Eye Tissue Bank and Donor Registry Project Duke Eye Tissue Bank/Registry 2016 - 2017
- sGC stimulators and trabecular meshwork biology 2016 - 2017
- Trabodenoson and conventional outflow function 2015 - 2017
- Role of Exosomes in Glaucomatous Lamina Cribrosa Remodeling 2016 - 2017
- Mechanisms in Exfoliation Glaucoma: Effect of Genetic Risk Variants and Ocular Cell Stressors on LOXL1 Expression 2015 - 2016
- Shear stress regulation of barrier function in Schlemm's canal awarded by National Institutes of Health 2014 - 2016
- Lysosomal enzymes, Glycosaminoglycans and Outflow Pathway Physiology 2015 - 2016
- Ocular Pharmacology and Therapeutics Conference awarded by National Institutes of Health 2014 - 2015
- sGC stimulator effects on outflow facility 2014 - 2015
- Effects of rho kinase inhibitors on outflow facility and PEFL in human donor eyes 2015
- Effects of rho kinase inhibitors on outflow facility and PEFL in human donor eyes 2014 - 2015
- Exosomal RNAs and Aqueous Humor Dynamics in Exfoliation Glaucoma 2014
- Testing anti-S1P/LPA biologicals in living mice 2013 - 2014
- Aquaporin 1 And Aqueous Humor Outflow In The Eye awarded by National Institutes of Health 1998 - 1999
- Aquaporin And Aqueous Humor Outflow In The Human Eye awarded by National Institutes of Health 1997 - 1999
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Industry Relationships
- Aerie Pharmaceuticals, Inc.
- Aerpio Therapeutics
- Allergan, Inc.
- Ascent Bio-Nano Technologies, Inc.
- Glauconix
- Regeneron Pharmaceuticals
- Publications & Artistic Works
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Selected Publications
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Academic Articles
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Woodward, David F., Jenny W. Wang, Robert A. Coleman, Amanda J. Woodrooffe, Kenneth L. Clark, W Daniel Stamer, Guoxian Tao, Shan Fan, and Carol B. Toris. “A Highly Effective and Ultra-Long-Acting Anti-Glaucoma Drug, with a Novel Periorbital Delivery Method..” J Ocul Pharmacol Ther 35, no. 5 (June 2019): 265–77. https://doi.org/10.1089/jop.2018.0126.Full Text Link to Item
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Itakura, Tatsuo, Andrew Webster, Shravan K. Chintala, Yuchen Wang, Jose M. Gonzalez, J. C. Tan, Janice A. Vranka, et al. “GPR158 in the Visual System: Homeostatic Role in Regulation of Intraocular Pressure..” J Ocul Pharmacol Ther 35, no. 4 (May 2019): 203–15. https://doi.org/10.1089/jop.2018.0135.Full Text Link to Item
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Vahabikashi, Amir, Chan Young Park, Kristin Perkumas, Zhiguo Zhang, Emily K. Deurloo, Huayin Wu, David A. Weitz, et al. “Probe Sensitivity to Cortical versus Intracellular Cytoskeletal Network Stiffness..” Biophys J 116, no. 3 (February 5, 2019): 518–29. https://doi.org/10.1016/j.bpj.2018.12.021.Full Text Link to Item
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Sherwood, Joseph M., W Daniel Stamer, and Darryl R. Overby. “A model of the oscillatory mechanical forces in the conventional outflow pathway..” J R Soc Interface 16, no. 150 (January 31, 2019). https://doi.org/10.1098/rsif.2018.0652.Full Text Link to Item
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Li, Guorong, Chanyoung Lee, Vibhuti Agrahari, Ke Wang, Iris Navarro, Joseph M. Sherwood, Karen Crews, et al. “In vivo measurement of trabecular meshwork stiffness in a corticosteroid-induced ocular hypertensive mouse model..” Proc Natl Acad Sci U S A 116, no. 5 (January 29, 2019): 1714–22. https://doi.org/10.1073/pnas.1814889116.Full Text Link to Item
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Dillinger, Andrea E., Michaela Guter, Franziska Froemel, Gregor R. Weber, Kristin Perkumas, W Daniel Stamer, Andreas Ohlmann, Rudolf Fuchshofer, and Miriam Breunig. “Intracameral Delivery of Layer-by-Layer Coated siRNA Nanoparticles for Glaucoma Therapy..” Small 14, no. 50 (December 2018). https://doi.org/10.1002/smll.201803239.Full Text Link to Item
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Klingeborn, Mikael, W Michael Dismuke, Nikolai P. Skiba, Una Kelly, W Daniel Stamer, and Catherine Bowes Rickman. “Author Correction: Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers..” Sci Rep 8, no. 1 (November 20, 2018). https://doi.org/10.1038/s41598-018-35542-w.Full Text Link to Item
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Stamer, W Daniel, Andrew M. Williams, Stephen Pflugfelder, and Sarah E. Coupland. “Accessibility to and Quality of Human Eye Tissue for Research: A Cross-Sectional Survey of ARVO Members..” Invest Ophthalmol Vis Sci 59, no. 12 (October 1, 2018): 4783–92. https://doi.org/10.1167/iovs.18-25319.Full Text Link to Item
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McDonnell, Fiona, W Michael Dismuke, Darryl R. Overby, and W Daniel Stamer. “Pharmacological regulation of outflow resistance distal to Schlemm's canal..” Am J Physiol Cell Physiol 315, no. 1 (July 1, 2018): C44–51. https://doi.org/10.1152/ajpcell.00024.2018.Full Text Link to Item
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Keller, Kate E., Sanjoy K. Bhattacharya, Theresa Borrás, Thomas M. Brunner, Sunee Chansangpetch, Abbott F. Clark, W Michael Dismuke, et al. “Consensus recommendations for trabecular meshwork cell isolation, characterization and culture..” Exp Eye Res 171 (June 2018): 164–73. https://doi.org/10.1016/j.exer.2018.03.001.Full Text Link to Item
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Khaled, Mariam Lofty, Yelena Bykhovskaya, Sarah E. R. Yablonski, Hanzhou Li, Michelle D. Drewry, Inas F. Aboobakar, Amy Estes, et al. “Differential Expression of Coding and Long Noncoding RNAs in Keratoconus-Affected Corneas..” Invest Ophthalmol Vis Sci 59, no. 7 (June 1, 2018): 2717–28. https://doi.org/10.1167/iovs.18-24267.Full Text Open Access Copy Link to Item
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Wang, Ke, Guorong Li, A Thomas Read, Iris Navarro, Ashim K. Mitra, W Daniel Stamer, Todd Sulchek, and C Ross Ethier. “The relationship between outflow resistance and trabecular meshwork stiffness in mice..” Sci Rep 8, no. 1 (April 11, 2018). https://doi.org/10.1038/s41598-018-24165-w.Full Text Link to Item
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Drewry, Michelle D., Pratap Challa, John G. Kuchtey, Iris Navarro, Inas Helwa, Yanzhong Hu, Hongmei Mu, W Daniel Stamer, Rachel W. Kuchtey, and Yutao Liu. “Differentially expressed microRNAs in the aqueous humor of patients with exfoliation glaucoma or primary open-angle glaucoma..” Hum Mol Genet 27, no. 7 (April 1, 2018): 1263–75. https://doi.org/10.1093/hmg/ddy040.Full Text Link to Item
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Beit-Yannai, Elie, Saray Tabak, and W Daniel Stamer. “Physical exosome:exosome interactions..” J Cell Mol Med 22, no. 3 (March 2018): 2001–6. https://doi.org/10.1111/jcmm.13479.Full Text Link to Item
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Johnson, William M., Laura K. Finnegan, Michael A. Hauser, and W Daniel Stamer. “lncRNAs, DNA Methylation, and the Pathobiology of Exfoliation Glaucoma..” J Glaucoma 27, no. 3 (March 2018): 202–9. https://doi.org/10.1097/IJG.0000000000000711.Full Text Link to Item
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Snider, Eric J., R Taylor Vannatta, Lisa Schildmeyer, W Daniel Stamer, and C Ross Ethier. “Characterizing differences between MSCs and TM cells: Toward autologous stem cell therapies for the glaucomatous trabecular meshwork..” J Tissue Eng Regen Med 12, no. 3 (March 2018): 695–704. https://doi.org/10.1002/term.2488.Full Text Link to Item
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Klingeborn, Mikael, W Daniel Stamer, and Catherine Bowes Rickman. “Polarized Exosome Release from the Retinal Pigmented Epithelium..” Adv Exp Med Biol 1074 (2018): 539–44. https://doi.org/10.1007/978-3-319-75402-4_65.Full Text Link to Item
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Li, Guorong, Karen Y. Torrejon, Andrea M. Unser, Feryan Ahmed, Iris D. Navarro, Rudolf A. Baumgartner, David S. Albers, and W Daniel Stamer. “Trabodenoson, an Adenosine Mimetic With A1 Receptor Selectivity Lowers Intraocular Pressure by Increasing Conventional Outflow Facility in Mice..” Invest Ophthalmol Vis Sci 59, no. 1 (January 1, 2018): 383–92. https://doi.org/10.1167/iovs.17-23212.Full Text Link to Item
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Aliancy, Joah, W Daniel Stamer, and Barbara Wirostko. “A Review of Nitric Oxide for the Treatment of Glaucomatous Disease..” Ophthalmol Ther 6, no. 2 (December 2017): 221–32. https://doi.org/10.1007/s40123-017-0094-6.Full Text Link to Item
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Shan, Sze Wan, Chi Wai Do, Thomas Chuen Lam, Ricky Pak Wing Kong, King Kit Li, Ka Man Chun, William Daniel Stamer, and Chi Ho To. “New Insight of Common Regulatory Pathways in Human Trabecular Meshwork Cells in Response to Dexamethasone and Prednisolone Using an Integrated Quantitative Proteomics: SWATH and MRM-HR Mass Spectrometry..” J Proteome Res 16, no. 10 (October 6, 2017): 3753–65. https://doi.org/10.1021/acs.jproteome.7b00449.Full Text Link to Item
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McKay, Brian S., Ronald M. Lynch, and W Daniel Stamer. “Comment on "Identification of Novel G Protein-Coupled Receptor 143 Ligands as Pharmacologic Tools for Investigating X-Linked Ocular Albinism"..” Invest Ophthalmol Vis Sci 58, no. 11 (September 1, 2017): 4733–34. https://doi.org/10.1167/iovs.17-22660.Full Text Link to Item
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Muenster, Stefan, Wolfgang S. Lieb, Gregor Fabry, Kaitlin N. Allen, Shivani S. Kamat, Ann H. Guy, Ana C. Dordea, et al. “The Ability of Nitric Oxide to Lower Intraocular Pressure Is Dependent on Guanylyl Cyclase..” Invest Ophthalmol Vis Sci 58, no. 11 (September 1, 2017): 4826–35. https://doi.org/10.1167/iovs.17-22168.Full Text Link to Item
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Agrahari, Vibhuti, Guorong Li, Vivek Agrahari, Iris Navarro, Kristin Perkumas, Abhirup Mandal, W Daniel Stamer, and Ashim K. Mitra. “Pentablock copolymer dexamethasone nanoformulations elevate MYOC: in vitro liberation, activity and safety in human trabecular meshwork cells..” Nanomedicine (Lond) 12, no. 16 (August 2017): 1911–26. https://doi.org/10.2217/nnm-2017-0140.Full Text Link to Item
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Chang, Jason Y. H., Lesley W. Chow, W Michael Dismuke, C Ross Ethier, Molly M. Stevens, W Daniel Stamer, and Darryl R. Overby. “Peptide-Functionalized Fluorescent Particles for In Situ Detection of Nitric Oxide via Peroxynitrite-Mediated Nitration..” Adv Healthc Mater 6, no. 16 (August 2017). https://doi.org/10.1002/adhm.201700383.Full Text Link to Item
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Klingeborn, Mikael, W Michael Dismuke, Nikolai P. Skiba, Una Kelly, W Daniel Stamer, and Catherine Bowes Rickman. “Directional Exosome Proteomes Reflect Polarity-Specific Functions in Retinal Pigmented Epithelium Monolayers..” Sci Rep 7, no. 1 (July 7, 2017). https://doi.org/10.1038/s41598-017-05102-9.Full Text Open Access Copy Link to Item
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Klingeborn, Mikael, W Michael Dismuke, Catherine Bowes Rickman, and W Daniel Stamer. “Roles of exosomes in the normal and diseased eye..” Prog Retin Eye Res 59 (July 2017): 158–77. https://doi.org/10.1016/j.preteyeres.2017.04.004.Full Text Link to Item
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Roddy, Gavin W., Kimberly B. Viker, Nelson S. Winkler, Cindy K. Bahler, Bradley H. Holman, David Sheikh-Hamad, Uttio Roy Chowdhury, W Daniel Stamer, and Michael P. Fautsch. “Stanniocalcin-1 Is an Ocular Hypotensive Agent and a Downstream Effector Molecule That Is Necessary for the Intraocular Pressure-Lowering Effects of Latanoprost..” Invest Ophthalmol Vis Sci 58, no. 5 (May 1, 2017): 2715–24. https://doi.org/10.1167/iovs.16-21004.Full Text Link to Item
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Stamer, W Daniel, and Abbot F. Clark. “The many faces of the trabecular meshwork cell..” Exp Eye Res 158 (May 2017): 112–23. https://doi.org/10.1016/j.exer.2016.07.009.Full Text Link to Item
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Stamer, W Daniel, and Joel S. Schuman. “Introduction to Gedenkschrift for David L. Epstein, MD..” Exp Eye Res 158 (May 2017): 1–2. https://doi.org/10.1016/j.exer.2017.01.008.Full Text Link to Item
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Stamer, W Daniel, and Joel S. Schuman. “Introduction to Gedenkschrift for David L. Epstein, MD.” Experimental Eye Research 158 (May 1, 2017): 1–2. https://doi.org/10.1016/j.exer2017.01.008.Full Text Link to Item
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Chandrawati, Rona, Jason Y. H. Chang, Ester Reina-Torres, Coline Jumeaux, Joseph M. Sherwood, W Daniel Stamer, Alexander N. Zelikin, Darryl R. Overby, and Molly M. Stevens. “Localized and Controlled Delivery of Nitric Oxide to the Conventional Outflow Pathway via Enzyme Biocatalysis: Toward Therapy for Glaucoma..” Adv Mater 29, no. 16 (April 2017). https://doi.org/10.1002/adma.201604932.Full Text Link to Item
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O’Callaghan, Jeffrey, Darragh E. Crosbie, Paul S. Cassidy, Joseph M. Sherwood, Cassandra Flügel-Koch, Elke Lütjen-Drecoll, Marian M. Humphries, et al. “Therapeutic potential of AAV-mediated MMP-3 secretion from corneal endothelium in treating glaucoma..” Hum Mol Genet 26, no. 7 (April 1, 2017): 1230–46. https://doi.org/10.1093/hmg/ddx028.Full Text Link to Item
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Reina-Torres, Ester, Joanne C. Wen, Katy C. Liu, Guorong Li, Joseph M. Sherwood, Jason Y. H. Chang, Pratap Challa, et al. “VEGF as a Paracrine Regulator of Conventional Outflow Facility..” Invest Ophthalmol Vis Sci 58, no. 3 (March 1, 2017): 1899–1908. https://doi.org/10.1167/iovs.16-20779.Full Text Link to Item
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Wen, Joanne C., Ester Reina-Torres, Joseph M. Sherwood, Pratap Challa, Katy C. Liu, Guorong Li, Jason Y. H. Chang, et al. “Intravitreal Anti-VEGF Injections Reduce Aqueous Outflow Facility in Patients With Neovascular Age-Related Macular Degeneration..” Invest Ophthalmol Vis Sci 58, no. 3 (March 1, 2017): 1893–98. https://doi.org/10.1167/iovs.16-20786.Full Text Link to Item
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Li, Guorong, Gang Cui, W Michael Dismuke, Iris Navarro, Kristin Perkumas, David F. Woodward, and W Daniel Stamer. “Differential response and withdrawal profile of glucocorticoid-treated human trabecular meshwork cells..” Exp Eye Res 155 (February 2017): 38–46. https://doi.org/10.1016/j.exer.2016.12.002.Full Text Link to Item
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Tam, Lawrence C. S., Ester Reina-Torres, Joseph M. Sherwood, Paul S. Cassidy, Darragh E. Crosbie, Elke Lütjen-Drecoll, Cassandra Flügel-Koch, et al. “Enhancement of Outflow Facility in the Murine Eye by Targeting Selected Tight-Junctions of Schlemm's Canal Endothelia..” Sci Rep 7 (January 16, 2017). https://doi.org/10.1038/srep40717.Full Text Link to Item
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Aboobakar, Inas F., William M. Johnson, W Daniel Stamer, Michael A. Hauser, and R Rand Allingham. “Major review: Exfoliation syndrome; advances in disease genetics, molecular biology, and epidemiology..” Exp Eye Res 154 (January 2017): 88–103. https://doi.org/10.1016/j.exer.2016.11.011.Full Text Link to Item
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Banerjee, Juni, Chi-Ting Leung, Ang Li, Kim Peterson-Yantorno, Huan Ouyang, W Daniel Stamer, and Mortimer M. Civan. “Regulatory Roles of Anoctamin-6 in Human Trabecular Meshwork Cells..” Invest Ophthalmol Vis Sci 58, no. 1 (January 1, 2017): 492–501. https://doi.org/10.1167/iovs.16-20188.Full Text Link to Item
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Chhunchha, Bhavana, Prerna Singh, W Daniel Stamer, and Dhirendra P. Singh. “Prdx6 retards senescence and restores trabecular meshwork cell health by regulating reactive oxygen species..” Cell Death Discov 3 (2017). https://doi.org/10.1038/cddiscovery.2017.60.Full Text Link to Item
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Fini, M Elizabeth, Stephen G. Schwartz, Xiaoyi Gao, Shinwu Jeong, Nitin Patel, Tatsuo Itakura, Marianne O. Price, Francis W. Price, Rohit Varma, and W Daniel Stamer. “Steroid-induced ocular hypertension/glaucoma: Focus on pharmacogenomics and implications for precision medicine..” Prog Retin Eye Res 56 (January 2017): 58–83. https://doi.org/10.1016/j.preteyeres.2016.09.003.Full Text Link to Item
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Helwa, Inas, Jingwen Cai, Michelle D. Drewry, Arthur Zimmerman, Michael B. Dinkins, Mariam Lotfy Khaled, Mutsa Seremwe, et al. “A Comparative Study of Serum Exosome Isolation Using Differential Ultracentrifugation and Three Commercial Reagents..” Plos One 12, no. 1 (2017). https://doi.org/10.1371/journal.pone.0170628.Full Text Link to Item
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Elliott, Michael H., Nicole E. Ashpole, Xiaowu Gu, Leonie Herrnberger, Mark E. McClellan, Gina L. Griffith, Alaina M. Reagan, et al. “Caveolin-1 modulates intraocular pressure: implications for caveolae mechanoprotection in glaucoma..” Sci Rep 6 (November 14, 2016). https://doi.org/10.1038/srep37127.Full Text Link to Item
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Ren, Ruiyi, Guorong Li, Thuy Duong Le, Casey Kopczynski, W Daniel Stamer, and Haiyan Gong. “Netarsudil Increases Outflow Facility in Human Eyes Through Multiple Mechanisms..” Invest Ophthalmol Vis Sci 57, no. 14 (November 1, 2016): 6197–6209. https://doi.org/10.1167/iovs.16-20189.Full Text Link to Item
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Dismuke, W Michael, Darryl R. Overby, Mortimer M. Civan, and W Daniel Stamer. “The Value of Mouse Models for Glaucoma Drug Discovery..” J Ocul Pharmacol Ther 32, no. 8 (October 2016): 486–87. https://doi.org/10.1089/jop.2016.29010.mjc.Full Text Link to Item
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Mitchell, Claire H., and W Daniel Stamer. “Dedication of Special Issue on Purinergic Regulation in the Eye to Mortimer M. Civan..” J Ocul Pharmacol Ther 32, no. 8 (October 2016). https://doi.org/10.1089/jop.2016.29018.ded.Full Text Link to Item
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Paula, Jayter S., Colm O’Brien, and W Daniel Stamer. “Life under pressure: The role of ocular cribriform cells in preventing glaucoma..” Exp Eye Res 151 (October 2016): 150–59. https://doi.org/10.1016/j.exer.2016.08.014.Full Text Link to Item
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Li, Guorong, Dibyendu Mukherjee, Iris Navarro, Nicole E. Ashpole, Joseph M. Sherwood, Jinlong Chang, Darryl R. Overby, et al. “Visualization of conventional outflow tissue responses to netarsudil in living mouse eyes..” Eur J Pharmacol 787 (September 15, 2016): 20–31. https://doi.org/10.1016/j.ejphar.2016.04.002.Full Text Link to Item
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Liu, Yutao, Jessica Cooke Bailey, Inas Helwa, W Michael Dismuke, Jingwen Cai, Michelle Drewry, Murray H. Brilliant, et al. “A Common Variant in MIR182 Is Associated With Primary Open-Angle Glaucoma in the NEIGHBORHOOD Consortium..” Invest Ophthalmol Vis Sci 57, no. 10 (August 1, 2016): 4528–35. https://doi.org/10.1167/iovs.16-19688.Full Text Link to Item
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Liu, Yutao, Jessica Cooke Bailey, Inas Helwa, W Michael Dismuke, Jingwen Cai, Michelle Drewry, Murray H. Brilliant, et al. “A Common Variant in MIR182 Is Associated With Primary Open-Angle Glaucoma in the NEIGHBORHOOD Consortium.” Investigative Ophthalmology & Visual Science 57, no. 10 (August 2016): 4528–35. https://doi.org/10.1167/iovs.16-19688.Full Text Link to Item
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Williams, Andrew M., R Rand Allingham, W Daniel Stamer, and Kelly W. Muir. “Eye Care Professionals' Perspectives on Eye Donation and an Eye Donation Registry for Research: A Single-Institution, Cross-Sectional Study..” Curr Eye Res 41, no. 6 (June 2016): 867–71. https://doi.org/10.3109/02713683.2015.1056376.Full Text Link to Item
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Williams, Andrew M., Kristin M. Perkumas, Isaac Perry, Joanne C. Wen, Janet Keeling, Michael Tramber, Paloma B. Liton, and W Daniel Stamer. “Successful Implementation of a Program for Increasing Donor Eyes for Research: The Duke-Miracles In Sight Program..” J Ocul Pharmacol Ther 32, no. 3 (April 2016): 145–49. https://doi.org/10.1089/jop.2015.0107.Full Text Link to Item
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Williams, Andrew M., W Daniel Stamer, and R Rand Allingham. “Increasing the Availability and Quality of Donor Eyes for Research..” Jama Ophthalmol 134, no. 4 (April 2016): 351–52. https://doi.org/10.1001/jamaophthalmol.2015.5492.Full Text Link to Item
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Ge, Pei, Iris D. Navarro, Marco M. Kessler, Sylvie G. Bernier, Nicholas R. Perl, Renee Sarno, Jaime Masferrer, Gerhard Hannig, and W Daniel Stamer. “The Soluble Guanylate Cyclase Stimulator IWP-953 Increases Conventional Outflow Facility in Mouse Eyes..” Invest Ophthalmol Vis Sci 57, no. 3 (March 2016): 1317–26. https://doi.org/10.1167/iovs.15-18958.Full Text Link to Item
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Dismuke, W Michael, Mikael Klingeborn, and W Daniel Stamer. “Mechanism of Fibronectin Binding to Human Trabecular Meshwork Exosomes and Its Modulation by Dexamethasone..” Plos One 11, no. 10 (2016). https://doi.org/10.1371/journal.pone.0165326.Full Text Link to Item
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Boussommier-Calleja, Alexandra, Guorong Li, Amanda Wilson, Tal Ziskind, Oana Elena Scinteie, Nicole E. Ashpole, Joseph M. Sherwood, et al. “Physical Factors Affecting Outflow Facility Measurements in Mice..” Invest Ophthalmol Vis Sci 56, no. 13 (December 2015): 8331–39. https://doi.org/10.1167/iovs.15-17106.Full Text Link to Item
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Hauser, Michael A., Inas F. Aboobakar, Yutao Liu, Shiroh Miura, Benjamin T. Whigham, Pratap Challa, Joshua Wheeler, et al. “Genetic variants and cellular stressors associated with exfoliation syndrome modulate promoter activity of a lncRNA within the LOXL1 locus..” Hum Mol Genet 24, no. 22 (November 15, 2015): 6552–63. https://doi.org/10.1093/hmg/ddv347.Full Text Link to Item
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Cai, Jingwen, Kristin M. Perkumas, Xuejun Qin, Michael A. Hauser, W Daniel Stamer, and Yutao Liu. “Expression Profiling of Human Schlemm's Canal Endothelial Cells From Eyes With and Without Glaucoma..” Invest Ophthalmol Vis Sci 56, no. 11 (October 2015): 6747–53. https://doi.org/10.1167/iovs.15-17720.Full Text Link to Item
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Dautriche, Cula N., Dennis Szymanski, Matthew Kerr, Karen Y. Torrejon, Magnus Bergkvist, Yubing Xie, John Danias, W. D. Stamer, and Susan T. Sharfstein. “A biomimetic Schlemm's canal inner wall: A model to study outflow physiology, glaucoma pathology and high-throughput drug screening..” Biomaterials 65 (October 2015): 86–92. https://doi.org/10.1016/j.biomaterials.2015.06.034.Full Text Link to Item
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Park, Chan Young, Enhua H. Zhou, Dhananjay Tambe, Bohao Chen, Tera Lavoie, Maria Dowell, Anton Simeonov, et al. “High-throughput screening for modulators of cellular contractile force..” Integr Biol (Camb) 7, no. 10 (October 2015): 1318–24. https://doi.org/10.1039/c5ib00054h.Full Text Link to Item
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Chang, Jason Y. H., W Daniel Stamer, Jacques Bertrand, A Thomas Read, Catherine M. Marando, C Ross Ethier, and Darryl R. Overby. “Role of nitric oxide in murine conventional outflow physiology..” Am J Physiol Cell Physiol 309, no. 4 (August 15, 2015): C205–14. https://doi.org/10.1152/ajpcell.00347.2014.Full Text Link to Item
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Roy Chowdhury, Uttio, Cheryl R. Hann, W Daniel Stamer, and Michael P. Fautsch. “Aqueous humor outflow: dynamics and disease..” Invest Ophthalmol Vis Sci 56, no. 5 (May 2015): 2993–3003. https://doi.org/10.1167/iovs.15-16744.Full Text Link to Item
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Dismuke, W Michael, Pratap Challa, Iris Navarro, W Daniel Stamer, and Yutao Liu. “Human aqueous humor exosomes..” Experimental Eye Research 132 (March 2015): 73–77. https://doi.org/10.1016/j.exer.2015.01.019.Full Text
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Porter, Kristine, Joshua Hirt, W Daniel Stamer, and Paloma B. Liton. “Autophagic dysregulation in glaucomatous trabecular meshwork cells..” Biochim Biophys Acta 1852, no. 3 (March 2015): 379–85. https://doi.org/10.1016/j.bbadis.2014.11.021.Full Text Link to Item
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Stamer, W Daniel, Sietse T. Braakman, Enhua H. Zhou, C Ross Ethier, Jeffrey J. Fredberg, Darryl R. Overby, and Mark Johnson. “Biomechanics of Schlemm's canal endothelium and intraocular pressure reduction..” Prog Retin Eye Res 44 (January 2015): 86–98. https://doi.org/10.1016/j.preteyeres.2014.08.002.Full Text Link to Item
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Locke, Christina J., Nicole R. Congrove, W Michael Dismuke, Trent J. Bowen, W Daniel Stamer, and Brian S. McKay. “Controlled exosome release from the retinal pigment epithelium in situ..” Exp Eye Res 129 (December 2014): 1–4. https://doi.org/10.1016/j.exer.2014.10.010.Full Text Link to Item
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Ashpole, Nicole E., Darryl R. Overby, C Ross Ethier, and W Daniel Stamer. “Shear stress-triggered nitric oxide release from Schlemm's canal cells..” Invest Ophthalmol Vis Sci 55, no. 12 (November 13, 2014): 8067–76. https://doi.org/10.1167/iovs.14-14722.Full Text Link to Item
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Lei, Yuan, William Daniel Stamer, Jihong Wu, and Xinghuai Sun. “Endothelial nitric oxide synthase-related mechanotransduction changes in aged porcine angular aqueous plexus cells..” Investigative Ophthalmology & Visual Science 55, no. 12 (November 6, 2014): 8402–8. https://doi.org/10.1167/iovs.14-14992.Full Text
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Braakman, Sietse T., Ryan M. Pedrigi, A Thomas Read, James A. E. Smith, W Daniel Stamer, C Ross Ethier, and Darryl R. Overby. “Biomechanical strain as a trigger for pore formation in Schlemm's canal endothelial cells..” Exp Eye Res 127 (October 2014): 224–35. https://doi.org/10.1016/j.exer.2014.08.003.Full Text Link to Item
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Overby, Darryl R., Enhua H. Zhou, Rocio Vargas-Pinto, Ryan M. Pedrigi, Rudolf Fuchshofer, Sietse T. Braakman, Ritika Gupta, et al. “Altered mechanobiology of Schlemm's canal endothelial cells in glaucoma..” Proc Natl Acad Sci U S A 111, no. 38 (September 23, 2014): 13876–81. https://doi.org/10.1073/pnas.1410602111.Full Text Link to Item
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Overby, Darryl R., Jacques Bertrand, Ozan-Yüksel Tektas, Alexandra Boussommier-Calleja, Martin Schicht, C Ross Ethier, David F. Woodward, W Daniel Stamer, and Elke Lütjen-Drecoll. “Ultrastructural changes associated with dexamethasone-induced ocular hypertension in mice..” Invest Ophthalmol Vis Sci 55, no. 8 (July 15, 2014): 4922–33. https://doi.org/10.1167/iovs.14-14429.Full Text Link to Item
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Overby, Darryl R., Jacques Bertrand, Martin Schicht, Friedrich Paulsen, W Daniel Stamer, and Elke Lütjen-Drecoll. “The structure of the trabecular meshwork, its connections to the ciliary muscle, and the effect of pilocarpine on outflow facility in mice..” Invest Ophthalmol Vis Sci 55, no. 6 (May 15, 2014): 3727–36. https://doi.org/10.1167/iovs.13-13699.Full Text Link to Item
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Lei, Yuan, William D. Stamer, Jihong Wu, and Xinghuai Sun. “Cell senescence reduced the mechanotransduction sensitivity of porcine angular aqueous plexus cells to elevation of pressure..” Invest Ophthalmol Vis Sci 55, no. 4 (April 11, 2014): 2324–28. https://doi.org/10.1167/iovs.13-13317.Full Text Link to Item
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Li, Guorong, Sina Farsiu, Stephanie J. Chiu, Pedro Gonzalez, Elke Lütjen-Drecoll, Darryl R. Overby, and W Daniel Stamer. “Pilocarpine-induced dilation of Schlemm's canal and prevention of lumen collapse at elevated intraocular pressures in living mice visualized by OCT..” Invest Ophthalmol Vis Sci 55, no. 6 (March 4, 2014): 3737–46. https://doi.org/10.1167/iovs.13-13700.Full Text Link to Item
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Dismuke, W Michael, Jin Liang, Darryl R. Overby, and W Daniel Stamer. “Concentration-related effects of nitric oxide and endothelin-1 on human trabecular meshwork cell contractility..” Exp Eye Res 120 (March 2014): 28–35. https://doi.org/10.1016/j.exer.2013.12.012.Full Text Link to Item
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Camras, Lucinda J., W Daniel Stamer, David Epstein, Pedro Gonzalez, and Fan Yuan. “Circumferential tensile stiffness of glaucomatous trabecular meshwork..” Invest Ophthalmol Vis Sci 55, no. 2 (February 10, 2014): 814–23. https://doi.org/10.1167/iovs.13-13091.Full Text Link to Item
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Li, Guorong, Sina Farsiu, Jianming Qiu, Angela Dixon, Chunwei Song, Stuart J. McKinnon, Fan Yuan, Pedro Gonzalez, and W Daniel Stamer. “Disease progression in iridocorneal angle tissues of BMP2-induced ocular hypertensive mice with optical coherence tomography..” Mol Vis 20 (2014): 1695–1709.Link to Item
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Rogers, Morgan E., Iris D. Navarro, Kristin M. Perkumas, Shannon M. Niere, R Rand Allingham, Craig E. Crosson, and W Daniel Stamer. “Pigment epithelium-derived factor decreases outflow facility..” Invest Ophthalmol Vis Sci 54, no. 10 (October 11, 2013): 6655–61. https://doi.org/10.1167/iovs.13-12766.Full Text Link to Item
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Liu, Yutao, R Rand Allingham, Xuejun Qin, David Layfield, Andrew E. Dellinger, Jason Gibson, Joshua Wheeler, Allison E. Ashley-Koch, W Daniel Stamer, and Michael A. Hauser. “Gene expression profile in human trabecular meshwork from patients with primary open-angle glaucoma..” Invest Ophthalmol Vis Sci 54, no. 9 (September 27, 2013): 6382–89. https://doi.org/10.1167/iovs.13-12128.Full Text Link to Item
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Lei, Yuan, William D. Stamer, Jihong Wu, and Xinghuai Sun. “Oxidative stress impact on barrier function of porcine angular aqueous plexus cell monolayers..” Invest Ophthalmol Vis Sci 54, no. 7 (July 18, 2013): 4827–35. https://doi.org/10.1167/iovs.12-11435.Full Text Link to Item
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Wang, Jenny W., David F. Woodward, and W Daniel Stamer. “Differential effects of prostaglandin E2-sensitive receptors on contractility of human ocular cells that regulate conventional outflow..” Invest Ophthalmol Vis Sci 54, no. 7 (July 16, 2013): 4782–90. https://doi.org/10.1167/iovs.13-12363.Full Text Link to Item
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Li, G., P. Gonzalez, L. J. Camras, I. Navarro, J. Qiu, P. Challa, and W. D. Stamer. “Optimizing gene transfer to conventional outflow cells in living mouse eyes..” Exp Eye Res 109 (April 2013): 8–16. https://doi.org/10.1016/j.exer.2013.01.005.Full Text Link to Item
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Stamer, W Daniel, Emely A. Hoffman, Edit Kurali, and Achim H. Krauss. “Unique response profile of trabecular meshwork cells to the novel selective glucocorticoid receptor agonist, GW870086X..” Invest Ophthalmol Vis Sci 54, no. 3 (March 1, 2013): 2100–2107. https://doi.org/10.1167/iovs.12-11298.Full Text Link to Item
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Arnold, John J., Mark S. Hansen, Gregory S. Gorman, Toshihiro Inoue, Vasantha Rao, Simone Spellen, Ronald N. Hunsinger, et al. “The effect of Rho-associated kinase inhibition on the ocular penetration of timolol maleate..” Invest Ophthalmol Vis Sci 54, no. 2 (February 7, 2013): 1118–26. https://doi.org/10.1167/iovs.12-10583.Full Text Link to Item
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Giovingo, Michael, Michael Nolan, Ryan McCarty, Iok-Hou Pang, Abbot F. Clark, Rachel M. Beverley, Steven Schwartz, et al. “sCD44 overexpression increases intraocular pressure and aqueous outflow resistance..” Mol Vis 19 (2013): 2151–64.Link to Item
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McKay, Brian S., Nicole R. Congrove, Adiv A. Johnson, W Michael Dismuke, Trent J. Bowen, and W Daniel Stamer. “A role for myocilin in receptor-mediated endocytosis..” Plos One 8, no. 12 (2013). https://doi.org/10.1371/journal.pone.0082301.Full Text Link to Item
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Boussommier-Calleja, Alexandra, Jacques Bertrand, David F. Woodward, C Ross Ethier, W Daniel Stamer, and Darryl R. Overby. “Pharmacologic manipulation of conventional outflow facility in ex vivo mouse eyes..” Invest Ophthalmol Vis Sci 53, no. 9 (August 24, 2012): 5838–45. https://doi.org/10.1167/iovs.12-9923.Full Text Link to Item
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Camras, Lucinda J., W Daniel Stamer, David Epstein, Pedro Gonzalez, and Fan Yuan. “Differential effects of trabecular meshwork stiffness on outflow facility in normal human and porcine eyes..” Invest Ophthalmol Vis Sci 53, no. 9 (August 9, 2012): 5242–50. https://doi.org/10.1167/iovs.12-9825.Full Text Link to Item
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Zhou, E. H., R. Krishnan, W. D. Stamer, K. M. Perkumas, K. Rajendran, J. F. Nabhan, Q. Lu, J. J. Fredberg, and M. Johnson. “Mechanical responsiveness of the endothelial cell of Schlemm's canal: scope, variability and its potential role in controlling aqueous humour outflow..” J R Soc Interface 9, no. 71 (June 7, 2012): 1144–55. https://doi.org/10.1098/rsif.2011.0733.Full Text Link to Item
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Stamer, W Daniel. “The cell and molecular biology of glaucoma: mechanisms in the conventional outflow pathway..” Invest Ophthalmol Vis Sci 53, no. 5 (May 4, 2012): 2470–72. https://doi.org/10.1167/iovs.12-9483f.Full Text Link to Item
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Dismuke, W Michael, Brian S. McKay, and W Daniel Stamer. “Myocilin, a component of a membrane-associated protein complex driven by a homologous Q-SNARE domain..” Biochemistry 51, no. 17 (May 1, 2012): 3606–13. https://doi.org/10.1021/bi300073r.Full Text Link to Item
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Baetz, Nicholas W., W Daniel Stamer, and Andrea J. Yool. “Stimulation of aquaporin-mediated fluid transport by cyclic GMP in human retinal pigment epithelium in vitro..” Invest Ophthalmol Vis Sci 53, no. 4 (April 24, 2012): 2127–32. https://doi.org/10.1167/iovs.11-8471.Full Text Link to Item
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Li, Ang, Juni Banerjee, Kim Peterson-Yantorno, W Daniel Stamer, Chi Ting Leung, and Mortimer M. Civan. “Effects of cardiotonic steroids on trabecular meshwork cells: search for mediator of ouabain-enhanced outflow facility..” Exp Eye Res 96, no. 1 (March 2012): 4–12. https://doi.org/10.1016/j.exer.2012.01.009.Full Text Link to Item
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Perkumas, K. M., and W. D. Stamer. “Protein markers and differentiation in culture for Schlemm's canal endothelial cells..” Exp Eye Res 96, no. 1 (March 2012): 82–87. https://doi.org/10.1016/j.exer.2011.12.017.Full Text Link to Item
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Stamer, W Daniel, and Ted S. Acott. “Current understanding of conventional outflow dysfunction in glaucoma..” Curr Opin Ophthalmol 23, no. 2 (March 2012): 135–43. https://doi.org/10.1097/ICU.0b013e32834ff23e.Full Text Link to Item
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Li, Ang, Chi Ting Leung, Kim Peterson-Yantorno, W Daniel Stamer, Claire H. Mitchell, and Mortimer M. Civan. “Mechanisms of ATP release by human trabecular meshwork cells, the enabling step in purinergic regulation of aqueous humor outflow..” J Cell Physiol 227, no. 1 (January 2012): 172–82. https://doi.org/10.1002/jcp.22715.Full Text Link to Item
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Stamer, W Daniel, Yuan Lei, Alexandra Boussommier-Calleja, Darryl R. Overby, and C Ross Ethier. “eNOS, a pressure-dependent regulator of intraocular pressure..” Invest Ophthalmol Vis Sci 52, no. 13 (December 9, 2011): 9438–44. https://doi.org/10.1167/iovs.11-7839.Full Text Link to Item
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Li, Ang, Chi Ting Leung, Kim Peterson-Yantorno, W Daniel Stamer, and Mortimer M. Civan. “Cytoskeletal dependence of adenosine triphosphate release by human trabecular meshwork cells..” Invest Ophthalmol Vis Sci 52, no. 11 (October 10, 2011): 7996–8005. https://doi.org/10.1167/iovs.11-8170.Full Text Link to Item
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Millard, Lindsay H., David F. Woodward, and W Daniel Stamer. “The role of the prostaglandin EP4 receptor in the regulation of human outflow facility..” Invest Ophthalmol Vis Sci 52, no. 6 (June 1, 2011): 3506–13. https://doi.org/10.1167/iovs.10-6510.Full Text Link to Item
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Stamer, W. D., E. A. Hoffman, J. M. Luther, D. L. Hachey, and K. L. Schey. “Protein profile of exosomes from trabecular meshwork cells..” J Proteomics 74, no. 6 (May 16, 2011): 796–804. https://doi.org/10.1016/j.jprot.2011.02.024.Full Text Link to Item
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Sumida, Grant M., and W Daniel Stamer. “S1Pâ‚‚ receptor regulation of sphingosine-1-phosphate effects on conventional outflow physiology..” Am J Physiol Cell Physiol 300, no. 5 (May 2011): C1164–71. https://doi.org/10.1152/ajpcell.00437.2010.Full Text Link to Item
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Lei, Yuan, Darryl R. Overby, Alexandra Boussommier-Calleja, W Daniel Stamer, and C Ross Ethier. “Outflow physiology of the mouse eye: pressure dependence and washout..” Invest Ophthalmol Vis Sci 52, no. 3 (March 2011): 1865–71. https://doi.org/10.1167/iovs.10-6019.Full Text Link to Item
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VanderWyst, Saumya S., Kristin M. Perkumas, A Thomas Read, Darryl R. Overby, and W Daniel Stamer. “Structural basement membrane components and corresponding integrins in Schlemm's canal endothelia..” Mol Vis 17 (January 19, 2011): 199–209.Link to Item
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Li, Ang, Juni Banerjee, Chi Ting Leung, Kim Peterson-Yantorno, W Daniel Stamer, and Mortimer M. Civan. “Mechanisms of ATP release, the enabling step in purinergic dynamics..” Cell Physiol Biochem 28, no. 6 (2011): 1135–44. https://doi.org/10.1159/000335865.Full Text Link to Item
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Pedrigi, Ryan M., David Simon, Ashley Reed, W Daniel Stamer, and Darryl R. Overby. “A model of giant vacuole dynamics in human Schlemm's canal endothelial cells..” Exp Eye Res 92, no. 1 (January 2011): 57–66. https://doi.org/10.1016/j.exer.2010.11.003.Full Text Link to Item
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Howell, Kyle G., Anne M. Vrabel, Uttio Roy Chowdhury, William Daniel Stamer, and Michael P. Fautsch. “Myocilin levels in primary open-angle glaucoma and pseudoexfoliation glaucoma human aqueous humor..” J Glaucoma 19, no. 9 (December 2010): 569–75. https://doi.org/10.1097/IJG.0b013e3181d13020.Full Text Link to Item
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Sumida, Grant M., and W Daniel Stamer. “Sphingosine-1-phosphate enhancement of cortical actomyosin organization in cultured human Schlemm's canal endothelial cell monolayers..” Invest Ophthalmol Vis Sci 51, no. 12 (December 2010): 6633–38. https://doi.org/10.1167/iovs.10-5391.Full Text Link to Item
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Lei, Yuan, Darryl R. Overby, A Thomas Read, W Daniel Stamer, and C Ross Ethier. “A new method for selection of angular aqueous plexus cells from porcine eyes: a model for Schlemm's canal endothelium..” Invest Ophthalmol Vis Sci 51, no. 11 (November 2010): 5744–50. https://doi.org/10.1167/iovs.10-5703.Full Text Link to Item
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Stamer, W Daniel, David Piwnica, Thierry Jolas, Robert W. Carling, Clive L. Cornell, Hans Fliri, Jose Martos, Simon N. Pettit, Jenny W. Wang, and David F. Woodward. “Cellular basis for bimatoprost effects on human conventional outflow..” Invest Ophthalmol Vis Sci 51, no. 10 (October 2010): 5176–81. https://doi.org/10.1167/iovs.09-4955.Full Text Link to Item
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Hutchinson, Anthony J., Serena C. Coons, Chih-Ling Chou, Wei Xu, W Daniel Stamer, David F. Woodward, and John W. Regan. “Induction of angiogenic immediate early genes by activation of FP prostanoid receptors in cultured human ciliary smooth muscle cells..” Curr Eye Res 35, no. 5 (May 2010): 408–18. https://doi.org/10.3109/02713680903581021.Full Text Link to Item
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Mortazavi, Ariane M., Bruce R. Simon, W Daniel Stamer, and Jonathan P. Vande Geest. “Drained secant modulus for human and porcine peripapillary sclera using unconfined compression testing..” Exp Eye Res 89, no. 6 (December 2009): 892–97. https://doi.org/10.1016/j.exer.2009.07.011.Full Text Link to Item
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Stamer, W Daniel, A Thomas Read, Grant M. Sumida, and C Ross Ethier. “Sphingosine-1-phosphate effects on the inner wall of Schlemm's canal and outflow facility in perfused human eyes..” Exp Eye Res 89, no. 6 (December 2009): 980–88. https://doi.org/10.1016/j.exer.2009.08.008.Full Text Link to Item
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Nehmé, Alissar, Edward K. Lobenhofer, W Daniel Stamer, and Jeffrey L. Edelman. “Glucocorticoids with different chemical structures but similar glucocorticoid receptor potency regulate subsets of common and unique genes in human trabecular meshwork cells..” Bmc Med Genomics 2 (September 10, 2009). https://doi.org/10.1186/1755-8794-2-58.Full Text Link to Item
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Bruhn, R. L., W. D. Stamer, L. A. Herrygers, J. M. Levine, and R. J. Noecker. “Relationship between glaucoma and selenium levels in plasma and aqueous humour..” Br J Ophthalmol 93, no. 9 (September 2009): 1155–58. https://doi.org/10.1136/bjo.2007.125997.Full Text Link to Item
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Fatma, Nigar, Eri Kubo, Carol B. Toris, W. D. Stamer, Carl B. Camras, and Dhirendra P. Singh. “PRDX6 attenuates oxidative stress- and TGFbeta-induced abnormalities of human trabecular meshwork cells..” Free Radic Res 43, no. 9 (September 2009): 783–95. https://doi.org/10.1080/10715760903062887.Full Text Link to Item
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Ramos, Renata F., Grant M. Sumida, and W Daniel Stamer. “Cyclic mechanical stress and trabecular meshwork cell contractility..” Invest Ophthalmol Vis Sci 50, no. 8 (August 2009): 3826–32. https://doi.org/10.1167/iovs.08-2694.Full Text Link to Item
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Baetz, N. W., E. A. Hoffman, A. J. Yool, and W. D. Stamer. “Role of aquaporin-1 in trabecular meshwork cell homeostasis during mechanical strain..” Exp Eye Res 89, no. 1 (June 15, 2009): 95–100. https://doi.org/10.1016/j.exer.2009.02.018.Full Text Link to Item
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Overby, Darryl R., W Daniel Stamer, and Mark Johnson. “The changing paradigm of outflow resistance generation: towards synergistic models of the JCT and inner wall endothelium..” Exp Eye Res 88, no. 4 (April 2009): 656–70. https://doi.org/10.1016/j.exer.2008.11.033.Full Text Link to Item
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Hoffman, Emely A., Kristin M. Perkumas, Lindsey M. Highstrom, and W Daniel Stamer. “Regulation of myocilin-associated exosome release from human trabecular meshwork cells..” Invest Ophthalmol Vis Sci 50, no. 3 (March 2009): 1313–18. https://doi.org/10.1167/iovs.08-2326.Full Text Link to Item
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Zhang, Youwen, Bryan R. Davidson, W Daniel Stamer, Jennifer K. Barton, Lihua Y. Marmorstein, and Alan D. Marmorstein. “Enhanced inflow and outflow rates despite lower IOP in bestrophin-2-deficient mice..” Invest Ophthalmol Vis Sci 50, no. 2 (February 2009): 765–70. https://doi.org/10.1167/iovs.08-2501.Full Text Link to Item
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Stamer, W Daniel, Darren W. H. Chan, Shannon M. Conley, Serena Coons, and C Ross Ethier. “Aquaporin-1 expression and conventional aqueous outflow in human eyes..” Exp Eye Res 87, no. 4 (October 2008): 349–55. https://doi.org/10.1016/j.exer.2008.06.018.Full Text Link to Item
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Lopez, Vanessa M., Christina L. Decatur, W Daniel Stamer, Ronald M. Lynch, and Brian S. McKay. “L-DOPA is an endogenous ligand for OA1..” Plos Biol 6, no. 9 (September 30, 2008). https://doi.org/10.1371/journal.pbio.0060236.Full Text Link to Item
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Ramos, Renata F., and W Daniel Stamer. “Effects of cyclic intraocular pressure on conventional outflow facility..” Invest Ophthalmol Vis Sci 49, no. 1 (January 2008): 275–81. https://doi.org/10.1167/iovs.07-0863.Full Text Link to Item
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Wan, Zhou, David F. Woodward, and W Daniel Stamer. “Endogenous Bioactive Lipids and the Regulation of Conventional Outflow Facility..” Expert Rev Ophthalmol 3, no. 4 (2008): 457–70. https://doi.org/10.1586/17469899.3.4.457.Full Text Link to Item
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Wan, Zhou, David F. Woodward, Clive L. Cornell, Hans G. Fliri, José L. Martos, Simon N. Pettit, Jenny W. Wang, et al. “Bimatoprost, prostamide activity, and conventional drainage..” Invest Ophthalmol Vis Sci 48, no. 9 (September 2007): 4107–15. https://doi.org/10.1167/iovs.07-0080.Full Text Link to Item
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Ramos, Renata F., James B. Hoying, Marlys H. Witte, and W. Daniel Stamer. “Schlemm's canal endothelia, lymphatic, or blood vasculature?.” J Glaucoma 16, no. 4 (June 2007): 391–405. https://doi.org/10.1097/IJG.0b013e3180654ac6.Full Text Link to Item
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Daniel Stamer, W., D. W. -. H. Chan, and C. Ross Ethier. “Targeted gene transfer to Schlemm's canal by retroperfusion..” Exp Eye Res 84, no. 5 (May 2007): 843–49. https://doi.org/10.1016/j.exer.2007.01.001.Full Text Link to Item
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Perkumas, K. M., E. A. Hoffman, B. S. McKay, R. R. Allingham, and W. D. Stamer. “Myocilin-associated exosomes in human ocular samples..” Exp Eye Res 84, no. 1 (January 2007): 209–12. https://doi.org/10.1016/j.exer.2006.09.020.Full Text Link to Item
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Stamer, W. D., K. M. Perkumas, E. A. Hoffman, B. C. Roberts, D. L. Epstein, and B. S. McKay. “Coiled-coil targeting of myocilin to intracellular membranes..” Exp Eye Res 83, no. 6 (December 2006): 1386–95. https://doi.org/10.1016/j.exer.2006.07.018.Full Text Link to Item
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Boassa, Daniela, W Daniel Stamer, and Andrea J. Yool. “Ion channel function of aquaporin-1 natively expressed in choroid plexus..” J Neurosci 26, no. 30 (July 26, 2006): 7811–19. https://doi.org/10.1523/JNEUROSCI.0525-06.2006.Full Text Link to Item
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Wan, Z., L. Brigatti, J. Ranger-Moore, C. R. Ethier, and W. D. Stamer. “Rate of change in central corneal thickness: a viability indicator for conventional drainage tissues in organ culture..” Exp Eye Res 82, no. 6 (June 2006): 1086–93. https://doi.org/10.1016/j.exer.2005.10.027.Full Text Link to Item
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Conley, Shannon M., Brian S. McKay, A Jay Gandolfi, and W Daniel Stamer. “Alterations in human trabecular meshwork cell homeostasis by selenium..” Exp Eye Res 82, no. 4 (April 2006): 637–47. https://doi.org/10.1016/j.exer.2005.08.024.Full Text Link to Item
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Hoffman, Emely A., Shannon M. Conley, W Daniel Stamer, and Brian S. McKay. “Barriers to productive transfection of trabecular meshwork cells..” Mol Vis 11 (October 26, 2005): 869–75.Link to Item
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Hardy, Katharine M., Emely A. Hoffman, Pedro Gonzalez, Brian S. McKay, and W Daniel Stamer. “Extracellular trafficking of myocilin in human trabecular meshwork cells..” J Biol Chem 280, no. 32 (August 12, 2005): 28917–26. https://doi.org/10.1074/jbc.M504803200.Full Text Link to Item
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Karl, Mike O., Johannes C. Fleischhauer, W Daniel Stamer, Kim Peterson-Yantorno, Claire H. Mitchell, R. A. Stone, and M. M. Civan. “Differential P1-purinergic modulation of human Schlemm's canal inner-wall cells..” Am J Physiol Cell Physiol 288, no. 4 (April 2005): C784–94. https://doi.org/10.1152/ajpcell.00333.2004.Full Text Link to Item
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Liton, Paloma B., Xialin Liu, W Daniel Stamer, Pratap Challa, David L. Epstein, and Pedro Gonzalez. “Specific targeting of gene expression to a subset of human trabecular meshwork cells using the chitinase 3-like 1 promoter..” Invest Ophthalmol Vis Sci 46, no. 1 (January 2005): 183–90. https://doi.org/10.1167/iovs.04-0330.Full Text Link to Item
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Burke, A. G., W. Zhou, E. T. O’Brien, B. C. Roberts, and W. D. Stamer. “Effect of hydrostatic pressure gradients and Na2EDTA on permeability of human Schlemm's canal cell monolayers..” Curr Eye Res 28, no. 6 (June 2004): 391–98. https://doi.org/10.1080/02713680490503697.Full Text Link to Item
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Ethier, C Ross, Shigeo Wada, Darren Chan, and W Daniel Stamer. “Experimental and numerical studies of adenovirus delivery to outflow tissues of perfused human anterior segments..” Invest Ophthalmol Vis Sci 45, no. 6 (June 2004): 1863–70. https://doi.org/10.1167/iovs.03-1133.Full Text Link to Item
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Gonzalez, Pedro, Montserrat Caballero, Paloma B. Liton, W Daniel Stamer, and David L. Epstein. “Expression analysis of the matrix GLA protein and VE-cadherin gene promoters in the outflow pathway..” Invest Ophthalmol Vis Sci 45, no. 5 (May 2004): 1389–95. https://doi.org/10.1167/iovs.03-0537.Full Text Link to Item
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Conley, Shannon M., Roberta L. Bruhn, Parham V. Morgan, and W Daniel Stamer. “Selenium's effects on MMP-2 and TIMP-1 secretion by human trabecular meshwork cells..” Invest Ophthalmol Vis Sci 45, no. 2 (February 2004): 473–79. https://doi.org/10.1167/iovs.03-0767.Full Text Link to Item
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Stamer, W Daniel, Dean Bok, Jane Hu, Glenn J. Jaffe, and Brian S. McKay. “Aquaporin-1 channels in human retinal pigment epithelium: role in transepithelial water movement..” Invest Ophthalmol Vis Sci 44, no. 6 (June 2003): 2803–8. https://doi.org/10.1167/iovs.03-0001.Full Text Link to Item
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Fleischhauer, J. C., C. H. Mitchell, W. D. Stamer, M. O. Karl, K. Peterson-Yantorno, and M. M. Civan. “Common actions of adenosine receptor agonists in modulating human trabecular meshwork cell transport..” J Membr Biol 193, no. 2 (May 15, 2003): 121–36. https://doi.org/10.1007/s00232-002-2013-5.Full Text Link to Item
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Porter, Amy C., Samuel P. S. Svensson, W Daniel Stamer, Joseph J. Bahl, Jeremy G. Richman, and John W. Regan. “Alpha-2 adrenergic receptors stimulate actin organization in developing fetal rat cardiac myocytes..” Life Sci 72, no. 13 (February 14, 2003): 1455–66. https://doi.org/10.1016/s0024-3205(02)02381-0.Full Text Link to Item
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Heimark, Ronald L., Salma Kaochar, and W Daniel Stamer. “Human Schlemm's canal cells express the endothelial adherens proteins, VE-cadherin and PECAM-1..” Curr Eye Res 25, no. 5 (November 2002): 299–308. https://doi.org/10.1076/ceyr.25.5.299.13495.Full Text Link to Item
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Mitchell, Claire H., Johannes C. Fleischhauer, W Daniel Stamer, K. Peterson-Yantorno, and Mortimer M. Civan. “Human trabecular meshwork cell volume regulation..” Am J Physiol Cell Physiol 283, no. 1 (July 2002): C315–26. https://doi.org/10.1152/ajpcell.00544.2001.Full Text Link to Item
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Huang, Yi, W Daniel Stamer, Todd L. Anthony, David V. Kumar, Paul A. St John, and John W. Regan. “Expression of alpha(2)-adrenergic receptor subtypes in prenatal rat spinal cord..” Brain Res Dev Brain Res 133, no. 2 (February 28, 2002): 93–104. https://doi.org/10.1016/s0165-3806(02)00275-4.Full Text Link to Item
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Yool, Andrea J., Olga H. Brokl, Thomas L. Pannabecker, William H. Dantzler, and W Daniel Stamer. “Tetraethylammonium block of water flux in Aquaporin-1 channels expressed in kidney thin limbs of Henle's loop and a kidney-derived cell line..” Bmc Physiol 2 (2002).Link to Item
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Stamer, W. D., S. F. Golightly, Y. Hosohata, E. P. Ryan, A. C. Porter, E. Varga, R. J. Noecker, C. C. Felder, and H. I. Yamamura. “Cannabinoid CB(1) receptor expression, activation and detection of endogenous ligand in trabecular meshwork and ciliary process tissues..” Eur J Pharmacol 431, no. 3 (November 23, 2001): 277–86. https://doi.org/10.1016/s0014-2999(01)01438-8.Full Text Link to Item
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Stamer, W. D., K. Peppel, M. E. O’Donnell, B. C. Roberts, F. Wu, and D. L. Epstein. “Expression of aquaporin-1 in human trabecular meshwork cells: role in resting cell volume..” Invest Ophthalmol Vis Sci 42, no. 8 (July 2001): 1803–11.Link to Item
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Sun, X. C., K. T. Allen, Q. Xie, W. D. Stamer, and J. A. Bonanno. “Effect of AQP1 expression level on Co(2) permeability in bovine corneal endothelium..” Invest Ophthalmol Vis Sci 42, no. 2 (February 2001): 417–23.Link to Item
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Stamer, D. W., B. C. Roberts, D. L. Epstein, and R. R. Allingham. “Isolation of primary open-angle glaucomatous trabecular meshwork cells from whole eye tissue..” Curr Eye Res 20, no. 5 (May 2000): 347–50.Link to Item
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Stamer, W. D., B. C. Roberts, and D. L. Epstein. “Hydraulic pressure stimulates adenosine 3',5'-cyclic monophosphate accumulation in endothelial cells from Schlemm's canal..” Invest Ophthalmol Vis Sci 40, no. 9 (August 1999): 1983–88.Link to Item
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Stamer, W. D., B. C. Roberts, D. N. Howell, and D. L. Epstein. “Isolation, culture, and characterization of endothelial cells from Schlemm's canal..” Invest Ophthalmol Vis Sci 39, no. 10 (September 1998): 1804–12.Link to Item
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Anthony, T. L., K. L. Pierce, W. D. Stamer, and J. W. Regan. “Prostaglandin F2 alpha receptors in the human trabecular meshwork..” Invest Ophthalmol Vis Sci 39, no. 2 (February 1998): 315–21.Link to Item
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Stamer, W. D., R. W. Snyder, and J. W. Regan. “Characterization of the transmembrane orientation of aquaporin-1 using antibodies to recombinant fusion proteins..” Biochemistry 35, no. 50 (December 17, 1996): 16313–18. https://doi.org/10.1021/bi9619536.Full Text Link to Item
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Stamer, W. D., Y. Huang, R. E. Seftor, S. S. Svensson, R. W. Snyder, and J. W. Regan. “Cultured human trabecular meshwork cells express functional alpha 2A adrenergic receptors..” Invest Ophthalmol Vis Sci 37, no. 12 (November 1996): 2426–33.Link to Item
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Yool, A. J., W. D. Stamer, and J. W. Regan. “Forskolin stimulation of water and cation permeability in aquaporin 1 water channels..” Science 273, no. 5279 (August 30, 1996): 1216–18. https://doi.org/10.1126/science.273.5279.1216.Full Text Link to Item
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Huang, Y., D. W. Gil, P. Vanscheeuwijck, W. D. Stamer, and J. W. Regan. “Localization of alpha 2-adrenergic receptor subtypes in the anterior segment of the human eye with selective antibodies..” Invest Ophthalmol Vis Sci 36, no. 13 (December 1995): 2729–39.Link to Item
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Stamer, W. D., R. E. Seftor, R. W. Snyder, and J. W. Regan. “Cultured human trabecular meshwork cells express aquaporin-1 water channels..” Curr Eye Res 14, no. 12 (December 1995): 1095–1100. https://doi.org/10.3109/02713689508995815.Full Text Link to Item
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Stamer, W. D., R. E. Seftor, S. K. Williams, H. A. Samaha, and R. W. Snyder. “Isolation and culture of human trabecular meshwork cells by extracellular matrix digestion..” Curr Eye Res 14, no. 7 (July 1995): 611–17. https://doi.org/10.3109/02713689508998409.Full Text Link to Item
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Stamer, W. D., R. W. Snyder, B. L. Smith, P. Agre, and J. W. Regan. “Localization of aquaporin CHIP in the human eye: implications in the pathogenesis of glaucoma and other disorders of ocular fluid balance..” Invest Ophthalmol Vis Sci 35, no. 11 (October 1994): 3867–72.Link to Item
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Seftor, R. E., W. D. Stamer, E. A. Seftor, and R. W. Snyder. “Dexamethasone decreases tissue plasminogen activator activity in trabecular meshwork organ and cell cultures..” J Glaucoma 3, no. 4 (1994): 323–28.Link to Item
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Book Sections
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Stamer, W. D., N. W. Baetz, and A. J. Yool. “Chapter 2 Ocular Aquaporins and Aqueous Humor Dynamics,” 62:47–70, 2008. https://doi.org/10.1016/S1063-5823(08)00402-X.Full Text
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Yool, A. J., and W. D. Stamer. “Novel roles for aquaporins as gated ion channels,” 32:351–79, 2004. https://doi.org/10.1016/S1569-2558(03)32015-6.Full Text
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Other Articles
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Stamer, W Daniel. “Implications of sustained elevation in extracellular ATP in retina following chronic ocular hypertension..” Invest Ophthalmol Vis Sci, May 2015. https://doi.org/10.1167/iovs.15-17032.Full Text Link to Item
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Novack, Gary D., and W Daniel Stamer. “The "T" in JOPT..” J Ocul Pharmacol Ther, April 2015. https://doi.org/10.1089/jop.2015.1504.Full Text Link to Item
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Samples, John R., and W Daniel Stamer. “The trabecular meshwork special double issue, inspired by the TM study club..” J Ocul Pharmacol Ther, March 2014. https://doi.org/10.1089/jop.2014.1504.Full Text Link to Item
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Stamer, W Daniel. “David L. Epstein, MD, MMM (1944-2014)..” J Ocul Pharmacol Ther, March 2014. https://doi.org/10.1089/jop.2014.1506.Full Text Link to Item
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Stamer, W Daniel. “Thirty years of JOPT..” J Ocul Pharmacol Ther, February 2014. https://doi.org/10.1089/jop.2014.1502.Full Text Link to Item
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Stamer, W. D. “New developments for JOPT.” Journal of Ocular Pharmacology and Therapeutics, October 1, 2012. https://doi.org/10.1089/jop.2012.1502.Full Text
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Stamer, W Daniel. “Moving forward in ocular pharmacology..” J Ocul Pharmacol Ther, April 2012. https://doi.org/10.1089/jop.2012.1501.Full Text Link to Item
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Fautsch, Michael P., and Douglas H. Johnson. “Aqueous humor outflow: what do we know? Where will it lead us?.” Invest Ophthalmol Vis Sci, October 2006. https://doi.org/10.1167/iovs.06-0830.Full Text Link to Item
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Agre, P., M. D. Lee, S. Devidas, and W. B. Guggino. “Aquaporins and ion conductance..” Science, March 7, 1997.Link to Item
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Conference Papers
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Cai, Jingwen, William M. Johnson, Kristin Marie Perkumas, W Daniel Stamer, and Yutao Liu. “TGF beta Signaling in Human Schlemm's Canal Endothelial Cells.” In Investigative Ophthalmology & Visual Science, Vol. 59. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2018.Link to Item
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Elliott, Michael H., Mark E. McClellan, Willard M. Freeman, and W Daniel Stamer. “ROLE OF CAVEOLAE AS MECHANOSENSORS IN SCHLEMM'S CANAL.” In Investigative Ophthalmology & Visual Science, Vol. 59. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2018.Link to Item
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Ethier, C Ross, Ke Wang, Guorong Li, A Thomas Read, Iris Navarro, Ashim K. Mitra, W Daniel Stamer, and Todd Sulchek. “Trabecular meshwork stiffness and outflow resistance are related.” In Investigative Ophthalmology & Visual Science, Vol. 59. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2018.Link to Item
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Fuchshofer, Rudolf, Andrea E. Dillinger, Michaela Anna Guter, Franziska Scherl, Kristin Marie Perkumas, W Daniel Stamer, and Miriam Breunig. “Targeting of CD44 by hyaluronan coated-nanoparticles in outflow tissues - a new therapeutic approach for glaucoma.” In Investigative Ophthalmology & Visual Science, Vol. 59. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2018.Link to Item
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Itakura, Tatsuo, Andrew Webster, Jose M. Gonzalez, James C. H. Tan, Maria Sibug-Saber, Cheryl Mae Craft, Janice A. Vranka, et al. “Homeostatic Role for GPR158 in Modulating Intraocular Pressure (IOP).” In Investigative Ophthalmology & Visual Science, Vol. 59. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2018.Link to Item
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Li, Guorong, Vibhuti Agrahari, Iris Navarro, Sina Farsiu, Ashim K. Mitra, and W Daniel Stamer. “Pentablock Copolymer Dexamethasone Nanoformulations Induced Ocular Hypertension in Mice.” In Investigative Ophthalmology & Visual Science, Vol. 59. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2018.Link to Item
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Liu, Yutao, Mariam Lotfy Khaled, Yelena Bykhovskaya, Hanzhou Li, W Daniel Stamer, Hongyan Xu, R Rand Allingham, Michael A. Hauser, and Yaron Rabinowitz. “Long Non-Coding RNAs in Keratoconus-affected Human Cornea.” In Investigative Ophthalmology & Visual Science, Vol. 59. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2018.Link to Item
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McDonnell, Fiona, W Michael Dismuke, Darryl R. Overby, and W Daniel Stamer. “DISTAL OUTFLOW RESISTANCE CAN BE REGULATED PHARMACOLOGICALLY.” In Investigative Ophthalmology & Visual Science, Vol. 59. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2018.Link to Item
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Navarro, Iris, Marco Kessler, Una L. Kelly, Megan Parker, Gerhard Hannig, Pei Ge, and W Daniel Stamer. “sGC Stimulators and Trabecular Meshwork Biology.” In Investigative Ophthalmology & Visual Science, Vol. 59. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2018.Link to Item
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Overby, Darryl R., Michael Madekurozwa, W Daniel Stamer, and Joseph Sherwood. “Modulation of outflow facility by the ocular pulse.” In Investigative Ophthalmology & Visual Science, Vol. 59. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2018.Link to Item
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O’Callaghan, Jeffrey, Paul S. Cassidy, Ester Reina-Torres, Joseph Sherwood, Marian M. Humphries, Matthew Campbell, Colm J. O’Brien, et al. “INDUCIBLE MMP-3 EXPRESSION IN A STEROID-INDUCED MURINE MODEL OF GLAUCOMA.” In Investigative Ophthalmology & Visual Science, Vol. 59. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2018.Link to Item
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Torrejon, Karen Yud, Ellen L. Papke, Andrea Unser, Matthew Kerr, W Daniel Stamer, and Feryan Ahmed. “Nitric Oxide Induces Changes in the Cytoskeleton and ECM of TGF beta 2-treated Trabecular Meshwork and Schlemm's canal cells.” In Investigative Ophthalmology & Visual Science, Vol. 59. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2018.Link to Item
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Aboobakar, Inas F., David Corcoran, William Marshall Johnson, R Rand Allingham, W Daniel Stamer, and Michael A. Hauser. “Knockdown of the lncRNA LOXL1-AS1 and the protein-coding gene LOXL1 alters expression of genes and pathways implicated in exfoliation syndrome pathogenesis.” In Investigative Ophthalmology & Visual Science, Vol. 58. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2017.Link to Item
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Albers, David, Guorong Li, William K. McVicar, and W Daniel Stamer. “Intraocular pressure lowering following topical (ocular) delivery of trabodenoson: Effects of preservative and age in living mice..” In Investigative Ophthalmology & Visual Science, Vol. 58. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2017.Link to Item
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Drewry, Michelle, John Kuchtey, Iris Navarro, Shruti Sharma, W Daniel Stamer, Ashok Sharma, Pratap Challa, Rachel W. Kuchtey, and Yutao Liu. “Differentially expressed microRNAs in the aqueous humor of patients with exfoliation glaucoma or primary open-angle glaucoma.” In Investigative Ophthalmology & Visual Science, Vol. 58. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2017.Link to Item
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Fuchshofer, Rudolf, Duong Nguyen, W Daniel Stamer, and Mark Johnson. “Nitric oxide changes the biomechanical behavior of Schlemm canal cells and HUVECs.” In Investigative Ophthalmology & Visual Science, Vol. 58. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2017.Link to Item
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Helwa, Inas, Michelle Drewry, William M. Johnson, W Michael Dismuke, Inas F. Aboobakar, Kristin Marie Perkumas, R Rand Allingham, Michael A. Hauser, W Daniel Stamer, and Yutao Liu. “Differential miRNA Expression in Response to Mechanical Stress in Human Trabecular Meshwork Cells.” In Investigative Ophthalmology & Visual Science, Vol. 58. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2017.Link to Item
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Johnson, William Marshall, Inas F. Aboobakar, Laura Finnegan, R Rand Allingham, Michael A. Hauser, and W Daniel Stamer. “Identification of the hnRNPL and LOXL1-AS1 lncRNA complex: Implications for pathology in exfoliation glaucoma.” In Investigative Ophthalmology & Visual Science, Vol. 58. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2017.Link to Item
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Li, Guorong, Vibhuti Agrahari, Vivek Agrahari, Abhirup Mandal, Ashim K. Mitra, and W Daniel Stamer. “Delivery of Dexamethasone from Novel Pentablock Copolymer-Based Nanoformulation Promotes Prolonged Secretion of myocilin from Human Trabecular Meshwork Cells.” In Investigative Ophthalmology & Visual Science, Vol. 58. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2017.Link to Item
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Li, Hoi Lam, Ashim Dey, Shasha Yu, Sze Wan Shan, W Daniel Stamer, Henry Ho-lung Chan, Chi-ho To, Kin Chiu, and Chi-wai Do. “Effects of intravitreal administration of baicalein on intraocular pressure and retinal thickness in Sprague-Dawley rats.” In Investigative Ophthalmology & Visual Science, Vol. 58. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2017.Link to Item
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Overby, Darryl R., Sietse Braakman, Alice Spenlehauer, Justino R. Rodrigues, Carter Teal, A Thomas Read, W Daniel Stamer, and C Ross Ethier. “Stretch-Dependent Pore Formation in Glaucomatous Schlemm's Canal Cells.” In Investigative Ophthalmology & Visual Science, Vol. 58. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2017.Link to Item
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Perkumas, Kristin Marie, Nicole E. Ashpole, Joan Kalnitsky, and W Daniel Stamer. “Performance of shear stress-responsive reporter viruses in human Schlemm's canal monolayers.” In Investigative Ophthalmology & Visual Science, Vol. 58. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2017.Link to Item
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Singh, Dhirendra P., Bhavana Chhunchha, Prerna Singh, W Daniel Stamer, and Eri Kubo. “Stabilization Of Prdx6 Activity By Targeted Mutation Of Sumoylation Sites Protects Trabecular Meshwork Cells From Oxidative Damage.” In Investigative Ophthalmology & Visual Science, Vol. 58. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2017.Link to Item
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Vahabikashi, Amir, Kristin Marie Perkumas, Chan Young Park, W Daniel Stamer, Jeffrey Fredberg, and Mark Johnson. “The role of alpha-actinin and RhoA in the mechanical properties of Schlemm's canal cells.” In Investigative Ophthalmology & Visual Science, Vol. 58. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2017.Link to Item
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Wang, Ke, A Thomas Read, Guorong Li, W Daniel Stamer, and C Ross Ethier. “Effects of dexamethasone on trabecular meshwork stiffness in mice.” In Investigative Ophthalmology & Visual Science, Vol. 58. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2017.Link to Item
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Wu, Kevin, Ruiyi Ren, Guorong Li, Casey Kopczynski, W Daniel Stamer, and Haiyan Gong. “Netarsudil increases size of giant vacuoles in Schlemm's canal of perfused human eyes.” In Investigative Ophthalmology & Visual Science, Vol. 58. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2017.Link to Item
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Ashpole, Nicole E., Dibyendu Mukherjee, Guorong Li, Paolo Maccarini, Joseph M. Sherwood, C Ross Ethier, Darryl R. Overby, Sina Farsiu, and W Daniel Stamer. “IOP-induced Changes in Schlemm's Canal Dimensions and the Relation to Shear Stress.” In Investigative Ophthalmology & Visual Science, Vol. 57. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2016.Link to Item
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Crosbie, Darragh, James Keaney, Joseph M. Sherwood, Darryl R. Overby, W Daniel Stamer, Lawrence Tam, and Peter Humphries. “Assessment of age-related eye morphology and aqueous humor flow dynamics in the DBA/2J mouse model of pigmentary glaucoma using ocular MRI and anterior chamber iPerfusion systems.” In Investigative Ophthalmology & Visual Science, Vol. 57. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2016.Link to Item
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Dismuke, W Michael, and W Daniel Stamer. “A role for exosomes in steroid induced ECM accumulation in the TM.” In Investigative Ophthalmology & Visual Science, Vol. 57. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2016.Link to Item
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Fuchshofer, Rudolf, Gunter Meister, Markus Kretz, W Daniel Stamer, and Mark Johnson. “Role of microRNAs in glaucomatous outflow resistance dysregulation.” In Investigative Ophthalmology & Visual Science, Vol. 57. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2016.Link to Item
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Ge, Pei, Iris Navarro, Marco Kessler, Sylvie Bernier, Nicholas Perl, Renee Sarno, Jaime Masferrer, Gerhard Hannig, and W Daniel Stamer. “The Soluble Guanylate Cyclase Stimulator IWP-953 Increases Conventional Outflow Facility in Mouse Eyes.” In Investigative Ophthalmology & Visual Science, Vol. 57. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2016.Link to Item
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Li, Guorong, Dibyendu Mukherjee, Iris Navarro, Sina Farsiu, Pedro Gonzalez, Casey Kopczynski, and W Daniel Stamer. “Real-time Visualization of AR-13324 Effects on Schlemm's Canal and Scleral Vessels in Living Mice.” In Investigative Ophthalmology & Visual Science, Vol. 57. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2016.Link to Item
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Mukherjee, Dibyendu, Guorong Li, W Daniel Stamer, and Sina Farsiu. “Segmentation and analysis software for mapping aqueous humor outflow pattern in living mice.” In Investigative Ophthalmology & Visual Science, Vol. 57. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2016.Link to Item
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Paula, Jayter Silva, Kristin Perkumas, Nicole E. Ashpole, and W Daniel Stamer. “Functional renin receptors in human Schlemm's Canal cells.” In Investigative Ophthalmology & Visual Science, Vol. 57. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2016.Link to Item
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Ren, Ruiyi, Guorong Li, Duong Le Thuy, Casey Kopczynski, W Daniel Stamer, and Haiyan Gong. “The mechanisms of increasing outflow facility by AR-13324M in human eyes.” In Investigative Ophthalmology & Visual Science, Vol. 57. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2016.Link to Item
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Shan, Sze Wan, Rachel Ka-man Chun, Thomas C. Lam, King Kit Li, W Daniel Stamer, Chi-wai Do, and Chi-ho To. “Quantitative proteomics analysis of human trabecular meshwork (hTM) in response to corticosteroids using SWATH (TM)-MS.” In Investigative Ophthalmology & Visual Science, Vol. 57. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2016.Link to Item
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Banerjee, Juni, Chi-Ting Leung, Ang Li, Kim Peterson-Yantorno, Huan Ouyang, W Daniel Stamer, and Mortimer M. Civan. “Role of anoctamin in glaucoma and cancer.” In International Journal of Molecular Medicine, 38:S42–S42. SPANDIDOS PUBL LTD, 2016.Link to Item
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Aboobakar, Inas F., Jin Liang, Michael A. Hauser, R Rand Allingham, and W Daniel Stamer. “Cyclic mechanical stress alters LOXL1 gene expression in trabecular meshwork and Schlemm's canal cells.” In Investigative Ophthalmology & Visual Science, Vol. 56. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2015.Link to Item
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Chang, Jason Y. H., Sietse T. Braakman, Zahra Mohri, Peter Weinberg, C Ross Ethier, W Daniel Stamer, and Darryl R. Overby. “Colocalization of segmental outflow and endogenous eNOS activity in the conventional outflow pathway of mice.” In Investigative Ophthalmology & Visual Science, Vol. 56. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2015.Link to Item
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Dismuke, W Michael, and W Daniel Stamer. “Trabecular Meshwork Exosomes: Fibronectin Binding and ECM homeostasis.” In Investigative Ophthalmology & Visual Science, Vol. 56. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2015.Link to Item
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Elliott, Michael H., Stefanie M. Hauck, Mikhail G. Dozmorov, Jin Liang, Mark E. Mcclellan, Jonathan D. Wren, and W Daniel Stamer. “Caveolae and conventional outflow: Proteomic profiling of outflow tissue caveolae and evidence of mechanosensing.” In Investigative Ophthalmology & Visual Science, Vol. 56. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2015.Link to Item
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Li, Guorong, W Michael Dismuke, Iris Navarro, Kristin M. Perkumas, David F. Woodward, and W Daniel Stamer. “Secretion profile of human trabecular meshwork cells following recovery from prolonged corticosteroid treatment.” In Investigative Ophthalmology & Visual Science, Vol. 56. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2015.Link to Item
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Li, Hoi Lam, Nicole E. Ashpole, Iris D. Navarro, Thomas C. Lam, Ho Lung Henry Chan, Chi Ho To, W Daniel Stamer, and Chi-wai Do. “Baicalein lowers intraocular pressure and increases outflow facility in mouse eye.” In Investigative Ophthalmology & Visual Science, Vol. 56. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2015.Link to Item
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Overby, Darryl R., Ester Reina-Torres, Joanne C. Wen, Katy Liu, Guorong Li, Joseph M. Sherwood, R Rand Allingham, and W Daniel Stamer. “The Effects of VEGF and anti-VEGF on Outflow Facility in Mice and Humans.” In Investigative Ophthalmology & Visual Science, Vol. 56. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2015.Link to Item
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Singh, Dhirendra P., Nigar Fatma, Bhavana Chhunchha, W Daniel Stamer, and Eri Kubo. “Replicative Senescence of Trabecular Meshwork Cells Is Associated With Loss Of Prdx6 By Sumoylation.” In Investigative Ophthalmology & Visual Science, Vol. 56. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2015.Link to Item
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Torrejon, Karen Yud, Cula Dautriche, Ellen Papke, W Daniel Stamer, John Danias, Magnus Bergkvist, Susan T. Sharfstein, and Yubing Xie. “Recreation of a 3-D Physiological Model of Conventional Outflow Tract in vitro.” In Investigative Ophthalmology & Visual Science, Vol. 56. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2015.Link to Item
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Bowen, Trent J., Nicole R. Congrove, W Daniel Stamer, and Brian S. McKay. “Myocilin Mutations Alter GPCR Endocytosis.” In Investigative Ophthalmology & Visual Science, Vol. 55. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2014.Link to Item
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Braakman, Sietse T., W Daniel Stamer, and Darryl R. Overby. “A fluorescent permeability assay for Schlemm's canal endothelial cells in response to stretch.” In Investigative Ophthalmology & Visual Science, Vol. 55. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2014.Link to Item
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Chang, Jason Y. H., C Ross Ethier, W Daniel Stamer, and Darryl R. Overby. “Differential effects of nitric oxide synthase inhibitors on conventional outflow facility in mice.” In Investigative Ophthalmology & Visual Science, Vol. 55. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2014.Link to Item
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Dismuke, W Michael, and W Daniel Stamer. “Trabecular meshwork exosomes enhance cellular collagen uptake.” In Investigative Ophthalmology & Visual Science, Vol. 55. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2014.Link to Item
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Elliott, Michael H., Xiaowu Gu, Nicole E. Ashpole, Gina L. Griffith, Timothy M. Boyce, Masaki Tanito, Ernst R. Tamm, and W Daniel Stamer. “Role of Caveolin-1 in Intraocular Pressure and Conventional Outflow Regulation.” In Investigative Ophthalmology & Visual Science, Vol. 55. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2014.Link to Item
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Li, Guorong, Pedro Gonzalez, Sina Farsiu, and W Daniel Stamer. “Dynamic alterations in conventional outflow function in Bmp2-induced ocular hypertensive mice.” In Investigative Ophthalmology & Visual Science, Vol. 55. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2014.Link to Item
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Liang, Jin, Iris D. Navarro, Pedro Gonzalez, Fan Yuan, and W Daniel Stamer. “Mechanical and cytokine stimulation of smooth muscle actin expression in human trabecular meshwork cells.” In Investigative Ophthalmology & Visual Science, Vol. 55. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2014.Link to Item
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Liu, Katy C., Guorong Li, Darryl R. Overby, and W Daniel Stamer. “Role of VEGF in Conventional Outflow Homeostasis.” In Investigative Ophthalmology & Visual Science, Vol. 55. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2014.Link to Item
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Locke, Christina, Nicole R. Congrove, W Daniel Stamer, and Brian S. McKay. “Myocilin is constitutively released with exosomes from RPE in situ.” In Investigative Ophthalmology & Visual Science, Vol. 55. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2014.Link to Item
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Overby, Darryl R., Amir Vahabikashi, Rocio Vargas-Pinto, Sietse T. Braakman, Ryan Pedrigi, Ritika Gupta, Kristin Marie Perkumas, W Daniel Stamer, C Ross Ethier, and Mark Johnson. “The Effect of Cell Stiffness on I- and B-Pore Formation in Schlemm's Canal Endothelial Cells.” In Investigative Ophthalmology & Visual Science, Vol. 55. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2014.Link to Item
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Reina-Torres, Ester, Joseph M. Sherwood, W Daniel Stamer, and Darryl R. Overby. “Role of Vascular Endothelial Growth Factor (VEGF) in the regulation of conventional outflow facility in mice.” In Investigative Ophthalmology & Visual Science, Vol. 55. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2014.Link to Item
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Zhou, Enhua H., Rudolf Fuchshofer, W Daniel Stamer, Quynh N. Dang, Jae H. Kim, Kristin Marie Perkumas, Mark Johnson, and Jeffrey J. Fredberg. “Mechanosensitivity of Schlemm's canal endothelial cells from normal and glaucomatous eyes.” In Investigative Ophthalmology & Visual Science, Vol. 55. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2014.Link to Item
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Ashpole, Nicole, Darryl Overby, C. Ethier, and W Daniel Stamer. “Shear Stress Stimulation of NO release from Schlemm's Canal Cells.” In Investigative Ophthalmology & Visual Science, Vol. 54. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2013.Link to Item
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Banerjee, Juni, Ang Li, Chi Ting Leung, Kim Peterson-Yantorno, W Daniel Stamer, and Mortimer Civan. “Regulatory Roles of Anoctamin-6 in Human Trabecular Meshwork Cells.” In Investigative Ophthalmology & Visual Science, Vol. 54. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2013.Link to Item
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Braakman, Sietse, Kristin Perkumas, Darryl Overby, David Woodward, and W Daniel Stamer. “Sphingosine-1-Phosphate signaling in cultured human trabecular meshwork cells.” In Investigative Ophthalmology & Visual Science, Vol. 54. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2013.Link to Item
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Calleja, Alexandra Boussommier, W Daniel Stamer, C. Ethier, and Darryl Overby. “Metabolic Dependence of Conventional Outflow Facility in Mice.” In Investigative Ophthalmology & Visual Science, Vol. 54. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2013.Link to Item
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Camras, Lucinda, W Daniel Stamer, David Epstein, Pedro Gonzalez, and Fan Yuan. “Circumferential Trabecular Meshwork Stiffness in Glaucomatous Eyes.” In Investigative Ophthalmology & Visual Science, Vol. 54. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2013.Link to Item
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Chang, Jason, Catherine Marando, C. Ethier, W Daniel Stamer, and Darryl Overby. “Effects of Nitric Oxide Donor on Outflow Facility in Mice.” In Investigative Ophthalmology & Visual Science, Vol. 54. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2013.Link to Item
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Dismuke, W., Brian McKay, Aaditya Khatri, Kristin Perkumas, and W Daniel Stamer. “Tracking protein endocytosis and trafficking to exosomes released from trabecular meshwork cells.” In Investigative Ophthalmology & Visual Science, Vol. 54. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2013.Link to Item
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Fatma, Nigar, Eri Kubo, Bhavana Chhunchha, W Daniel Stamer, and Dhirendra Singh. “Prdx6 abates the process of senescence and restores trabecular meshwork cell integrity by regulating Telomerase, p16 and p21 Expression.” In Investigative Ophthalmology & Visual Science, Vol. 54. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2013.Link to Item
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Johnson, Mark, Ryan Pedrigi, Rocio Vargas-Pinto, Ritika Gupta, Sietse Braakman, C. Ethier, Kristin Perkumas, W Daniel Stamer, and Darryl Overby. “Elevated stiffness of cultured glaucomatous Schlemm's canal (SC) cells correlates with impaired pore formation.” In Investigative Ophthalmology & Visual Science, Vol. 54. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2013.Link to Item
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Lei, Yuan, W Daniel Stamer, Jihong Wu, and Xinghuai Sun. “Oxidative Stress Impacts On Barrier Function of Porcine Angular Aqueous Plexus Cell Monolayers.” In Investigative Ophthalmology & Visual Science, Vol. 54. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2013.Link to Item
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Mckay, Brian, Nicole Congrove, William Dismuke, and W Daniel Stamer. “A Role for Myocilin in Receptor Endocytosis.” In Investigative Ophthalmology & Visual Science, Vol. 54. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2013.Link to Item
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Overby, Darryl, Jacques Bertrand, Ozan Tektas, Alexandra Boussommier Calleja, W Daniel Stamer, C. Ethier, David Woodward, and Elke Luetjen-Drecoll. “Functional and Morphological Alterations Associated with Steroid-Induced Ocular Hypertension in Mice.” In Investigative Ophthalmology & Visual Science, Vol. 54. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2013.Link to Item
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Porter, Kristine, Ping Xu, W Daniel Stamer, and Paloma Liton. “DIMINISHED AUTOPHAGIC CAPACITY OF GLAUCOMATOUS TRABECULAR MESHWORK CELLS.” In Investigative Ophthalmology & Visual Science, Vol. 54. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2013.Link to Item
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Rogers, Morgan, Iris Navarro, Kristin Perkumas, R Rand Allingham, Pratap Challa, Craig Crosson, and W Daniel Stamer. “PEDF Effects on Outflow Facility.” In Investigative Ophthalmology & Visual Science, Vol. 54. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2013.Link to Item
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Zhou, Enhua, W Daniel Stamer, Chan Young Park, Kristin Perkumas, James Butler, Mark Johnson, and Jeffrey Fredberg. “Monolayer traction forces of Schlemm's canal endothelial cells.” In Investigative Ophthalmology & Visual Science, Vol. 54. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2013.Link to Item
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Pedrigi, R. M., R. Gupta, S. T. Braakman, W. D. Stamer, C. R. Ethier, and D. R. Overby. “Pore formation in Schlemm's canal endothelial cells is mechano-sensitive and impaired in glaucoma.” In Asme 2012 Summer Bioengineering Conference, Sbc 2012, 1183–84, 2012. https://doi.org/10.1115/SBC2012-80713.Full Text
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Stamer, W. D., R. W. Snyder, T. H. Burkey, and J. W. Regan. “Activation of α2A-adrenergic receptors in human trabecular meshwork cells stimulates MAP kinase activity.” In Investigative Ophthalmology and Visual Science, Vol. 37, 1996.
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