Selected Grants
Quantitative assessment of glaucomatous conventional outflow dynamics
ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2019 - 2029Caveolae-based Mechanosensors for Conventional Outflow Regulation
ResearchPrincipal Investigator · Awarded by The University of Oklahoma Health Sciences Center · 2024 - 2028eNOS-Dependent Mechanoregulation of Intraocular Pressure
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2012 - 2026Effect of adipose-derived mesenchymal stem cells in TGFb1 adenovirus OHT model
ResearchPrincipal Investigator · Awarded by Wills Eye · 2024 - 2026Role of Tissue Resident Macrophages in the Conventional Outflow Function
ResearchMentor · Awarded by National Institutes of Health · 2021 - 2025OCT measurement of trabecular meshwork function in vivo
ResearchPrincipal Investigator · Awarded by Georgia Institute of Technology · 2020 - 2025Molecular Mechanisms of Exfoliation Glaucoma
ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2019 - 2025Autophagy regulates endothelial nitric oxide (NO) synthase/NO in Schlemm¿s canal cells in response to shear stress
ResearchCollaborator · Awarded by BrightFocus Foundation · 2022 - 2025Testing additivity of two outflow targets
ResearchPrincipal Investigator · Awarded by Ollin Biosciences, Inc. · 2024 - 2025Selective targeting of Schlemm's Canal inner wall for next-generation glaucoma drugs
ResearchPrincipal Investigator · Awarded by BrightFocus Foundation · 2021 - 2025Determining durable changes in outflow function of Durysta
ResearchPrincipal Investigator · Awarded by AbbVie Inc. · 2023 - 2025Novel Extended Release Glaucoma Therapy for Once Daily Dosing
ResearchPrincipal Investigator · Awarded by University of Tennessee Health Science Center · 2023 - 2024Elucidating novel mechanisms for glucocorticoid-induced ocular hypertension.
ResearchPrincipal Investigator · Awarded by Massachusetts Eye and Ear Infirmary · 2023 - 2023ANGPTL7 effects on outflow
ResearchPrincipal Investigator · Awarded by Broadwing Bio · 2022 - 2023Genetics of glucocorticoid-induced intraocular pressure rise
ResearchPrincipal Investigator · Awarded by Massachusetts Eye and Ear Infirmary · 2021 - 2023Development of an Anesthesia Free Tonometer Tip
ResearchCo Investigator · Awarded by North Carolina Biotechnology Center · 2022 - 2023Testing effect of sustained release vs cyclic exposure of bimatoprost on MMP/TIMP/ECM expression by outflow cells
ResearchPrincipal Investigator · Awarded by Allergan, Inc. · 2018 - 2022The Role of RPE-derived Exosomes in Deposit Formation and ECM Modulation
ResearchCo Investigator · Awarded by National Institutes of Health · 2021 - 2022"Concepts and Breakthroughs in Glaucoma" Conference
ConferencePrincipal Investigator · Awarded by National Institutes of Health · 2021 - 2022Exosomes and conventional outflow homeostasis
ResearchMentor · Awarded by National Institutes of Health · 2020 - 2022Abnormal Extracellular Matrix Homeostasis of Trabecular Meshwork Cells in Pseudoexfoliation Syndrome and Glaucoma
ResearchCo Investigator · Awarded by The Glaucoma Foundation · 2020 - 2022The Role of Macrophages in Conventional Outflow Homeostasis
ResearchMentor · Awarded by American Glaucoma Society · 2020 - 2021Generating TM Cells for evaluating the impact of knocking out, inserting, or repairing various gene targets
ResearchPrincipal Investigator · Awarded by Editas Medicine Inc. · 2019 - 2021Elucidating novel mechanisms for glucocorticoid-induced ocular hypertension.
ResearchPrincipal Investigator · Awarded by Massachusetts Eye and Ear Infirmary · 2020 - 2020Caveolin-mediated mechanosensation in Schlemm¿s canal endothelia
FellowshipPrincipal Investigator · Awarded by Research To Prevent Blindness, Inc. · 2019 - 2020The Mechanical Basis of Primary Open Angle Glaucoma
ResearchPrincipal Investigator · Awarded by Northwestern University · 2011 - 2020Netarsudil effects on outflow tissue behavior in model of steroid-induced glaucoma
ResearchPrincipal Investigator · Awarded by Aerie Pharmaceuticals, Inc. · 2017 - 2019Efficacy testing of BZ371C on outflow facility in mouse eyes
ResearchPrincipal Investigator · Awarded by Biozeus · 2019 - 2019Aerpio RSA
ResearchPrincipal Investigator · Awarded by Aerpio Therapeutics · 2018 - 2019Basic Science Catalyzing Treatments for Glaucoma
ConferencePrincipal Investigator · Awarded by National Institutes of Health · 2017 - 2018Role of non-coding RNAs in glaucomatous outflow resistance dysregulation
ResearchPrincipal Investigator · Awarded by Universitat Regensburg · 2016 - 2018The Role of Exosomes in Dry AMD
ResearchCollaborator · Awarded by BrightFocus Foundation · 2015 - 2018MicroRNA-directed modulation of intraocular pressure
ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2013 - 2018OCT measurement of TM/SC stiffness in living mice
ResearchCollaborator · Awarded by BrightFocus Foundation · 2015 - 2017sGC stimulators and trabecular meshwork biology
ResearchPrincipal Investigator · Awarded by Ironwood Pharmaceuticals, Inc. · 2016 - 2017Duke-MiS Eye Tissue Bank and Donor Registry Project Duke Eye Tissue Bank/Registry
ResearchPrincipal Investigator · Awarded by Miracles in Sight · 2016 - 2017Trabodenoson and conventional outflow function
ResearchPrincipal Investigator · Awarded by inotek pharmaceuticals corporation · 2015 - 2017Role of Exosomes in Glaucomatous Lamina Cribrosa Remodeling
ResearchCollaborator · Awarded by Glaucoma Research Foundation · 2016 - 2017Mechanisms in Exfoliation Glaucoma: Effect of Genetic Risk Variants and Ocular Cell Stressors on LOXL1 Expression
ResearchPrincipal Investigator · Awarded by The Glaucoma Foundation · 2015 - 2016Shear stress regulation of barrier function in Schlemm's canal
FellowshipPrincipal Investigator · Awarded by National Institutes of Health · 2014 - 2016Lysosomal enzymes, Glycosaminoglycans and Outflow Pathway Physiology
ResearchCollaborator · Awarded by Glaucoma Research Foundation · 2015 - 2016Ocular Pharmacology and Therapeutics Conference
ConferencePrincipal Investigator · Awarded by National Institutes of Health · 2014 - 2015sGC stimulator effects on outflow facility
ResearchPrincipal Investigator · Awarded by Ironwood Pharmaceuticals, Inc. · 2014 - 2015Effects of rho kinase inhibitors on outflow facility and PEFL in human donor eyes
ResearchPrincipal Investigator · Awarded by Aerie Pharmaceuticals, Inc. · 2015 - 2015Effects of rho kinase inhibitors on outflow facility and PEFL in human donor eyes
ResearchPrincipal Investigator · Awarded by Aerie Pharmaceuticals, Inc. · 2014 - 2015Exosomal RNAs and Aqueous Humor Dynamics in Exfoliation Glaucoma
ResearchCo Investigator · Awarded by Glaucoma Research Foundation · 2014 - 2014Testing anti-S1P/LPA biologicals in living mice
ResearchPrincipal Investigator · Awarded by Lpath Incorporated · 2013 - 2014Aquaporin 1 And Aqueous Humor Outflow In The Eye
ResearchPI-Fellow · Awarded by National Institutes of Health · 1998 - 1999Aquaporin And Aqueous Humor Outflow In The Human Eye
ResearchPI-Fellow · Awarded by National Institutes of Health · 1997 - 1999External Relationships
- AbbVie, Inc.
- Broadwing Bio
- Editas Medicine, Inc.
- Exhaura
- Glauconix
- Qlaris bio
- Starlight Bio
- The Hong Kong Polytechnic University
This faculty member (or a member of their immediate family) has reported outside activities with the companies, institutions, or organizations listed above. This information is available to institutional leadership and, when appropriate, management plans are in place to address potential conflicts of interest.