Scholars@Duke

• Background
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  Education, Training, & Certifications

  • M.B.B.S., University of West Indies (West Indies) 1968
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  Duke Appointment History

  • Chief of the Division of Pain Management, Anesthesiology, Pain Management, Anesthesiology 2005 - 2012
  • Professor of Anesthesiology, Anesthesiology, Pain Management, Anesthesiology 2005 - 2012
  • Instructor, Temporary in the Department of Anesthesiology, Anesthesiology, Pain Management, Anesthesiology 2005
• Publications & Artistic Works
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  Selected Publications

  • Academic Articles

    • Kennedy, John S., Harry E. Gwirtsman, Dennis E. Schmidt, Benjamin W. Johnson, Elliot Fielstein, Ronald M. Salomon, Richard G. Shiavi, Michael H. Ebert, Winston C. V. Parris, and Peter T. Loosen. “Serial cerebrospinal fluid tryptophan and 5-hydroxy indoleacetic acid concentrations in healthy human subjects.” Life Sciences 71, no. 14 (August 2002): 1703–15. https://doi.org/10.1016/s0024-3205(02)01899-4.
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    • Parris, W. C. V. “Chronic pain - The state of the art.” Nowotwory 49, no. SUPPL. 3 (January 1, 2000): 7–9.
    • Kennedy, J. S., R. J. Polinsky, B. Johnson, P. Loosen, A. Enz, R. Laplanche, D. Schmidt, L. C. Mancione, W. C. Parris, and M. H. Ebert. “Preferential cerebrospinal fluid acetylcholinesterase inhibition by rivastigmine in humans.” J Clin Psychopharmacol 19, no. 6 (December 1999): 513–21. https://doi.org/10.1097/00004714-199912000-00005.
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    • Kaplan, R., W. C. Parris, M. L. Citron, D. Zhukovsky, R. F. Reder, B. J. Buckley, and R. F. Kaiko. “Comparison of controlled-release and immediate-release oxycodone tablets in patients with cancer pain.” J Clin Oncol 16, no. 10 (October 1998): 3230–37. https://doi.org/10.1200/JCO.1998.16.10.3230.
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    • Parris, W. C., B. W. Johnson, M. K. Croghan, M. R. Moore, A. Khojasteh, R. F. Reder, R. F. Kaiko, and B. J. Buckley. “The use of controlled-release oxycodone for the treatment of chronic cancer pain: a randomized, double-blind study.” J Pain Symptom Manage 16, no. 4 (October 1998): 205–11. https://doi.org/10.1016/s0885-3924(98)00064-5.
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    • Citron, M. L., R. Kaplan, W. C. Parris, M. K. Croghan, L. H. Herbst, R. J. Rosenbluth, R. F. Reder, N. S. Slagle, B. J. Buckley, and R. F. Kaiko. “Long-term administration of controlled-release oxycodone tablets for the treatment of cancer pain.” Cancer Invest 16, no. 8 (1998): 562–71. https://doi.org/10.3109/07357909809032886.
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    • Parris, W. C. V. “President's message.” Pain Clinic 11, no. 1 (January 1, 1998): 3–4.
    • Livengood, J. M., W. C. Parris, M. B. Rudder, M. S. Farrar, and C. G. Strassle. “TennCare patients in chronic pain: is Medicaid reform really different?” Tenn Med 90, no. 5 (May 1997): 183–84.
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    • Parris, W. C. “Post-dural puncture headache and epidural blood patch in an AIDS patient.” Journal of Clinical Anesthesia 9, no. 1 (February 1997): 87–88. https://doi.org/10.1016/s0952-8180(96)00204-8.
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    • Parris, W. C., P. K. Janicki, B. Johnson, and J. L. Horn. “Intrathecal ketorolac tromethamine produces analgesia after chronic constriction injury of sciatic nerve in rat.” Can J Anaesth 43, no. 8 (August 1996): 867–70. https://doi.org/10.1007/BF03013041.
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    • Parris, W. C., P. K. Janicki, B. Johnson, J. Livengood, and L. Mathews. “Persistent pain associated with long-term intrathecal morphine administration.” South Med J 89, no. 4 (April 1996): 417–19. https://doi.org/10.1097/00007611-199604000-00014.
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    • Parris, W. C. V. “Common chronic pain syndromes.” Pain Digest 6, no. 2 (March 1, 1996): 83–93.
    • Parris, W. C. V., R. B. Benson, and J. M. Livengood. “The importance of a multidisciplinary approach to pain management.” Pain Digest 6, no. 2 (March 1, 1996): 94–96.
    • Livengood, J. M., and W. C. V. Parris. “Post-traumatic stress disorder in chronic pain patients.” Pain Digest 6, no. 5 (January 1, 1996): 290–94.
    • Parris, W. C. V. “Perspectives of chronic pain management: Present and future.” Pain Digest 6, no. 2 (January 1, 1996): 67–70.
    • Livengood, J. M., and W. C. V. Parris. “Use of biofeedback with chronic pain patients: Are there ever contraindications?” Pain Digest 5, no. 2 (January 1, 1995): 90–92.
    • Livengood, J. M., C. M. Young, and W. C. V. Parris. “Implications of multiple personality disorder for treatment of chronic pain.” Pain Digest 4, no. 3 (January 1, 1994): 191–94.
    • Parris, W. C. V., P. K. Janicki, B. Johnson, L. Mathews, and J. L. Horn. “Ketorolac tromethamine produces analgesia after intrathecal administration in rat model of chronic neuropathic pain.” Regional Anesthesia 19, no. 2 SUPPL. (1994).
    • Parris, W. C., P. K. Janicki, B. W. Johnson, and L. Mathews. “Infrared laser diode irradiation has no behavioral or biochemical effect on pain in the sciatic nerve ligation-induced mononeuropathy in rat.” Anesth Prog 41, no. 4 (1994): 95–99.
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    • Nagaro, T., and T. Arai. “Anterior spinal artery syndrome?” Anesthesiology 79, no. 5 (November 1993): 1156–57.
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    • Parris, W. C., B. V. Sastry, J. R. Kambam, R. J. Naukam, and B. W. Johnson. “Immunoreactive substance P in human saliva. A possible marker of chronic pain.” Ann N Y Acad Sci 694 (September 20, 1993): 308–10. https://doi.org/10.1111/j.1749-6632.1993.tb18373.x.
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    • Parris, W. C., and H. S. Kirshner. “Motor paralysis of the lower extremities following lumbar sympathetic block.” Anesthesiology 78, no. 5 (May 1993): 981–83. https://doi.org/10.1097/00000542-199305000-00024.
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    • Gibbons, J. J. “Somatosensory evoked potentials and stellate ganglion block.” Clin J Pain 8, no. 2 (June 1992): 181–82. https://doi.org/10.1097/00002508-199206000-00024.
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    • Livengood, J. M., and W. C. Parris. “Early detection measures and triage procedures for suicide ideation in chronic pain patients.” Clin J Pain 8, no. 2 (June 1992): 164–69. https://doi.org/10.1097/00002508-199206000-00016.
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    • Parris, W. C. “Chronic headache resulting from postoperative supraorbital neuralgia.” Anesth Analg 74, no. 6 (June 1992): 934–35. https://doi.org/10.1213/00000539-199206000-00033.
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    • Parris, W. C., and E. M. Lee. “Anaesthesia for laparoscopic cholecystectomy.” Anaesthesia 46, no. 11 (November 1991): 997. https://doi.org/10.1111/j.1365-2044.1991.tb09896.x.
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    • Hyman, S. A., W. C. Parris, N. H. Prysi, C. Skelley, and K. Lindsey. “Somatosensory evoked potentials are unchanged by reflex sympathetic dystrophy and by stellate ganglion block.” Clin J Pain 7, no. 3 (September 1991): 226–29. https://doi.org/10.1097/00002508-199109000-00009.
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    • Naukam, R. J., W. C. Parris, J. R. Kambam, and J. B. Kruskal. “The effects of neurokinin A, neurokinin B, and eledoisin on substance P analysis.” J Clin Monit 7, no. 2 (April 1991): 181–85. https://doi.org/10.1007/bf01618120.
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    • Parris, W. C., B. C. Reddy, H. W. White, and D. M. McGrath. “Stellate ganglion blocks in pediatric patients.” Anesth Analg 72, no. 4 (April 1991): 552–56. https://doi.org/10.1213/00000539-199104000-00024.
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    • Jamison, R. N., B. A. Stetson, and W. C. Parris. “The relationship between cigarette smoking and chronic low back pain.” Addict Behav 16, no. 3–4 (1991): 103–10. https://doi.org/10.1016/0306-4603(91)90002-y.
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    • Kambam, J. R., J. J. Franks, W. Parris, R. J. Naukam, and W. Wright. “Prophylactic administration of nicardipine protects from cocaine induced cardio-respiratory toxicity in rats.” Regional Anesthesia 16, no. 1 SUPPL. (1991).
    • Kambam, J. R., W. C. Parris, R. J. Naukam, J. J. Franks, and B. V. Sastry. “In vitro effects of fluoride and bromide on pseudocholinesterase and acetylcholinesterase activities.” Can J Anaesth 37, no. 8 (November 1990): 916–19. https://doi.org/10.1007/BF03006636.
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    • Jamison, R. N., B. Stetson, T. Sbrocco, and W. C. Parris. “Effects of significant weight gain on chronic pain patients.” Clin J Pain 6, no. 1 (March 1990): 47–50. https://doi.org/10.1097/00002508-199003000-00009.
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    • Parris, W. C. “Suprascapular nerve block: a safer technique.” Anesthesiology 72, no. 3 (March 1990): 580–81. https://doi.org/10.1097/00000542-199003000-00041.
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    • Kambam, J. R., W. Merrill, W. Parris, R. Alhaddad, R. Naukam, J. Stewart, H. Bender, and B. V. R. Sastry. “Substance P, acetylcholinesterase, and β-endorphin levels in the plasma and pericardial fluid of patients with and without angina pectoris.” Journal of Laboratory and Clinical Medicine 116, no. 5 (1990): 707–10.
    • Parris, W. C., J. R. Kambam, R. J. Naukam, and B. V. Rama Sastry. “Immunoreactive substance P is decreased in saliva of patients with chronic back pain syndromes.” Anesth Analg 70, no. 1 (January 1990): 63–67. https://doi.org/10.1213/00000539-199001000-00010.
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    • Jamison, R. N., T. Sbrocco, and W. C. Parris. “The influence of physical and psychosocial factors on accuracy of memory for pain in chronic pain patients.” Pain 37, no. 3 (June 1989): 289–94. https://doi.org/10.1016/0304-3959(89)90193-0.
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    • Kambam, J. R., B. Horton, W. C. Parris, S. A. Hyman, M. L. Berman, and B. V. Sastry. “Pseudocholinesterase activity in human cerebrospinal fluid.” Anesth Analg 68, no. 4 (April 1989): 486–88.
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    • Kambam, J. R., J. Hammon, W. C. Parris, and F. M. Lupinetti. “Intrapleural analgesia for post-thoracotomy pain and blood levels of bupivacaine following intrapleural injection.” Can J Anaesth 36, no. 2 (March 1989): 106–9. https://doi.org/10.1007/BF03011428.
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    • Parris, W. C. “Reverse Sellick maneuver.” Anesth Analg 68, no. 3 (March 1989): 423. https://doi.org/10.1213/00000539-198903000-00061.
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    • Graham, S. G., A. M. Burgess, J. Kambam, W. Parris, J. J. Franks, B. V. R. Sastry, R. Naukam, and B. E. Smith. “Metoclopramide inhibits plasma cholinesterase.” Canadian Journal of Anaesthesia 36, no. 6 (1989): 729–30.
    • Kambam, J., W. Parris, J. J. Franks, B. V. R. Sastry, R. Naukam, and B. E. Smith. “Reply.” Canadian Journal of Anaesthesia 36, no. 6 (1989): 729–30. https://doi.org/10.1007/BF03005434.
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    • Parris, W. C. V., and W. D. Dettbarn. “Muscle atrophy following bupivacaine trigger point injection.” Anesthesiology Review 16, no. 3 (January 1, 1989): 50–54.
    • Jamison, R. N., D. A. Matt, and W. C. Parris. “Treatment outcome in low back pain patients: do compensation benefits make a difference?” Orthop Rev 17, no. 12 (December 1988): 1210–15.
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    • Kambam, J. R., B. F. Horton, W. C. Parris, and D. A. Holaday. “Effect of sevoflurane on P50 and on measurement of oxygen tension.” J Clin Monit 4, no. 4 (October 1988): 261–63. https://doi.org/10.1007/bf01617323.
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    • Parris, W. C., S. Lin, and W. Frist. “Use of stellate ganglion blocks for chronic chest pain associated with primary pulmonary hypertension.” Anesth Analg 67, no. 10 (October 1988): 993–95.
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    • Kambam, J. R., W. C. Parris, J. J. Franks, B. V. Sastry, R. Naukam, and B. E. Smith. “The inhibitory effect of metoclopramide on plasma cholinesterase activity.” Can J Anaesth 35, no. 5 (September 1988): 476–78. https://doi.org/10.1007/BF03026894.
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    • Parris, W. C., J. Kambam, and B. Adkins. “Typical and atypical presentation of malignant hyperpyrexia in nonwhite patients.” Anesth Prog 35, no. 5 (September 1988): 208–11.
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    • Parris, W. C., J. R. Kambam, S. Blanks, and R. Dean. “The effect of intentional hemodilution on P50.” J Cardiovasc Surg (Torino) 29, no. 5 (September 1988): 560–62.
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    • Parris, W. C., and W. D. Dettbarn. “Muscle atrophy following nerve block therapy.” Anesthesiology 69, no. 2 (August 1988): 289. https://doi.org/10.1097/00000542-198808000-00037.
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    • Parris, W. C., J. A. Oates, J. Kambam, R. Shmerling, and J. F. Sawyers. “Pre-treatment with somatostatin in the anaesthetic management of a patient with carcinoid syndrome.” Can J Anaesth 35, no. 4 (July 1988): 413–16. https://doi.org/10.1007/BF03010865.
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    • Gaukroger, P. B., P. Brownridge, and W. C. V. Parris. “Epidural blood patch in treatment of chronic headache.” Canadian Journal of Anaesthesia 35, no. 3 (May 1, 1988): 322–23. https://doi.org/10.1007/BF03010642.
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    • Jamison, R. N., D. L. Rock, and W. C. Parris. “Empirically derived Symptom Checklist 90 subgroups of chronic pain patients: a cluster analysis.” J Behav Med 11, no. 2 (April 1988): 147–58. https://doi.org/10.1007/bf00848262.
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    • Parris, W. C., D. Matt, R. N. Jamison, and W. Maxson. “Anxiety and postoperative recovery in ambulatory surgery patients.” Anesth Prog 35, no. 2 (March 1988): 61–64.
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    • Jamison, R. N., D. A. Matt, and W. C. Parris. “Effects of time-limited vs unlimited compensation on pain behavior and treatment outcome in low back pain patients.” J Psychosom Res 32, no. 3 (1988): 277–83. https://doi.org/10.1016/0022-3999(88)90069-4.
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    • Jamison, R. N., T. Sbrocco, and W. C. Parris. “The influence of problems with concentration and memory on emotional distress and daily activities in chronic pain patients.” Int J Psychiatry Med 18, no. 2 (1988): 183–91. https://doi.org/10.2190/ftr1-f9vx-cb8t-wpmc.
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    • Lipman, J. J., B. Blumenkopf, and W. C. Parris. “Chronic pain assessment using heat beam dolorimetry.” Pain 30, no. 1 (July 1987): 59–67. https://doi.org/10.1016/0304-3959(87)90083-2.
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    • Parris, W. C. “Use of epidural blood patch in treating chronic headache: report of six cases.” Can J Anaesth 34, no. 4 (July 1987): 403–6. https://doi.org/10.1007/BF03010144.
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    • Jamison, R. N., J. J. Vasterling, and W. C. Parris. “Use of sensory descriptors in assessing chronic pain patients.” J Psychosom Res 31, no. 5 (1987): 647–52. https://doi.org/10.1016/0022-3999(87)90044-4.
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    • Jamison, R. N., W. C. Parris, and W. S. Maxson. “Psychological factors influencing recovery from outpatient surgery.” Behav Res Ther 25, no. 1 (1987): 31–37. https://doi.org/10.1016/0005-7967(87)90112-4.
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    • Parris, W. C. V., H. Kirshner, and E. Brin. “Herpes zoster ophthalmicus associated with contralateral hemiplegia.” Clinical Journal of Pain 3, no. 4 (January 1, 1987): 219–22. https://doi.org/10.1097/00002508-198712000-00007.
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    • Parris, W. C. V., and J. Kamban. “Anesthetic considerations for the patient with polymyositis.” Anesthesiology Review 14, no. 2 (January 1, 1987): 42–46.
    • Parris, W. C., R. N. Jamison, and J. J. Vasterling. “Follow-up study of a multidisciplinary pain center.” J Pain Symptom Manage 2, no. 3 (1987): 145–51. https://doi.org/10.1016/s0885-3924(87)80073-8.
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    • Parris, W. C. “Chronic pain management: a logical approach.” J Tenn Med Assoc 79, no. 11 (November 1986): 683–87.
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    • Parris, W. C. “Use of the epidural blood patch in the treatment of chronic headaches.” Anesthesiology 65, no. 3 (September 1986): 344.
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    • Parris, W. C. V., and B. E. Smith. “Management of mastocytosis in pregnancy.” Anesthesiology Review 13, no. 4 (January 1, 1986): 17–23.
    • Parris, W. C., and R. N. Jamison. “Chronic pain in adults with a history of childhood sexual abuse.” J Tenn Med Assoc 78, no. 8 (August 1985): 493–95.
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    • Parris, W. C. V. “Nerve block therapy.” Clinics in Anaesthesiology 3, no. 1 (January 1, 1985): 93–109.
    • Parris, W. C. “Management of post-herpetic neuralgia.” J Tenn Med Assoc 77, no. 10 (October 1984): 575–78.
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    • Parris, W. C. V., M. R. Goldberg, A. S. Hollister, and D. Robertson. “Anesthetic management in autonomic dysfunction.” Anesthesiology Review 11, no. 6 (January 1, 1984): 17–23.
    • Scott, H. W., W. C. Parris, P. C. Sandidge, J. A. Oates, and L. J. Roberts. “Hazards in operative management of patients with systemic mastocytosis.” Ann Surg 197, no. 5 (May 1983): 507–14. https://doi.org/10.1097/00000658-198305000-00002.
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    • Parris, W. C., and C. W. Quimby. “Anesthetic considerations for the patient with homocystinuria.” Anesth Analg 61, no. 8 (August 1982): 708–10.
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    • Parris, W. C., and A. C. Johnson. “Tracheomegaly.” Anesthesiology 56, no. 2 (February 1982): 141–43. https://doi.org/10.1097/00000542-198202000-00009.
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    • Gerlock, A. J., R. C. MacDonell, W. C. Parris, R. E. Richie, M. B. Tallent, H. K. Johnson, B. I. Turner, and G. D. Niblack. “Partial splenic embolization: an alternative to splenectomy in the treatment of hypersplenism.” J Tenn Med Assoc 74, no. 2 (February 1981): 126–28.
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    • Parris, W. C., A. J. Gerlock, and R. C. MacDonell. “Intra-arterial chloroprocaine for the control of pain associated with partial splenic embolization.” Anesth Analg 60, no. 2 (February 1981): 112–15.
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    • Parris, W. C. V. “Management of tetanus.” Anesthesiology Review 8, no. 5 (January 1, 1981): 17–25.
    • Parris, W. C. V., P. C. Sandidge, and G. Petrinely. “Anesthetic management of mastocytosis.” Anesthesiology Review 8, no. 12 (January 1, 1981): 32–35.
    • MacDonell, R. C., A. J. Gerlock, W. C. Parris, R. E. Richie, M. B. Tallent, H. K. Johnson, B. I. Turner, and G. D. Niblack. “Therapeutic angiography in renal transplant complications.” Proc Clin Dial Transplant Forum 10 (1980): 145–49.
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