Overview
Dr. Xi Chen is dedicated to being a clinician-scientist who provides great medical and surgical care to patients with vitreoretinal diseases, with a research focus in retinal neurovascular development and disease. Her current research interest is studying human retinal and vascular development and their coordination using advanced imaging techniques.
Dr. Chen's basic science training in neural development gives her a unique perspective in her research in human retinal neurovascular development and disease. She hopes to eventually bring the information gathered from the bedside back to the laboratory in order to develop strategies to improve care of premature infants, and pediatric and adult patients with retinal vascular diseases.
She is very excited to work closely with Dr. Cynthia Toth and Dr. Joseph Izatt, who have pioneered the world in the development of bedside OCT technology and its adaptation for pediatric use. The many gifted clinician-scientists at Duke Eye Center as mentors and role models will also be key to Dr. Chen's research development.
Dr. Chen arrived at Duke for fellowship training in vitreoretinal surgery after spending eight years in Boston. She says that she loved her mentors, the staff and the patients at Duke and found the environment to be warm, caring, fun and collaborative. She is grateful to work alongside colleagues and staff who work hard and go out of their way to provide the best possible care to patients.
Dr. Chen's basic science training in neural development gives her a unique perspective in her research in human retinal neurovascular development and disease. She hopes to eventually bring the information gathered from the bedside back to the laboratory in order to develop strategies to improve care of premature infants, and pediatric and adult patients with retinal vascular diseases.
She is very excited to work closely with Dr. Cynthia Toth and Dr. Joseph Izatt, who have pioneered the world in the development of bedside OCT technology and its adaptation for pediatric use. The many gifted clinician-scientists at Duke Eye Center as mentors and role models will also be key to Dr. Chen's research development.
Dr. Chen arrived at Duke for fellowship training in vitreoretinal surgery after spending eight years in Boston. She says that she loved her mentors, the staff and the patients at Duke and found the environment to be warm, caring, fun and collaborative. She is grateful to work alongside colleagues and staff who work hard and go out of their way to provide the best possible care to patients.
Current Duke Appointments & Affiliations
Associate Professor of Ophthalmology
·
2023 - Present
Ophthalmology, Vitreoretinal Diseases & Surgery,
Ophthalmology
Recent Scholarly Works
Imaging infants and children with investigational handheld optical coherence tomography with widefield lens: a pilot study.
Journal article Graefes Arch Clin Exp Ophthalmol · July 2026 Full text Link to item CiteVery Preterm Infant Retinal Microanatomy at 36 Weeks' Postmenstrual Age and 2-Year Neurodevelopment.
Journal article JAMA Ophthalmol · June 4, 2026 IMPORTANCE: If noninvasive optical coherence tomography (OCT) retinal imaging could predict 2-year neurodevelopment of very preterm (VPT; <32 weeks' gestational age) infants in neonatal intensive care, it might help to guide management. OBJECTIVE: To evalu ... Full text Link to item CiteExudative retinopathy from retinal vasoproliferative tumor refractory to aflibercept treated with faricimab-svoa
Journal article American Journal of Ophthalmology Case Reports · June 1, 2026 Purpose To report a case of exudative retinopathy secondary to retinal vasoproliferative tumor (RVPT) refractory to aflibercept treated with faricimab-svoa (faricimab). Principal results A 43-year-old female presented with an exudative and hemorrhagic lesi ... Full text CiteRecent Grants
Duke Ophthalmology Mentored Physician Scientist Program
Inst. Training Prgm or CMEProgram Coordinator · Awarded by National Institutes of Health · 2026 - 2031Analyzing Retinal Microanatomy in Retinopathy of Prematurity to Improve Care
ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2026 - 2030Engineering three-dimensional perfusable microphysiological models of the human inner blood-retina barrier
ResearchCo Investigator · Awarded by National Eye Institute · 2024 - 2027View All Grants
Education
Harvard Medical School ·
2011
M.D.
Johns Hopkins University, School of Medicine ·
2007
Ph.D.
Peking University (China) ·
2001
B.S.