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Ryohei Yasuda

Adjunct Assistant Professor in the Department of Neurobiology
Box 3209 Med Ctr, Durham, NC 27710
401D Bryan Research Bldg, Box 3209, Durham, NC 27710

Selected Publications

Studying signal transduction in single dendritic spines.

Journal Article Cold Spring Harb Perspect Biol · October 1, 2012 Many forms of synaptic plasticity are triggered by biochemical signaling that occurs in small postsynaptic compartments called dendritic spines, each of which typically houses the postsynaptic terminal associated with a single glutamatergic synapse. Recent ... Full text Link to item Cite

The mechanisms underlying the spatial spreading of signaling activity.

Journal Article Curr Opin Neurobiol · April 2011 During the induction of plasticity of dendritic spines, many intracellular signaling pathways are spatially and temporally regulated to co-ordinate downstream cellular processes in different dendritic micron-domains. Recent advent of imaging technology bas ... Full text Link to item Cite

Optogenetic probes.

Journal Article Brain Cell Biol · August 2008 Full text Link to item Cite

Imaging spatiotemporal dynamics of neuronal signaling using fluorescence resonance energy transfer and fluorescence lifetime imaging microscopy.

Journal Article Curr Opin Neurobiol · October 2006 The spatiotemporal localization of neuronal signaling is important for triggering neuronal responses in specific locations at precise times. Fluorescence resonance energy transfer imaging enables measurement of spatiotemporal dynamics of signaling activity ... Full text Link to item Cite

Supersensitive Ras activation in dendrites and spines revealed by two-photon fluorescence lifetime imaging.

Journal Article Nat Neurosci · February 2006 To understand the biochemical signals regulated by neural activity, it is necessary to measure protein-protein interactions and enzymatic activity in neuronal microcompartments such as axons, dendrites and their spines. We combined two-photon excitation la ... Full text Link to item Cite