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Ying Xian

Adjunct Associate Professor in the Department of Neurology
Neurology, Neurocritical Care
200 Morris St, Duke Box 3850, Durham, NC 27701
PO Box 17969, Durham, NC 27715

Current Appointments & Affiliations


Adjunct Associate Professor in the Department of Neurology · 2021 - Present Neurology, Neurocritical Care, Neurology

Recent Publications


Incidence and prevalence of dementia among US Medicare beneficiaries, 2015-21: population based study.

Journal Article BMJ · May 20, 2025 OBJECTIVE: To determine the incidence and prevalence of dementia in a nationally representative cohort of US Medicare beneficiaries, stratified by important subgroups. DESIGN: Population based study. SETTING: Nationwide study between 2015 and 2021. PARTICI ... Full text Link to item Cite

Short-Term Safety and Effectiveness for Tenecteplase and Alteplase in Acute Ischemic Stroke.

Journal Article JAMA Netw Open · March 3, 2025 IMPORTANCE: Tenecteplase is an alternative to alteplase for emergency treatment of acute ischemic stroke. However, limited data are available comparing their clinical effectiveness in routine clinical practice. OBJECTIVE: To compare short-term effectivenes ... Full text Link to item Cite

Prourokinase vs Standard Care for Patients With Mild Ischemic Stroke: The PUMICE Randomized Clinical Trial.

Journal Article JAMA Neurol · March 1, 2025 IMPORTANCE: Trials have not demonstrated superiority of alteplase or tenecteplase vs standard care in patients with mild stroke and have raised safety concerns. Prourokinase is an alternative fibrinolytic that may have a favorable safety profile, and the b ... Full text Link to item Cite
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Recent Grants


NINDS Research Education Programs for Residents and Fellows in Neurosurgery

Inst. Training Prgm or CMEMentor · Awarded by National Institute of Neurological Disorders and Stroke · 2009 - 2025

Balancing Risks and Benefits of Direct Oral Anticoagulants in Older Ischemic Stroke Patients with Atrial Fibrillation

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2020 - 2021

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