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Michael Rod Zalutsky

Jonathan Spicehandler, M.D. Distinguished Professor of Neuro Oncology, in the School of Medicine
Radiology
Box 3808 Med Ctr, Durham, NC
311 Research Drive, 161H Bryan Res Bldg, Durham, NC 27710

Selected Grants


Targeting neuroendocrine cells in prostate cancer with small molecule and targeted radionuclide therapies

ResearchCo Investigator · Awarded by Prostate Cancer Foundation · 2023 - 2025

PSMAi-PARPi combination agents for the targeted Auger and alpha therapy of metastatic castration-resistant prostate cancer

ResearchCo Investigator · Awarded by National Institutes of Health · 2022 - 2024

Small Molecule PSMA-Targeted Alpha Therapy

ResearchPrincipal Investigator · Awarded by Johns Hopkins University · 2014 - 2024

Evaluating the Behavior of Novel IL13Ralpha2-directed T cell Engager for GBM Treatment

ResearchPrincipal Investigator · Awarded by Northwestern University · 2021 - 2023

Flourine-18 labeled MDM2 antagonists for PET imaging

ResearchCo Investigator · Awarded by National Institutes of Health · 2020 - 2023

Targeting neuroendocrine cells in prostate cancer with small molecule and targeted radionuclide therapies

ResearchCo Investigator · Awarded by Prostate Cancer Foundation · 2023 - 2025

PSMAi-PARPi combination agents for the targeted Auger and alpha therapy of metastatic castration-resistant prostate cancer

ResearchCo Investigator · Awarded by National Institutes of Health · 2022 - 2024

Small Molecule PSMA-Targeted Alpha Therapy

ResearchPrincipal Investigator · Awarded by Johns Hopkins University · 2014 - 2024

Evaluating the Behavior of Novel IL13Ralpha2-directed T cell Engager for GBM Treatment

ResearchPrincipal Investigator · Awarded by Northwestern University · 2021 - 2023

Flourine-18 labeled MDM2 antagonists for PET imaging

ResearchCo Investigator · Awarded by National Institutes of Health · 2020 - 2023

CA181292 Targeted Gold Nanoparticles (AuNPs) for Potent Alpha-Particle Radiotherapy of Brain Cancer

ResearchCo-Mentor · Awarded by United States Army Medical Research Acquisition Activity · 2019 - 2022

Astatine And Iodine Radiolabeled Monoclonal Antibodies

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 1985 - 2021

Enhancing Radionuclide Production Capabilities at the Duke University Medical Center Cyclotron with a Focus on Astatine-211

ResearchPrincipal Investigator · Awarded by Department of Energy · 2019 - 2021

Image-guided Dosimetry for Injectable Brachytherapy based on Elastin-like Polypeptide Nanoparticles

ResearchCo Investigator · Awarded by National Institutes of Health · 2017 - 2021

Labeling nanobodies with 18F residualizing labels for HER2 specific PET imaging

ResearchCo Investigator · Awarded by National Institutes of Health · 2015 - 2021

Systemically administrered EGRFvIII-targeted bispecific antibody as an immunotherapeutic for glioblastoma.

FellowshipCollaborator · Awarded by National Institutes of Health · 2015 - 2019

Novel Radiohalogenation Strategies for Enhancing Imaging and Targeted Radiotherapy with Ultrasmall Dual- Modality Silica Nanoparticles (C Dots)

ResearchPrincipal Investigator · Awarded by Memorial Sloan-Kettering Cancer Center · 2016 - 2018

Treating Melanoma with a Molecularly Engineered, Long Circulating Immunotoxin

ResearchCo Investigator · Awarded by National Institutes of Health · 2015 - 2018

Development of a Targeted Radionuclide Therapy for Triple Negative Breast Cancer

ResearchCo Investigator · Awarded by OncoTAb, Inc. · 2016 - 2017

Pediatric Brain Tumor Consortium

Clinical TrialCollaborator · Awarded by St. Jude Children's Research Hospital · 2014 - 2017

Imaging IDH1 Mutations in Glioma and Other Malignancies

ResearchCo Investigator · Awarded by National Institutes of Health · 2014 - 2016

Research Training In Neuro-Oncology

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 1998 - 2016

Thermally Triggered Multivalent Targeting of Tumors

ResearchCo Investigator · Awarded by National Institutes of Health · 2007 - 2016

Thermally Targeted Drug Delivery by Elastin Biopolymers

ResearchCo Investigator · Awarded by National Institutes of Health · 2002 - 2016

Local Radionuclide Delivery to Solid Tumors by Injectible Biopolymer

ResearchCo Investigator · Awarded by National Institutes of Health · 2009 - 2016

Modulation of the blood-tumor barrier through targeted suppression of claudin 5

ResearchCollaborator · Awarded by National Institutes of Health · 2011 - 2013

Cross-disciplinary Training in Medical Physics

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2007 - 2013

Brain Tumors - Immunological and Biological Studies

ResearchInvestigator · Awarded by National Institutes of Health · 2001 - 2013

Small Animal PET / CT Molecular Imaging

EquipmentMajor User · Awarded by National Institutes of Health · 2011 - 2012

Radionuclide-based Molecular Imaging of the DNA Repair Protein AGT

ResearchCo Investigator · Awarded by National Institutes of Health · 2009 - 2011

Astatine-211 Radiochemistry: The Development of Methodologies for High Activity Level Radio-Synthesis

ResearchPrincipal Investigator · Awarded by Department of Energy · 2008 - 2010

Research Training In Neuro-Oncology

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2005 - 2010

Thermally-Induced Intra-Articular Drug Delivery System

ResearchCo Investigator · Awarded by National Institutes of Health · 2006 - 2009

Imaging of O6-Alkylguianine-DNA Alkyltransferase

ResearchConsultant · Awarded by National Institutes of Health · 2002 - 2007

Targeted Radiotherapeutics: Chemical and Biological Aspects

ResearchPrincipal Investigator · Awarded by Department of Energy · 2004 - 2006

Astatine-211 & Radioiodine Labeled Octreotide Conjugates

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2001 - 2006

Anti-Tenascin Antibody Constructs

ResearchPrincipal Investigator · Awarded by Department of Energy · 1995 - 2005

GCRC CAP

ResearchMentor · Awarded by National Institutes of Health · 2000 - 2005

Higher Oxidation State Astatine-211 Radiopharmaceuticals

ResearchCo Investigator · Awarded by National Institutes of Health · 2003 - 2005

Molecular Imaging Center Planning Grant

ResearchInvestigator · Awarded by National Institutes of Health · 2000 - 2004

Astatine And Iodine Radiolabeled Monoclonal Antibodies

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 1999 - 2004

Development of Novel Tumor Imaging Agents

ResearchCollaborator · Awarded by National Institutes of Health · 2000 - 2003

Radiolabeled Monoclonal Antibodies And Hyperthermia

ResearchPrincipal Investigator · Awarded by Department of Energy · 1998 - 2001

Brain Tumors--Immunological and Biological Studies

ResearchInvestigator · Awarded by National Institutes of Health · 1976 - 2001

Brain Tumors - Immunological And Biological Studies

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 1997 - 1999

Src On Primary And Matastatic Tumors Of The Cns

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 1994 - 1999

Astatine And Iodine Radiolabeled Monoclonal Antibodies

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 1994 - 1999

Src On Primary And Metastatic Tumors Of The Cns

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 1997 - 1999

Astatine And Iodine Radiolabeled Monoclonal Antibodies

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 1993 - 1999

Astatine And Iodine Radiolabeled Monoclonal Antibodies

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 1985 - 1999

Comprehensive Cancer Center Core Support Grant

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 1976 - 1998

Cancer Center Core Support Grant

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 1976 - 1998

Comprehensive Cancer Center Core Support Grant

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 1976 - 1998

Positron Emission Imaging Of Tumors Using Monoclonal Antib

ResearchPrincipal Investigator · Awarded by Department of Energy · 1995 - 1998

Mibg And Analogs For Diagnosis And Therapy

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 1993 - 1998

Recombinant Anti-Tenascin Antibody Constructs

ResearchPrincipal Investigator · Awarded by Department of Energy · 1995 - 1998

Positron Tomographic Imaging Of Tumors Using Monoclonal An

ResearchPrincipal Investigator · Awarded by Department of Energy · 1993 - 1995

Positron Emission Tomography Imaging Of Tumors Using Monoc

ResearchPrincipal Investigator · Awarded by Department of Energy · 1992 - 1995

Intrathecal Therapy Of Melanoma Neoplastic Meningitis

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 1993 - 1995

Positron Emission Tom0graphic Imaging Of Tumors Using Mono

ResearchPrincipal Investigator · Awarded by Department of Energy · 1992 - 1995

Positron Emission Tomographic Imaging Of Tumors Using Mono

ResearchPrincipal Investigator · Awarded by Department of Energy · 1989 - 1995

Specific Applications Of Pet And Mrs In Brain Tumors

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 1994 - 1995

Scor In Coronary And Vascular Diseases

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 1992 - 1994

Src On Malignant Human Gliomas And Medulloblastomas

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 1993 - 1994

Cancer And Leukemia Group B Statistical Center

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 1992 - 1993

Positron Emission Tomagraphic Imaging Of Tumors Using Mono

ResearchPrincipal Investigator · Awarded by Department of Energy · 1991 - 1992

Positron Emission Tomagraphic Imaging Of Tumors Using ...

ResearchPrincipal Investigator · Awarded by Department of Education · 1990 - 1992

Positron Emission Tomogrphic Imaging Of Tumors Using Monoc

ResearchPrincipal Investigator · Awarded by Department of Energy · 1989 - 1992

Radiotherapy Using Monoclonal Antibodies And Astatine

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 1987 - 1989

External Relationships


  • Z-Alpha, Inc
  • cereius
  • precision molecular, inc

This faculty member (or a member of their immediate family) has reported outside activities with the companies, institutions, or organizations listed above. This information is available to institutional leadership and, when appropriate, management plans are in place to address potential conflicts of interest.