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Stefan Zauscher

Professor in the Thomas Lord Department of Mechanical Engineering and Materials Science
Thomas Lord Department of Mechanical Engineering and Materials Science
3385 Fciemas Building, Box 90300, Durham, NC 27708-0300
3385 Fciemas Building, Box 90300, Durham, NC 27708

Research Interests


Nano-mechanical and nano-tribological characterization (elasticity, friction, adhesion) of materials including organic thin films; self-assembled monolayers, polymeric gels, and cellulosics; Fabrication of polymeric nanostructures by scanning probe lithography; Colloidal probe and atomic force microscopy; Single molecule force spectroscopy applied to ligand-receptor binding; Biomolecular nano- and micro-sensors

Selected Grants


Molecular engineering of HA-based lubricants for articular cartilage

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2023 - 2028

University Training Program in Biomolecular and Tissue Engineering

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 1994 - 2027

Acquisition of a Photoelectron Spectrometer (XPS) for Fundamental and Applied Biomedical Research, Education and Training

EquipmentPrincipal Investigator · Awarded by North Carolina Biotechnology Center · 2024 - 2025

High-resolution characterization of biologically relevant soft materials

EquipmentCo Investigator · Awarded by Air Force Office of Scientific Research · 2024 - 2025

Local Polymer Interfacial Mechanics: Effect of Topological and Chemical NanoPatterning

ResearchCo-Principal Investigator · Awarded by National Science Foundation · 2021 - 2024

Molecular engineering of HA-based lubricants for articular cartilage

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2023 - 2028

University Training Program in Biomolecular and Tissue Engineering

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 1994 - 2027

Acquisition of a Photoelectron Spectrometer (XPS) for Fundamental and Applied Biomedical Research, Education and Training

EquipmentPrincipal Investigator · Awarded by North Carolina Biotechnology Center · 2024 - 2025

High-resolution characterization of biologically relevant soft materials

EquipmentCo Investigator · Awarded by Air Force Office of Scientific Research · 2024 - 2025

Local Polymer Interfacial Mechanics: Effect of Topological and Chemical NanoPatterning

ResearchCo-Principal Investigator · Awarded by National Science Foundation · 2021 - 2024

Acquisition of a VRS1250 Video-Rate Imaging Module for a Shared-Use Asylum-Cypher Atomic Force Microscope (AFM)

EquipmentMajor User · Awarded by North Carolina Biotechnology Center · 2023 - 2024

LUMICKS C-TRAP

EquipmentMajor User · Awarded by National Institutes of Health · 2022 - 2023

Acquisition of a Biacore T200 Surface Plasmon Resonance Instrument for Shared Use

EquipmentMajor User · Awarded by North Carolina Biotechnology Center · 2022 - 2023

The Graduate Diversity Enrichment Program (GDEP)

FellowshipPrincipal Investigator · Awarded by Burroughs Wellcome Fund · 2019 - 2021

In situ Enzymatic Synthesis of Aptamer Targeted Polynucleotide Drug Nanoparticles for Cancer Therapy (Year 2)

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2018 - 2021

Programming bacteria for materials fabrication

ResearchCo-Principal Investigator · Awarded by Office of Naval Research · 2015 - 2019

Collaborative Research: Supramolecular Materials by Nucleic Acid Block Copolymer Selfassembly

ResearchPrincipal Investigator · Awarded by National Science Foundation · 2014 - 2019

Self-assembled microporous networks for cell culture

ResearchCo-Principal Investigator · Awarded by EMD Millipore · 2017 - 2019

Microfluidic quartz resonator based blood plasma coagulation monitors

ResearchPrincipal Investigator · Awarded by Qatch Technologies LLC · 2017 - 2018

Research Triangle MRSEC Supplement to NSF 1121107

ResearchPrincipal Investigator · Awarded by National Science Foundation · 2011 - 2018

Triangle CEMRI

ResearchPrincipal Investigator · Awarded by National Science Foundation · 2011 - 2018

Texas State University PREM: Center on Interfaces in Materials

ResearchPrincipal Investigator · Awarded by Texas State University · 2012 - 2017

Programming bacteria for materials fabrication

ResearchCo Investigator · Awarded by Office of Naval Research · 2012 - 2015

Structural Biology and Biophysics Training Program

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 1994 - 2015

Surface Initiated Enzymatic Polymerization of DNA Nanostructures for Highly Amplified Sensing

ResearchCo Investigator · Awarded by National Science Foundation · 2010 - 2015

HIV-1 Neutralizing Antibody Binding to Viral Membrane Mimics

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2012 - 2015

GOALI Collaborative Research: Engineering Magnetorheological (MR) Fluids

ResearchPrincipal Investigator · Awarded by National Science Foundation · 2010 - 2013

GOALI: Engineering Magnetorheological Fluids by Controlling Nonmagnetic Particle Interactions

ResearchPrincipal Investigator · Awarded by National Science Foundation · 2009 - 2013

NSF MRI Research Triangle X-Ray Scattering Instrumentation: SAXS/WAXS/GISAXS

EquipmentPrincipal Investigator · Awarded by National Science Foundation · 2012 - 2013

AVS Conference: Topical Conference on Marine Biofouling at AVS 57th International Symposium, Albequerque, New Mexico. October 2010

ConferencePrincipal Investigator · Awarded by Office of Naval Research · 2010 - 2011

Engineering a Localized pH Switch at the Solid-Liquid Interface

ResearchCo Investigator · Awarded by National Science Foundation · 2008 - 2011

AVS-BID Conference Speaker Support 2010

ConferencePrincipal Investigator · Awarded by Army Research Office · 2010 - 2011

AVS Conference: Biomaterials Interfaces Division

FellowshipPrincipal Investigator · Awarded by National Science Foundation · 2009 - 2010

Imaginary Magnetic Tweezers for Biophysical Force Measurements

ResearchCo-Principal Investigator · Awarded by National Science Foundation · 2006 - 2010

NIRT: Hierarchical Bionanomanufacturing

ResearchCo-Principal Investigator · Awarded by National Science Foundation · 2006 - 2010

Design and Fabrication of Quartz Crystal Resonators for Nano-Mechano-Chemistry Research: An Interdisciplinary Engineering Design Experience for Undergraduate Students

Inst. Training Prgm or CMEPrincipal Investigator · Awarded by Lord Foundation of North Carolina · 2009 - 2010

CAREER: Fabrication and Characterization of Stimulus-Responsive Polymer Nanostructures

ResearchPrincipal Investigator · Awarded by National Science Foundation · 2003 - 2010

Adult Stem Cell Enrichment via Biomechanical Characterization

ResearchCollaborator · Awarded by National Institutes of Health · 2007 - 2009

Training in Biomolecular and Tissue Engineering

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2003 - 2009

A Nanoengineering Design Experience for Engineering Students at the Museum of Life and Science in Durham

Institutional SupportPrincipal Investigator · Awarded by Lord Foundation of North Carolina · 2008 - 2009

International Symposium on Biomaterials Interfaces

ConferencePrincipal Investigator · Awarded by Army Research Office · 2008 - 2009

Effect of Shockwaves on the Biochemical and Biomechanical Function of Cells (supplement)

ResearchPrincipal Investigator · Awarded by Army Research Office · 2007 - 2009

Synthesis, Mechanics, and Modeling of Stimulus Responsive Polymers for Engineering Applications

ResearchPrincipal Investigator · Awarded by Army Research Office · 2006 - 2008

Collaborative Research: Surface and Actuation Kinetics of Stimulus-Responsive Hydrogels

ResearchCo-Principal Investigator · Awarded by National Science Foundation · 2003 - 2007

Biomolecular and Polymeric Nanostructures and Interfaces

ConferencePrincipal Investigator · Awarded by Army Research Office · 2006 - 2006

Nanofabrication of Polymer-Functionalized Surfaces Using Scanning Probe Lithography

ResearchCo-Principal Investigator · Awarded by National Science Foundation · 2002 - 2006

Synthesis, Mechanics, and Modeling of Stimulus Responsive Polymers for Engineering Applications

ResearchPrincipal Investigator · Awarded by Army Research Office · 2002 - 2006

Enhanced AFM-Imaging of Soft Nanostructures through Q-Control

ResearchPrincipal Investigator · Awarded by Lord Foundation of North Carolina · 2002 - 2005

Acquisition of an Imaging XPS for Materials Research and Training

EquipmentCo-Principal Investigator · Awarded by National Science Foundation · 2002 - 2004

Development and Construction of Single Molecule Spectrometers for Research and Student Training

EquipmentPrincipal Investigator · Awarded by National Science Foundation · 2001 - 2003

Development and Construction of a High-resolution, Single-axis Atomic Force Microscope for Research and Student Training

ResearchPrincipal Investigator · Awarded by Lord Foundation of North Carolina · 2001 - 2002

External Relationships


  • Qatch Technologies

This faculty member (or a member of their immediate family) has reported outside activities with the companies, institutions, or organizations listed above. This information is available to institutional leadership and, when appropriate, management plans are in place to address potential conflicts of interest.