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Yi Zeng

Professor in Medicine
Medicine, Geriatrics and Palliative Care
Duke Box 3003, Durham, NC 27710
Room 1506, Duke South, Durham, NC 27710

Overview


(1) Socioeconomic, behavior, environmental and genetic determinants of healthy aging and healthy longevity;
(2) Factors related to elderly disability and mental health;
(3) Methods of family households and elderly living arrangements forecasting/analysis and their applications in health services and socioeconomic planning, and market studies;
(4) Policy analysis in population aging, social welfare, retirement, and fertility transitions.

Current Appointments & Affiliations


Professor in Medicine · 2006 - Present Medicine, Geriatrics and Palliative Care, Medicine
Senior Fellow in the Center for the Study of Aging and Human Development · 2006 - Present Center for the Study of Aging and Human Development, Institutes and Centers
Faculty Research Scholar of DuPRI's Population Research Center · 2010 - Present Duke Population Research Center, Duke Population Research Institute
Faculty Research Scholar of DuPRI's Center for Population Health & Aging · 2011 - Present Center for Population Health & Aging, Duke Population Research Institute

Recent Publications


Development and Validation of the Disability Index Among Older Adults.

Journal Article J Gerontol A Biol Sci Med Sci · January 26, 2023 BACKGROUND: With the rapid population aging, the challenge to provide care for disabled older adults is becoming bigger. This study aims to develop the Disability Index (DI) to assess disability to indicate care needs, and we evaluated the reliability and ... Full text Open Access Link to item Cite

Comparing Effects of FOXO3 and Residing in Urban Areas on Longevity: A Gene-Environment Interaction Study.

Journal Article J Gerontol A Biol Sci Med Sci · August 12, 2022 Forkhead box O3 (FOXO3) is a candidate longevity gene. Urban residents are also positively associated with longer life expectancy. We conducted a gene-environment interaction to assess the synergistic effect of FOXO3 and urban/rural environments on mortali ... Full text Link to item Cite

Sex Difference and Interaction of SIRT1 and FOXO3 Candidate Longevity Genes on Life Expectancy: A 10-Year Prospective Longitudinal Cohort Study.

Journal Article J Gerontol A Biol Sci Med Sci · August 12, 2022 SIRT1 and FOXO3 are both associated with longevity. Molecular biology research in many organisms (yeast, nematode worm Caenorhabditis elegans, and mice mammalian models) shows SIRT1 acts on the FOXO family of forkhead transcription factors to respond to ox ... Full text Link to item Cite
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Recent Grants


Behavior And Physiology In Aging

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 1999 - 2015

Demographic Analysis on Determinants of Healthy Longevity in China

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2004 - 2015

Duke-PKU Workshop on Comparative and Interdisciplinary Studies of Health Aging

ConferencePrincipal Investigator · Awarded by Josiah Charles Trent Memorial Foundation · 2006 - 2007

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Education, Training & Certifications


Free University of Brussels (Belgium) · 1986 Ph.D.