Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Ph.D., Peking Union Medical College (China) 1997
  • B.M., Shandong Medical University (China) 1988
• 

  Duke Appointment History

  • Assistant Professor of Medicine, Medicine, Cardiology, Medicine 2008 - 2013
• Research
• 

  Selected Grants

  • Gene Therapy for Long-Term Myocardial Protection awarded by National Institutes of Health 2003 - 2014
  • Genetically Altered Mesenchymal Stem Cell; Paracrine Effect on Neovascularization awarded by National Institutes of Health 2003 - 2014
  • Renin Gene Expression in Cardiovascular Regulation: Mechanisms of JG Hyperplasia awarded by National Institutes of Health 1985 - 2013
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Jayawardena, Tilanthi M., Bakytbek Egemnazarov, Elizabeth A. Finch, Lunan Zhang, J Alan Payne, Kumar Pandya, Zhiping Zhang, Paul Rosenberg, Maria Mirotsou, and Victor J. Dzau. “MicroRNA-mediated in vitro and in vivo direct reprogramming of cardiac fibroblasts to cardiomyocytes.” Circ Res 110, no. 11 (May 25, 2012): 1465–73. https://doi.org/10.1161/CIRCRESAHA.112.269035.
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    • He, Wei, Lunan Zhang, Aiguo Ni, Zhiping Zhang, Maria Mirotsou, Lan Mao, Richard E. Pratt, and Victor J. Dzau. “Exogenously administered secreted frizzled related protein 2 (Sfrp2) reduces fibrosis and improves cardiac function in a rat model of myocardial infarction.” Proc Natl Acad Sci U S A 107, no. 49 (December 7, 2010): 21110–15. https://doi.org/10.1073/pnas.1004708107.
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    • Huang, Jing, Zhiping Zhang, Jian Guo, Aiguo Ni, Arjun Deb, Lunan Zhang, Maria Mirotsou, Richard E. Pratt, and Victor J. Dzau. “Genetic modification of mesenchymal stem cells overexpressing CCR1 increases cell viability, migration, engraftment, and capillary density in the injured myocardium.” Circ Res 106, no. 11 (June 11, 2010): 1753–62. https://doi.org/10.1161/CIRCRESAHA.109.196030.
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    • Zhang, Zhiping, and Victor J. Dzau. “Angiotensin II type 1 receptor-associated protein is an endogenous inhibitor of angiotensin II type 1 receptor action in cardiac hypertrophy: role in check and balance.” Hypertension 55, no. 5 (May 2010): 1086–87. https://doi.org/10.1161/HYPERTENSIONAHA.110.150458.
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    • Zhang, Zhongyan, Arjun Deb, Zhiping Zhang, Alok Pachori, Wei He, Jian Guo, Richard Pratt, and Victor J. Dzau. “Secreted frizzled related protein 2 protects cells from apoptosis by blocking the effect of canonical Wnt3a.” J Mol Cell Cardiol 46, no. 3 (March 2009): 370–77. https://doi.org/10.1016/j.yjmcc.2008.11.016.
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    • Gnecchi, Massimiliano, Zhiping Zhang, Aiguo Ni, and Victor J. Dzau. “Paracrine mechanisms in adult stem cell signaling and therapy.” Circ Res 103, no. 11 (November 21, 2008): 1204–19. https://doi.org/10.1161/CIRCRESAHA.108.176826.
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    • Deb, Arjun, Bryce H. Davis, Jian Guo, Aiguo Ni, Jing Huang, Zhiping Zhang, Hui Mu, and Victor J. Dzau. “SFRP2 regulates cardiomyogenic differentiation by inhibiting a positive transcriptional autofeedback loop of Wnt3a.” Stem Cells 26, no. 1 (January 2008): 35–44. https://doi.org/10.1634/stemcells.2007-0475.
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    • Matsushita, Kenichi, Zhiping Zhang, Richard E. Pratt, and Victor J. Dzau. “Molecular mechanism of juxtaglomerular cell hyperplasia: a unifying hypothesis.” J Am Soc Hypertens 1, no. 3 (May 2007): 164–68. https://doi.org/10.1016/j.jash.2007.02.004.
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