Widespread dissemination of CTX-M-15 genotype extended-spectrum-β-lactamase-producing enterobacteriaceae among patients presenting to community hospitals in the southeastern United States.
Publication
, Journal Article
Chen, LF; Freeman, JT; Nicholson, B; Keiger, A; Lancaster, S; Joyce, M; Woods, CW; Cook, E; Adcock, L; Louis, S; Cromer, AL; Sexton, DJ; Anderson, DJ
Published in: Antimicrob Agents Chemother
2014
Extended-spectrum-β-lactamase (ESBL)-producing organisms are increasingly prevalent. We determined the characteristics of 66 consecutive ESBL-producing isolates from six community hospitals in North Carolina and Virginia from 2010 to 2012. Fifty-three (80%) ESBL-producing isolates contained CTX-M enzymes; CTX-M-15 was found in 68% of Escherichia coli and 73% of Klebsiella isolates. Sequence type 131 (ST131) was the commonest type of E. coli, accounting for 48% of CTX-M-15-producing and 66% of CTX-M-14-producing isolates. In conclusion, the CTX-M genotype and ST131 E. coli were common among ESBL isolates from U.S. community hospitals.
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Published In
Antimicrob Agents Chemother
DOI
EISSN
1098-6596
Publication Date
2014
Volume
58
Issue
2
Start / End Page
1200 / 1202
Location
United States
Related Subject Headings
- beta-Lactamases
- Virginia
- North Carolina
- Multilocus Sequence Typing
- Middle Aged
- Microbiology
- Klebsiella
- Humans
- Hospitals, Community
- Gene Expression
Citation
APA
Chicago
ICMJE
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NLM
Chen, L. F., Freeman, J. T., Nicholson, B., Keiger, A., Lancaster, S., Joyce, M., … Anderson, D. J. (2014). Widespread dissemination of CTX-M-15 genotype extended-spectrum-β-lactamase-producing enterobacteriaceae among patients presenting to community hospitals in the southeastern United States. Antimicrob Agents Chemother, 58(2), 1200–1202. https://doi.org/10.1128/AAC.01099-13
Chen, Luke F., Joshua T. Freeman, Brad Nicholson, Anna Keiger, Sarah Lancaster, Maria Joyce, Christopher W. Woods, et al. “Widespread dissemination of CTX-M-15 genotype extended-spectrum-β-lactamase-producing enterobacteriaceae among patients presenting to community hospitals in the southeastern United States.” Antimicrob Agents Chemother 58, no. 2 (2014): 1200–1202. https://doi.org/10.1128/AAC.01099-13.
Chen LF, Freeman JT, Nicholson B, Keiger A, Lancaster S, Joyce M, et al. Widespread dissemination of CTX-M-15 genotype extended-spectrum-β-lactamase-producing enterobacteriaceae among patients presenting to community hospitals in the southeastern United States. Antimicrob Agents Chemother. 2014;58(2):1200–2.
Chen, Luke F., et al. “Widespread dissemination of CTX-M-15 genotype extended-spectrum-β-lactamase-producing enterobacteriaceae among patients presenting to community hospitals in the southeastern United States.” Antimicrob Agents Chemother, vol. 58, no. 2, 2014, pp. 1200–02. Pubmed, doi:10.1128/AAC.01099-13.
Chen LF, Freeman JT, Nicholson B, Keiger A, Lancaster S, Joyce M, Woods CW, Cook E, Adcock L, Louis S, Cromer AL, Sexton DJ, Anderson DJ. Widespread dissemination of CTX-M-15 genotype extended-spectrum-β-lactamase-producing enterobacteriaceae among patients presenting to community hospitals in the southeastern United States. Antimicrob Agents Chemother. 2014;58(2):1200–1202.
Published In
Antimicrob Agents Chemother
DOI
EISSN
1098-6596
Publication Date
2014
Volume
58
Issue
2
Start / End Page
1200 / 1202
Location
United States
Related Subject Headings
- beta-Lactamases
- Virginia
- North Carolina
- Multilocus Sequence Typing
- Middle Aged
- Microbiology
- Klebsiella
- Humans
- Hospitals, Community
- Gene Expression