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Risk assessment to predict arterial and venous events in patients undergoing percutaneous coronary intervention.

Publication ,  Journal Article
Vardi, M; Piazza, G; Pencina, MJ; Burke, DA; Lei, L; Goldhaber, SZ; Cutlip, DE
Published in: Clin Appl Thromb Hemost
July 2014

Atherosclerosis and venous thromboembolism (VTE) share common risk factors. We set to assess the strength of the association between atherosclerosis risk factors and disease manifestation, and VTE, in patients with coronary artery disease undergoing percutaneous coronary intervention. We pooled data from 6 global randomized controlled trials assessing coronary stenting (ENDEAVOR and SIRIUS programs), developed separate risk scores to predict major adverse cardiac and cerebrovascular events (MACCEs: cardiac death, myocardial infarction, and stroke) and VTE, and compared their performance. The 5-year rates of MACCE and VTE were 10.8% and 2.04%, respectively. Selected predictors for MACCE performed equally well in predicting VTE (area under the receiver-operating characteristic curve [AUC] 0.651 vs 0.672), and selected predictors for VTE performed equally well in predicting MACCE (AUC 0.699 vs 0.620). Ejection fraction and age were associated with both MACCE and VTE. These findings support the concept of overlapping pathophysiology of VTE and atherothrombosis.

Duke Scholars

Published In

Clin Appl Thromb Hemost

DOI

EISSN

1938-2723

Publication Date

July 2014

Volume

20

Issue

5

Start / End Page

478 / 483

Location

United States

Related Subject Headings

  • Venous Thromboembolism
  • Stroke Volume
  • Stroke
  • Risk Assessment
  • Prospective Studies
  • Postoperative Complications
  • Percutaneous Coronary Intervention
  • Myocardial Infarction
  • Middle Aged
  • Male
 

Citation

APA
Chicago
ICMJE
MLA
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Vardi, M., Piazza, G., Pencina, M. J., Burke, D. A., Lei, L., Goldhaber, S. Z., & Cutlip, D. E. (2014). Risk assessment to predict arterial and venous events in patients undergoing percutaneous coronary intervention. Clin Appl Thromb Hemost, 20(5), 478–483. https://doi.org/10.1177/1076029613517166
Vardi, Moshe, Gregory Piazza, Michael J. Pencina, David A. Burke, Lanyu Lei, Samuel Z. Goldhaber, and Donald E. Cutlip. “Risk assessment to predict arterial and venous events in patients undergoing percutaneous coronary intervention.Clin Appl Thromb Hemost 20, no. 5 (July 2014): 478–83. https://doi.org/10.1177/1076029613517166.
Vardi M, Piazza G, Pencina MJ, Burke DA, Lei L, Goldhaber SZ, et al. Risk assessment to predict arterial and venous events in patients undergoing percutaneous coronary intervention. Clin Appl Thromb Hemost. 2014 Jul;20(5):478–83.
Vardi, Moshe, et al. “Risk assessment to predict arterial and venous events in patients undergoing percutaneous coronary intervention.Clin Appl Thromb Hemost, vol. 20, no. 5, July 2014, pp. 478–83. Pubmed, doi:10.1177/1076029613517166.
Vardi M, Piazza G, Pencina MJ, Burke DA, Lei L, Goldhaber SZ, Cutlip DE. Risk assessment to predict arterial and venous events in patients undergoing percutaneous coronary intervention. Clin Appl Thromb Hemost. 2014 Jul;20(5):478–483.
Journal cover image

Published In

Clin Appl Thromb Hemost

DOI

EISSN

1938-2723

Publication Date

July 2014

Volume

20

Issue

5

Start / End Page

478 / 483

Location

United States

Related Subject Headings

  • Venous Thromboembolism
  • Stroke Volume
  • Stroke
  • Risk Assessment
  • Prospective Studies
  • Postoperative Complications
  • Percutaneous Coronary Intervention
  • Myocardial Infarction
  • Middle Aged
  • Male