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Liver transplantation in an adolescent with acute liver failure from acute lymphoblastic leukemia.

Publication ,  Journal Article
Reddi, DM; Barbas, AS; Castleberry, AW; Rege, AS; Vikraman, DS; Brennan, TV; Ravindra, KV; Collins, BH; Sudan, DL; Lagoo, AS; Martin, AE
Published in: Pediatr Transplant
March 2014

The most common identifiable causes of acute liver failure in pediatric patients are infection, drug toxicity, metabolic disease, and autoimmune processes. In many cases, the etiology of acute liver failure cannot be determined. Acute leukemia is an extremely rare cause of acute liver failure, and liver transplantation has traditionally been contraindicated in this setting. We report a case of acute liver failure in a previously healthy 15-yr-old male from pre-B-cell acute lymphoblastic leukemia. He underwent liver transplantation before the diagnosis was established, and has subsequently received chemotherapy for pre-B-cell acute lymphoblastic leukemia. He is currently alive 31 months post-transplantation. The published literature describing acute lymphoblastic leukemia as a cause of acute liver failure is reviewed.

Duke Scholars

Published In

Pediatr Transplant

DOI

EISSN

1399-3046

Publication Date

March 2014

Volume

18

Issue

2

Start / End Page

E57 / E63

Location

Denmark

Related Subject Headings

  • Treatment Outcome
  • Tissue Donors
  • Surgery
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma
  • Male
  • Liver Transplantation
  • Liver Function Tests
  • Liver Failure, Acute
  • Liver
  • Leukemia, B-Cell
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Reddi, D. M., Barbas, A. S., Castleberry, A. W., Rege, A. S., Vikraman, D. S., Brennan, T. V., … Martin, A. E. (2014). Liver transplantation in an adolescent with acute liver failure from acute lymphoblastic leukemia. Pediatr Transplant, 18(2), E57–E63. https://doi.org/10.1111/petr.12221
Reddi, D. M., A. S. Barbas, A. W. Castleberry, A. S. Rege, D. S. Vikraman, T. V. Brennan, K. V. Ravindra, et al. “Liver transplantation in an adolescent with acute liver failure from acute lymphoblastic leukemia.Pediatr Transplant 18, no. 2 (March 2014): E57–63. https://doi.org/10.1111/petr.12221.
Reddi DM, Barbas AS, Castleberry AW, Rege AS, Vikraman DS, Brennan TV, et al. Liver transplantation in an adolescent with acute liver failure from acute lymphoblastic leukemia. Pediatr Transplant. 2014 Mar;18(2):E57–63.
Reddi, D. M., et al. “Liver transplantation in an adolescent with acute liver failure from acute lymphoblastic leukemia.Pediatr Transplant, vol. 18, no. 2, Mar. 2014, pp. E57–63. Pubmed, doi:10.1111/petr.12221.
Reddi DM, Barbas AS, Castleberry AW, Rege AS, Vikraman DS, Brennan TV, Ravindra KV, Collins BH, Sudan DL, Lagoo AS, Martin AE. Liver transplantation in an adolescent with acute liver failure from acute lymphoblastic leukemia. Pediatr Transplant. 2014 Mar;18(2):E57–E63.
Journal cover image

Published In

Pediatr Transplant

DOI

EISSN

1399-3046

Publication Date

March 2014

Volume

18

Issue

2

Start / End Page

E57 / E63

Location

Denmark

Related Subject Headings

  • Treatment Outcome
  • Tissue Donors
  • Surgery
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma
  • Male
  • Liver Transplantation
  • Liver Function Tests
  • Liver Failure, Acute
  • Liver
  • Leukemia, B-Cell