Valvular heart disease in patients supported with left ventricular assist devices.
Patients with advanced HF and coexisting VHD who undergo LVAD implantation constitute a growing population and pose unique challenges in clinical and surgical management. Contemporary continuous-flow LVADs alter blood flow dynamics and cardiovascular physiology and can induce progression of preexisting VHD or lead to de novo VHD. Although we have defined our recommendations for treatment options (Table 2), continued changes to device technology, patient selection, and surgical techniques will undoubtedly lead to further changes in practice. Finally, the rapid growth in the field of mechanical circulatory support necessitates collaborative multicenter approaches to study the impact of these practice changes in the form of prospective randomized trials.
Duke Scholars
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Related Subject Headings
- Ventricular Dysfunction, Left
- Tricuspid Valve
- Treatment Outcome
- Mitral Valve
- Humans
- Hemodynamics
- Heart-Assist Devices
- Heart Valve Diseases
- Disease Management
- Cardiovascular System & Hematology
Citation
Published In
DOI
EISSN
Publication Date
Volume
Issue
Start / End Page
Location
Related Subject Headings
- Ventricular Dysfunction, Left
- Tricuspid Valve
- Treatment Outcome
- Mitral Valve
- Humans
- Hemodynamics
- Heart-Assist Devices
- Heart Valve Diseases
- Disease Management
- Cardiovascular System & Hematology