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Inhibition of the cardiomyocyte-specific troponin I-interacting kinase limits oxidative stress, injury, and adverse remodeling due to ischemic heart disease.

Publication ,  Journal Article
Abraham, DM; Marchuk, DA
Published in: Circ Res
March 14, 2014

Ischemia–reperfusion injury is strongly associated with increased oxidative stress, mitochondrial dysfunction, and cell death. These processes are diminished in an animal model of ischemia–reperfusion by the genetic loss or pharmacological inhibition of troponin I–interacting kinase.

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Published In

Circ Res

DOI

EISSN

1524-4571

Publication Date

March 14, 2014

Volume

114

Issue

6

Start / End Page

938 / 940

Location

United States

Related Subject Headings

  • Ventricular Remodeling
  • Protein Kinases
  • Oxidative Stress
  • Myocardial Ischemia
  • MAP Kinase Kinase Kinases
  • Humans
  • Cardiovascular System & Hematology
  • Animals
  • 3202 Clinical sciences
  • 3201 Cardiovascular medicine and haematology
 

Citation

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Abraham, D. M., & Marchuk, D. A. (2014). Inhibition of the cardiomyocyte-specific troponin I-interacting kinase limits oxidative stress, injury, and adverse remodeling due to ischemic heart disease. Circ Res, 114(6), 938–940. https://doi.org/10.1161/CIRCRESAHA.113.303238
Abraham, Dennis M., and Douglas A. Marchuk. “Inhibition of the cardiomyocyte-specific troponin I-interacting kinase limits oxidative stress, injury, and adverse remodeling due to ischemic heart disease.Circ Res 114, no. 6 (March 14, 2014): 938–40. https://doi.org/10.1161/CIRCRESAHA.113.303238.
Abraham, Dennis M., and Douglas A. Marchuk. “Inhibition of the cardiomyocyte-specific troponin I-interacting kinase limits oxidative stress, injury, and adverse remodeling due to ischemic heart disease.Circ Res, vol. 114, no. 6, Mar. 2014, pp. 938–40. Pubmed, doi:10.1161/CIRCRESAHA.113.303238.

Published In

Circ Res

DOI

EISSN

1524-4571

Publication Date

March 14, 2014

Volume

114

Issue

6

Start / End Page

938 / 940

Location

United States

Related Subject Headings

  • Ventricular Remodeling
  • Protein Kinases
  • Oxidative Stress
  • Myocardial Ischemia
  • MAP Kinase Kinase Kinases
  • Humans
  • Cardiovascular System & Hematology
  • Animals
  • 3202 Clinical sciences
  • 3201 Cardiovascular medicine and haematology