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Inflammation and Coagulation as Mediators in the Relationships Between Religious Attendance and Functional Limitations in Older Adults.

Publication ,  Journal Article
Hybels, CF; George, LK; Blazer, DG; Pieper, CF; Cohen, HJ; Koenig, HG
Published in: J Aging Health
June 2014

OBJECTIVE: The aim of this study was to examine inflammation and coagulation, which are positively linked to disability and inversely linked to increased religious attendance, as mediators in the cross-sectional relationships between religious attendance and functional status. METHOD: Frequency of attendance and limitations in basic activities of daily living (ADLs), instrumental activities (IADLs), and mobility were assessed in 1,423 elders. RESULTS: More frequent attendance was associated with fewer ADL, IADL, and mobility limitations, and with lower levels of inflammation and coagulation including interleukin-6, soluble vascular cell adhesion molecule, and D-dimer. Inflammation and coagulation partially mediated the associations between attendance and function. Eight percent of the effect of attendance on ADL (p = .014), 5% of the effect on IADL (p = .003), and 8% of the effect on mobility (p = .001) limitations were due to inflammation and coagulation. DISCUSSION: Relationships between attendance and function may be due in part to lower levels of inflammation and coagulation among elders who attend services.

Duke Scholars

Published In

J Aging Health

DOI

EISSN

1552-6887

Publication Date

June 2014

Volume

26

Issue

4

Start / End Page

679 / 697

Location

United States

Related Subject Headings

  • Gerontology
  • 4206 Public health
  • 3202 Clinical sciences
  • 1117 Public Health and Health Services
 

Citation

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MLA
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Hybels, C. F., George, L. K., Blazer, D. G., Pieper, C. F., Cohen, H. J., & Koenig, H. G. (2014). Inflammation and Coagulation as Mediators in the Relationships Between Religious Attendance and Functional Limitations in Older Adults. J Aging Health, 26(4), 679–697. https://doi.org/10.1177/0898264314527479
Hybels, Celia F., Linda K. George, Dan G. Blazer, Carl F. Pieper, Harvey J. Cohen, and Harold G. Koenig. “Inflammation and Coagulation as Mediators in the Relationships Between Religious Attendance and Functional Limitations in Older Adults.J Aging Health 26, no. 4 (June 2014): 679–97. https://doi.org/10.1177/0898264314527479.
Hybels CF, George LK, Blazer DG, Pieper CF, Cohen HJ, Koenig HG. Inflammation and Coagulation as Mediators in the Relationships Between Religious Attendance and Functional Limitations in Older Adults. J Aging Health. 2014 Jun;26(4):679–97.
Hybels, Celia F., et al. “Inflammation and Coagulation as Mediators in the Relationships Between Religious Attendance and Functional Limitations in Older Adults.J Aging Health, vol. 26, no. 4, June 2014, pp. 679–97. Pubmed, doi:10.1177/0898264314527479.
Hybels CF, George LK, Blazer DG, Pieper CF, Cohen HJ, Koenig HG. Inflammation and Coagulation as Mediators in the Relationships Between Religious Attendance and Functional Limitations in Older Adults. J Aging Health. 2014 Jun;26(4):679–697.
Journal cover image

Published In

J Aging Health

DOI

EISSN

1552-6887

Publication Date

June 2014

Volume

26

Issue

4

Start / End Page

679 / 697

Location

United States

Related Subject Headings

  • Gerontology
  • 4206 Public health
  • 3202 Clinical sciences
  • 1117 Public Health and Health Services