Overview
Analytic Interests.
1) Issues in the Design of Medical Experiments: I explore the use of reliability/generalizability models in experimental design. In addition to incorporation of reliability, I study powering longitudinal trials with multiple outcomes and substantial missing data using Mixed models.
2) Issues in the Analysis of Repeated Measures Designs & Longitudinal Data: Use of Hierarchical Linear Models (HLM) or Mixed Models in modeling trajectories of multiple variables over time (e.g., physical and cognitive functioning and Blood Pressure). My current work involves methodologies in simultaneous estimation of trajectories for multiple variables within and between domains, modeling co-occuring change.
Areas of Substantive interest: (1) Experimental design and analysis in gerontology and geriatrics, and psychiatry,
(2) Multivariate repeated measures designs,
1) Issues in the Design of Medical Experiments: I explore the use of reliability/generalizability models in experimental design. In addition to incorporation of reliability, I study powering longitudinal trials with multiple outcomes and substantial missing data using Mixed models.
2) Issues in the Analysis of Repeated Measures Designs & Longitudinal Data: Use of Hierarchical Linear Models (HLM) or Mixed Models in modeling trajectories of multiple variables over time (e.g., physical and cognitive functioning and Blood Pressure). My current work involves methodologies in simultaneous estimation of trajectories for multiple variables within and between domains, modeling co-occuring change.
Areas of Substantive interest: (1) Experimental design and analysis in gerontology and geriatrics, and psychiatry,
(2) Multivariate repeated measures designs,
Current Appointments & Affiliations
Professor of Biostatistics & Bioinformatics
·
2022 - Present
Biostatistics & Bioinformatics, Division of Biostatistics,
Biostatistics & Bioinformatics
Recent Publications
Association of Coprescribing of Gabapentinoid and Other Psychoactive Medications With Altered Mental Status and Falls in Adults Receiving Dialysis.
Journal Article Am J Kidney Dis · February 2025 RATIONALE & OBJECTIVE: Prescribing psychoactive medications for patients with kidney disease is common, but for patients receiving dialysis some medications may be inappropriate. We evaluated the association of coprescribing gabapentinoids and other psycho ... Full text Link to item CiteEffect of donepezil on bone metabolism among older adults with Alzheimer's disease.
Journal Article Contemp Clin Trials · January 2025 Older adults with Alzheimer's disease (AD), in addition to significant cognitive disability, have twice the risk of fracture compared to those with normal cognition. Fractures among older adults with AD are associated with substantial morbidity, loss of ph ... Full text Link to item CiteDevelopment of a physical performance summary score in middle age: Findings from the CARDIA Function study.
Conference Am J Epidemiol · December 23, 2024 Few physical performance batteries exist that appropriately evaluate physical limitations in middle-aged adults. We aimed to develop a physical performance summary score that is appropriate for use in epidemiology studies of middle-aged adults using data f ... Full text Link to item CiteRecent Grants
Measuring Racial Equity and Institutional Racism in Primary Care (EQUIP)
ResearchCo Investigator · Awarded by National Institutes of Health · 2024 - 2028Sickle Cell Disease Functional Assessment Validation and Exercise Pilot Intervention
ResearchAdvisor · Awarded by National Heart, Lung, and Blood Institute · 2023 - 2028Legacy Effects of CALERIE, a 2-year Calorie Restriction Intervention, on Hallmarks of Healthspan and Aging
ResearchCo Investigator · Awarded by Tufts Medical Center · 2022 - 2026View All Grants
Education, Training & Certifications
Columbia University ·
1990
DrPH