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True color scanning laser ophthalmoscopy and optical coherence tomography handheld probe.

Publication ,  Journal Article
LaRocca, F; Nankivil, D; Farsiu, S; Izatt, JA
Published in: Biomedical optics express
September 2014

Scanning laser ophthalmoscopes (SLOs) are able to achieve superior contrast and axial sectioning capability compared to fundus photography. However, SLOs typically use monochromatic illumination and are thus unable to extract color information of the retina. Previous color SLO imaging techniques utilized multiple lasers or narrow band sources for illumination, which allowed for multiple color but not "true color" imaging as done in fundus photography. We describe the first "true color" SLO, handheld color SLO, and combined color SLO integrated with a spectral domain optical coherence tomography (OCT) system. To achieve accurate color imaging, the SLO was calibrated with a color test target and utilized an achromatizing lens when imaging the retina to correct for the eye's longitudinal chromatic aberration. Color SLO and OCT images from volunteers were then acquired simultaneously with a combined power under the ANSI limit. Images from this system were then compared with those from commercially available SLOs featuring multiple narrow-band color imaging.

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Published In

Biomedical optics express

DOI

EISSN

2156-7085

ISSN

2156-7085

Publication Date

September 2014

Volume

5

Issue

9

Start / End Page

3204 / 3216

Related Subject Headings

  • 5102 Atomic, molecular and optical physics
  • 4003 Biomedical engineering
  • 3212 Ophthalmology and optometry
  • 0912 Materials Engineering
  • 0205 Optical Physics
 

Citation

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LaRocca, F., Nankivil, D., Farsiu, S., & Izatt, J. A. (2014). True color scanning laser ophthalmoscopy and optical coherence tomography handheld probe. Biomedical Optics Express, 5(9), 3204–3216. https://doi.org/10.1364/boe.5.003204
LaRocca, Francesco, Derek Nankivil, Sina Farsiu, and Joseph A. Izatt. “True color scanning laser ophthalmoscopy and optical coherence tomography handheld probe.Biomedical Optics Express 5, no. 9 (September 2014): 3204–16. https://doi.org/10.1364/boe.5.003204.
LaRocca F, Nankivil D, Farsiu S, Izatt JA. True color scanning laser ophthalmoscopy and optical coherence tomography handheld probe. Biomedical optics express. 2014 Sep;5(9):3204–16.
LaRocca, Francesco, et al. “True color scanning laser ophthalmoscopy and optical coherence tomography handheld probe.Biomedical Optics Express, vol. 5, no. 9, Sept. 2014, pp. 3204–16. Epmc, doi:10.1364/boe.5.003204.
LaRocca F, Nankivil D, Farsiu S, Izatt JA. True color scanning laser ophthalmoscopy and optical coherence tomography handheld probe. Biomedical optics express. 2014 Sep;5(9):3204–3216.
Journal cover image

Published In

Biomedical optics express

DOI

EISSN

2156-7085

ISSN

2156-7085

Publication Date

September 2014

Volume

5

Issue

9

Start / End Page

3204 / 3216

Related Subject Headings

  • 5102 Atomic, molecular and optical physics
  • 4003 Biomedical engineering
  • 3212 Ophthalmology and optometry
  • 0912 Materials Engineering
  • 0205 Optical Physics