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Importance of neutralization sieve analyses when seeking correlates of HIV-1 vaccine efficacy.

Publication ,  Other
Montefiori, DC
Published in: Hum Vaccin Immunother
2014

This commentary describes a rationale for the use of breakthrough viruses from clinical trial participants to assess neutralizing antibodies as a correlate of HIV-1 vaccine efficacy. The rationale is based on principles of a genetic sieve analysis, where the 2 analyses may be cooperative for delineating neutralizing antibodies as a mechanistic correlate of protection.

Duke Scholars

Published In

Hum Vaccin Immunother

DOI

EISSN

2164-554X

Publication Date

2014

Volume

10

Issue

8

Start / End Page

2507 / 2511

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Humans
  • HIV Antibodies
  • Biomedical Research
  • Biomarkers
  • Antibodies, Neutralizing
  • Acquired Immunodeficiency Syndrome
  • AIDS Vaccines
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Montefiori, D. C. (2014). Importance of neutralization sieve analyses when seeking correlates of HIV-1 vaccine efficacy. Hum Vaccin Immunother. United States. https://doi.org/10.4161/hv.28950
Montefiori, David C. “Importance of neutralization sieve analyses when seeking correlates of HIV-1 vaccine efficacy.Hum Vaccin Immunother, 2014. https://doi.org/10.4161/hv.28950.
Montefiori DC. Importance of neutralization sieve analyses when seeking correlates of HIV-1 vaccine efficacy. Vol. 10, Hum Vaccin Immunother. 2014. p. 2507–11.
Montefiori, David C. “Importance of neutralization sieve analyses when seeking correlates of HIV-1 vaccine efficacy.Hum Vaccin Immunother, vol. 10, no. 8, 2014, pp. 2507–11. Pubmed, doi:10.4161/hv.28950.

Published In

Hum Vaccin Immunother

DOI

EISSN

2164-554X

Publication Date

2014

Volume

10

Issue

8

Start / End Page

2507 / 2511

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Humans
  • HIV Antibodies
  • Biomedical Research
  • Biomarkers
  • Antibodies, Neutralizing
  • Acquired Immunodeficiency Syndrome
  • AIDS Vaccines