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The potential role of natriuretic peptide-guided management for patients hospitalized for heart failure.

Publication ,  Journal Article
Maisel, A; Xue, Y; Greene, SJ; Pang, PS; Januzzi, JL; Piña, IL; DeFilippi, C; Butler, J
Published in: J Card Fail
March 2015

There are >1 million hospitalizations for heart failure (HF) in the United States annually. After discharge, 25% of these patients are rehospitalized within 30 days, and 30% are dead within 1 year. To date, all trials in patients with acute HF (AHF) have failed to improve post-discharge outcomes. There remains a need for an effective objective risk stratification strategy that is capable of reliably identifying patients at heightened risk for readmission and informing discharge decision making. Natriuretic peptide (NP) levels during and after AHF hospitalization can provide valuable information regarding congestion status and chronic remodeling stress. The lack of sensitivity and inter-rater reliability of physical examination, and failure to achieve dry weight in many patients before discharge, renders the use of NP to guide therapy to prevent readmission an attractive option. NP levels can be used across the spectrum of AHF care settings, ranging from the emergency department and inpatient stay to post-discharge follow-up and chronic management. This review summarizes available data and provides an expert opinion on the potential role of NPs to reduce HF readmissions.

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Published In

J Card Fail

DOI

EISSN

1532-8414

Publication Date

March 2015

Volume

21

Issue

3

Start / End Page

233 / 239

Location

United States

Related Subject Headings

  • Natriuretic Peptides
  • Humans
  • Hospitalization
  • Heart Failure
  • Disease Management
  • Cardiovascular System & Hematology
  • Biomarkers
  • 3202 Clinical sciences
  • 3201 Cardiovascular medicine and haematology
  • 1110 Nursing
 

Citation

APA
Chicago
ICMJE
MLA
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Maisel, A., Xue, Y., Greene, S. J., Pang, P. S., Januzzi, J. L., Piña, I. L., … Butler, J. (2015). The potential role of natriuretic peptide-guided management for patients hospitalized for heart failure. J Card Fail, 21(3), 233–239. https://doi.org/10.1016/j.cardfail.2014.11.009
Maisel, Alan, Yang Xue, Stephen J. Greene, Peter S. Pang, James L. Januzzi, Ileana L. Piña, Christopher DeFilippi, and Javed Butler. “The potential role of natriuretic peptide-guided management for patients hospitalized for heart failure.J Card Fail 21, no. 3 (March 2015): 233–39. https://doi.org/10.1016/j.cardfail.2014.11.009.
Maisel A, Xue Y, Greene SJ, Pang PS, Januzzi JL, Piña IL, et al. The potential role of natriuretic peptide-guided management for patients hospitalized for heart failure. J Card Fail. 2015 Mar;21(3):233–9.
Maisel, Alan, et al. “The potential role of natriuretic peptide-guided management for patients hospitalized for heart failure.J Card Fail, vol. 21, no. 3, Mar. 2015, pp. 233–39. Pubmed, doi:10.1016/j.cardfail.2014.11.009.
Maisel A, Xue Y, Greene SJ, Pang PS, Januzzi JL, Piña IL, DeFilippi C, Butler J. The potential role of natriuretic peptide-guided management for patients hospitalized for heart failure. J Card Fail. 2015 Mar;21(3):233–239.
Journal cover image

Published In

J Card Fail

DOI

EISSN

1532-8414

Publication Date

March 2015

Volume

21

Issue

3

Start / End Page

233 / 239

Location

United States

Related Subject Headings

  • Natriuretic Peptides
  • Humans
  • Hospitalization
  • Heart Failure
  • Disease Management
  • Cardiovascular System & Hematology
  • Biomarkers
  • 3202 Clinical sciences
  • 3201 Cardiovascular medicine and haematology
  • 1110 Nursing