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Human Cardiac Tissue Engineering: From Pluripotent Stem Cells to Heart Repair.

Publication ,  Journal Article
Jackman, CP; Shadrin, IY; Carlson, AL; Bursac, N
Published in: Current opinion in chemical engineering
February 2015

Engineered cardiac tissues hold great promise for use in drug and toxicology screening, in vitro studies of human physiology and disease, and as transplantable tissue grafts for myocardial repair. In this review, we discuss recent progress in cell-based therapy and functional tissue engineering using pluripotent stem cell-derived cardiomyocytes and we describe methods for delivery of cells into the injured heart. While significant hurdles remain, notable advances have been made in the methods to derive large numbers of pure human cardiomyocytes, mature their phenotype, and produce and implant functional cardiac tissues, bringing the field a step closer to widespread in vitro and in vivo applications.

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Published In

Current opinion in chemical engineering

DOI

EISSN

2211-3398

ISSN

2211-3398

Publication Date

February 2015

Volume

7

Start / End Page

57 / 64

Related Subject Headings

  • 4004 Chemical engineering
  • 0904 Chemical Engineering
 

Citation

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ICMJE
MLA
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Jackman, C. P., Shadrin, I. Y., Carlson, A. L., & Bursac, N. (2015). Human Cardiac Tissue Engineering: From Pluripotent Stem Cells to Heart Repair. Current Opinion in Chemical Engineering, 7, 57–64. https://doi.org/10.1016/j.coche.2014.11.004
Jackman, Christopher P., Ilya Y. Shadrin, Aaron L. Carlson, and Nenad Bursac. “Human Cardiac Tissue Engineering: From Pluripotent Stem Cells to Heart Repair.Current Opinion in Chemical Engineering 7 (February 2015): 57–64. https://doi.org/10.1016/j.coche.2014.11.004.
Jackman CP, Shadrin IY, Carlson AL, Bursac N. Human Cardiac Tissue Engineering: From Pluripotent Stem Cells to Heart Repair. Current opinion in chemical engineering. 2015 Feb;7:57–64.
Jackman, Christopher P., et al. “Human Cardiac Tissue Engineering: From Pluripotent Stem Cells to Heart Repair.Current Opinion in Chemical Engineering, vol. 7, Feb. 2015, pp. 57–64. Epmc, doi:10.1016/j.coche.2014.11.004.
Jackman CP, Shadrin IY, Carlson AL, Bursac N. Human Cardiac Tissue Engineering: From Pluripotent Stem Cells to Heart Repair. Current opinion in chemical engineering. 2015 Feb;7:57–64.
Journal cover image

Published In

Current opinion in chemical engineering

DOI

EISSN

2211-3398

ISSN

2211-3398

Publication Date

February 2015

Volume

7

Start / End Page

57 / 64

Related Subject Headings

  • 4004 Chemical engineering
  • 0904 Chemical Engineering