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Effects of elevated nitrate on endocrine function in Atlantic salmon, Salmo salar

Publication ,  Journal Article
Freitag, AR; Thayer, LAR; Leonetti, C; Stapleton, HM; Hamlin, HJ
Published in: Aquaculture
January 1, 2015

Recirculating aquaculture systems (RAS) have recently emerged as a sustainable alternative to traditional net pen or flow-through aquaculture. These systems reduce the environmental impact of fish production by treating and recycling culture water, and could be used in the large-scale commercial production of a variety of fish species including Atlantic salmon (Salmo salar). One major concern surrounding RAS is the natural accumulation of nitrate in the culture water. An experiment was conducted to investigate the sublethal effects of elevated nitrate on juvenile Atlantic salmon, with emphasis on thyroidal and steroidogenic endpoints. Animals were exposed to 5.2, 10.3 or 101.8. mg/L nitrate-N for 27. days. Upon completion of the trial, the animals were euthanized and bled by puncture of the caudal vein. Mean plasma nitrate/nitrite concentrations increased significantly with increasing ambient nitrate-N concentration. Plasma testosterone concentrations displayed a highly significant non-monotonic dose response to increasing nitrate-N concentration, and were elevated at 10.3. mg/L nitrate-N. Plasma 11-ketotestosterone, total thyroxine and total triiodothyronine concentrations did not differ significantly between treatments. These results suggest that elevated nitrate can interfere with the synthesis or metabolism of sex steroids, but that Atlantic salmon may be relatively insensitive, in terms of growth and most endocrine endpoints examined, to nitrate-N concentrations up to 101.8. mg/L, and are a promising candidate for production in RAS.

Duke Scholars

Published In

Aquaculture

DOI

ISSN

0044-8486

Publication Date

January 1, 2015

Volume

436

Start / End Page

8 / 12

Related Subject Headings

  • Fisheries
  • 3109 Zoology
  • 3009 Veterinary sciences
  • 3005 Fisheries sciences
  • 0704 Fisheries Sciences
  • 0608 Zoology
 

Citation

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Freitag, A. R., Thayer, L. A. R., Leonetti, C., Stapleton, H. M., & Hamlin, H. J. (2015). Effects of elevated nitrate on endocrine function in Atlantic salmon, Salmo salar. Aquaculture, 436, 8–12. https://doi.org/10.1016/j.aquaculture.2014.10.041
Freitag, A. R., L. A. R. Thayer, C. Leonetti, H. M. Stapleton, and H. J. Hamlin. “Effects of elevated nitrate on endocrine function in Atlantic salmon, Salmo salar.” Aquaculture 436 (January 1, 2015): 8–12. https://doi.org/10.1016/j.aquaculture.2014.10.041.
Freitag AR, Thayer LAR, Leonetti C, Stapleton HM, Hamlin HJ. Effects of elevated nitrate on endocrine function in Atlantic salmon, Salmo salar. Aquaculture. 2015 Jan 1;436:8–12.
Freitag, A. R., et al. “Effects of elevated nitrate on endocrine function in Atlantic salmon, Salmo salar.” Aquaculture, vol. 436, Jan. 2015, pp. 8–12. Scopus, doi:10.1016/j.aquaculture.2014.10.041.
Freitag AR, Thayer LAR, Leonetti C, Stapleton HM, Hamlin HJ. Effects of elevated nitrate on endocrine function in Atlantic salmon, Salmo salar. Aquaculture. 2015 Jan 1;436:8–12.
Journal cover image

Published In

Aquaculture

DOI

ISSN

0044-8486

Publication Date

January 1, 2015

Volume

436

Start / End Page

8 / 12

Related Subject Headings

  • Fisheries
  • 3109 Zoology
  • 3009 Veterinary sciences
  • 3005 Fisheries sciences
  • 0704 Fisheries Sciences
  • 0608 Zoology