Skip to main content
release_alert
Welcome to the new Scholars 3.0! Read about new features and let us know what you think.
cancel
Journal cover image

Donation after cardiac death: the university of wisconsin experience with renal transplantation.

Publication ,  Journal Article
Cooper, JT; Chin, LT; Krieger, NR; Fernandez, LA; Foley, DP; Becker, YT; Odorico, JS; Knechtle, SJ; Kalayoglu, M; Sollinger, HW; D'Alessandro, AM
Published in: Am J Transplant
September 2004

Owing to the shortage of organ donors, there is renewed interest in donation after cardiac death (DCD), formerly referred to as nonheart-beating donation. From January 1984 until August 2000, 382 renal transplants were performed from DCD donors. These were compared with 1089 renal transplants performed from donation after brain death (DBD) donors. The mean warm ischemic time in DCD donors was 16.5 min. There was no statistical difference in cold ischemic time, rate of primary nonfunction, or graft loss in the first 30 days after transplantation. The rate of delayed graft function (DGF) was higher for DCD donors (27.5% vs. 21.3%; p = 0.016) and discharge creatinine was higher in DCD donors (1.92 mg/dL vs. 1.71 mg/dL; p = 0.001). There was no statistical difference in the 5-, 10-, or 15-year allograft survival when DCD donors were compared with DBD donors (64.8%, 44.8%, 27.8% vs. 71.3%, 48.3%, 33.8%; p = 0.054). Likewise, no statistical difference in the rate of technical complications was seen. Our long-term data indicate that the results of renal transplantation from DCD donors are equivalent to long-term allograft survival from DBD donors despite an increase in the rate of DGF. Organ procurement organizations, transplant centers, and hospitals should work to expand the implementation of DCD policies.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

Am J Transplant

DOI

ISSN

1600-6135

Publication Date

September 2004

Volume

4

Issue

9

Start / End Page

1490 / 1494

Location

United States

Related Subject Headings

  • Wisconsin
  • Tissue and Organ Harvesting
  • Tissue Preservation
  • Tissue Donors
  • Time Factors
  • Survivors
  • Surgery
  • Retrospective Studies
  • Nephrectomy
  • Kidney Transplantation
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Cooper, J. T., Chin, L. T., Krieger, N. R., Fernandez, L. A., Foley, D. P., Becker, Y. T., … D’Alessandro, A. M. (2004). Donation after cardiac death: the university of wisconsin experience with renal transplantation. Am J Transplant, 4(9), 1490–1494. https://doi.org/10.1111/j.1600-6143.2004.00531.x
Cooper, Jeffrey T., L Thomas Chin, Nancy R. Krieger, Luis A. Fernandez, David P. Foley, Yolanda T. Becker, Jon S. Odorico, et al. “Donation after cardiac death: the university of wisconsin experience with renal transplantation.Am J Transplant 4, no. 9 (September 2004): 1490–94. https://doi.org/10.1111/j.1600-6143.2004.00531.x.
Cooper JT, Chin LT, Krieger NR, Fernandez LA, Foley DP, Becker YT, et al. Donation after cardiac death: the university of wisconsin experience with renal transplantation. Am J Transplant. 2004 Sep;4(9):1490–4.
Cooper, Jeffrey T., et al. “Donation after cardiac death: the university of wisconsin experience with renal transplantation.Am J Transplant, vol. 4, no. 9, Sept. 2004, pp. 1490–94. Pubmed, doi:10.1111/j.1600-6143.2004.00531.x.
Cooper JT, Chin LT, Krieger NR, Fernandez LA, Foley DP, Becker YT, Odorico JS, Knechtle SJ, Kalayoglu M, Sollinger HW, D’Alessandro AM. Donation after cardiac death: the university of wisconsin experience with renal transplantation. Am J Transplant. 2004 Sep;4(9):1490–1494.
Journal cover image

Published In

Am J Transplant

DOI

ISSN

1600-6135

Publication Date

September 2004

Volume

4

Issue

9

Start / End Page

1490 / 1494

Location

United States

Related Subject Headings

  • Wisconsin
  • Tissue and Organ Harvesting
  • Tissue Preservation
  • Tissue Donors
  • Time Factors
  • Survivors
  • Surgery
  • Retrospective Studies
  • Nephrectomy
  • Kidney Transplantation