Stuart Johnston Knechtle

Stuart Johnston Knechtle
William R. Kenan, Jr. Distinguished Professor

During my career as an academic surgeon, I have had the privilege of leading and/or participating in a diverse portfolio of hypothesis-driven research projects. These projects have centered on the immunology of surgery and transplantation, including both cellular and antibody-mediated immune responses. During my training I studied the response of hyper-sensitized recipients to allogeneic liver transplantation, and am currently studying means of reducing immunologic memory that might allow more successful transplantation in sensitized recipients. This immune response involves pathways of coagulation, antibody-mediated rejection, and cellular rejection and current work in my lab involves these three pathways. The other major focuses of my work have been co-stimulation blockade and immune cell depletion as approaches to immunologic unresponsiveness or tolerance. My research group has been involved in translational and clinical research to develop these mechanistic tools for the benefit of human organ transplant recipients.

Recent Publications

Knechtle SJ, Shaw JM, Hering BJ, Kraemer K, Madsen JC. Translational impact of NIH-funded nonhuman primate research in transplantation. Sci Transl Med. 2019 Jul 10;11(500). pii: eaau0143. Reprint | Full Text

Current Appointments & Affiliations

William R. Kenan, Jr. Distinguished Professor, Surgery, Abdominal Transplant Surgery, Surgery 2018
Professor of Surgery, Surgery, Abdominal Transplant Surgery, Surgery 2015
Adjunct Professor in the Department of Medicine, Medicine, Nephrology, Medicine 2019
Member in the Duke Clinical Research Institute, Duke Clinical Research Institute, Institutes and Centers 2016

Contact Information

stuart.knechtle@duke.edu

Background
Education, Training, & Certifications
- Transplant Fellow, Surgery, University of Wisconsin - Madison 1989 - 1991
- Residency, Surgery, Duke University School of Medicine 1982 - 1989
- M.D., Cornell University, Weill Medical College 1982
Duke Appointment History
- Instructor, Temporary in the Department of Surgery, Surgery, Abdominal Transplant Surgery, Surgery 2015
Recognition
In the News
- MAY 5, 2016
  
  Duke Awards Distinguished Professorships, Inducts New Bass Society Members
Expertise
Subject Headings
Global Scholarship
- Research
  - United States of America (Country)
Research
Selected Grants
- Allo Vir ALVR105 awarded by Allovir, Inc. 2021 - 2026
- IMAGINE awarded by CSL Behring LLC 2020 - 2026
- Targeting mitochondrial dysfunction and damage-associated molecular patterns to improve the function of high risk grafts in liver transplantation awarded by National Institutes of Health 2020 - 2025
- IM101-823 - Abatacept for treatment of recurrent or de novo autoimmune hepatitis awarded by The Bristol-Myers/Sanofi Pharmaceuticals, Inc. Partnership 2019 - 2024
- EVALUATION OF PATIENT OUTCOMES FROM THE KIDNEY ALLOGRAFT OUTCOMES ALLOSURE REGISTRY (KOAR) AGREEMENT awarded by CareDx, Inc. 2018 - 2023
- Targeting complement C3 to prevent acute antibody-mediated rejection for a deceased-donor kidney transplant in sensitized recipients awarded by Alexion Pharmaceuticals, Inc. 2021 - 2023
- Developing clinically relevant immunosuppressive regimen for pig to rhesus kidney transplantation using transgenic pigs awarded by eGenesis, Inc. 2021 - 2023
- Duke CTSA (TL1) awarded by National Institutes of Health 2018 - 2023
- Novel development ofan acoustofluidic device for targeted antibody removal in pediatric organ transplan rejection awarded by National Institutes of Health 2021 - 2023
- LET vs VGCV for Prevention of CMV disease in Kidney Transplant Recipients awarded by Merck Sharp & Dohme 2017 - 2023
- Duke Resident Physician-Scientist Program - NIAID awarded by National Institutes of Health 2018 - 2022
- The Risks and Opporunities of Homeostatic Repopulation awarded by National Institutes of Health 2017 - 2022
- Duke Resident Physician-Scientist Program- NHLBI awarded by National Institutes of Health 2018 - 2022
- Acoustic Device to Prevent Antibody Mediated Organ Transplant Failure awarded by Hartwell Foundation 2019 - 2022
- Measuring the Impact of Allosensitization on Xenotransplantation awarded by National Institutes of Health 2020 - 2022
- ITN336 Immune Tolerance Network awarded by Benaroya Research Institute at Virginia Mason 2019 - 2022
- Alexion Sponsored Research Agreement awarded by Alexion Pharmaceuticals, Inc. 2020 - 2021
- Acoustic based plasmapheresis to prevent antibody-mediated organ transplant awarded by The Board of Regents of the University of Wisconsin System 2019 - 2021
- Lung Transplant Plasmapheresis (PLEX)/Belatacept/Carfilzomib Protocol for Treatment of Antibody Mediated Rejection (AMR) and Desensitization awarded by Bristol-Myers Squibb Company 2019 - 2020
- ASTS Presidential Student Mentor Grant awarded by American Society of Transplant Surgeons 2019
- Transplant Tolerance in Non-Human Primates awarded by Emory University 2015 - 2017
- Preventing allograft rejection but not tolerance by blockade of the lymphocyte store-operated calcium channel awarded by Department of Defense 2016 - 2017
- Visiting Research Fellowship awarded by King's College London 2015 - 2016
- Prevention of Homograft Induced Cardiac Allograft Vasculopathy in Pediatric Heart Transplantation awarded by Enduring Hearts 2015 - 2016
- Preventing allograft rejection but not tolerance by blockade of the lymphocyte store-operated calcium channel awarded by Synta Pharmaceuticals Corp. 2015 - 2016
- Inducible Regulatory B Cells in Transplantation Tolerance awarded by University of Wisconsin 2015 - 2016
External Relationships
- Renovar
Publications & Artistic Works
Selected Publications
- Books
  - Knechtle, S. J., L. P. Marson, and P. J. Morris. Preface to the eighth edition, 2019. https://doi.org/10.1016/B978-0-323-53186-3.05002-6.
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  - Knechtle, S. J., L. P. Marson, and P. J. Morris. Kidney transplantation - Principles and practice, 2019. https://doi.org/10.1016/C2016-0-01606-6.
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  - Morris, P. J., and S. J. Knechtle. Preface to the Sixth Edition, 2008. https://doi.org/10.1016/B978-1-4160-3343-1.50004-9.
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  - Morris, P. J., and S. J. Knechtle. Kidney Transplantation, 2008.
  - Morris, P. J., and S. J. Knechtle. Kidney Transplantation, 2008. https://doi.org/10.1016/B978-1-4160-3343-1.X5001-4.
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- Academic Articles
  - Halpern, Samantha E., Dimitrios Moris, Brian I. Shaw, Samuel J. Kesseli, Mariya L. Samoylova, Miriam Manook, Robin Schmitz, et al. “Definition and Analysis of Textbook Outcome: A Novel Quality Measure in Kidney Transplantation.” World J Surg 45, no. 5 (May 2021): 1504–13. https://doi.org/10.1007/s00268-020-05943-y.
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  - Knechtle, Stuart J., Danielle Niedfeldt, Debra Sudan, Annette Jackson, Ian Jamieson, Matthew Hartwig, and Carmelo Milano. “Another Step Toward Becoming a Transplant Community.” Ann Surg 273, no. 4 (April 1, 2021): e149–50. https://doi.org/10.1097/SLA.0000000000004472.
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  - Choi, Ashley Y., Miriam Manook, Danae Olaso, Brian Ezekian, Jaeberm Park, Kyle Freischlag, Annette Jackson, Stuart Knechtle, and Jean Kwun. “Emerging New Approaches in Desensitization: Targeted Therapies for HLA Sensitization.” Front Immunol 12 (2021): 694763. https://doi.org/10.3389/fimmu.2021.694763.
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  - Manook, Miriam, Walter J. Flores, Robin Schmitz, Zachary Fitch, Janghoon Yoon, Yeeun Bae, Brian Shaw, et al. “Measuring the Impact of Targeting FcRn-Mediated IgG Recycling on Donor-Specific Alloantibodies in a Sensitized NHP Model.” Front Immunol 12 (2021): 660900. https://doi.org/10.3389/fimmu.2021.660900.
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  - Schroder, Paul M., Robin Schmitz, Zachary W. Fitch, Brian Ezekian, Janghoon Yoon, Ashley Y. Choi, Miriam Manook, et al. “Preoperative carfilzomib and lulizumab based desensitization prolongs graft survival in a sensitized non-human primate model.” Kidney Int 99, no. 1 (January 2021): 161–72. https://doi.org/10.1016/j.kint.2020.08.020.
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  - Kapila, Nikhil, Ying Claire Dorsey, Jigesh Shah, Lindsay King, Kadiyala Ravindra, Stuart Knechtle, and Yuval Patel. “Transjugular Intrahepatic Portosystemic Shunt for a Challenging Pregnancy.” Am J Gastroenterol 115, no. 12 (December 2020): 1935. https://doi.org/10.14309/ajg.0000000000000602.
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  - Dangi, Anil, Shuangjin Yu, Frances T. Lee, Melanie Burnette, Stuart Knechtle, Jean Kwun, and Xunrong Luo. “Donor apoptotic cell-based therapy for effective inhibition of donor-specific memory T and B cells to promote long-term allograft survival in allosensitized recipients.” Am J Transplant 20, no. 10 (October 2020): 2728–39. https://doi.org/10.1111/ajt.15878.
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  - Kwun, Jean, and Stuart Knechtle. “Pharmacological approaches to antibody-mediated rejection-Are we getting closer?” Am J Transplant 20, no. 10 (October 2020): 2637–38. https://doi.org/10.1111/ajt.16061.
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  - Moris, Dimitrios, Brian I. Shaw, Jared Gloria, Samuel J. Kesseli, Mariya L. Samoylova, Robin Schmitz, Miriam Manook, et al. “Textbook Outcomes in Liver Transplantation.” World J Surg 44, no. 10 (October 2020): 3470–77. https://doi.org/10.1007/s00268-020-05625-9.
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  - Kesseli, Samuel J., Mariya L. Samoylova, Dimitrios Moris, Ashton A. Connor, Robin Schmitz, Brian I. Shaw, Jared N. Gloria, et al. “Outcomes in Kidney Transplantation Between Veterans Affairs and Civilian Hospitals: Considerations in the Context of the MISSION Act.” Ann Surg 272, no. 3 (September 1, 2020): 506–10. https://doi.org/10.1097/SLA.0000000000004119.
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  - Tamas, James W., Charles Y. Kim, Linnan Tang, Stuart J. Knechtle, and Paul V. Suhocki. “Percutaneous Splenorenal Shunt Creation in a Patient with Chronic Portomesenteric Thrombosis.” J Vasc Interv Radiol 31, no. 9 (September 2020): 1408–9. https://doi.org/10.1016/j.jvir.2020.04.009.
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  - Kwun, Jean, Jie Li, Clay Rouse, Jae Berm Park, Alton B. Farris, Maragatha Kuchibhatla, Joseph W. Turek, Stuart J. Knechtle, Allan D. Kirk, and M Louise Markert. “Cultured thymus tissue implantation promotes donor-specific tolerance to allogeneic heart transplants.” Jci Insight 5, no. 11 (June 4, 2020). https://doi.org/10.1172/jci.insight.129983.
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  - Knechtle, Stuart. “Antibody-Mediated Rejection.” Am J Transplant 20 Suppl 4 (June 2020): 1. https://doi.org/10.1111/ajt.16063.
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  - Kwun, Jean, and Stuart Knechtle. “Experimental modeling of desensitization: What have we learned about preventing AMR?” Am J Transplant 20 Suppl 4 (June 2020): 2–11. https://doi.org/10.1111/ajt.15873.
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  - Sawitzki, Birgit, Paul N. Harden, Petra Reinke, Aurélie Moreau, James A. Hutchinson, David S. Game, Qizhi Tang, et al. “Regulatory cell therapy in kidney transplantation (The ONE Study): a harmonised design and analysis of seven non-randomised, single-arm, phase 1/2A trials.” Lancet 395, no. 10237 (May 23, 2020): 1627–39. https://doi.org/10.1016/S0140-6736(20)30167-7.
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  - Kwun, Jean, Brian Ezekian, Miriam Manook, Jaeberm Park, Janghoon Yoon, Kyle Freischlag, Mingqing Song, et al. “Targeting Calcium Release-activated Calcium Channel Is Not Sufficient to Prevent Rejection in Nonhuman Primate Kidney Transplantation.” Transplantation 104, no. 5 (May 2020): 970–80. https://doi.org/10.1097/TP.0000000000003078.
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  - Schinstock, Carrie A., Roslyn B. Mannon, Klemens Budde, Anita S. Chong, Mark Haas, Stuart Knechtle, Carmen Lefaucheur, et al. “Recommended Treatment for Antibody-mediated Rejection After Kidney Transplantation: The 2019 Expert Consensus From the Transplantion Society Working Group.” Transplantation 104, no. 5 (May 2020): 911–22. https://doi.org/10.1097/TP.0000000000003095.
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  - Schmitz, Robin, Zachary W. Fitch, Paul M. Schroder, Ashley Y. Choi, Annette M. Jackson, Stuart J. Knechtle, and Jean Kwun. “B cells in transplant tolerance and rejection: friends or foes?” Transpl Int 33, no. 1 (January 2020): 30–40. https://doi.org/10.1111/tri.13549.
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  - VanDusen, Keith W., Sarada Eleswarpu, Eugene W. Moretti, Michael J. Devinney, Donna M. Crabtree, Daniel T. Laskowitz, Marty G. Woldorff, et al. “The MARBLE Study Protocol: Modulating ApoE Signaling to Reduce Brain Inflammation, DeLirium, and PostopErative Cognitive Dysfunction.” J Alzheimers Dis 75, no. 4 (2020): 1319–28. https://doi.org/10.3233/JAD-191185.
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  - Ezekian, Brian, Paul M. Schroder, Michael S. Mulvihill, Andrew Barbas, Bradley Collins, Kyle Freischlag, Janghoon Yoon, et al. “Pretransplant Desensitization with Costimulation Blockade and Proteasome Inhibitor Reduces DSA and Delays Antibody-Mediated Rejection in Highly Sensitized Nonhuman Primate Kidney Transplant Recipients.” J Am Soc Nephrol 30, no. 12 (December 2019): 2399–2411. https://doi.org/10.1681/ASN.2019030304.
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  - Gao, Qimeng, Michael S. Mulvihill, Uwe Scheuermann, Robert P. Davis, John Yerxa, Babatunde A. Yerokun, Matthew G. Hartwig, Debra L. Sudan, Stuart J. Knechtle, and Andrew S. Barbas. “Improvement in Liver Transplant Outcomes From Older Donors: A US National Analysis.” Ann Surg 270, no. 2 (August 2019): 333–39. https://doi.org/10.1097/SLA.0000000000002876.
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  - Schroder, Paul M., Zachary W. Fitch, Robin Schmitz, Ashley Y. Choi, Jean Kwun, and Stuart J. Knechtle. “The past, present, and future of costimulation blockade in organ transplantation.” Curr Opin Organ Transplant 24, no. 4 (August 2019): 391–401. https://doi.org/10.1097/MOT.0000000000000656.
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  - Knechtle, Stuart J., Julia M. Shaw, Bernhard J. Hering, Kristy Kraemer, and Joren C. Madsen. “Translational impact of NIH-funded nonhuman primate research in transplantation.” Sci Transl Med 11, no. 500 (July 10, 2019). https://doi.org/10.1126/scitranslmed.aau0143.
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  - Fitch, Zachary, Robin Schmitz, Jean Kwun, Bernhard Hering, Joren Madsen, and Stuart J. Knechtle. “Transplant research in nonhuman primates to evaluate clinically relevant immune strategies in organ transplantation.” Transplant Rev (Orlando) 33, no. 3 (July 2019): 115–29. https://doi.org/10.1016/j.trre.2019.03.002.
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  - Knechtle, Stuart J., and Jean Kwun. “Parallels between antibody-mediated rejection and ischemic kidney injury with respect to B cell activation.” Ann Transl Med 7, no. Suppl 3 (July 2019): S151. https://doi.org/10.21037/atm.2019.06.36.
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  - Kwun, Jean, Marie Matignon, Miriam Manook, Soulef Guendouz, Vincent Audard, David Kheav, Elsa Poullot, et al. “Daratumumab in Sensitized Kidney Transplantation: Potentials and Limitations of Experimental and Clinical Use.” J Am Soc Nephrol 30, no. 7 (July 2019): 1206–19. https://doi.org/10.1681/ASN.2018121254.
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  - Berger, Miles, Deborah Oyeyemi, Mobolaji O. Olurinde, Heather E. Whitson, Kent J. Weinhold, Marty G. Woldorff, Lewis A. Lipsitz, et al. “The INTUIT Study: Investigating Neuroinflammation Underlying Postoperative Cognitive Dysfunction.” J Am Geriatr Soc 67, no. 4 (April 2019): 794–98. https://doi.org/10.1111/jgs.15770.
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  - Burghuber, Christopher K., Miriam Manook, Brian Ezekian, Adriana C. Gibby, Frank V. Leopardi, Minqing Song, Jennifer Jenks, et al. “Dual targeting: Combining costimulation blockade and bortezomib to permit kidney transplantation in sensitized recipients.” Am J Transplant 19, no. 3 (March 2019): 724–36. https://doi.org/10.1111/ajt.15067.
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  - Knechtle, Stuart J. “Toward Long-term Livers.” Ann Surg 269, no. 1 (January 2019): 28–29. https://doi.org/10.1097/SLA.0000000000003068.
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  - Moris, Dimitrios, Ioannis D. Kostakis, Nikolaos Machairas, Anastasia Prodromidou, Diamantis I. Tsilimigras, Kadiyala V. Ravindra, Debra L. Sudan, Stuart J. Knechtle, and Andrew S. Barbas. “Comparison between liver transplantation and resection for hilar cholangiocarcinoma: A systematic review and meta-analysis.” Plos One 14, no. 7 (2019): e0220527. https://doi.org/10.1371/journal.pone.0220527.
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  - Ezekian, Brian, Michael S. Mulvihill, Paul M. Schroder, Brian F. Gilmore, Harold J. Leraas, Brian C. Gulack, Sarah Jane Commander, et al. “Improved contemporary outcomes of liver transplantation for pediatric hepatoblastoma and hepatocellular carcinoma.” Pediatr Transplant 22, no. 8 (December 2018): e13305. https://doi.org/10.1111/petr.13305.
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  - Freischlag, Kyle, Paul M. Schroder, Brian Ezekian, Morgan L. Cox, Michael S. Mulvihill, Matthew G. Hartwig, and Stuart J. Knechtle. “Improved survival in simultaneous lung-liver recipients and candidates in the modern era of lung allocation.” J Surg Res 231 (November 2018): 395–402. https://doi.org/10.1016/j.jss.2018.06.007.
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  - Moris, Dimitrios, Diamantis Tsilimigras, Jenny Lim, Danielle Camastra, Aditya Nanavati, Stuart Knechtle, and Andrew Barbas. “Neuroendocrine carcinomas of the gallbladder: Lessons learnt from cases at opposite ends of the spectrum.” J Buon 23, no. 6 (November 2018): 1922–26.
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  - Patel, Yuval A., Jacqueline B. Henson, Julius M. Wilder, Jiayin Zheng, Schein-Chung Chow, Carl L. Berg, Stuart J. Knechtle, and Andrew J. Muir. “The impact of human leukocyte antigen donor and recipient serotyping and matching on liver transplant graft failure in primary sclerosing cholangitis, autoimmune hepatitis, and primary biliary cholangitis.” Clin Transplant 32, no. 10 (October 2018): e13388. https://doi.org/10.1111/ctr.13388.
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  - Wood, Amber M., Chad A. Grotegut, James Ronald, Waleska Pabon-Ramos, Christina Pedro, Stuart J. Knechtle, Ewa Wysokinska, Geoffrey D. Rubin, Carla W. Brady, and Jennifer B. Gilner. “Identification and Management of Abdominal Wall Varices in Pregnancy.” Obstet Gynecol 132, no. 4 (October 2018): 882–87. https://doi.org/10.1097/AOG.0000000000002805.
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  - Ezekian, Brian, Paul M. Schroder, Kyle Freischlag, Janghoon Yoon, Jean Kwun, and Stuart J. Knechtle. “Contemporary Strategies and Barriers to Transplantation Tolerance.” Transplantation 102, no. 8 (August 2018): 1213–22. https://doi.org/10.1097/TP.0000000000002242.
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  - Manook, Miriam, Jean Kwun, Steven Sacks, Anthony Dorling, Nizam Mamode, and Stuart Knechtle. “Innate networking: Thrombotic microangiopathy, the activation of coagulation and complement in the sensitized kidney transplant recipient.” Transplant Rev (Orlando) 32, no. 3 (July 2018): 119–26. https://doi.org/10.1016/j.trre.2018.01.001.
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  - Tambur, Anat R., Patricia Campbell, Frans H. Claas, Sandy Feng, Howard M. Gebel, Annette M. Jackson, Roslyn B. Mannon, et al. “Sensitization in Transplantation: Assessment of Risk (STAR) 2017 Working Group Meeting Report.” Am J Transplant 18, no. 7 (July 2018): 1604–14. https://doi.org/10.1111/ajt.14752.
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  - Barbas, Andrew S., Martin J. Dib, Aparna S. Rege, Deepak S. Vikraman, Debra L. Sudan, Stuart J. Knechtle, and John E. Scarborough. “The Volume-outcome Relationship in Deceased Donor Kidney Transplantation and Implications for Regionalization.” Ann Surg 267, no. 6 (June 2018): 1169–72. https://doi.org/10.1097/SLA.0000000000002351.
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  - Freischlag, Kyle William, Julia Messina, Brian Ezekian, Michael S. Mulvihill, Andrew Barbas, Carl Berg, Debra Sudan, John Reynolds, Matthew Hartwig, and Stuart Knechtle. “Single-Center Long-Term Analysis of Combined Liver-Lung Transplant Outcomes.” Transplant Direct 4, no. 5 (May 2018): e349. https://doi.org/10.1097/TXD.0000000000000785.
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  - “Kwun J, Burghuber C, Manook M, et al. Successful desensitization with proteasome inhibition and costimulation blockade in sensitized nonhuman primates. Blood Adv. 2017;1(24):2115-2119.” Blood Adv 2, no. 2 (January 23, 2018): 89. https://doi.org/10.1182/bloodadvances.2017015446.
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  - Kwun, Jean, Jaeberm Park, John S. Yi, Alton B. Farris, Allan D. Kirk, and Stuart J. Knechtle. “IL-21 Biased Alemtuzumab Induced Chronic Antibody-Mediated Rejection Is Reversed by LFA-1 Costimulation Blockade.” Front Immunol 9 (2018): 2323. https://doi.org/10.3389/fimmu.2018.02323.
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  - Kwun, Jean, Christopher Burghuber, Miriam Manook, Brian Ezekian, Jaeberm Park, Janghoon Yoon, John S. Yi, et al. “Successful desensitization with proteasome inhibition and costimulation blockade in sensitized nonhuman primates.” Blood Adv 1, no. 24 (November 14, 2017): 2115–19. https://doi.org/10.1182/bloodadvances.2017010991.
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  - Dendy, Meaghan S., Juan C. Camacho, Johannes M. Ludwig, Alyssa M. Krasinskas, Stuart J. Knechtle, and Hyun S. Kim. “Infiltrative Hepatocellular Carcinoma With Portal Vein Tumor Thrombosis Treated With a Single High-Dose Y90 Radioembolization and Subsequent Liver Transplantation Without a Recurrence.” Transplant Direct 3, no. 9 (September 2017): e206. https://doi.org/10.1097/TXD.0000000000000707.
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  - Ezekian, Brian, Michael S. Mulvihill, Kyle Freischlag, Babatunde A. Yerokun, Robert P. Davis, Matthew G. Hartwig, Stuart J. Knechtle, and Andrew S. Barbas. “Elevated HbA1c in donor organs from patients without a diagnosis of diabetes portends worse liver allograft survival.” Clin Transplant 31, no. 9 (September 2017). https://doi.org/10.1111/ctr.13047.
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  - Manook, M., J. Kwun, C. Burghuber, K. Samy, M. Mulvihill, J. Yoon, H. Xu, et al. “Thrombalexin: Use of a Cytotopic Anticoagulant to Reduce Thrombotic Microangiopathy in a Highly Sensitized Model of Kidney Transplantation.” Am J Transplant 17, no. 8 (August 2017): 2055–64. https://doi.org/10.1111/ajt.14234.
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  - Kwun, Jean, Christopher Burghuber, Miriam Manook, Neal Iwakoshi, Adriana Gibby, Jung Joo Hong, and Stuart Knechtle. “Humoral Compensation after Bortezomib Treatment of Allosensitized Recipients.” J Am Soc Nephrol 28, no. 7 (July 2017): 1991–96. https://doi.org/10.1681/ASN.2016070727.
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  - Kwun, Jean, Miriam Manook, Eugenia Page, Christopher Burghuber, Jungjoo Hong, and Stuart J. Knechtle. “Crosstalk Between T and B Cells in the Germinal Center After Transplantation.” Transplantation 101, no. 4 (April 2017): 704–12. https://doi.org/10.1097/TP.0000000000001588.
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  - Schadde, Erik, Christopher Tsatsaris, Marzena Swiderska-Syn, Stefan Breitenstein, Martin Urner, Roman Schimmer, Christa Booy, et al. “Hypoxia of the growing liver accelerates regeneration.” Surgery 161, no. 3 (March 2017): 666–79. https://doi.org/10.1016/j.surg.2016.05.018.
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  - Xing, Minzhi, Sonali Sakaria, Renumathy Dhanasekaran, Samir Parekh, James Spivey, Stuart J. Knechtle, Di Zhang, and Hyun S. Kim. “Bridging Locoregional Therapy Prolongs Survival in Patients Listed for Liver Transplant with Hepatocellular Carcinoma.” Cardiovasc Intervent Radiol 40, no. 3 (March 2017): 410–20. https://doi.org/10.1007/s00270-016-1505-0.
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  - Schroder, Paul M., Brian Ezekian, Mandy Ford, Stuart J. Knechtle, and Jean Kwun. “Commentary: Belatacept Does Not Inhibit Follicular T Cell-Dependent B-Cell Differentiation in Kidney Transplantation.” Front Immunol 8 (2017): 1615. https://doi.org/10.3389/fimmu.2017.01615.
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  - Barbas, A. S., and S. J. Knechtle. “Expanding the Donor Pool With Normothermic Ex Vivo Liver Perfusion: The Future Is Now.” Am J Transplant 16, no. 11 (November 2016): 3075–76. https://doi.org/10.1111/ajt.13959.
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  - Demetris, A. J., C. Bellamy, S. G. Hübscher, J. O’Leary, P. S. Randhawa, S. Feng, D. Neil, et al. “2016 Comprehensive Update of the Banff Working Group on Liver Allograft Pathology: Introduction of Antibody-Mediated Rejection.” Am J Transplant 16, no. 10 (October 2016): 2816–35. https://doi.org/10.1111/ajt.13909.
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  - Oh, B., J. Yoon, A. Farris, A. Kirk, S. Knechtle, and J. Kwun. “Rapamycin Interferes With Postdepletion Regulatory T Cell Homeostasis and Enhances DSA Formation Corrected by CTLA4-Ig.” Am J Transplant 16, no. 9 (September 2016): 2612–23. https://doi.org/10.1111/ajt.13789.
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  - Knechtle, S. J., and R. L. Fairchild. “Regulating T Cell Behavior.” Am J Transplant 16, no. 7 (July 2016): 1949–50. https://doi.org/10.1111/ajt.13724.
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  - Burghuber, C. K., J. Kwun, E. J. Page, M. Manook, A. C. Gibby, F. V. Leopardi, M. Song, et al. “Antibody-Mediated Rejection in Sensitized Nonhuman Primates: Modeling Human Biology.” Am J Transplant 16, no. 6 (June 2016): 1726–38. https://doi.org/10.1111/ajt.13688.
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  - Ludwig, Johannes M., Stuart J. Knechtle, and Hyun S. Kim. “Reply to: "Percutaneous Management of Benign Biliary Strictures: Is It Time to Focus on Reducing Procedure Invasiveness?".” J Vasc Interv Radiol 27, no. 6 (June 2016): 936–37. https://doi.org/10.1016/j.jvir.2016.03.003.
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  - Ludwig, Johannes M., Grant R. Webber, Stuart J. Knechtle, James R. Spivey, Minzhi Xing, and Hyun S. Kim. “Percutaneous Management of Benign Biliary Strictures with Large-Bore Catheters: Comparison between Patients with and without Orthotopic Liver Transplantation.” J Vasc Interv Radiol 27, no. 2 (February 2016): 219-225.e1. https://doi.org/10.1016/j.jvir.2015.10.021.
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  - Suhre, Karsten, Joseph E. Schwartz, Vijay K. Sharma, Qiuying Chen, John R. Lee, Thangamani Muthukumar, Darshana M. Dadhania, et al. “Urine Metabolite Profiles Predictive of Human Kidney Allograft Status.” J Am Soc Nephrol 27, no. 2 (February 2016): 626–36. https://doi.org/10.1681/ASN.2015010107.
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  - Halazun, K. J., A. K. Mathur, A. A. Rana, A. B. Massie, S. Mohan, R. E. Patzer, J. P. Wedd, et al. “One Size Does Not Fit All--Regional Variation in the Impact of the Share 35 Liver Allocation Policy.” Am J Transplant 16, no. 1 (January 2016): 137–42. https://doi.org/10.1111/ajt.13500.
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  - Kwun, Jean, Alton B. Farris, Hyunjin Song, William T. Mahle, William J. Burlingham, and Stuart J. Knechtle. “Impact of Leukocyte Function-Associated Antigen-1 Blockade on Endogenous Allospecific T Cells to Multiple Minor Histocompatibility Antigen Mismatched Cardiac Allograft.” Transplantation 99, no. 12 (December 2015): 2485–93. https://doi.org/10.1097/TP.0000000000000805.
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  - Newell, K. A., A. Asare, I. Sanz, C. Wei, A. Rosenberg, Z. Gao, S. Kanaparthi, et al. “Longitudinal studies of a B cell-derived signature of tolerance in renal transplant recipients.” Am J Transplant 15, no. 11 (November 2015): 2908–20. https://doi.org/10.1111/ajt.13480.
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  - Reed, Alan, William C. Chapman, Stuart Knechtle, Kenneth Chavin, Richard Gilroy, and Goran B. G. Klintmalm. “Equalizing MELD Scores Over Broad Geographies Is Not the Most Efficacious Way to Allocate a Scarce Resource in a Value-based Environment.” Ann Surg 262, no. 2 (August 2015): 220–23. https://doi.org/10.1097/SLA.0000000000001331.
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  - Kokabi, Nima, Juan C. Camacho, Minzhi Xing, Bassel F. El-Rayes, James R. Spivey, Stuart J. Knechtle, and Hyun S. Kim. “Open-label prospective study of the safety and efficacy of glass-based yttrium 90 radioembolization for infiltrative hepatocellular carcinoma with portal vein thrombosis.” Cancer 121, no. 13 (July 1, 2015): 2164–74. https://doi.org/10.1002/cncr.29275.
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  - Kwun, J., E. Page, J. J. Hong, A. Gibby, J. Yoon, A. B. Farris, F. Villinger, and S. Knechtle. “Neutralizing BAFF/APRIL with atacicept prevents early DSA formation and AMR development in T cell depletion induced nonhuman primate AMR model.” Am J Transplant 15, no. 3 (March 2015): 815–22. https://doi.org/10.1111/ajt.13045.
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  - Velazquez, Victoria M., Luke S. Uebelhoer, Manoj Thapa, Chris C. Ibegbu, Cynthia Courtney, Steven E. Bosinger, Joseph F. Magliocca, et al. “Systems biological analyses reveal the hepatitis C virus (HCV)-specific regulation of hematopoietic development.” Hepatology 61, no. 3 (March 2015): 843–56. https://doi.org/10.1002/hep.27575.
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  - Burghuber, C. K., T. K. Roberts, and S. J. Knechtle. “The clinical relevance of alloantibody in liver transplantation.” Transplant Rev (Orlando) 29, no. 1 (January 2015): 16–22. https://doi.org/10.1016/j.trre.2014.06.001.
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  - Medbery, Rachel L., Tatiana S. Chadid, John F. Sweeney, Stuart J. Knechtle, David A. Kooby, Shishir K. Maithel, Edward Lin, and Juan M. Sarmiento. “Laparoscopic vs open right hepatectomy: a value-based analysis.” J Am Coll Surg 218, no. 5 (May 2014): 929–39. https://doi.org/10.1016/j.jamcollsurg.2014.01.045.
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  - Squires, Malcolm H., Steven I. Hanish, Sarah B. Fisher, Cristen Garrett, David A. Kooby, Juan M. Sarmiento, Kenneth Cardona, et al. “Transplant versus resection for the management of hepatocellular carcinoma meeting Milan Criteria in the MELD exception era at a single institution in a UNOS region with short wait times.” J Surg Oncol 109, no. 6 (May 2014): 533–41. https://doi.org/10.1002/jso.23531.
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  - O’Leary, J. G., A. J. Demetris, L. S. Friedman, H. M. Gebel, P. F. Halloran, A. D. Kirk, S. J. Knechtle, et al. “The role of donor-specific HLA alloantibodies in liver transplantation.” Am J Transplant 14, no. 4 (April 2014): 779–87. https://doi.org/10.1111/ajt.12667.
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  - Kim, E. J., J. Kwun, A. C. Gibby, J. J. Hong, A. B. Farris, N. N. Iwakoshi, F. Villinger, A. D. Kirk, and S. J. Knechtle. “Costimulation blockade alters germinal center responses and prevents antibody-mediated rejection.” Am J Transplant 14, no. 1 (January 2014): 59–69. https://doi.org/10.1111/ajt.12526.
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  - Kim, Steven C., Eugenia K. Page, and Stuart J. Knechtle. “Urine proteomics in kidney transplantation.” Transplant Rev (Orlando) 28, no. 1 (January 2014): 15–20. https://doi.org/10.1016/j.trre.2013.10.004.
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  - Thammana, Rekha V., Stuart J. Knechtle, Rene Romero, Thomas G. Heffron, Caroline T. Daniels, and Rachel E. Patzer. “Racial and socioeconomic disparities in pediatric and young adult liver transplant outcomes.” Liver Transpl 20, no. 1 (January 2014): 100–115. https://doi.org/10.1002/lt.23769.
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  - Tanaka, H., G. -. X. Yang, N. Iwakoshi, S. J. Knechtle, K. Kawata, K. Tsuneyama, P. Leung, et al. “Anti-CD40 ligand monoclonal antibody delays the progression of murine autoimmune cholangitis.” Clin Exp Immunol 174, no. 3 (December 2013): 364–71. https://doi.org/10.1111/cei.12193.
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  - Tyson, Mark D., Eric S. Wisenbaugh, Paul E. Andrews, Erik P. Castle, and Mitchell R. Humphreys. “Simultaneous kidney transplantation and bilateral native nephrectomy for polycystic kidney disease.” J Urol 190, no. 6 (December 2013): 2170–74. https://doi.org/10.1016/j.juro.2013.05.057.
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  - Page, Eugenia K., Cynthia L. Courtney, Prachi Sharma, Jennifer Cheeseman, Joe B. Jenkins, Elizabeth Strobert, and Stuart J. Knechtle. “Post-transplant lymphoproliferative disorder associated with immunosuppressive therapy for renal transplantation in rhesus macaques (Macaca mulatta).” Exp Toxicol Pathol 65, no. 7–8 (November 2013): 1019–24. https://doi.org/10.1016/j.etp.2013.02.005.
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  - Suthanthiran, Manikkam, Joseph E. Schwartz, Ruchuang Ding, Michael Abecassis, Darshana Dadhania, Benjamin Samstein, Stuart J. Knechtle, et al. “Urinary-cell mRNA profile and acute cellular rejection in kidney allografts.” N Engl J Med 369, no. 1 (July 4, 2013): 20–31. https://doi.org/10.1056/NEJMoa1215555.
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  - Page, Eugenia, Jean Kwun, Byoungchol Oh, and Stuart Knechtle. “Lymphodepletional strategies in transplantation.” Cold Spring Harb Perspect Med 3, no. 7 (July 1, 2013). https://doi.org/10.1101/cshperspect.a015511.
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  - Turner, Alexandra P., and Stuart J. Knechtle. “Induction immunosuppression in liver transplantation: a review.” Transpl Int 26, no. 7 (July 2013): 673–83. https://doi.org/10.1111/tri.12100.
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  - Onor, Ifeanyichukwu O., Sarah B. Todd, Erika Meredith, Sebastian D. Perez, Aneesh K. Mehta, G. Marshall Lyon, Stuart J. Knechtle, and Steven I. Hanish. “Evaluation of clinical outcomes of prophylactic versus preemptive cytomegalovirus strategy in liver transplant recipients.” Transpl Int 26, no. 6 (June 2013): 592–600. https://doi.org/10.1111/tri.12101.
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  - Badell, I. R., S. I. Hanish, C. B. Hughes, W. R. Hewitt, R. T. Chung, J. R. Spivey, and S. J. Knechtle. “Domino liver transplantation in maple syrup urine disease: a case report and review of the literature.” Transplant Proc 45, no. 2 (March 2013): 806–9. https://doi.org/10.1016/j.transproceed.2012.04.031.
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  - Dhirapong, Amy, Guo-Xiang Yang, Steven Nadler, Weici Zhang, Koichi Tsuneyama, Patrick Leung, Stuart Knechtle, et al. “Therapeutic effect of cytotoxic T lymphocyte antigen 4/immunoglobulin on a murine model of primary biliary cirrhosis.” Hepatology 57, no. 2 (February 2013): 708–15. https://doi.org/10.1002/hep.26067.
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  - Morris, P. J., and S. J. Knechtle. “Kidney transplantation-principles and practice, seventh edition.” Kidney Transplantation Principles and Practice, Seventh Edition, January 1, 2013, 1–758.
  - Morris, P. J., and S. J. Knechtle. “Preface to the seventh edition.” Kidney Transplantation Principles and Practice, Seventh Edition, January 1, 2013, xi–xi. https://doi.org/10.1016/B978-1-4557-4096-3.09985-2.
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  - Velazquez, Victoria M., Huiming Hon, Chris Ibegbu, Stuart J. Knechtle, Allan D. Kirk, and Arash Grakoui. “Hepatic enrichment and activation of myeloid dendritic cells during chronic hepatitis C virus infection.” Hepatology 56, no. 6 (December 2012): 2071–81. https://doi.org/10.1002/hep.25904.
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  - Gupta, Nitika A., Vasantha L. Kolachala, Rong Jiang, Carlos Abramowsky, Rene Romero, Nimita Fifadara, Frank Anania, Stuart Knechtle, and Allan Kirk. “The glucagon-like peptide-1 receptor agonist Exendin 4 has a protective role in ischemic injury of lean and steatotic liver by inhibiting cell death and stimulating lipolysis.” Am J Pathol 181, no. 5 (November 2012): 1693–1701. https://doi.org/10.1016/j.ajpath.2012.07.015.
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  - Magliocca, J. F., L. K. Kayler, S. I. Hanish, S. J. Knechtle, and J. D. Schold. “Significantly Greater Hazard Associated with the Use of Older Donor Livers in HCV+ Recipients.” Transplantation Journal 94, no. 10S (November 2012): 426–426. https://doi.org/10.1097/00007890-201211271-00804.
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  - Magliocca, J. F., L. K. Kayler, S. I. Hanish, S. J. Knechtle, and J. D. Schold. “Significantly Greater Hazard Associated with the Use of Older Donor Livers in HCV+ Recipients.” Transplantation Journal 94, no. 10S (November 2012): 107–107. https://doi.org/10.1097/00007890-201211271-00196.
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  - Kwun, J., B. C. Oh, A. C. Gibby, R. Ruhil, V. T. Lu, D. W. Kim, E. K. Page, et al. “Patterns of de novo allo B cells and antibody formation in chronic cardiac allograft rejection after alemtuzumab treatment.” Am J Transplant 12, no. 10 (October 2012): 2641–51. https://doi.org/10.1111/j.1600-6143.2012.04181.x.
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  - Page, E. K., A. J. Page, J. Kwun, A. C. Gibby, F. Leopardi, J. B. Jenkins, E. A. Strobert, et al. “Enhanced de novo alloantibody and antibody-mediated injury in rhesus macaques.” Am J Transplant 12, no. 9 (September 2012): 2395–2405. https://doi.org/10.1111/j.1600-6143.2012.04074.x.
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  - Page, Eugenia K., Wasim A. Dar, and Stuart J. Knechtle. “Biologics in organ transplantation.” Transpl Int 25, no. 7 (July 2012): 707–19. https://doi.org/10.1111/j.1432-2277.2012.01456.x.
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  - Kwun, Jean, Pinar Bulut, Eugenia Kim, Wasim Dar, Byoungchol Oh, Ravi Ruhil, Neal Iwakoshi, and Stuart J. Knechtle. “The role of B cells in solid organ transplantation.” Semin Immunol 24, no. 2 (April 2012): 96–108. https://doi.org/10.1016/j.smim.2011.08.022.
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  - Page, Eugenia K., Wasim A. Dar, and Stuart J. Knechtle. “Tolerogenic therapies in transplantation.” Front Immunol 3 (2012): 198. https://doi.org/10.3389/fimmu.2012.00198.
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  - Becker-Weidman, David J. S., Bobby Kalb, Puneet Sharma, Hiroumi D. Kitajima, Christina R. Lurie, Zhengjia Chen, James R. Spivey, et al. “Hepatocellular carcinoma lesion characterization: single-institution clinical performance review of multiphase gadolinium-enhanced MR imaging--comparison to prior same-center results after MR systems improvements.” Radiology 261, no. 3 (December 2011): 824–33. https://doi.org/10.1148/radiol.11110157.
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  - Kwun, Jean, Subramaniam Malarkannan, William J. Burlingham, and Stuart J. Knechtle. “Primary vascularization of the graft determines the immunodominance of murine minor H antigens during organ transplantation.” J Immunol 187, no. 8 (October 15, 2011): 3997–4006. https://doi.org/10.4049/jimmunol.1003918.
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  - Hanish, Steven I., and Stuart J. Knechtle. “Liver transplantation for the treatment of hepatocellular carcinoma.” Oncology (Williston Park) 25, no. 8 (July 2011): 752–57.
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  - Dar, W., A. Agarwal, C. Watkins, H. M. Gebel, R. A. Bray, K. E. Kokko, T. C. Pearson, and S. J. Knechtle. “Donor-directed MHC class I antibody is preferentially cleared from sensitized recipients of combined liver/kidney transplants.” Am J Transplant 11, no. 4 (April 2011): 841–47. https://doi.org/10.1111/j.1600-6143.2011.03467.x.
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  - Knechtle, S. J. “Immunoregulation and tolerance.” Transplant Proc 42, no. 9 Suppl (November 2010): S13–15. https://doi.org/10.1016/j.transproceed.2010.07.039.
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  - Dhanasekaran, Renumathy, Vinit Khanna, David A. Kooby, James R. Spivey, Samir Parekh, Stuart J. Knechtle, John D. Carew, John S. Kauh, and Hyun S. Kim. “The effectiveness of locoregional therapies versus supportive care in maintaining survival within the Milan criteria in patients with hepatocellular carcinoma.” J Vasc Interv Radiol 21, no. 8 (August 2010): 1197–1204. https://doi.org/10.1016/j.jvir.2010.04.018.
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  - Niederhaus, Silke V., Debra D. Bloom, Zhen Chang, Huaizhong Hu, Sharon M. Bartosh, and Stuart J. Knechtle. “Cytokine kinetics profiling in pediatric renal transplant recipients.” Pediatr Transplant 14, no. 5 (August 2010): 636–45. https://doi.org/10.1111/j.1399-3046.2010.01309.x.
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  - Haustein, Silke, Jean Kwun, John Fechner, Ayhan Kayaoglu, Jean-Pierre Faure, Drew Roenneburg, Jose Torrealba, and Stuart J. Knechtle. “Interleukin-15 receptor blockade in non-human primate kidney transplantation.” Transplantation 89, no. 8 (April 27, 2010): 937–44. https://doi.org/10.1097/TP.0b013e3181d05a58.
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  - Radziewicz, Henry, Chris C. Ibegbu, Huiming Hon, Nathalie Bédard, Julie Bruneau, Kimberly A. Workowski, Stuart J. Knechtle, et al. “Transient CD86 expression on hepatitis C virus-specific CD8+ T cells in acute infection is linked to sufficient IL-2 signaling.” J Immunol 184, no. 5 (March 1, 2010): 2410–22. https://doi.org/10.4049/jimmunol.0902994.
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  - Safdar, Nasia, Jeannina Smith, Valerie Knasinski, Colleen Sherkow, Casey Herrforth, Stuart Knechtle, and David Andes. “Infections after the use of alemtuzumab in solid organ transplant recipients: a comparative study.” Diagn Microbiol Infect Dis 66, no. 1 (January 2010): 7–15. https://doi.org/10.1016/j.diagmicrobio.2009.08.017.
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  - Kwun, Jean, and Stuart J. Knechtle. “Overcoming Chronic Rejection-Can it B?” Transplantation 88, no. 8 (October 27, 2009): 955–61. https://doi.org/10.1097/TP.0b013e3181b96646.
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  - Kiani, Adnan N., Kristen Johnson, Catherine Chen, Edward Diehl, Huaizhong Hu, Ganesh Vasudevan, Sukhminder Singh, Laurence S. Magder, Stuart J. Knechtle, and Michelle Petri. “Urine osteoprotegerin and monocyte chemoattractant protein-1 in lupus nephritis.” J Rheumatol 36, no. 10 (October 2009): 2224–30. https://doi.org/10.3899/jrheum.081112.
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  - Bloom, D., Z. Chang, K. Pauly, J. Kwun, J. Fechner, C. Hayes, M. Samaniego, and S. Knechtle. “BAFF is increased in renal transplant patients following treatment with alemtuzumab.” Am J Transplant 9, no. 8 (August 2009): 1835–45. https://doi.org/10.1111/j.1600-6143.2009.02710.x.
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  - Hu, Huaizhong, Jean Kwun, Brian D. Aizenstein, and Stuart J. Knechtle. “Noninvasive detection of acute and chronic injuries in human renal transplant by elevation of multiple cytokines/chemokines in urine.” Transplantation 87, no. 12 (June 27, 2009): 1814–20. https://doi.org/10.1097/TP.0b013e3181a66b3e.
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  - Knechtle, S. J., J. Pascual, D. D. Bloom, J. R. Torrealba, E. Jankowska-Gan, W. J. Burlingham, J. Kwun, et al. “Early and limited use of tacrolimus to avoid rejection in an alemtuzumab and sirolimus regimen for kidney transplantation: clinical results and immune monitoring.” Am J Transplant 9, no. 5 (May 2009): 1087–98. https://doi.org/10.1111/j.1600-6143.2009.02581.x.
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  - Knechtle, Stuart J., and Jean Kwun. “Unique aspects of rejection and tolerance in liver transplantation.” Semin Liver Dis 29, no. 1 (February 2009): 91–101. https://doi.org/10.1055/s-0029-1192058.
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  - Pascual, Julio, John D. Pirsch, Jon S. Odorico, José R. Torrealba, Arjang Djamali, Yolanda T. Becker, Barbara Voss, et al. “Alemtuzumab induction and antibody-mediated kidney rejection after simultaneous pancreas-kidney transplantation.” Transplantation 87, no. 1 (January 15, 2009): 125–32. https://doi.org/10.1097/TP.0b013e31818c6db0.
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  - Bloom, Debra D., Kyle Pauly, Zhen Chang, John H. Fechner, Jean Kwun, Millie Samaniego, and Stuart J. Knechtle. “BAFF Dysregulation in Renal Transplant Patients Treated with Campath-1H.” American Journal of Transplantation 9 (January 1, 2009): 226–226.
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  - Spier, Bret J., Patrick R. Pfau, Katelin R. Lorenze, Stuart J. Knechtle, and Adnan Said. “Risk factors and outcomes in post-liver transplantation bile duct stones and casts: A case-control study.” Liver Transpl 14, no. 10 (October 2008): 1461–65. https://doi.org/10.1002/lt.21511.
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  - Kwun, J., S. M. Hazinedaroglu, E. Schadde, H. A. Kayaoglu, J. Fechner, H. Z. Hu, D. Roenneburg, et al. “Unaltered graft survival and intragraft lymphocytes infiltration in the cardiac allograft of Cxcr3-/- mouse recipients.” Am J Transplant 8, no. 8 (August 2008): 1593–1603. https://doi.org/10.1111/j.1600-6143.2008.02250.x.
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  - Magliocca, J. F., J. S. Odorico, J. D. Pirsch, Y. T. Becker, S. J. Knechtle, G. E. Leverson, and H. W. Sollinger. “A comparison of alemtuzumab with basiliximab induction in simultaneous pancreas-kidney transplantation.” Am J Transplant 8, no. 8 (August 2008): 1702–10. https://doi.org/10.1111/j.1600-6143.2008.02299.x.
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  - Pascual, J., D. Bloom, J. Torrealba, R. Brahmbhatt, Z. Chang, H. W. Sollinger, and S. J. Knechtle. “Calcineurin inhibitor withdrawal after renal transplantation with alemtuzumab: clinical outcomes and effect on T-regulatory cells.” Am J Transplant 8, no. 7 (July 2008): 1529–36. https://doi.org/10.1111/j.1600-6143.2008.02260.x.
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  - Schadde, Erik, Anthony M. D’Alessandro, Stuart J. Knechtle, Jon Odorico, Yolanda Becker, John Pirsch, Hans Sollinger, and Luis A. Fernandez. “Alemtuzumab induction and triple maintenance immunotherapy in kidney transplantation from donors after cardiac death.” Transpl Int 21, no. 7 (July 2008): 625–36. https://doi.org/10.1111/j.1432-2277.2008.00642.x.
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  - Pescovitz, Mark D., Stuart Knechtle, Steven R. Alexander, Paul Colombani, Tom Nevins, Keith Nieforth, and M René Bouw. “Safety and pharmacokinetics of daclizumab in pediatric renal transplant recipients.” Pediatr Transplant 12, no. 4 (June 2008): 447–55. https://doi.org/10.1111/j.1399-3046.2007.00830.x.
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  - Bloom, D. D., Z. Chang, J. H. Fechner, W. Dar, S. P. Polster, J. Pascual, L. A. Turka, and S. J. Knechtle. “CD4+ CD25+ FOXP3+ regulatory T cells increase de novo in kidney transplant patients after immunodepletion with Campath-1H.” Am J Transplant 8, no. 4 (April 2008): 793–802. https://doi.org/10.1111/j.1600-6143.2007.02134.x.
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  - Pascual, Julio, Milagros D. Samaniego, José R. Torrealba, Jon S. Odorico, Arjang Djamali, Yolanda T. Becker, Barbara Voss, et al. “Antibody-mediated rejection of the kidney after simultaneous pancreas-kidney transplantation.” J Am Soc Nephrol 19, no. 4 (April 2008): 812–24. https://doi.org/10.1681/ASN.2007070736.
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  - Gingles, Bruce, and Stuart Knechtle. “Surgical invention and commercialization.” Surgery 143, no. 2 (February 2008): 175–81. https://doi.org/10.1016/j.surg.2007.11.017.
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  - Brem-Exner, Beate G., Christine Sattler, James A. Hutchinson, Gudrun E. Koehl, Katharina Kronenberg, Stefan Farkas, Seiichiro Inoue, et al. “Macrophages driven to a novel state of activation have anti-inflammatory properties in mice.” J Immunol 180, no. 1 (January 1, 2008): 335–49. https://doi.org/10.4049/jimmunol.180.1.335.
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  - Haustein, Silke V., Amanda J. Kolterman, Jeffrey J. Sundblad, John H. Fechner, and Stuart J. Knechtle. “Nonhuman primate infections after organ transplantation.” Ilar J 49, no. 2 (2008): 209–19. https://doi.org/10.1093/ilar.49.2.209.
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  - Yagci, G., L. A. Fernandez, S. J. Knechtle, A. M. D’Alessandro, L. T. Chin, A. I. Musat, M. R. Lucey, et al. “The impact of donor variables on the outcome of orthotopic liver transplantation for hepatitis C.” Transplant Proc 40, no. 1 (January 2008): 219–23. https://doi.org/10.1016/j.transproceed.2007.11.058.
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  - Kwun, Jean, Huaizhong Hu, Erik Schadde, Drew Roenneburg, Kathleen A. Sullivan, Julie DeMartino, William J. Burlingham, and Stuart J. Knechtle. “Altered distribution of H60 minor H antigen-specific CD8 T cells and attenuated chronic vasculopathy in minor histocompatibility antigen mismatched heart transplantation in Cxcr3-/- mouse recipients.” J Immunol 179, no. 12 (December 15, 2007): 8016–25. https://doi.org/10.4049/jimmunol.179.12.8016.
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  - Molitor-Dart, Melanie L., Joachim Andrassy, Jean Kwun, H Ayhan Kayaoglu, Drew A. Roenneburg, Lynn D. Haynes, Jose R. Torrealba, et al. “Developmental exposure to noninherited maternal antigens induces CD4+ T regulatory cells: relevance to mechanism of heart allograft tolerance.” J Immunol 179, no. 10 (November 15, 2007): 6749–61. https://doi.org/10.4049/jimmunol.179.10.6749.
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  - Kirk, A. D., W. S. Cherikh, M. Ring, G. Burke, D. Kaufman, S. J. Knechtle, S. Potdar, R. Shapiro, V. R. Dharnidharka, and H. M. Kauffman. “Dissociation of depletional induction and posttransplant lymphoproliferative disease in kidney recipients treated with alemtuzumab.” Am J Transplant 7, no. 11 (November 2007): 2619–25. https://doi.org/10.1111/j.1600-6143.2007.01972.x.
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  - D’Alessandro, A. M., S. J. Knechtle, L Thomas Chin, L. A. Fernandez, G. Yagci, G. Leverson, and M. Kalayoglu. “Liver transplantation in pediatric patients: twenty years of experience at the University of Wisconsin.” Pediatr Transplant 11, no. 6 (September 2007): 661–70. https://doi.org/10.1111/j.1399-3046.2007.00737.x.
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  - Pascual, Julio, Joshua D. Mezrich, Arjang Djamali, Glen Leverson, L Thomas Chin, José Torrealba, Debra Bloom, et al. “Alemtuzumab induction and recurrence of glomerular disease after kidney transplantation.” Transplantation 83, no. 11 (June 15, 2007): 1429–34. https://doi.org/10.1097/01.tp.0000264554.39645.74.
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  - Bartosh, Sharon M., Cheryl P. Sanchez, Hans W. Sollinger, and Stuart J. Knechtle. “Pilot trial of steroid free immunosuppression with campath-1H in low risk pediatric kidney transplants (TX).” Pediatric Transplantation 11 (May 1, 2007): 37–37.
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  - Dar, Wasim A., and Stuart J. Knechtle. “CXCR3-mediated T-cell chemotaxis involves ZAP-70 and is regulated by signalling through the T-cell receptor.” Immunology 120, no. 4 (April 2007): 467–85. https://doi.org/10.1111/j.1365-2567.2006.02534.x.
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  - Schadde, E., and S. J. Knechtle. “Review: chemokines in transplantation.” Transplantation Reviews 21, no. 2 (April 1, 2007): 107–18. https://doi.org/10.1016/j.trre.2007.03.004.
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  - Sollinger, H. W., Y. T. Becker, W. Burlingham, A. M. D’Alessandro, L. A. Fernandez, D. Hullett, S. J. Knechtle, et al. “The history of the University of Wisconsin transplant program.” Clin Transpl, 2007, 271–87.
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  - Fechner, J. H., S. V. Haustein, and S. J. Knechtle. “Immunosuppression in nonhuman primates.” Transplantation Reviews 20, no. 3 (July 1, 2006): 131–38. https://doi.org/10.1016/j.trre.2006.06.005.
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  - Kwun, Jean, Stuart J. Knechtle, and Huaizhong Hu. “Determination of the functional status of alloreactive T cells by interferon-gamma kinetics.” Transplantation 81, no. 4 (February 27, 2006): 590–98. https://doi.org/10.1097/01.tp.0000196353.04494.14.
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  - Bloom, Debra D., Huaizhong Hu, John H. Fechner, and Stuart J. Knechtle. “T-lymphocyte alloresponses of Campath-1H-treated kidney transplant patients.” Transplantation 81, no. 1 (January 15, 2006): 81–87. https://doi.org/10.1097/01.tp.0000191940.13473.59.
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  - Schadde, Erik, Anthony M. d’Alessandro, Alexandru I. Musat, Jose R. Torrealba, and Stuart J. Knechtle. “Donor-specific HLA-antibody-mediated humoral rejection in a liver transplant recipient fully reversed with plasmapheresis and immunoglobulin.” Clin Transpl, 2006, 479–82.
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  - Knechtle, Stuart J. “How does alemtuzumab affect long-term graft and patient outcomes after deceased-donor kidney transplantation?” Nat Clin Pract Nephrol 1, no. 2 (December 2005): 74–75. https://doi.org/10.1038/ncpneph0052.
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  - Fernandez, Luis A., Antonio Di Carlo, Jon S. Odorico, Glen E. Leverson, Brian D. Shames, Yolanda T. Becker, L Thomas Chin, et al. “Simultaneous pancreas-kidney transplantation from donation after cardiac death: successful long-term outcomes.” Ann Surg 242, no. 5 (November 2005): 716–23. https://doi.org/10.1097/01.sla.0000186175.84788.50.
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  - Bartosh, Sharon M., Stuart J. Knechtle, and Hans W. Sollinger. “Campath-1H use in pediatric renal transplantation.” Am J Transplant 5, no. 6 (June 2005): 1569–73. https://doi.org/10.1111/j.1600-6143.2005.00879.x.
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  - Torrealba, Jose R., Matthew Colburn, Susan Golner, Zhen Chang, Tara Scheunemann, John H. Fechner, Drew Roenneburg, et al. “Selenium-binding protein-1 in smooth muscle cells is downregulated in a rhesus monkey model of chronic allograft nephropathy.” Am J Transplant 5, no. 1 (January 2005): 58–67. https://doi.org/10.1111/j.1600-6143.2004.00651.x.
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  - Kanmaz, Turan, Ping Feng, Jose Torrealba, Jean Kwun, John H. Fechner, Jacqueline M. Schultz, Yinchen Dong, et al. “Surveillance of acute rejection in baboon renal transplantation by elevation of interferon-gamma inducible protein-10 and monokine induced by interferon-gamma in urine.” Transplantation 78, no. 7 (October 15, 2004): 1002–7. https://doi.org/10.1097/01.tp.0000134397.55564.71.
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  - Knechtle, Stuart J., Luis A. Fernandez, John D. Pirsch, Bryan N. Becker, L Thomas Chin, Yolanda T. Becker, Jon S. Odorico, Anthony M. D’alessandro, and Hans W. Sollinger. “Campath-1H in renal transplantation: The University of Wisconsin experience.” Surgery 136, no. 4 (October 2004): 754–60. https://doi.org/10.1016/j.surg.2004.06.015.
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  - Cai, Junchao, Paul I. Terasaki, Debra D. Bloom, Jose R. Torrealba, Andreas Friedl, Hans W. Sollinger, and Stuart J. Knechtle. “Correlation between human leukocyte antigen antibody production and serum creatinine in patients receiving sirolimus monotherapy after Campath-1H induction.” Transplantation 78, no. 6 (September 27, 2004): 919–24. https://doi.org/10.1097/01.tp.0000134398.86243.81.
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  - Fernandez, Luis A., Masahiro Tsuchida, Eric Manthei, John H. Fechner, Terry D. Oberley, Glen E. Leverson, Stuart J. Knechtle, and Majed M. Hamawy. “Immune status assay (ISA): a noninvasive procedure for studying allograft rejection.” Transpl Immunol 13, no. 2 (September 2004): 147–54. https://doi.org/10.1016/j.trim.2004.05.007.
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  - Hu, Huaizhong, Brian D. Aizenstein, Alice Puchalski, Jeanine A. Burmania, Majed M. Hamawy, and Stuart J. Knechtle. “Elevation of CXCR3-binding chemokines in urine indicates acute renal-allograft dysfunction.” Am J Transplant 4, no. 3 (March 2004): 432–37. https://doi.org/10.1111/j.1600-6143.2004.00354.x.
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  - Tsuchida, M., E. R. Manthei, T. Alam, S. J. Knechtle, and M. M. Hamawy. “T cell activation up-regulates the expression of the focal adhesion kinase Pyk2: opposing roles for the activation of protein kinase C and the increase in intracellular Ca2+.” J Immunol 163, no. 12 (December 15, 1999): 6640–50.
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  - DeLone, D. R., R. A. Goldstein, G. Petermann, M. S. Salamat, J. M. Miles, S. J. Knechtle, and W. D. Brown. “Disseminated aspergillosis involving the brain: distribution and imaging characteristics.” Ajnr Am J Neuroradiol 20, no. 9 (October 1999): 1597–1604.
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  - Knechtle, S. J., A. M. D’Alessandro, M. J. Armbrust, A. Musat, and M. Kalayoglu. “Surgical portosystemic shunts for treatment of portal hypertensive bleeding: outcome and effect on liver function.” Surgery 126, no. 4 (October 1999): 708–11.
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  - Hamawy, M. M., M. Tsuchida, E. R. Manthei, Y. Dong, J. E. Fechner, and J. S. Knechtle. “Activation of T lymphocytes for adhesion and cytokine expression by toxin-conjugated anti-CD3 monoclonal antibodies.” Transplantation 68, no. 5 (September 15, 1999): 693–98. https://doi.org/10.1097/00007890-199909150-00016.
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  - Becker, B. N., J. S. Odorico, Y. T. Becker, G. Leverson, J. C. McDermott, T. Grist, I. Sproat, et al. “Peripheral vascular disease and renal transplant artery stenosis: a reappraisal of transplant renovascular disease.” Clin Transplant 13, no. 4 (August 1999): 349–55. https://doi.org/10.1034/j.1399-0012.1999.130412.x.
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  - Becker, B. N., Y. T. Becker, D. M. Heisey, G. E. Leverson, B. H. Collins, J. S. Odorico, A. M. D’Alessandro, S. J. Knechtle, J. D. Pirsch, and H. W. Sollinger. “The impact of hypoalbuminemia in kidney-pancreas transplant recipients.” Transplantation 68, no. 1 (July 15, 1999): 72–75. https://doi.org/10.1097/00007890-199907150-00014.
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  - Tsuchida, M., E. R. Manthei, S. J. Knechtle, and M. M. Hamawy. “CD28 ligation induces rapid tyrosine phosphorylation of the linker molecule LAT in the absence of Syk and ZAP-70 tyrosine phosphorylation.” Eur J Immunol 29, no. 7 (July 1999): 2354–59. https://doi.org/10.1002/(SICI)1521-4141(199907)29:07<2354::AID-IMMU2354>3.0.CO;2-P.
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  - Kirk, A. D., L. C. Burkly, D. S. Batty, R. E. Baumgartner, J. D. Berning, K. Buchanan, J. H. Fechner, et al. “Treatment with humanized monoclonal antibody against CD154 prevents acute renal allograft rejection in nonhuman primates.” Nat Med 5, no. 6 (June 1999): 686–93. https://doi.org/10.1038/9536.
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  - Knechtle, S. J. “Ureteroneocystostomy for renal transplantation.” J Am Coll Surg 188, no. 6 (June 1999): 707–9. https://doi.org/10.1016/s1072-7515(99)00046-0.
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  - Knechtle, Stuart J., John H. Fechner, Yinchen Dong, Xuening Hong, Masahiro Tsuchida, Kevin Brunner, David Neville, and Majed Hamawy. “CENTRAL TOLERANCE IS NOTA SIGNIFICANT MECHANISM FOR PROLONGED ALLOGRAFT SURVIVAL IN ANTI-CD3 IMMUNOTOXIN TREATED MONKEYS.” Transplantation 67, no. 9 (May 1999): S557–S557. https://doi.org/10.1097/00007890-199905150-00084.
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  - Rayhill, Stephen C., Anthony M. D’Alessandro, Alexandru I. Musat, Dennis M. Heisey, Stuart J. Knechtle, Jon S. Odorico, John D. Pirsch, Hans W. Sollinger, and Munci Kalayoglu. “PEDIATRIC RECIPIENTS OF LIVERS FROM FEMALE DONORS ARE AT GREATER RISK FOR HEPATIC ARTERY THROMBOSIS (HAT).” Transplantation 67, no. 9 (May 1999): S635–S635. https://doi.org/10.1097/00007890-199905150-00393.
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  - Luzzio, C. C., A. J. Waclawik, C. L. Gallagher, and S. J. Knechtle. “Iliac artery pseudoaneurysm following renal transplantation presenting as lumbosacral plexopathy.” Transplantation 67, no. 7 (April 15, 1999): 1077–78. https://doi.org/10.1097/00007890-199904150-00026.
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  - Becker, Y. T., M. Groshek, B. N. Becker, B. H. Collins, J. S. Odorico, M. Hanaway, J. D. Pirsch, S. J. Knechtle, A. M. D’Alessandro, and H. W. Sollinger. “A SURVEY OF MALE SEXUAL FUNCTION FOLLOWING PANCREAS TRANSPLANTATION.” Transplantation 67, no. 7 (April 1999): S174–S174. https://doi.org/10.1097/00007890-199904150-00697.
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  - Hamawy, M. M., M. Tsuchida, E. R. Manthei, J. H. Fechner, and S. J. Knechtle. “Immunotoxin FN18-CRM9 is Superior to the Unconjugated Monoclonal Antibody (FN18) in Inducing Protein Tyrosine Phosphorylation and CD3 Internalization.” Transplantation 67, no. 7 (April 1999): S263–S263. https://doi.org/10.1097/00007890-199904150-01052.
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  - Pirsch, J. D., A. M. D’Alessandro, S. J. Knechtle, J. S. Odorico, B. N. Becker, G. E. Leverson, R. M. Hoffmann, and H. W. Sollinger. “CHANGING DONOR AND RECIPIENT DEMOGRAPHICS AFFECTS LONG-TERM RENAL ALLOGRAFT OUTCOME.” Transplantation 67, no. 7 (April 1999): S219–S219. https://doi.org/10.1097/00007890-199904150-00873.
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  - Tsuchida, M., E. R. Manthei, S. J. Knechtle, and M. M. Hamawy. “Downregulation of CD28- and T cell Antigen Receptor-Mediated T Cell Activation by Protein Kinase C-Stimulated Tyrosine Phosphatases.” Transplantation 67, no. 7 (April 1999): S130–S130. https://doi.org/10.1097/00007890-199904150-00521.
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  - Tsuchida, M., S. J. Knechtle, and M. M. Hamawy. “The Aggregation of the T Cell Costimulatory Molecule CD28 Induces Tyrosine Phosphorylation of the Protein Tyrosine Kinase Pyk2.” Transplantation 67, no. 7 (April 1999): S229–S229. https://doi.org/10.1097/00007890-199904150-00914.
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  - Hamawy, M. M., M. Tsuchida, E. Manthei, J. H. Fechner, and S. J. Knechtle. “Toxin conjugation to anti-CD3 MAB FN18 potentiates MAB-induced protein tyrosine phosphorylation and CD3 internalization.” Faseb Journal 13, no. 5 (March 15, 1999): A1129–A1129.
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  - Tsuchida, M., E. Manthei, S. J. Knechtle, and M. M. Hamawy. “Protein kinase C-activated tyrosine phosphatases downregulate CD28-and CD3-induced protein tyrosine phosphorylation.” Faseb Journal 13, no. 5 (March 15, 1999): A945–A945.
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  - Tsuchida, M., S. J. Knechtle, and M. M. Hamawy. “CD28 ligation induces tyrosine phosphorylation of Pyk2 but not Fak in Jurkat T cells.” J Biol Chem 274, no. 10 (March 5, 1999): 6735–40. https://doi.org/10.1074/jbc.274.10.6735.
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  - Hamawy, M. M., M. Tsuchida, J. H. Fechner, E. Manthei, and S. J. Knechtle. “Involvement of protein tyrosine phosphorylation in immunotoxin effects on T lymphocytes.” Transplant Proc 31, no. 1–2 (February 1999): 785. https://doi.org/10.1016/s0041-1345(98)01766-7.
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  - Knechtle, S. J., and L. F. Rikkers. “Current management of esophageal variceal bleeding.” Adv Surg 33 (1999): 439–58.
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  - Odorico, J. S., G. E. Leverson, Y. T. Becker, J. D. Pirsch, S. J. Knechtle, A. M. D’Alessandro, and H. W. Sollinger. “Pancreas transplantation at the University of Wisconsin.” Clin Transpl, 1999, 199–210.
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  - Scherer, M. N., C. Graeb, S. J. Knechtle, K. W. Jauch, and E. K. Geissler. “Use of a soluble RT1A(a)/IgG chimeric molecule to prevent the cytotoxic effects of preformed anti-donor antibodies.” Langenbecks Archives of Surgery, January 1, 1999, 423–26.
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  - Odorico, J. S., J. D. Pirsch, S. J. Knechtle, A. M. D’Alessandro, and H. W. Sollinger. “A study comparing mycophenolate mofetil to azathioprine in simultaneous pancreas-kidney transplantation.” Transplantation 66, no. 12 (December 27, 1998): 1751–59. https://doi.org/10.1097/00007890-199812270-00032.
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  - Pirsch, J. D., J. S. Odorico, A. M. D’Alessandro, S. J. Knechtle, B. N. Becker, and H. W. Sollinger. “Posttransplant infection in enteric versus bladder-drained simultaneous pancreas-kidney transplant recipients.” Transplantation 66, no. 12 (December 27, 1998): 1746–50. https://doi.org/10.1097/00007890-199812270-00031.
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  - Odorico, J. S., M. N. Hakim, Y. T. Becker, W. Van der Werf, A. Musat, S. J. Knechtle, A. M. D’Alessandro, and M. Kalayoglu. “Liver transplantation as definitive therapy for complications after arterial embolization for hepatic manifestations of hereditary hemorrhagic telangiectasia.” Liver Transpl Surg 4, no. 6 (November 1998): 483–90. https://doi.org/10.1002/lt.500040609.
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  - D’Alessandro, A. M., J. D. Pirsch, S. J. Knechtle, J. S. Odorico, W. J. Van der Werf, B. H. Collins, Y. T. Becker, M. Kalayoglu, M. J. Armbrust, and H. W. Sollinger. “Living unrelated renal donation: the University of Wisconsin experience.” Surgery 124, no. 4 (October 1998): 604–10. https://doi.org/10.1067/msy.1998.91482.
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  - Hamawy, M. M., and S. J. Knechtle. “Strategies for tolerance induction in nonhuman primates.” Curr Opin Immunol 10, no. 5 (October 1998): 513–17. https://doi.org/10.1016/s0952-7915(98)80216-1.
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  - Sollinger, H. W., J. S. Odorico, S. J. Knechtle, A. M. D’Alessandro, M. Kalayoglu, and J. D. Pirsch. “Experience with 500 simultaneous pancreas-kidney transplants.” Ann Surg 228, no. 3 (September 1998): 284–96. https://doi.org/10.1097/00000658-199809000-00002.
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  - Zhai, Y., X. Hong, J. Wang, J. H. Fechner, R. E. Goodman, M. C. Johnson, and S. J. Knechtle. “Modulation of alloimmunity to major histocompatibility complex class I by cotransfer of cytokine genes in vivo.” Transpl Immunol 6, no. 3 (September 1998): 169–75. https://doi.org/10.1016/s0966-3274(98)80042-7.
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  - Knechtle, S. J., J. H. Fechner, S. Stavrou, D. M. Neville, Y. Dong, X. Hong, M. Tsuchida, and M. M. Hamawy. “Reversal of acute allograft rejection using immunotoxin.” Transplant Proc 30, no. 5 (August 1998): 2150–51. https://doi.org/10.1016/s0041-1345(98)00569-7.
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  - Knechtle, S. J., J. H. Fechner, Y. Dong, S. Stavrou, D. M. Neville, T. Oberley, P. Buckley, et al. “Primate renal transplants using immunotoxin.” Surgery 124, no. 2 (August 1998): 438–46.
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  - Armstrong, N., P. Buckley, T. Oberley, J. Fechner, Y. Dong, X. Hong, A. Kirk, D. Neville, and S. Knechtle. “Analysis of primate renal allografts after T-cell depletion with anti-CD3-CRM9.” Transplantation 66, no. 1 (July 15, 1998): 5–13. https://doi.org/10.1097/00007890-199807150-00002.
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  - Gaber, A. O., M. R. First, R. J. Tesi, R. S. Gaston, R. Mendez, L. L. Mulloy, J. A. Light, et al. “Results of the double-blind, randomized, multicenter, phase III clinical trial of Thymoglobulin versus Atgam in the treatment of acute graft rejection episodes after renal transplantation.” Transplantation 66, no. 1 (July 15, 1998): 29–37. https://doi.org/10.1097/00007890-199807150-00005.
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  - Graeb, C., M. N. Scherer, S. J. Knechtle, and E. K. Geissler. “Immunologic suppression mediated by genetically modified hepatocytes expressing secreted allo-MHC class I molecules.” Hum Immunol 59, no. 7 (July 1998): 415–25. https://doi.org/10.1016/s0198-8859(98)00037-8.
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  - Knechtle, S. J. “Rejection of the liver transplant.” Semin Gastrointest Dis 9, no. 3 (July 1998): 126–35.
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  - Zhai, Y., and S. Knechtle. “Two distinct forms of soluble MHC class I molecules synthesized by different mechanisms in normal rat cells in vitro.” Hum Immunol 59, no. 7 (July 1998): 404–14. https://doi.org/10.1016/s0198-8859(98)00039-1.
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  - Odorico, J. S., D. M. Heisey, B. J. Voss, D. S. Steiner, S. J. Knechtle, A. M. D’Alessandro, R. M. Hoffmann, and H. W. Sollinger. “Donor factors affecting outcome after pancreas transplantation.” Transplant Proc 30, no. 2 (March 1998): 276–77. https://doi.org/10.1016/s0041-1345(97)01263-3.
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  - Odorico, J. S., S. C. Rayhill, D. M. Heisey, S. J. Knechtle, A. M. D’Alessandro, J. D. Pirsch, and H. W. Sollinger. “Immunologic risks of combined kidney-pancreas transplantation.” Transplant Proc 30, no. 2 (March 1998): 249–50. https://doi.org/10.1016/s0041-1345(97)01246-3.
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  - Van der Werf, W. J., J. S. Odorico, A. M. D’Alessandro, S. J. Knechtle, J. D. Pirsch, M. Kalayoglu, and H. W. Sollinger. “Enteric conversion of bladder-drained pancreas allografts: experience in 95 patients.” Transplant Proc 30, no. 2 (March 1998): 441–42. https://doi.org/10.1016/s0041-1345(97)01347-x.
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  - Van der Werf, W. J., A. M. D’Alessandro, R. M. Hoffmann, and S. J. Knechtle. “Procurement, preservation, and transport of cadaver kidneys.” Surg Clin North Am 78, no. 1 (February 1998): 41–54. https://doi.org/10.1016/s0039-6109(05)70633-2.
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  - Van der Werf, W. J., A. M. D’Alessandro, S. J. Knechtle, G. Pilli, R. M. Hoffmann, R. H. Judd, J. S. Odorico, et al. “Infant pediatric liver transplantation results equal those for older pediatric patients.” J Pediatr Surg 33, no. 1 (January 1998): 20–23. https://doi.org/10.1016/s0022-3468(98)90353-0.
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  - Zhang, Guofeng, Daniel Vargo, Vladimir Budker, Nicholas Armstrong, Stuart Knechtle, and Jon A. Wolff. “Expression of Naked Plasmid DNA Injected into the Afferent and Efferent Vessels of Rodent and Dog Livers.” Human Gene Therapy 8, no. 15 (October 10, 1997): 1763–72. https://doi.org/10.1089/hum.1997.8.15-1763.
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  - Knechtle, Stuart J. “Immunotoxins in organ transplantation.” Current Opinion in Organ Transplantation 2, no. 1 (October 1997): 97–97. https://doi.org/10.1097/00075200-199710000-00017.
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  - Kirk, A. D., D. M. Harlan, N. N. Armstrong, T. A. Davis, Y. Dong, G. S. Gray, X. Hong, D. Thomas, J. H. Fechner, and S. J. Knechtle. “CTLA4-Ig and anti-CD40 ligand prevent renal allograft rejection in primates.” Proc Natl Acad Sci U S A 94, no. 16 (August 5, 1997): 8789–94. https://doi.org/10.1073/pnas.94.16.8789.
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  - Knechtle, S. J., J. Wang, C. Graeb, Y. Zhai, X. Hong, J. H. Fechner, and E. K. Geissler. “Direct MHC class I complementary DNA transfer to thymus induces donor-specific unresponsiveness, which involves multiple immunologic mechanisms.” J Immunol 159, no. 1 (July 1, 1997): 152–58.
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  - Knechtle, S. J., J. A. Babalola, A. M. D’Alessandro, J. D. Pirsch, and M. Kalayoglu. “Clostridial infection of a liver transplant treated with retransplantation.” Clin Transplant 11, no. 3 (June 1997): 206–8.
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  - Fechner, J. H., D. J. Vargo, E. K. Geissler, C. Graeb, J. Wang, M. J. Hanaway, D. I. Watkins, M. Piekarczyk, D. M. Neville, and S. J. Knechtle. “Split tolerance induced by immunotoxin in a rhesus kidney allograft model.” Transplantation 63, no. 9 (May 15, 1997): 1339–45. https://doi.org/10.1097/00007890-199705150-00023.
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  - Fechner, J. H., D. J. Vargo, E. K. Geissler, J. Wang, D. M. Neville, and S. J. Knechtle. “Mechanisms of tolerance induced by an immunotoxin against CD3 epsilon in a rhesus kidney allograft model.” Transplant Proc 29, no. 1–2 (February 1997): 1158. https://doi.org/10.1016/s0041-1345(96)00503-9.
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  - Sasaki, T. M., J. D. Pirsch, A. M. D’Alessandro, S. J. Knechtle, M. Kalayoglu, G. R. Hafez, and H. W. Sollinger. “Increased beta 2-microglobulin (B2M) is useful in the detection of post-transplant lymphoproliferative disease (PTLD).” Clin Transplant 11, no. 1 (February 1997): 29–33.
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  - Knechtle, S. J., D. Vargo, J. Fechner, Y. Zhai, J. Wang, M. J. Hanaway, J. Scharff, et al. “FN18-CRM9 immunotoxin promotes tolerance in primate renal allografts.” Transplantation 63, no. 1 (January 15, 1997): 1–6. https://doi.org/10.1097/00007890-199701150-00002.
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  - Knapp, L. A., L. F. Cadavid, M. E. Eberle, S. J. Knechtle, R. E. Bontrop, and D. I. Watkins. “Identification of new mamu-DRB alleles using DGGE and direct sequencing.” Immunogenetics 45, no. 3 (1997): 171–79. https://doi.org/10.1007/s002510050186.
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  - Knechtle, S. J., and L. F. Rikkers. “Emergency portacaval shunts: is Orloff correct?” Hpb Surg 10, no. 4 (1997): 253–55. https://doi.org/10.1155/1997/80586.
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  - Odorico, J. S., Y. T. Becker, W. Van der Werf, B. Collins, A. M. D’Alessandro, S. J. Knechtle, J. D. Pirsch, and H. W. Sollinger. “Advances in pancreas transplantation: the University of Wisconsin experience.” Clin Transpl, 1997, 157–66.
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  - Wrenger, E., J. D. Pirsch, C. B. Cangro, A. M. D’Alessandro, S. J. Knechtle, M. Kalayoglu, and H. W. Sollinger. “Single-center experience with renal transplantation in patients with Wegener's granulomatosis.” Transpl Int 10, no. 2 (1997): 152–56. https://doi.org/10.1007/s001470050031.
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  - Kirk, A. D., D. M. Heisey, A. M. D’Alessandro, S. J. Knechtle, J. S. Odorico, S. C. Rayhill, H. W. Sollinger, and J. D. Pirsch. “Clinical hepatitis after transplantation of hepatitis C virus-positive kidneys: HLA-DR3 as a risk factor for the development of posttransplant hepatitis.” Transplantation 62, no. 12 (December 27, 1996): 1758–62. https://doi.org/10.1097/00007890-199612270-00011.
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  - Kalker, A. J., J. D. Pirsch, D. Heisey, H. W. Sollinger, F. O. Belzer, S. J. Knechtle, and A. M. D’Alessandro. “Foot problems in the diabetic transplant recipient.” Clin Transplant 10, no. 6 Pt 1 (December 1996): 503–10.
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  - Knechtle, S. J. “Gene therapy and transplantation--a brief review.” Transplant Proc 28, no. 6 Suppl 1 (December 1996): 19–23.
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  - Knechtle, S. J., Y. Zhai, and J. Fechner. “Gene therapy in transplantation.” Transpl Immunol 4, no. 4 (December 1996): 257–64. https://doi.org/10.1016/s0966-3274(96)80045-1.
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  - Wang, J., Y. Ma, and S. J. Knechtle. “Adenovirus-mediated gene transfer into rat cardiac allografts (vol 61, pg 1726, 1996).” Transplantation 62, no. 7 (October 15, 1996): 1038–1038.
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  - D’Alessandro, A. M., M. Kalayoglu, S. J. Knechtle, and H. W. Sollinger. “Intestinal transplantation: the University of Wisconsin experience.” Transplant Proc 28, no. 5 (October 1996): 2740–41.
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  - Knechtle, S. J., D. M. Heisey, J. D. Pirsch, A. M. D’Alessandro, M. Kalayoglu, and H. W. Sollinger. “Impact of improving immunosuppressive treatment on outcome in cadaveric kidney transplantation.” Surgery 120, no. 4 (October 1996): 719–24. https://doi.org/10.1016/s0039-6060(96)80022-5.
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  - Reilly, J. M., B. G. Rubin, R. W. Thompson, B. T. Allen, M. W. Flye, C. B. Anderson, and G. A. Sicard. “Revascularization of the solitary kidney: a challenging problem in a high risk population.” Surgery 120, no. 4 (October 1996): 732–36. https://doi.org/10.1016/s0039-6060(96)80024-9.
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  - Budker, V., G. Zhang, S. Knechtle, and J. A. Wolff. “Naked DNA delivered intraportally expresses efficiently in hepatocytes.” Gene Ther 3, no. 7 (July 1996): 593–98.
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  - Wang, J., Y. Ma, and S. J. Knechtle. “Adenovirus-mediated gene transfer into rat cardiac allografts. Comparison of direct injection and perfusion.” Transplantation 61, no. 12 (June 27, 1996): 1726–29. https://doi.org/10.1097/00007890-199606270-00011.
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  - Pirsch, J. D., R. J. Ploeg, S. Gange, A. M. D’Alessandro, S. J. Knechtle, H. W. Sollinger, M. Kalayoglu, and F. O. Belzer. “Determinants of graft survival after renal transplantation.” Transplantation 61, no. 11 (June 15, 1996): 1581–86. https://doi.org/10.1097/00007890-199606150-00006.
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  - Kalayoglu, M., A. M. D’Alessandro, S. J. Knechtle, R. M. Hoffmann, J. D. Pirsch, R. H. Judd, M. Armbrust, et al. “Preliminary experience with split liver transplantation.” J Am Coll Surg 182, no. 5 (May 1996): 381–87.
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  - Hanaway, M. J., E. K. Geissler, J. Wang, J. H. Fechner, R. Buelow, and S. J. Knechtle. “Immunosuppressive effects of an HLA class I-derived peptide in a rat cardiac allograft model.” Transplantation 61, no. 8 (April 27, 1996): 1222–28. https://doi.org/10.1097/00007890-199604270-00018.
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  - Noyes, W. R., R. Rodriguez, S. J. Knechtle, J. D. Pirsch, H. W. Sollinger, A. M. D’Alessandro, R. Chappell, F. O. Belzer, and T. J. Kinsella. “Radiation therapy for renal transplant rejection refractory to pulse steroids and OKT3.” Int J Radiat Oncol Biol Phys 34, no. 5 (March 15, 1996): 1055–59. https://doi.org/10.1016/0360-3016(95)02159-0.
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  - Lochhead, K. M., J. D. Pirsch, A. M. D’Alessandro, S. J. Knechtle, M. Kalayoglu, H. W. Sollinger, and F. O. Belzer. “Risk factors for renal allograft loss in patients with systemic lupus erythematosus.” Kidney Int 49, no. 2 (February 1996): 512–17. https://doi.org/10.1038/ki.1996.73.
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  - Odorico, J. S., S. J. Knechtle, S. C. Rayhill, J. D. Pirsch, A. M. D’Alessandro, F. O. Belzer, and H. W. Sollinger. “The influence of native nephrectomy on the incidence of recurrent disease following renal transplantation for primary glomerulonephritis.” Transplantation 61, no. 2 (January 27, 1996): 228–34. https://doi.org/10.1097/00007890-199601270-00012.
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  - Rayhill, S. C., J. S. Odorico, D. M. Heisey, M. A. Wilson, J. D. Pirsch, A. M. D’Alessandro, S. J. Knechtle, D. E. Eckhoff, F. O. Belzer, and H. W. Sollinger. “Clinical and laboratory features of pancreatic transplant bladder leaks.” Transplant Proc 27, no. 6 (December 1995): 3141–42.
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  - Rayhill, S. C., J. S. Odorico, D. M. Heisey, M. A. Wilson, J. D. Pirsch, A. M. D’Alessandro, S. J. Knechtle, F. O. Belzer, D. E. Eckhoff, and H. W. Sollinger. “A comparison of the sensitivities of contrast and isotope voiding cystourethrograms for the detection of pancreas transplant bladder leaks.” Transplant Proc 27, no. 6 (December 1995): 3143–44.
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  - Eckhoff, D. E., J. D. Pirsch, A. M. D’Alessandro, S. J. Knechtle, C. J. Young, S. R. Geffner, F. O. Belzer, and M. Kalayoglu. “Pretransplant status and patient survival following liver transplantation.” Transplantation 60, no. 9 (November 15, 1995): 920–25.
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  - Knechtle, S. J., A. M. D’Alessandro, B. A. Harms, J. D. Pirsch, F. O. Belzer, and M. Kalayoglu. “Relationships between sclerosing cholangitis, inflammatory bowel disease, and cancer in patients undergoing liver transplantation.” Surgery 118, no. 4 (October 1995): 615–19. https://doi.org/10.1016/s0039-6060(05)80026-1.
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  - D’Alessandro, A. M., H. W. Sollinger, S. J. Knechtle, M. Kalayoglu, W. A. Kisken, D. T. Uehling, T. D. Moon, E. M. Messing, R. C. Bruskewitz, and J. D. Pirsch. “Living related and unrelated donors for kidney transplantation. A 28-year experience.” Ann Surg 222, no. 3 (September 1995): 353–62. https://doi.org/10.1097/00000658-199509000-00012.
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  - D’Alessandro, A. M., R. M. Hoffmann, S. J. Knechtle, D. E. Eckhoff, R. B. Love, M. Kalayoglu, H. W. Sollinger, and F. O. Belzer. “Successful extrarenal transplantation from non-heart-beating donors.” Transplantation 59, no. 7 (April 15, 1995): 977–82. https://doi.org/10.1097/00007890-199504150-00009.
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  - Pirsch, J. D., M. J. Armbrust, S. J. Knechtle, A. M. D’Alessandro, H. W. Sollinger, D. M. Heisey, and F. O. Belzer. “Obesity as a risk factor following renal transplantation.” Transplantation 59, no. 4 (February 27, 1995): 631–33.
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  - D’Alessandro, A. M., R. M. Hoffmann, S. J. Knechtle, D. E. Eckhoff, R. B. Love, M. Kalayoglu, H. W. Sollinger, and F. O. Belzer. “Controlled non-heart-beating donors: a potential source of extrarenal organs.” Transplant Proc 27, no. 1 (February 1995): 707–9.
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  - Rayhill, S. C., A. D. Kirk, J. S. Odorico, D. M. Heisey, C. B. Cangro, J. D. Pirsch, A. M. D’Alessandro, S. J. Knechtle, and H. W. Sollinger. “Simultaneous pancreas-kidney transplantation at the University of Wisconsin.” Clin Transpl, 1995, 261–69.
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  - Knechtle, S. J., M. Kalayoglu, A. M. D’Alessandro, J. D. Pirsch, M. J. Armbrust, I. A. Sproat, M. M. Wojtowycz, J. C. McDermott, A. B. Crummy, and F. O. Belzer. “Portal hypertension: surgical management in the 1990s.” Surgery 116, no. 4 (October 1994): 687–93.
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  - Eckhoff, D. E., A. M. D’Alessandro, S. J. Knechtle, J. D. Pirsch, R. J. Ploeg, R. H. Judd, F. O. Belzer, and M. Kalayoglu. “100 consecutive liver transplants in infants and children: an 8-year experience.” J Pediatr Surg 29, no. 8 (August 1994): 1135–39. https://doi.org/10.1016/0022-3468(94)90295-x.
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  - DeVito-Haynes, L. D., E. Jankowska-Gan, H. W. Sollinger, S. J. Knechtle, and W. J. Burlingham. “Monitoring of kidney and simultaneous pancreas-kidney transplantation rejection by release of donor-specific, soluble HLA class I.” Hum Immunol 40, no. 3 (July 1994): 191–201. https://doi.org/10.1016/0198-8859(94)90069-8.
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  - Wang, J., E. K. Geissler, J. H. Fechner, W. J. Burlingham, and S. J. Knechtle. “Use of donor serum to prevent passive transfer of hyperacute rejection.” J Surg Res 57, no. 1 (July 1994): 150–55. https://doi.org/10.1006/jsre.1994.1123.
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  - Knechtle, S. J., J. Wang, S. Jiao, E. K. Geissler, R. Sumimoto, and J. Wolff. “Induction of specific tolerance by intrathymic injection of recipient muscle cells transfected with donor class I major histocompatibility complex.” Transplantation 57, no. 7 (April 15, 1994): 990–96.
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  - Belzer, F. O., R. J. Ploeg, S. J. Knechtle, A. M. D’Alessandro, J. D. Pirsch, M. M. Kalayoglu, and H. W. Sollinger. “Clinical pancreas preservation and transplantation.” Transplant Proc 26, no. 2 (April 1994): 550–51.
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  - Eckhoff, D. E., R. J. Ploeg, M. A. Wilson, A. M. D’Alessandro, S. J. Knechtle, J. D. Pirsch, F. O. Belzer, and H. W. Sollinger. “Efficacy of 99mTc voiding cystourethrogram for detection of duodenal leaks after pancreas transplantation.” Transplant Proc 26, no. 2 (April 1994): 462–63.
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  - Ploeg, R. J., A. M. D’Alessandro, M. Groshek, S. J. Gange, S. J. Knechtle, M. D. Stegall, D. E. Eckhoff, J. D. Pirsch, H. W. Sollinger, and F. O. Belzer. “Efficacy of human anodal trypsinogen for detection of rejection in clinical pancreas transplantation.” Transplant Proc 26, no. 2 (April 1994): 531–33.
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  - Ploeg, R. J., D. E. Eckhoff, A. M. D’Alessandro, M. D. Stegall, S. J. Knechtle, J. D. Pirsch, H. W. Sollinger, and F. O. Belzer. “Urological complications and enteric conversion after pancreas transplantation with bladder drainage.” Transplant Proc 26, no. 2 (April 1994): 458–59.
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  - Knechtle, S. J., A. M. D’Alessandro, H. W. Sollinger, J. D. Pirsch, A. L. Friedman, M. C. Chobanian, and F. O. Belzer. “Changing spectrum of pediatric renal transplantation.” Transplant Proc 26, no. 1 (February 1994): 23.
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  - Geissler, E. K., J. Wang, J. H. Fechner, W. J. Burlingham, and S. J. Knechtle. “Immunity to MHC class I antigen after direct DNA transfer into skeletal muscle.” J Immunol 152, no. 2 (January 15, 1994): 413–21.
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  - Geffner, S. R., A. M. D’Alessandro, M. Kalayoglu, S. J. Knechtle, J. D. Pirsch, F. O. Belzer, and H. W. Sollinger. “Living-unrelated renal donor transplantation: the UNOS experience, 1987-1991. United Network for Organ Sharing.” Clin Transpl, 1994, 197–201.
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  - Ploeg, R. J., A. M. D’Alessandro, M. Groshek, S. J. Gange, S. J. Knechtle, M. D. Stegall, D. E. Eckhoff, J. D. Pirsch, H. W. Sollinger, and F. O. Belzer. “Clinical experience with human anodal trypsinogen (HAT) for detection of pancreatic allograft rejection.” Transpl Int 7 Suppl 1 (1994): S426–31. https://doi.org/10.1111/j.1432-2277.1994.tb01411.x.
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  - Ploeg, R. J., A. M. D’Alessandro, R. M. Hoffmann, D. Eckhoff, R. Isaacs, S. J. Knechtle, J. D. Pirsch, M. D. Stegall, M. Kalayoglu, and F. O. Belzer. “Impact of donor factors and preservation on function and survival after liver transplantation.” Transplant Proc 25, no. 6 (December 1993): 3031–33.
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  - Kalayoglu, M., A. M. D’Alessandro, S. J. Knechtle, D. E. Eckhoff, J. D. Pirsch, R. Judd, H. W. Sollinger, R. M. Hoffmann, and F. O. Belzer. “Long-term results of liver transplantation for biliary atresia.” Surgery 114, no. 4 (October 1993): 711–17.
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  - Knechtle, S. J., M. Kalayolu, A. M. D’Alessandro, B. Mason, J. D. Pirsch, H. W. Sollinger, D. C. Steen, and F. O. Belzer. “Histocompatibility and liver transplantation.” Surgery 114, no. 4 (October 1993): 667–71.
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  - Sollinger, H. W., E. M. Messing, D. E. Eckhoff, J. D. Pirsch, A. M. D’Alessandro, M. Kalayoglu, S. J. Knechtle, D. Hickey, and F. O. Belzer. “Urological complications in 210 consecutive simultaneous pancreas-kidney transplants with bladder drainage.” Ann Surg 218, no. 4 (October 1993): 561–68. https://doi.org/10.1097/00000658-199310000-00016.
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  - Sollinger, H. W., R. J. Ploeg, D. E. Eckhoff, M. D. Stegall, R. Isaacs, J. D. Pirsch, A. M. D’Alessandro, S. J. Knechtle, M. Kalayoglu, and F. O. Belzer. “Two hundred consecutive simultaneous pancreas-kidney transplants with bladder drainage.” Surgery 114, no. 4 (October 1993): 736–43.
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  - Kalayoglu, M., A. M. D’Alessandro, S. J. Knechtle, H. W. Sollinger, J. D. Pirsch, R. M. Hoffmann, and F. O. Belzer. “State of the art of liver transplantation in the USA.” Transplantation Proceedings 25, no. 4 SUPPL. (August 21, 1993): 47.
  - Kalayoglu, M., A. M. D’Alessandro, S. J. Knechtle, R. M. Hoffmann, H. W. Sollinger, and F. O. Belzer. “Surgical refinements in liver transplantation.” Transplantation Proceedings 25, no. 4 SUPPL. (August 21, 1993): 48–49.
  - Pirsch, J. D., A. M. D’Alessandro, S. J. Knechtle, M. Kalayoglu, H. W. Sollinger, and F. O. Belzer. “Renal transplantation in the cyclosporine era.” Transplantation Proceedings 25, no. 4 SUPPL. (August 21, 1993): 15–16.
  - Kalayoglu, M., A. M. D’Alessandro, S. J. Knechtle, H. W. Sollinger, J. D. Pirsch, R. M. Hoffmann, and F. O. Belzer. “State of the art of liver transplantation in the USA.” Transplant Proc 25, no. 4 Suppl 3 (August 1993): 47.
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  - Kalayoglu, M., A. M. D’Alessandro, S. J. Knechtle, R. M. Hoffmann, H. W. Sollinger, and F. O. Belzer. “Surgical refinements in liver transplantation.” Transplant Proc 25, no. 4 Suppl 3 (August 1993): 48–49.
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  - Pirsch, J. D., A. M. D’Alessandro, S. J. Knechtle, H. W. Sollinger, F. O. Belzer, and M. Kalayoglu. “Effect of cyclosporine on renal function in survivors of liver transplantation after 1 year.” Transplant Proc 25, no. 4 Suppl 3 (August 1993): 13–14.
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  - Pirsch, J. D., A. M. D’Alessandro, S. J. Knechtle, M. Kalayoglu, F. O. Belzer, and H. W. Sollinger. “Simultaneous kidney-pancreas transplantation at the University of Wisconsin.” Transplant Proc 25, no. 4 Suppl 3 (August 1993): 33–34.
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  - Pirsch, J. D., A. M. D’Alessandro, S. J. Knechtle, M. Kalayoglu, H. W. Sollinger, and F. O. Belzer. “Renal transplantation in the cyclosporine era.” Transplant Proc 25, no. 4 Suppl 3 (August 1993): 15–16.
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  - Burlingham, W. J., J. H. Fechner, L. D. DeVito, H. W. Sollinger, S. J. Knechtle, and A. P. Grailer. “Human interleukin-2 and lymphoproliferative (T-helper cell) responses to soluble HLA class I antigens in vitro: I. Specificity for polymorphic domains.” Tissue Antigens 42, no. 1 (July 1993): 35–38. https://doi.org/10.1111/j.1399-0039.1993.tb02163.x.
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  - D’Alessandro, A. M., R. J. Ploeg, S. J. Knechtle, J. D. Pirsch, M. D. Stegall, R. Hoffmann, H. W. Sollinger, F. O. Belzer, and M. Kalayoglu. “Retransplantation of the liver--a seven-year experience.” Transplantation 55, no. 5 (May 1993): 1083–87. https://doi.org/10.1097/00007890-199305000-00028.
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  - Belzer, F. O., J. H. Southard, A. M. D’Alessandro, S. J. Knechtle, H. W. Sollinger, and M. Kalayoglu. “Update on preservation of liver grafts.” Transplant Proc 25, no. 2 (April 1993): 2010–11.
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  - Knechtle, S. J., M. F. Fleming, K. L. Barry, D. Steen, J. D. Pirsch, A. M. D’Alessandro, M. Kalayoglu, and F. O. Belzer. “Liver transplantation in alcoholics: assessment of psychological health and work activity.” Transplant Proc 25, no. 2 (April 1993): 1916–18.
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  - Ploeg, R. J., A. M. D’Alessandro, M. D. Stegall, M. Wojtowycz, I. A. Sproat, S. J. Knechtle, J. D. Pirsch, H. W. Sollinger, F. O. Belzer, and M. Kalayoglu. “Effect of surgical and spontaneous portasystemic shunts on liver transplantation.” Transplant Proc 25, no. 2 (April 1993): 1946–48.
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  - Ploeg, R. J., A. M. D’Alessandro, S. J. Knechtle, M. D. Stegall, J. D. Pirsch, R. M. Hoffmann, T. Sasaki, H. W. Sollinger, F. O. Belzer, and M. Kalayoglu. “Risk factors for primary dysfunction after liver transplantation--a multivariate analysis.” Transplantation 55, no. 4 (April 1993): 807–13. https://doi.org/10.1097/00007890-199304000-00024.
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  - Knechtle, S. J., M. Kalayoglu, A. M. D’Alessandro, J. D. Pirsch, R. M. Hoffmann, H. W. Sollinger, and F. O. Belzer. “Should abdominal cluster transplantation be abandoned?” Transplant Proc 25, no. 1 Pt 2 (February 1993): 1361–63.
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  - Pirsch, J. D., A. M. D’Alessandro, E. B. Roecker, S. J. Knechtle, A. Reed, H. W. Sollinger, M. Kalayoglu, and F. O. Belzer. “A controlled, double-blind, randomized trial of verapamil and cyclosporine in cadaver renal transplant patients.” Am J Kidney Dis 21, no. 2 (February 1993): 189–95. https://doi.org/10.1016/s0272-6386(12)81092-4.
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  - Ploeg, R. J., A. M. D’Alessandro, S. J. Knechtle, M. D. Stegall, J. D. Pirsch, R. M. Hoffmann, T. Sasaki, H. W. Sollinger, F. O. Belzer, and M. Kalayoglu. “Malfunction of the liver after transplantation: an analysis of potential risk factors.” Transplant Proc 25, no. 1 Pt 2 (February 1993): 1659–61.
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  - Ploeg, R. J., J. D. Pirsch, M. D. Stegall, M. J. Armbrust, D. F. Lorentzen, A. M. D’Alessandro, S. J. Knechtle, H. W. Sollinger, M. Kalayoglu, and F. O. Belzer. “Living unrelated kidney donation: an underutilized resource?” Transplant Proc 25, no. 1 Pt 2 (February 1993): 1532–34.
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  - Sasaki, T., J. D. Pirsch, R. J. Ploeg, M. D. Stegall, A. M. D’Alessandro, S. J. Knechtle, F. O. Belzer, and H. W. Sollinger. “Effects of DR mismatch on long-term graft survival in simultaneous kidney-pancreas transplantation.” Transplant Proc 25, no. 1 Pt 1 (February 1993): 237–38.
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  - Stegall, M. D., R. J. Ploeg, J. D. Pirsch, T. M. Sasaki, A. M. D’Alessandro, S. J. Knechtle, F. O. Belzer, and H. W. Sollinger. “Living-related kidney transplant or simultaneous pancreas-kidney for diabetic renal failure?” Transplant Proc 25, no. 1 Pt 1 (February 1993): 230–32.
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  - Knechtle, S. J., J. D. Pirsch, A. M. D’Alessandro, H. W. Sollinger, M. Kalayoglu, and F. O. Belzer. “Renal transplantation at the University of Wisconsin in the cyclosporine era.” Clin Transpl, 1993, 211–18.
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  - Knechtle, S. J., M. Kalayoglu, A. M. D’Alessandro, J. D. Pirsch, R. M. Hoffmann, H. W. Sollinger, and F. O. Belzer. “Should abdominal cluster transplantation be abandoned?” Transplantation Proceedings 25, no. 1 SUPPL. 1 (January 1, 1993): 1361–63.
  - Pirsch, J. D., A. M. D’Alessandro, S. J. Knechtle, M. Kalayoglu, F. O. Belzer, and H. W. Sollinger. “Simultaneous kidney-pancreas transplantation at the University of Wisconsin.” Transplantation Proceedings 25, no. 4 SUPPL. (January 1, 1993): 33–34.
  - Ploeg, R. J., J. D. Pirsch, M. D. Stegall, M. J. Armbrust, D. F. Lorentzen, A. M. D’Alessandro, S. J. Knechtle, H. W. Sollinger, M. Kalayoglu, and F. O. Belzer. “Living unrelated kidney donation: An underutilized resource?” Transplantation Proceedings 25, no. 1 SUPPL. 1 (January 1, 1993): 1532–34.
  - Knechtle, S. J., M. F. Fleming, K. L. Barry, D. Steen, J. D. Pirsch, G. R. Hafez, A. M. D’Alessandro, A. Reed, H. W. Sollinger, and M. Kalayoglu. “Liver transplantation for alcoholic liver disease.” Surgery 112, no. 4 (October 1992): 694–701.
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  - Sollinger, H. W., T. M. Sasaki, A. M. D’Alessandro, S. J. Knechtle, J. D. Pirsch, M. Kalayoglu, and F. O. Belzer. “Indications for enteric conversion after pancreas transplantation with bladder drainage.” Surgery 112, no. 4 (October 1992): 842–45.
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  - Belzer, F. O., A. M. D’Alessandro, R. M. Hoffmann, S. J. Knechtle, A. Reed, J. D. Pirsch, M. Kalayoglu, and H. W. Sollinger. “The use of UW solution in clinical transplantation. A 4-year experience.” Ann Surg 215, no. 6 (June 1992): 579–83. https://doi.org/10.1097/00000658-199206000-00004.
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  - Pirsch, J. D., A. M. D’Alessandro, H. W. Sollinger, S. J. Knechtle, A. Reed, M. Kalayoglu, and F. O. Belzer. “Hyperlipidemia and transplantation: etiologic factors and therapy.” J Am Soc Nephrol 2, no. 12 Suppl (June 1992): S238–42. https://doi.org/10.1681/ASN.V212s238.
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  - Knechtle, S. J., J. Wang, W. J. Burlingham, M. Beeskau, R. Subramanian, and H. W. Sollinger. “The influence of RS-61443 on antibody-mediated rejection.” Transplantation 53, no. 3 (March 1992): 699–701.
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  - Wang, J., S. Jiao, J. A. Wolff, and S. J. Knechtle. “Gene transfer and expression in rat cardiac transplants.” Transplantation 53, no. 3 (March 1992): 703–5.
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  - Pirsch, J. D., A. M. D’Alessandro, H. W. Sollinger, R. M. Hoffmann, E. Roecker, B. J. Voss, D. Lorentzen, S. J. Knechtle, A. Reed, and M. Kalayoglu. “The effect of donor age, recipient age, and HLA match on immunologic graft survival in cadaver renal transplant recipients.” Transplantation 53, no. 1 (January 1992): 55–59. https://doi.org/10.1097/00007890-199201000-00010.
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  - D’Alessandro, A. M., M. Kalayoglu, J. D. Pirsch, C. Corwith, S. J. Knechtle, A. Reed, and F. O. Belzer. “FK 506 rescue therapy for resistant rejection episodes in liver transplant recipients.” Transplant Proc 23, no. 6 (December 1991): 2987–88.
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  - Pirsch, J. D., M. Kalayoglu, A. M. D’Alessandro, S. J. Knechtle, A. Reed, H. W. Sollinger, and F. O. Belzer. “Pulmonary infiltrates and eosinophilia in an FK 506 liver transplant recipient.” Transplant Proc 23, no. 6 (December 1991): 3195–96.
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  - Sollinger, H. W., S. J. Knechtle, A. Reed, A. M. D’Alessandro, M. Kalayoglu, F. O. Belzer, and J. Pirsch. “Experience with 100 consecutive simultaneous kidney-pancreas transplants with bladder drainage.” Ann Surg 214, no. 6 (December 1991): 703–11. https://doi.org/10.1097/00000658-199112000-00010.
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  - D’Alessandro, A. M., H. W. Sollinger, M. Kalayoglu, J. D. Pirsch, A. Reed, S. J. Knechtle, and F. O. Belzer. “Indications and techniques for renal, pancreas, and liver transplantation.” Compr Ther 17, no. 11 (November 1991): 32–42.
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  - D’Alessandro, A. M., A. Reed, R. M. Hoffmann, H. W. Sollinger, M. Kalayoglu, S. J. Knechtle, J. D. Pirsch, and F. O. Belzer. “Results of combined hepatic, pancreaticoduodenal, and renal procurements.” Transplant Proc 23, no. 5 (October 1991): 2309–11.
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  - D’Alessandro, A. M., M. Kalayoglu, J. D. Pirsch, H. W. Sollinger, A. Reed, S. J. Knechtle, R. M. Hoffmann, and F. O. Belzer. “Biliary tract complications after orthotopic liver transplantation.” Transplant Proc 23, no. 3 (June 1991): 1956.
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  - Knechtle, S., A. D’Alessandro, A. Reed, H. Sollinger, J. Pirsch, F. Belzer, and M. Kalayoglu. “Liver retransplantation: the University of Wisconsin experience.” Transplant Proc 23, no. 3 (June 1991): 1955.
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  - D’Alessandro, A. M., M. Kalayoglu, H. W. Sollinger, R. M. Hoffmann, A. Reed, S. J. Knechtle, J. D. Pirsch, G. R. Hafez, D. Lorentzen, and F. O. Belzer. “The predictive value of donor liver biopsies on the development of primary nonfunction after orthotopic liver transplantation.” Transplant Proc 23, no. 1 Pt 2 (February 1991): 1536–37.
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  - Knechtle, S. J., J. D. Pirsch, M. Groshek, A. Reed, A. M. D’Alessandro, M. Kalayoglu, F. O. Belzer, and H. W. Sollinger. “OKT3 vs ALG induction therapy in combined pancreas-kidney transplantation.” Transplant Proc 23, no. 1 Pt 2 (February 1991): 1581–82.
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  - Pirsch, J. D., B. J. Voss, E. B. Roecker, D. F. Lorentzen, S. J. Knechtle, A. Reed, A. M. D’Alessandro, H. W. Sollinger, M. Kalayoglu, and F. O. Belzer. “Predictive factors for immunologic graft failure in cadaver renal transplant recipients.” Transplant Proc 23, no. 1 Pt 2 (February 1991): 1282–83.
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  - Pirsch, J. D., M. J. Armbrust, S. J. Knechtle, A. Reed, A. M. D’Alessandro, H. W. Sollinger, and F. O. Belzer. “Effect of steroid withdrawal on hypertension and cholesterol levels in living related recipients.” Transplant Proc 23, no. 1 Pt 2 (February 1991): 1363–64.
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  - Pirsch, J. D., M. Kalayoglu, A. M. D’Alessandro, B. J. Voss, M. J. Armbrust, A. Reed, S. J. Knechtle, H. W. Sollinger, and F. O. Belzer. “Orthotopic liver transplantation in patients 60 years of age and older.” Transplantation 51, no. 2 (February 1991): 431–33. https://doi.org/10.1097/00007890-199102000-00031.
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  - Pirsch, J. D., M. Kalayoglu, A. M. D’Alessandro, M. J. Armbrust, A. Reed, S. J. Knechtle, H. W. Sollinger, and F. O. Belzer. “Orthotopic liver transplantation in patients over 60 years of age.” Transplant Proc 23, no. 1 Pt 2 (February 1991): 1456–57.
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  - Reed, A., J. D. Pirsch, M. J. Armbrust, W. J. Burlingham, S. J. Knechtle, A. M. D’Alessandro, H. W. Sollinger, M. Kalayoglu, and F. O. Belzer. “A comparison of donor-specific and random transfusions in living-related renal transplantation and their effect on steroid withdrawal.” Transplant Proc 23, no. 1 Pt 2 (February 1991): 1321–22.
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  - Reed, A., J. Pirsch, M. J. Armbrust, W. J. Burlingham, S. J. Knechtle, A. M. D’Alessandro, H. W. Sollinger, D. Lorentzen, M. Kalayoglu, and F. O. Belzer. “Multivariate analysis of donor-specific versus random transfusion protocols in haploidentical living-related transplants.” Transplantation 51, no. 2 (February 1991): 382–84. https://doi.org/10.1097/00007890-199102000-00022.
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  - D’Alessandro, A. M., M. Kalayoglu, H. W. Sollinger, R. M. Hoffmann, A. Reed, S. J. Knechtle, J. D. Pirsch, G. R. Hafez, D. Lorentzen, and F. O. Belzer. “The predictive value of donor liver biopsies for the development of primary nonfunction after orthotopic liver transplantation.” Transplantation 51, no. 1 (January 1991): 157–63. https://doi.org/10.1097/00007890-199101000-00024.
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  - Reed, A., H. W. Sollinger, S. J. Knechtle, A. M. D’Alessandro, M. Kalayoglu, J. D. Pirsch, and F. O. Belzer. “Ruptured splenic artery aneurysm: An unusual late complication following pancreas transplantation.” Clinical Transplantation 5, no. 4 (January 1, 1991): 327–29.
  - Sasaki, T., J. D. Pirsch, A. M. D’Alessandro, S. J. Knechtle, M. Kalayoglu, F. O. Belzer, and H. W. Sollinger. “Simultaneous pancreas-kidney transplantation at University of Wisconsin-Madison Hospital.” Clin Transpl, 1991, 135–39.
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  - Knechtle, S. J., J. Wang, M. Beeskau, W. J. Burlingham, H. W. Sollinger, and F. O. Belzer. “Effect of RS-61443 in preventing rejection in sensitized recipients.” Surgical Forum 41 (December 1, 1990): 380–81.
  - Knechtle, S. J., and H. C. Filston. “Anomalous biliary ducts associated with duodenal atresia.” J Pediatr Surg 25, no. 12 (December 1990): 1266–69. https://doi.org/10.1016/0022-3468(90)90527-g.
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  - D’Alessandro, A. M., H. W. Sollinger, R. M. Hoffmann, M. Kalayoglu, J. S. Melzer, A. Reed, S. J. Knechtle, J. D. Pirsch, and F. O. Belzer. “Experience with combined hepatic, pancreaticoduodenal, and renal procurement with UW solution.” Transplant Proc 22, no. 4 (August 1990): 2076–77.
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  - D’Alessandro, A. M., J. D. Pirsch, J. S. Melzer, H. W. Sollinger, M. Kalayoglu, A. Reed, S. J. Knechtle, and F. O. Belzer. “Use of OKT3 in kidney, pancreas, and liver transplantation.” Transplant Proc 22, no. 4 (August 1990): 1748–49.
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  - Kalayoglu, M., A. M. D’Alessandro, H. W. Sollinger, R. M. Hoffmann, J. D. Pirsch, J. S. Melzer, A. Reed, S. J. Knechtle, and F. O. Belzer. “Experience with reduced-size liver transplantation in infants and children.” Transplant Proc 22, no. 4 (August 1990): 1489–91.
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  - Knechtle, S. J., A. M. Davidoff, and R. P. Rice. “Pneumatosis intestinalis. Surgical management and clinical outcome.” Ann Surg 212, no. 2 (August 1990): 160–65. https://doi.org/10.1097/00000658-199008000-00008.
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  - Halperin, E. C., S. J. Knechtle, R. C. Harland, Y. Yamaguchi, M. Sontag, and R. R. Bollinger. “Irradiation for xenogeneic transplantation.” Radiother Oncol 18, no. 1 (May 1990): 29–37. https://doi.org/10.1016/0167-8140(90)90020-w.
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  - Pirsch, J. D., A. M. D’Alessandro, H. W. Sollinger, B. J. Voss, S. J. Knechtle, A. Reed, M. Kalayoglu, and F. O. Belzer. “Living-unrelated renal transplantation at the University of Wisconsin.” Clin Transpl, 1990, 241–45.
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  - Knechtle, S. J., D. C. Castle, H. F. Seigler, and R. R. Bollinger. “Renal transplantation in the American black.” Transplant Proc 21, no. 6 (December 1989): 3931–33.
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  - Knechtle, S. J., Y. Yamaguchi, A. Coundouriotis, and R. R. Bollinger. “Mediation of hyperacute rejection of rat hepatic allografts by RT-1 antigens.” Transplantation 48, no. 4 (October 1989): 723–25.
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  - Knechtle, S. J., Y. Yamaguchi, R. C. Harland, A. Coundouriotis, and R. R. Bollinger. “The role of class I antigens in hyperacute rejection of hepatic allografts in rats.” Transplant Proc 21, no. 3 (June 1989): 3557.
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  - Knechtle, S. J., and R. R. Bollinger. “Perforation of the gastrointestinal tract following renal transplantation.” Transplant Proc 21, no. 1 Pt 2 (February 1989): 2143–44.
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  - D’Alessandro, A. M., D. F. Lorentzen, J. D. Pirsch, S. J. Knechtle, A. Reed, R. M. Hoffmann, M. J. Armbrust, H. W. Sollinger, M. Kalayoglu, and F. O. Belzer. “Cadaveric renal transplantation in the cyclosporine and OKT3 eras: an update of the University of Wisconsin-Madison experience.” Clin Transpl, 1989, 239–51.
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  - HARLAND, R. C., S. J. KNECHTLE, Y. YAMAGUCHI, and R. R. BOLLINGER. “ANTIBODY-TITERS AND CARDIAC ALLOGRAFT SURVIVAL IN THE SENSITIZED RAT MODEL - EFFECT OF TIME AFTER INITIAL SENSITIZATION.” Transplantation Proceedings 20, no. 1 (February 1, 1988): 839–41.
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  - Halperin, E. C., S. Knechtle, K. Abernethy, T. Saad, D. Miller, W. B. Vernon, and R. R. Bollinger. “The influence of dose and dose rate of total lymphoid irradiation in the rat cardiac allograft model.” Radiother Oncol 9, no. 4 (August 1987): 311–18. https://doi.org/10.1016/s0167-8140(87)80152-4.
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  - Knechtle, S. J., E. C. Halperin, and R. R. Bollinger. “Xenograft survival in two species combinations using total-lymphoid irradiation and cyclosporine.” Transplantation 43, no. 2 (February 1987): 173–75. https://doi.org/10.1097/00007890-198702000-00002.
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  - Knechtle, S. J., E. C. Halperin, and R. R. Bollinger. “Combined total lymphoid irradiation and cyclosporine promote xenograft survival.” Transplant Proc 19, no. 1 Pt 2 (February 1987): 1137–39.
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  - Knechtle, S. J., J. A. Wolfe, J. Burchette, F. Sanfilippo, and R. R. Bollinger. “Infiltrating cell phenotypes and patterns associated with hepatic allograft rejection or acceptance.” Transplantation 43, no. 2 (February 1987): 169–72. https://doi.org/10.1097/00007890-198702000-00001.
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  - Knechtle, S. J., K. Kempf, and R. R. Bollinger. “Peptic ulcer disease following renal transplantation.” Transplant Proc 19, no. 1 Pt 3 (February 1987): 2233–36.
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  - Knechtle, S. J., P. C. Kolbeck, S. Tsuchimoto, A. Coundouriotis, F. Sanfilippo, and R. R. Bollinger. “Humoral rejection of rat hepatic transplants by passive transfer of serum.” Transplant Proc 19, no. 1 Pt 2 (February 1987): 1072–76.
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  - Wolfe, J. A., S. J. Knechtle, J. Burchette, R. R. Bollinger, and F. Sanfilippo. “Phenotype and patterns of inflammatory cell infiltration associated with rejection or acceptance of rat liver allografts.” Transplant Proc 19, no. 1 Pt 1 (February 1987): 364–68.
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  - Cruise, J. L., S. J. Knechtle, R. R. Bollinger, C. Kuhn, and G. Michalopoulos. “α₁-Adrenergic effects and liver regeneration.” Hepatology 7, no. 6 (1987): 1189–94.
  - Knechtle, S. J., P. C. Kolbeck, S. Tsuchimoto, A. Coundouriotis, F. Sanfilippo, and R. R. Bollinger. “Hepatic transplantation into sensitized recipients. Demonstration of hyperacute rejection.” Transplantation 43, no. 1 (January 1987): 8–12. https://doi.org/10.1097/00007890-198701000-00003.
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  - Knechtle, S. J., P. Kolbeck, S. Tsuchimoto, F. Sanfilippo, and R. R. Bollinger. “Hyperacute rejection of liver transplants in rats.” Curr Surg 43, no. 4 (July 1986): 303–5.
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  - Knechtle, S. J., E. C. Halperin, T. Saad, and R. R. Bollinger. “Prolonged heart xenograft survival using combined total lymphoid irradiation and cyclosporine.” J Heart Transplant 5, no. 3 (May 1986): 254–61.
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  - Knechtle, S. J., E. C. Halperin, C. E. Murphy, T. Saad, K. Abernethy, D. Miller, and R. R. Bollinger. “The effect of cyclosporine, total lymphoid irradiation, and cobra venom factor on hyperacute rejection.” J Heart Transplant 4, no. 5 (September 1985): 541–45.
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  - Inman, R. D., P. B. Redecha, S. J. Knechtle, E. S. Schned, I. van de Rijn, and C. L. Christian. “Identification of bacterial antigens in circulating immune complexes of infective endocarditis.” J Clin Invest 70, no. 2 (August 1982): 271–80. https://doi.org/10.1172/jci110614.
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  - Kawata, Kazuhito, Masanobu Tsuda, Guo-Xiang Yang, Weici Zhang, Hajime Tanaka, Koichi Tsuneyama, Patrick Leung, et al. “Identification of Potential Cytokine Pathways for Therapeutic Intervention in Murine Primary Biliary Cirrhosis.” Plos One 8, no. 9 (n.d.): e74225–e74225. https://doi.org/10.1371/journal.pone.0074225.
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  - Kelsoe, Garnett, Shengli Song, Miriam Manook, Jean Kwun, Annette Jackson, and Stuart Knechtle. “A Novel Cell-Based Multiplex Immunoassay Platform,” n.d. https://doi.org/10.21203/rs.3.rs-464450/v1.
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  - Kesseli, Samuel J., Jared N. Gloria, Nader Abraham, Samantha E. Halpern, Greta N. Cywinska, Min Zhang, Dimitrios Moris, et al. “Point‐of‐Care Assessment of DCD Livers During Normothermic Machine Perfusion in a Nonhuman Primate Model.” Hepatology Communications, n.d. https://doi.org/10.1002/hep4.1734.
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- Book Sections
  - Ellis, M. J., B. H. Collins, B. Ezekian, and S. J. Knechtle. “Medical evaluation of the living donor.” In Kidney Transplantation - Principles and Practice, 104–14, 2019. https://doi.org/10.1016/B978-0-323-53186-3.00007-3.
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  - Patzer, R. E., R. E. Hamoda, and S. J. Knechtle. “Results of renal transplantation.” In Kidney Transplantation - Principles and Practice, 684–708, 2019. https://doi.org/10.1016/B978-0-323-53186-3.00039-5.
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  - Schroder, P. M., L. P. Marson, and S. J. Knechtle. “Early course of the patient with a kidney transplant.” In Kidney Transplantation - Principles and Practice, 198–211, 2019. https://doi.org/10.1016/B978-0-323-53186-3.00014-0.
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  - Knechtle, S. J., and J. R. Galloway. “Chapter 85-Portal hypertensive bleeding: The place of portosystemic shunting.” In Blumgart’s Surgery of the Liver, Biliary Tract and Pancreas: Sixth Edition, 2–2:1218-1230.e3, 2016. https://doi.org/10.1016/B978-0-323-34062-5.00085-6.
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  - Page, E. K., I. R. Badell, and S. J. Knechtle. “Immunosuppression in Transplantation.” In Pathobiology of Human Disease: A Dynamic Encyclopedia of Disease Mechanisms, 741–51, 2014. https://doi.org/10.1016/B978-0-12-386456-7.02214-0.
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  - Knechtle, S. J., and S. Pastan. “Early course of the patient with a kidney transplant.” In Kidney Transplantation-Principles and Practice, Seventh Edition, 204–15, 2013. https://doi.org/10.1016/B978-1-4557-4096-3.00014-3.
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  - Patzer, R. E., and S. J. Knechtle. “Results of renal transplantation.” In Kidney Transplantation-Principles and Practice, Seventh Edition, 676–97, 2013. https://doi.org/10.1016/B978-1-4557-4096-3.00039-8.
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  - Knechtle, S. J., and J. R. Galloway. “Location of portosystemic shunting.” In Blumgart’s Surgery of the Liver, Biliary Tract, and Pancreas, 2:1146–58, 2012. https://doi.org/10.1016/B978-1-4377-1454-8.00076-X.
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  - Agarwal, A., D. Bruno, and S. J. Knechtle. “The Role of Alemtuzumab in Solid Organ Transplantation.” In Immunotherapy in Transplantation: Principles and Practice, 346–61, 2012. https://doi.org/10.1002/9781444355628.ch23.
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  - Bollinger, R. R., and S. J. Knechtle. “Vascular access for dialysis, chemotherapy, and nutritional support.” In Surgery: Basic Science and Clinical Evidence: Second Edition, 1457–68, 2008. https://doi.org/10.1007/978-0-387-68113-9_69.
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  - Knechtle, S. J. “Kidney transplantation.” In Surgery: Basic Science and Clinical Evidence: Second Edition, 1759–72, 2008. https://doi.org/10.1007/978-0-387-68113-9_84.
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  - Knechtle, S. J., and J. D. Pirsch. “Early Course of the Patient with a Kidney Transplant.” In Kidney Transplantation, 210–19, 2008. https://doi.org/10.1016/B978-1-4160-3343-1.50018-9.
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  - Knechtle, S. J., and P. J. Morris. “Results of Renal Transplantation.” In Kidney Transplantation, 657–75, 2008. https://doi.org/10.1016/B978-1-4160-3343-1.50041-4.
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- Other Articles
  - Knechtle, S. J., and D. L. Sudan. “Surgical technique in transplantation: how much does it matter?” Am J Transplant, November 2015. https://doi.org/10.1111/ajt.13484.
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  - Knechtle, S. J., and A. B. Adams. “Belatacept: is there BENEFIT for liver transplantation too?” Am J Transplant, August 2014. https://doi.org/10.1111/ajt.12806.
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  - Knechtle, Stuart J., and Daniel C. Brennan. “Starting well: induction immunosuppression after organ transplantation.” Transpl Int, July 2013. https://doi.org/10.1111/tri.12124.
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  - Page, Eugenia K., Wasim A. Dar, and Stuart J. Knechtle. “Reply to Vanhove et al.” Transpl Int, April 2013. https://doi.org/10.1111/tri.12076.
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  - Kirk, A. D., S. J. Knechtle, C. P. Larsen, K. A. Newell, and T. C. Pearson. “Miles to go….” Am J Transplant, June 2011. https://doi.org/10.1111/j.1600-6143.2011.03542.x.
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  - Knechtle, S. J. “Guidance for liver transplant immunosuppression.” Am J Transplant, May 2011. https://doi.org/10.1111/j.1600-6143.2011.03488.x.
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  - Knechtle, S. J. “Seek and you will find: antibody and the liver.” Am J Transplant, March 2011. https://doi.org/10.1111/j.1600-6143.2010.03410.x.
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  - Knechtle, Stuart J., Jean Kwun, and Neal Iwakoshi. “Prevention trumps treatment of antibody-mediated transplant rejection.” J Clin Invest, April 2010. https://doi.org/10.1172/JCI42532.
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  - Mendel, J. B., K. D. Chavin, C. Bratton, and S. J. Knechtle. “HLA-C and liver transplant outcomes: interpreting the facts.” Am J Transplant, July 2009. https://doi.org/10.1111/j.1600-6143.2009.02718.x.
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  - Soltys, K. A., G. V. Mazariegos, R. H. Squires, R. K. Sindhi, R. Anand, and R. SPLIT Research Group. “Late graft loss or death in pediatric liver transplantation: an analysis of the SPLIT database.” Am J Transplant, September 2007. https://doi.org/10.1111/j.1600-6143.2007.01893.x.
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  - Diamond, Ivan R., Annie Fecteau, J Michael Millis, Julian E. Losanoff, Vicky Ng, Ravinder Anand, Changhong Song, and Changhong SPLIT Research Group. “Impact of graft type on outcome in pediatric liver transplantation: a report From Studies of Pediatric Liver Transplantation (SPLIT).” Ann Surg, August 2007. https://doi.org/10.1097/SLA.0b013e3180caa415.
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  - Bonatti, Hugo, Justin H. Nguyen, Stuart J. Knechtle, and Timothy L. Pruett. “Liver transplantation 2007: where do we go from here?” Curr Opin Organ Transplant, June 2007. https://doi.org/10.1097/MOT.0b013e32819380ee.
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  - Xu, Q., J. Lee, E. Jankowska-Gan, J. Schultz, D. A. Roennburg, L. D. Haynes, S. Kusaka, et al. “Human CD4+CD25low adaptive T regulatory cells suppress delayed-type hypersensitivity during transplant tolerance.” The Journal of Immunology. The American Association of Immunologists, June 1, 2007. https://doi.org/10.4049/jimmunol.178.11.7488.
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  - Knechtle, S., G. Remuzzi, and R. M. Strieter. “Editorial introductions.” Current Opinion in Organ Transplantation, December 1, 2004.
  - Knechtle, S. J. “Editorial.” Transplantation Reviews, July 1, 2004. https://doi.org/10.1016/S0955-470X(04)00091-6.
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  - Knechtle, S. J. “Editorial.” Transplantation Reviews, April 1, 2004. https://doi.org/10.1016/j.trre.2004.04.005.
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  - Knechtle, Stuart J. “Challenging choices: liver transplantation for hepatocellular carcinoma.” Ann Surg, February 2004. https://doi.org/10.1097/01.sla.0000109169.72607.50.
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  - Knechtle, S. J. “Conclusion.” Transplantation Reviews, January 1, 2003. https://doi.org/10.1016/j.trre.2003.07.001.
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  - Knechtle, S. J. “Alemtuzumab and tolerance: The University of Wisconsin experience.” Transplantation Reviews, January 1, 2003. https://doi.org/10.1016/j.trre.2003.07.002.
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  - Paul, L. C., and S. J. Knechtle. “A new beginning.” Transplantation Reviews, January 1, 2003. https://doi.org/10.1053/trre.2003.7.
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  - Knechtle, S. J., G. Opelz, R. Margreiter, and B. Döhler. “Why is it better to transplant the kidney plus another organ?” Transplantation, November 1, 2002. https://doi.org/10.1097/00007890-200211270-00003.
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  - Knechtle, S. J., and L. F. Rikkers. “Portacaval shunts for ascites: Another perspective (vol 184, pg 650, 1997).” Journal of the American College of Surgeons. ELSEVIER SCIENCE INC, September 1, 1997.
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  - Knechtle, S. J., and L. F. Rikkers. “Portacaval shunts for ascites: another perspective.” J Am Coll Surg, June 1997.
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  - Knechtle, S. J., M. Kalayoglu, A. M. D’Alessandro, and L. F. Rikkers. “Proceed with caution: liver transplantation for metastatic neuroendocrine tumors.” Ann Surg, April 1997. https://doi.org/10.1097/00000658-199704000-00001.
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  - Knechtle, S. J., and L. F. Rikkers. “Erratum: Metabolic results of side-to-side portacaval shunt for intractable cirrhotic ascites (Journal of the American College of Surgeons (1997) 184 (557-570)).” Journal of the American College of Surgeons, January 1, 1997.
  - Knechtle, S. J., G. L. Jin, J. M. Henderson, N. C. Estes, J. G. Turcotte, and J. P. Delaney. “Transabdominal esophagogastric devascularization as treatment for variceal hemorrhage - Discussion.” Surgery. MOSBY-YEAR BOOK INC, October 1, 1996.
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  - Knechtle, S. J., R. Marshall, S. Sterioff, D. Sutherland, S. Steinberg, and M. Malangoni. “Adverse effect of donor vasopressor support on immediate and one-year kidney allograft function - Discussion.” Surgery. MOSBY-YEAR BOOK INC, October 1, 1996.
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  - Yang, H., S. J. Knechtle, and R. Pollak. “Impact of improving immunosuppressive treatment on outcome in cadaveric kidney transplantation - Discussion.” Surgery. MOSBY-YEAR BOOK INC, October 1, 1996.
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  - Knechtle, S. J., E. C. Halperin, and R. R. Bollinger. “The effect of TLI and cyclosporine on xenograft survival.” Transplantation, December 1990. https://doi.org/10.1097/00007890-199012000-00046.
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- Conference Papers
  - Jelly, E. T., W. Kendall, R. Schmitz, S. J. Knechtle, D. L. Sudan, A. Joseph, J. Roper, J. Kwun, and A. Wax. “Novel implementations of optical coherence tomography for clinical applications in the lower gastrointestinal tract.” In Optics Infobase Conference Papers, Vol. Part F180-OCT-2020, 2020.
  - Knechtle, Stuart J., Faouzi Saliba, Bjorn Nashan, El-Djouher Martzloff, Pascal Espie, Antonio Speziale, and Sandy Feng. “EFFICACY, SAFETY, PHARMACOKINETICS AND PHARMACODYNAMICS OF THE ANTI-CD40 MONOCLONAL ANTIBODY ISCALIMAB (CFZ533) IN DE NOVO LIVER TRANSPLANT RECIPIENTS: RATIONALE AND DESIGN OF THE CONTRAIL I STUDY.” In Transplant International, 32:341–341. WILEY, 2019.
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  - Kwun, Jean, Janghoon Yoon, Adella Clark, Dong-Feng Chen, Stuart J. Knechtle, and Annette M. Jackson. “P153 Utilizing single HLA antigen beads to sensitized nonhuman primate model.” In Human Immunology, 80:174–174. Elsevier BV, 2019. https://doi.org/10.1016/j.humimm.2019.07.206.
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  - Freischlag, Kyle, Brian Ezekian, Paul M. Schroder, Michael S. Mulvihill, Morgan L. Cox, Matthew G. Hartwig, and Stuart Knechtle. “A Propensity-matched Survival Analysis: Do Simultaneous Liver-lung Transplant Recipients Need a Liver?” In Transplantation, 103:1675–82, 2019. https://doi.org/10.1097/TP.0000000000002529.
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  - Schmitz, R., M. S. Mulvihill, P. M. Schroder, Z. Fitch, F. Leopardi, D. Magnani, J. Kwun, S. J. Knechtle, and A. D. Kirk. “Depletional Induction Therapy in Non-Human Primates - Preclinical Modeling of Polyclonal Depletion with Rhesus-Specific ATG.” In American Journal of Transplantation, 19:597–597. WILEY, 2019.
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  - Schroder, P. M., R. Schmitz, Z. Fitch, B. Ezekian, J. Yoon, A. Choi, A. Barbas, et al. “Dual Targeting Desensitization with Carfilzomib Plus Lulizumab Significantly Prolongs Kidney Transplant Survival in Allosensitized Nonhuman Primates.” In American Journal of Transplantation, 19:429–429. WILEY, 2019.
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  - Schroder, P., J. S. Yi, K. J. Weinhold, C. Chan, M. Joshi, C. Walters, J. Kwun, and S. J. Knechtle. “Pre-Transplant Multidimensional Flow Cytometric Analysis of Kidney Transplant Recipients Reveals Novel Immune Signature of Allograft Rejection.” In American Journal of Transplantation, 19:765–66. WILEY, 2019.
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  - Schroder, P., J. Yoon, R. Schmitz, Z. Fitch, J. Kwun, and S. J. Knechtle. “Novel In Vitro Germinal Center Culture System Demonstrates More Aggressive B Cell to Plasma Blast Differentiation in Allosensitized Nonhuman Primates.” In American Journal of Transplantation, 19:1090–1090. WILEY, 2019.
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  - Burghuber, C. K., J. Kwun, E. J. Kim, F. V. Leopardi, A. C. Gibby, N. N. Iwakoshi, and S. J. Knechtle. “NEW DESENSITIZATION STRATEGY IN A KIDNEY TRANSPLANTATION MODEL WITH RHESUS MONKEYS.” In Transplant International, 28:12–12. WILEY-BLACKWELL, 2015.
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  - Shaffer, Katherine, Sungjin Kim, Anthony M. Gamboa, Jennifer A. Luke, Sunil Dacha, Andrew B. Adams, Stuart J. Knechtle, et al. “Incidence and Predictors of Lymph Nodal Metastases in Patients With Cholangiocarcinoma in the United States.” In Gastroenterology, 146:S994–S994. W B SAUNDERS CO-ELSEVIER INC, 2014.
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  - Haas, M., B. Sis, L. C. Racusen, K. Solez, D. Glotz, R. B. Colvin, M. C. R. Castro, et al. “Banff 2013 meeting report: inclusion of c4d-negative antibody-mediated rejection and antibody-associated arterial lesions.” In Am J Transplant, 14:272–83, 2014. https://doi.org/10.1111/ajt.12590.
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  - Ruhil, Ravi, Daniel Huang, Ozlem P. Bulut, Stuart J. Knechtle, Leslie S. Kean, and Neal N. Iwakoshi. “Humoral Immunity Induced By Viral Infection Provides a Major Barrier To Hematopoietic Cell Transplantation.” In Blood, 122:894–894. American Society of Hematology, 2013. https://doi.org/10.1182/blood.v122.21.894.894.
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  - Squires, Malcolm H., Steven Hanish, Sarah B. Fisher, Cristen Garrett, David Kooby, Juan M. Sarmiento, Kenneth Cardona, et al. “Transplant Versus Resection for the Management of Hepatocellular Carcinoma in the Post-2006 MELD Exception Era At a Single Institution in the Southeast UNOS Region.” In Gastroenterology, 144:S1058–S1058. W B SAUNDERS CO-ELSEVIER INC, 2013.
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  - Kawata, Kazuhito, Masanobu Tsuda, Guo-Xiang Yang, Weici Zhang, Hajime Tanaka, Koichi Tsuneyama, Patrick Leung, et al. “Identification of potential cytokine pathways for therapeutic intervention in murine primary biliary cirrhosis.” In Plos One, 8:e74225, 2013. https://doi.org/10.1371/journal.pone.0074225.
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  - Best, Victoria, Stuart J. Knechtle, Allan D. Kirk, and Arash Grakoui. “Potential role for intrahepatic CD34+cells in immunity to hepatitis C virus.” In Hepatology, 56:1109A-1110A. WILEY-BLACKWELL, 2012.
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  - Bulut, O. P., R. Ruhil, B. Oh, S. J. Knechtle, S. Talebagha, and N. N. Iwakoshi. “Phenotypic and Functional Analysis of Long-Lived Alloreactive Plasma Cells.” In American Journal of Transplantation, 12:51–51. WILEY-BLACKWELL, 2012.
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  - Kwun, J., B. Oh, A. Gibby, N. Iwakoshi, and S. J. Knechtle. “The Role of CD4(+)CD25(+) T reg Cells on Alloantibody Production in a Model of Chronic Rejection after T Cell Depletion.” In American Journal of Transplantation, 12:447–447. WILEY-BLACKWELL, 2012.
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  - Kwun, J., B. Oh, A. Gibby, R. Ruhil, V. Lu, O. P. Bulut, M. Song, et al. “Patterns of De Novo Allo B Cells and Antibody Formation in Chronic Cardiac Allograft Rejection after Alemtuzumab Treatment.” In American Journal of Transplantation, 12:278–278. WILEY-BLACKWELL, 2012.
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  - Magliocca, J. F., L. K. Kayler, S. I. Hanish, S. J. Knechtle, and J. D. Schold. “Significantly Greater Hazard Associated with the Use of Older Donor Livers in HCV plus Recipients.” In American Journal of Transplantation, 12:516–17. WILEY-BLACKWELL, 2012.
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  - Oh, B., J. Kwun, R. Ruhil, A. Gibby, E. Page, V. Lu, D. Kim, et al. “Rapamycin Enhances Donor-Specific Antibody and Chronic Rejection of Full MHC Mismatched Cardiac Allografts after Alemtuzumab Treatment.” In American Journal of Transplantation, 12:463–463. WILEY-BLACKWELL, 2012.
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  - Page, E. K., A. C. Gibby, J. Kwun, F. Leopardi, A. B. Adams, C. L. Courtney, J. B. Jenkins, E. Strobert, N. Iwakoshi, and S. J. Knechtle. “Belatacept Prevents De Novo Alloantibody Production in Rhesus Macaques.” In American Journal of Transplantation, 12:276–276. WILEY-BLACKWELL, 2012.
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  - Gupta, Nitika A., Jean Kwun, Allan D. Kirk, Frank A. Anania, Rene Romero, and Stuart J. Knechtle. “ROLE OF GLP-1R AGONISTS IN DECREASING HEPATIC STEATOSIS AND APOPTOSIS IN OB/OB MICE UNDERGOING ISCHEMIA REPERFUSION INJURY.” In Hepatology, 52:1041A-1042A. WILEY-BLACKWELL, 2010.
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  - Agarwal, A., H. M. Gebel, R. A. Bray, C. Watkins, K. E. Kokko, T. C. Pearson, and S. J. Knechtle. “Liver Transplantation Removes MHC Class I but Not Class II Antibody from Sensitized Recipients of Combined Liver/Kidney Transplants.” In American Journal of Transplantation, 10:100–100. WILEY-BLACKWELL PUBLISHING, INC, 2010.
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  - Bartosh, Sharon M., Cheryl P. Sanchez, Beth A. Gerndt-Spaith, Hans W. Sollinger, and Stuart J. Knechtle. “Steroid Free Immunosuppression in Pediatric Kidney Transplants (TX) Following Induction with Campath.” In American Journal of Transplantation, 10:512–13. WILEY-BLACKWELL PUBLISHING, INC, 2010.
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  - Bloom, Debra D., Rushin Brahmbhatt, and Stuart J. Knechtle. “Flow cytometric characterization of regulatory T lymphocyte populations in renal transplant patients treated with campath and tacrolimus.” In American Journal of Transplantation, 7:208–208. BLACKWELL PUBLISHING, 2007.
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  - Jankowska-Gan, Ewa, Drew Roennenburg, Stuart J. Knechtle, William J. Burlingham, and Jose R. Torrealba. “Histopathologic evidence for linked suppression detected by the trans-vivo DTH: Footpad differs from ear.” In American Journal of Transplantation, 7:579–579. BLACKWELL PUBLISHING, 2007.
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  - Torrealba, Jose R., Julio Pascual, Felipe Lopez, John Pirsch, Stuart J. Knechtle, and Milaeros Samaniego. “Focal vs. diffuse pattern of C4d immunolabeling of renal allografts: Association and evolution to transplant glomerulopathy.” In American Journal of Transplantation, 7:261–261. BLACKWELL PUBLISHING, 2007.
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  - Barth, R. N., C. A. Janus, C. A. Lillesand, N. A. Radke, J. D. Pirsch, B. N. Becker, L. A. Fernandez, et al. “Three-year success of Campath-1H induction for renal transplantation.” In American Journal of Transplantation, 5:569–569. BLACKWELL PUBLISHING, 2005.
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  - Pirsch, J. D., A. M. D’Alessandro, S. J. Knechtle, H. W. Sollinger, F. O. Belzer, and M. Kalayoglu. “Effect of cyclosporine on renal function in survivors of liver transplantation after 1 year.” In Transplantation Proceedings, 25:13–14, 1993.
  - Sasaki, T., J. D. Pirsch, R. J. Ploeg, M. D. Stegall, A. M. D’Alessandro, S. J. Knechtle, F. O. Belzer, and H. W. Sollinger. “Effects of DR mismatch on long-term graft survival in simultaneous kidney- pancreas transplantation.” In Transplantation Proceedings, 25:237–38, 1993.
  - Wang, J., E. Geissler, and S. J. Knechtle. “In Vivo transfer of gene encoding soluble MHC class I prolongs heart transplant survival.” In Human Immunology, 37:131, 1993. https://doi.org/10.1016/0198-8859(93)90172-W.
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  - BELZER, F. O., J. H. SOUTHARD, R. M. HOFFMANN, R. J. PLOEG, S. J. KNECHTLE, A. M. DALESSANDRO, J. D. PIRSCH, M. KALAYOGLU, and H. W. SOLLINGER. “EVALUATION OF PRESERVATION OF THE VARIOUS ORGANS FOR TRANSPLANTATION.” In Transplantation and Clinical Immunology, Vol 24, edited by J. L. Touraine, J. Traeger, H. Betuel, J. M. Dubernard, J. P. Revillard, and C. Dupuy, 18:199–208. ELSEVIER SCIENCE PUBL B V, 1992.
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  - D’Alessandro, A. M., M. Kalayoglu, H. W. Sollinger, R. M. Hoffmann, A. Reed, S. J. Knechtle, J. D. Pirsch, G. R. Hafez, D. Lorentzen, and F. O. Belzer. “The predictive value of donor liver biopsies on the development of primary nonfunction after orthotopic liver transplantation.” In Transplantation Proceedings, 23:1536–37, 1991.
  - Knechtle, S. J., J. D. Pirsch, M. Groshek, A. Reed, A. M. D’Alessandro, M. Kalayoglu, F. O. Belzer, and H. W. Sollinger. “OKT3 vs ALG induction therapy in combined pancreas-kidney transplantation.” In Transplantation Proceedings, 23:1581–82, 1991.
  - Pirsch, J. D., M. J. Armbrust, S. J. Knechtle, A. Reed, A. M. D’Alessandro, H. W. Sollinger, and F. O. Belzer. “Effect of steroid withdrawal on hypertension and cholesterol levels in living related recipients.” In Transplantation Proceedings, 23:1363–64, 1991.
  - Pirsch, J. D., M. Kalayoglu, A. M. D’Alessandro, M. J. Armbrust, A. Reed, S. J. Knechtle, H. W. Sollinger, and F. O. Belzer. “Orthotopic liver transplantation in patients over 60 years of age.” In Transplantation Proceedings, 23:1456–57, 1991.
  - Reed, A., J. D. Pirsch, M. J. Armbrust, W. J. Burlingham, S. J. Knechtle, A. M. D’Alessandro, H. W. Sollinger, M. Kalayoglu, and F. O. Belzer. “A comparison of donor-specific and random transfusions in living-related renal transplantation and their effect on steroid withdrawal.” In Transplantation Proceedings, 23:1321–22, 1991.
  - KALAYOGLU, M., A. M. DALESSANDRO, H. W. SOLLINGER, R. M. HOFFMANN, S. J. KNECHTLE, A. REED, J. D. PIRSCH, and F. O. BELZER. “ORTHOTOPIC LIVER-TRANSPLANTATION WITH REDUCED-SIZE LIVERS.” In Hepatology, 12:838–838. W B SAUNDERS CO, 1990.
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  - Bollinger, R. R., S. J. Knechtle, R. C. Harland, Y. Yamaguchi, and E. C. Halperin. “New approaches to immunosuppression for xenotransplantation.” In Xenograft 25: Proceedings of the International Congress, Xenograft 25. Ics880, 45–54, 1989.
Teaching & Mentoring
Advising & Mentoring
- Over the past 24 years, I have helped train over 6 graduate students, 18 post-doctoral fellows, 15 surgical research fellows, and 10 medical students in my research lab, and helped train over 50 transplant fellows in surgical transplantation.
Scholarly, Clinical, & Service Activities
Service to the Profession
- Council Member. American Society of Transplantation. 2004 - 2007 2004 - 2007

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