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Stuart Johnston Knechtle

William R. Kenan, Jr. Distinguished Professor of Surgery
Surgery, Abdominal Transplant Surgery

Selected Grants


Stimulating Access to Research in Residency (StARR) - NIAID

Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 2018 - 2029

Advanced Immunobiology Traning Program for Surgeons

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2019 - 2029

Targeting the B Cell Response to Treat Antibody-Mediated Rejection

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2021 - 2028

The Risks and Opportunities of Homeostatic Repopulation

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2022 - 2028

Overcoming humoral rejection after xenotransplantation in sensitized nonhuman primate recipients

ResearchCollaborator · Awarded by National Institute of Allergy and Infectious Diseases · 2023 - 2028

Development of a Publicly Available MHC Matchmaker Algorithm

ResearchMentor · Awarded by American Society of Histocompatibility and Immunogenetics · 2024 - 2025

Overcoming humoral rejection following xenotransplantation via targeting complement C3

ResearchCo Investigator · Awarded by Alexion Pharmaceuticals, Inc. · 2023 - 2025

VEL-101 NHP Study

ResearchPrincipal Investigator · Awarded by Veloxis Pharmaceuticals · 2023 - 2025

EVALUATION OF PATIENT OUTCOMES FROM THE KIDNEY ALLOGRAFT OUTCOMES ALLOSURE REGISTRY (KOAR) AGREEMENT

ResearchPrincipal Investigator · Awarded by CareDx, Inc. · 2018 - 2025

Mathematical modeling for optimal control of BK virus infection in kidney transplant recipients

ResearchCo Investigator · Awarded by National Institute of Allergy and Infectious Diseases · 2023 - 2025

Miromatrix SRA

ResearchPrincipal Investigator · Awarded by Miromatrix Medical Inc. · 2024 - 2025

Novel development ofan acoustofluidic device for targeted antibody removal in pediatric organ transplan rejection

ResearchCollaborator · Awarded by National Institutes of Health · 2021 - 2025

ITN089ST (ADAPT) - Measuring Allospecific Impact Of Belatacept/Carfilzomib Desensitization

Clinical TrialPrincipal Investigator · Awarded by Benaroya Research Institute at Virginia Mason · 2021 - 2025

ITN336 Immune Tolerance Network

ResearchPrincipal Investigator · Awarded by Benaroya Research Institute at Virginia Mason · 2019 - 2025

Transplant Infectious Diseases Interdisciplinary Research Training Grant (TIDIRTG)

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2018 - 2024

Duke CTSA (TL1) Year 5

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2018 - 2024

The Effect of a Desensitization Protocol in Highly Sensitized Renal Transplant Recipients on T Follicular Helper Cells

FellowshipPrincipal Investigator · Awarded by National Institutes of Health · 2023 - 2024

Investigation of complement blockade in murine heart transplant model

FellowshipPrincipal Investigator · Awarded by American Society of Transplant Surgeons · 2023 - 2024

Promoting humoral tolerance via targeting complement C3

ResearchCo Investigator · Awarded by The Board of Regents of the University of Wisconsin System · 2022 - 2024

AlloVir P105-401 Registry

Clinical TrialPrincipal Investigator · Awarded by Allovir, Inc. · 2022 - 2024

IMAGINE

Clinical TrialPrincipal Investigator · Awarded by CSL Behring LLC · 2020 - 2024

Allo Vir ALVR105

Clinical TrialPrincipal Investigator · Awarded by Allovir, Inc. · 2021 - 2023

Antibody and B cell kinetics following IdeS (Imlipidase) administration in a sensitized non-human primate model

FellowshipPrincipal Investigator · Awarded by American Society of Transplant Surgeons · 2022 - 2023

Targeting complement C3 to prevent acute antibody-mediated rejection for a deceased-donor kidney transplant in sensitized recipients

ResearchPrincipal Investigator · Awarded by Alexion Pharmaceuticals, Inc. · 2021 - 2023

Acoustic Device to Prevent Antibody Mediated Organ Transplant Failure

ResearchCollaborator · Awarded by Hartwell Foundation · 2019 - 2023

LET vs VGCV for Prevention of CMV disease in Kidney Transplant Recipients

Clinical TrialPrincipal Investigator · Awarded by Merck Sharp & Dohme · 2017 - 2023

Alexion Sponsored Research Agreement

ResearchPrincipal Investigator · Awarded by Alexion Pharmaceuticals, Inc. · 2020 - 2022

The Risks and Opporunities of Homeostatic Repopulation

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2017 - 2022

Measuring the Impact of Allosensitization on Xenotransplantation

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2020 - 2022

IM101-823 - Abatacept for treatment of recurrent or de novo autoimmune hepatitis

Clinical TrialPrincipal Investigator · Awarded by The Bristol-Myers/Sanofi Pharmaceuticals, Inc. Partnership · 2019 - 2021

Acoustic based plasmapheresis to prevent antibody-mediated organ transplant

ResearchCo Investigator · Awarded by The Board of Regents of the University of Wisconsin System · 2019 - 2021

Lung Transplant Plasmapheresis (PLEX)/Belatacept/Carfilzomib Protocol for Treatment of Antibody Mediated Rejection (AMR) and Desensitization

Clinical TrialPrincipal Investigator · Awarded by Bristol-Myers Squibb Company · 2019 - 2020

ASTS Presidential Student Mentor Grant

FellowshipPrincipal Investigator · Awarded by American Society of Transplant Surgeons · 2019 - 2019

Transplant Tolerance in Non-Human Primates

ResearchPrincipal Investigator · Awarded by Emory University · 2015 - 2017

Preventing allograft rejection but not tolerance by blockade of the lymphocyte store-operated calcium channel

ResearchPrincipal Investigator · Awarded by Department of Defense · 2016 - 2017

Visiting Research Fellowship

FellowshipPrincipal Investigator · Awarded by King's College London · 2015 - 2016

Prevention of Homograft Induced Cardiac Allograft Vasculopathy in Pediatric Heart Transplantation

ResearchCollaborator · Awarded by Enduring Hearts · 2015 - 2016

Preventing allograft rejection but not tolerance by blockade of the lymphocyte store-operated calcium channel

ResearchPrincipal Investigator · Awarded by Synta Pharmaceuticals Corp. · 2015 - 2016

Inducible Regulatory B Cells in Transplantation Tolerance

ResearchPrincipal Investigator · Awarded by University of Wisconsin · 2015 - 2016

External Relationships


  • Mallinckrodt Pharmaceuticals
  • Alexion Pharmaceuticals, Inc. a subsidiary of AstraZeneca
  • Allovir
  • Hanall BioPharma
  • Hansa BioPharma
  • Pfizer Inc.
  • Renovar
  • Summome
  • Visterra

This faculty member (or a member of their immediate family) has reported outside activities with the companies, institutions, or organizations listed above. This information is available to institutional leadership and, when appropriate, management plans are in place to address potential conflicts of interest.