LOCAL TRANSLATION. Comment on "Principles of ER cotranslational translocation revealed by proximity-specific ribosome profiling".
Publication
, Journal Article
Reid, DW; Nicchitta, CV
Published in: Science
June 12, 2015
Jan et al. (Research Articles, 7 November 2014, p. 716) propose that ribosomes translating secretome messenger RNAs (mRNAs) traffic from the cytosol to the endoplasmic reticulum (ER) upon emergence of the signal peptide and return to the cytosol after termination. An accounting of controls demonstrates that mRNAs initiate translation on ER-bound ribosomes and that ribosomes are retained on the ER through many cycles of translation.
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Published In
Science
DOI
EISSN
1095-9203
Publication Date
June 12, 2015
Volume
348
Issue
6240
Start / End Page
1217
Location
United States
Related Subject Headings
- Ribosomes
- Protein Biosynthesis
- Mitochondria
- Humans
- General Science & Technology
- Endoplasmic Reticulum
- Cells
Citation
APA
Chicago
ICMJE
MLA
NLM
Reid, D. W., & Nicchitta, C. V. (2015). LOCAL TRANSLATION. Comment on "Principles of ER cotranslational translocation revealed by proximity-specific ribosome profiling". Science, 348(6240), 1217. https://doi.org/10.1126/science.aaa7257
Reid, David W., and Christopher V. Nicchitta. “LOCAL TRANSLATION. Comment on "Principles of ER cotranslational translocation revealed by proximity-specific ribosome profiling".” Science 348, no. 6240 (June 12, 2015): 1217. https://doi.org/10.1126/science.aaa7257.
Reid DW, Nicchitta CV. LOCAL TRANSLATION. Comment on "Principles of ER cotranslational translocation revealed by proximity-specific ribosome profiling". Science. 2015 Jun 12;348(6240):1217.
Reid, David W., and Christopher V. Nicchitta. “LOCAL TRANSLATION. Comment on "Principles of ER cotranslational translocation revealed by proximity-specific ribosome profiling".” Science, vol. 348, no. 6240, June 2015, p. 1217. Pubmed, doi:10.1126/science.aaa7257.
Reid DW, Nicchitta CV. LOCAL TRANSLATION. Comment on "Principles of ER cotranslational translocation revealed by proximity-specific ribosome profiling". Science. 2015 Jun 12;348(6240):1217.
Published In
Science
DOI
EISSN
1095-9203
Publication Date
June 12, 2015
Volume
348
Issue
6240
Start / End Page
1217
Location
United States
Related Subject Headings
- Ribosomes
- Protein Biosynthesis
- Mitochondria
- Humans
- General Science & Technology
- Endoplasmic Reticulum
- Cells