Outer-membrane vesicles from Gram-negative bacteria: biogenesis and functions.
Publication
, Journal Article
Schwechheimer, C; Kuehn, MJ
Published in: Nat Rev Microbiol
October 2015
Outer-membrane vesicles (OMVs) are spherical buds of the outer membrane filled with periplasmic content and are commonly produced by Gram-negative bacteria. The production of OMVs allows bacteria to interact with their environment, and OMVs have been found to mediate diverse functions, including promoting pathogenesis, enabling bacterial survival during stress conditions and regulating microbial interactions within bacterial communities. Additionally, because of this functional versatility, researchers have begun to explore OMVs as a platform for bioengineering applications. In this Review, we discuss recent advances in the study of OMVs, focusing on new insights into the mechanisms of biogenesis and the functions of these vesicles.
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Published In
Nat Rev Microbiol
DOI
EISSN
1740-1534
Publication Date
October 2015
Volume
13
Issue
10
Start / End Page
605 / 619
Location
England
Related Subject Headings
- Organelle Biogenesis
- Microbiology
- Gram-Negative Bacteria
- Drug Resistance, Bacterial
- Cell Membrane Structures
- 3107 Microbiology
- 1108 Medical Microbiology
- 0605 Microbiology
Citation
APA
Chicago
ICMJE
MLA
NLM
Schwechheimer, C., & Kuehn, M. J. (2015). Outer-membrane vesicles from Gram-negative bacteria: biogenesis and functions. Nat Rev Microbiol, 13(10), 605–619. https://doi.org/10.1038/nrmicro3525
Schwechheimer, Carmen, and Meta J. Kuehn. “Outer-membrane vesicles from Gram-negative bacteria: biogenesis and functions.” Nat Rev Microbiol 13, no. 10 (October 2015): 605–19. https://doi.org/10.1038/nrmicro3525.
Schwechheimer C, Kuehn MJ. Outer-membrane vesicles from Gram-negative bacteria: biogenesis and functions. Nat Rev Microbiol. 2015 Oct;13(10):605–19.
Schwechheimer, Carmen, and Meta J. Kuehn. “Outer-membrane vesicles from Gram-negative bacteria: biogenesis and functions.” Nat Rev Microbiol, vol. 13, no. 10, Oct. 2015, pp. 605–19. Pubmed, doi:10.1038/nrmicro3525.
Schwechheimer C, Kuehn MJ. Outer-membrane vesicles from Gram-negative bacteria: biogenesis and functions. Nat Rev Microbiol. 2015 Oct;13(10):605–619.
Published In
Nat Rev Microbiol
DOI
EISSN
1740-1534
Publication Date
October 2015
Volume
13
Issue
10
Start / End Page
605 / 619
Location
England
Related Subject Headings
- Organelle Biogenesis
- Microbiology
- Gram-Negative Bacteria
- Drug Resistance, Bacterial
- Cell Membrane Structures
- 3107 Microbiology
- 1108 Medical Microbiology
- 0605 Microbiology