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Marked Hypofibrinogenemia and Gastrointestinal Bleeding After Copperhead (Agkistrodon contortrix) Envenomation.

Publication ,  Journal Article
Kopec, KT; Yen, M; Bitner, M; Evans, CS; Gerardo, CJ
Published in: Wilderness Environ Med
December 2015

Compared with other crotaline envenomations, copperhead envenomations have historically been reported as having less severe hematologic venom effects and rarely hemorrhage. We report a case of clinically significant gastrointestinal bleeding after a copperhead (Agkistrodon contortrix) envenomation. A 52-year-old woman with a history of systemic lupus erythematosus was bitten on her right medial ankle after which hypofibrinogenemia and hematochezia developed. The symptoms resolved after repeated administration of Crotalidae polyvalent immune Fab (ovine) antivenom. She was discharged without further complications 2 days later. Although copperhead envenomations are classically considered less severe than other crotaline envenomations, this case demonstrates the potential of the venom to produce clinically significant hematologic effects.

Duke Scholars

Published In

Wilderness Environ Med

DOI

EISSN

1545-1534

Publication Date

December 2015

Volume

26

Issue

4

Start / End Page

488 / 490

Location

United States

Related Subject Headings

  • Snake Bites
  • Middle Aged
  • Immunoglobulin Fab Fragments
  • Humans
  • General & Internal Medicine
  • Gastrointestinal Hemorrhage
  • Female
  • Crotalid Venoms
  • Antivenins
  • Animals
 

Citation

APA
Chicago
ICMJE
MLA
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Kopec, K. T., Yen, M., Bitner, M., Evans, C. S., & Gerardo, C. J. (2015). Marked Hypofibrinogenemia and Gastrointestinal Bleeding After Copperhead (Agkistrodon contortrix) Envenomation. Wilderness Environ Med, 26(4), 488–490. https://doi.org/10.1016/j.wem.2015.07.002
Kopec, Kathryn T., May Yen, Matthew Bitner, C Scott Evans, and Charles J. Gerardo. “Marked Hypofibrinogenemia and Gastrointestinal Bleeding After Copperhead (Agkistrodon contortrix) Envenomation.Wilderness Environ Med 26, no. 4 (December 2015): 488–90. https://doi.org/10.1016/j.wem.2015.07.002.
Kopec KT, Yen M, Bitner M, Evans CS, Gerardo CJ. Marked Hypofibrinogenemia and Gastrointestinal Bleeding After Copperhead (Agkistrodon contortrix) Envenomation. Wilderness Environ Med. 2015 Dec;26(4):488–90.
Kopec, Kathryn T., et al. “Marked Hypofibrinogenemia and Gastrointestinal Bleeding After Copperhead (Agkistrodon contortrix) Envenomation.Wilderness Environ Med, vol. 26, no. 4, Dec. 2015, pp. 488–90. Pubmed, doi:10.1016/j.wem.2015.07.002.
Kopec KT, Yen M, Bitner M, Evans CS, Gerardo CJ. Marked Hypofibrinogenemia and Gastrointestinal Bleeding After Copperhead (Agkistrodon contortrix) Envenomation. Wilderness Environ Med. 2015 Dec;26(4):488–490.
Journal cover image

Published In

Wilderness Environ Med

DOI

EISSN

1545-1534

Publication Date

December 2015

Volume

26

Issue

4

Start / End Page

488 / 490

Location

United States

Related Subject Headings

  • Snake Bites
  • Middle Aged
  • Immunoglobulin Fab Fragments
  • Humans
  • General & Internal Medicine
  • Gastrointestinal Hemorrhage
  • Female
  • Crotalid Venoms
  • Antivenins
  • Animals