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Major vascular resection as part of pancreaticoduodenectomy for cancer: radiologic, intraoperative, and pathologic analysis.

Publication ,  Journal Article
Bold, RJ; Charnsangavej, C; Cleary, KR; Jennings, M; Madray, A; Leach, SD; Abbruzzese, JL; Pisters, PW; Lee, JE; Evans, DB
Published in: J Gastrointest Surg
1999

Intraoperative assessment is inaccurate in defining the relationship of a pancreatic head neoplasm to adjacent vascular structures. We evaluated the ability of preoperative contrast-enhanced CT to predict the need for vascular resection during pancreaticoduodenectomy and examined the resected vessels for histologic evidence of tumor invasion. During a 7-year period, 63 patients underwent pancreaticoduodenectomy with en bloc resection of adjacent vascular structures for a presumed pancreatic head malignancy. Clinical, radiologic, operative, and pathologic data were reviewed and analyzed. Fifty-six patients underwent resection of the superior mesenteric-portal vein confluence, three patients required inferior vena cava resection, and the hepatic artery was resected and reconstructed in eight patients. The operative mortality rate was 1.6%, and the overall complication rate was 22%. CT predicted the need for resection of the superior mesenteric or portal veins in 84% of patients. Pathologic analysis revealed tumor invasion of the vein wall in 71% of resected specimens. Tumor invasion of vascular structures adjacent to the pancreas can be predicted with preoperative CT and should alert the surgeon that vascular resection may be required. Histologic evidence of tumor cell infiltration of vessel walls was present in the majority of the resected specimens.

Duke Scholars

Published In

J Gastrointest Surg

DOI

ISSN

1091-255X

Publication Date

1999

Volume

3

Issue

3

Start / End Page

233 / 243

Location

United States

Related Subject Headings

  • Vena Cava, Inferior
  • Vascular Surgical Procedures
  • Tomography, X-Ray Computed
  • Survival Rate
  • Surgery
  • Radiographic Image Enhancement
  • Portal Vein
  • Pancreaticoduodenectomy
  • Pancreatic Neoplasms
  • Pancreas
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Bold, R. J., Charnsangavej, C., Cleary, K. R., Jennings, M., Madray, A., Leach, S. D., … Evans, D. B. (1999). Major vascular resection as part of pancreaticoduodenectomy for cancer: radiologic, intraoperative, and pathologic analysis. J Gastrointest Surg, 3(3), 233–243. https://doi.org/10.1016/s1091-255x(99)80065-1
Bold, R. J., C. Charnsangavej, K. R. Cleary, M. Jennings, A. Madray, S. D. Leach, J. L. Abbruzzese, P. W. Pisters, J. E. Lee, and D. B. Evans. “Major vascular resection as part of pancreaticoduodenectomy for cancer: radiologic, intraoperative, and pathologic analysis.J Gastrointest Surg 3, no. 3 (1999): 233–43. https://doi.org/10.1016/s1091-255x(99)80065-1.
Bold RJ, Charnsangavej C, Cleary KR, Jennings M, Madray A, Leach SD, et al. Major vascular resection as part of pancreaticoduodenectomy for cancer: radiologic, intraoperative, and pathologic analysis. J Gastrointest Surg. 1999;3(3):233–43.
Bold, R. J., et al. “Major vascular resection as part of pancreaticoduodenectomy for cancer: radiologic, intraoperative, and pathologic analysis.J Gastrointest Surg, vol. 3, no. 3, 1999, pp. 233–43. Pubmed, doi:10.1016/s1091-255x(99)80065-1.
Bold RJ, Charnsangavej C, Cleary KR, Jennings M, Madray A, Leach SD, Abbruzzese JL, Pisters PW, Lee JE, Evans DB. Major vascular resection as part of pancreaticoduodenectomy for cancer: radiologic, intraoperative, and pathologic analysis. J Gastrointest Surg. 1999;3(3):233–243.

Published In

J Gastrointest Surg

DOI

ISSN

1091-255X

Publication Date

1999

Volume

3

Issue

3

Start / End Page

233 / 243

Location

United States

Related Subject Headings

  • Vena Cava, Inferior
  • Vascular Surgical Procedures
  • Tomography, X-Ray Computed
  • Survival Rate
  • Surgery
  • Radiographic Image Enhancement
  • Portal Vein
  • Pancreaticoduodenectomy
  • Pancreatic Neoplasms
  • Pancreas