Chemoprevention of pancreatic cancer: ready for the clinic?
Publication
, Journal Article
Logsdon, CD; Abbruzzese, JL
Published in: Cancer Prev Res (Phila)
November 2010
Advances in our molecular, clinical, and epidemiologic understanding of the risk and development of pancreatic cancer offer hope for preventing this disease, which is largely intractable once developed. This perspective on provocative, genetically engineered mouse model work reported by Mohammed et al. (beginning on page 1417 in this issue of the journal) examines the prospects for pancreatic cancer chemoprevention with epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKI). Despite having limited value in advanced pancreatic cancer, EGFR TKIs show promise in the setting of early pancreatic carcinogenesis.
Duke Scholars
Published In
Cancer Prev Res (Phila)
DOI
EISSN
1940-6215
Publication Date
November 2010
Volume
3
Issue
11
Start / End Page
1375 / 1378
Location
United States
Related Subject Headings
- Quinazolines
- Protein Kinase Inhibitors
- Pancreatic Neoplasms
- Oncology & Carcinogenesis
- Mice
- Humans
- Gefitinib
- ErbB Receptors
- Chemoprevention
- Antineoplastic Agents
Citation
APA
Chicago
ICMJE
MLA
NLM
Logsdon, C. D., & Abbruzzese, J. L. (2010). Chemoprevention of pancreatic cancer: ready for the clinic? Cancer Prev Res (Phila), 3(11), 1375–1378. https://doi.org/10.1158/1940-6207.CAPR-10-0216
Logsdon, Craig D., and James L. Abbruzzese. “Chemoprevention of pancreatic cancer: ready for the clinic?” Cancer Prev Res (Phila) 3, no. 11 (November 2010): 1375–78. https://doi.org/10.1158/1940-6207.CAPR-10-0216.
Logsdon CD, Abbruzzese JL. Chemoprevention of pancreatic cancer: ready for the clinic? Cancer Prev Res (Phila). 2010 Nov;3(11):1375–8.
Logsdon, Craig D., and James L. Abbruzzese. “Chemoprevention of pancreatic cancer: ready for the clinic?” Cancer Prev Res (Phila), vol. 3, no. 11, Nov. 2010, pp. 1375–78. Pubmed, doi:10.1158/1940-6207.CAPR-10-0216.
Logsdon CD, Abbruzzese JL. Chemoprevention of pancreatic cancer: ready for the clinic? Cancer Prev Res (Phila). 2010 Nov;3(11):1375–1378.
Published In
Cancer Prev Res (Phila)
DOI
EISSN
1940-6215
Publication Date
November 2010
Volume
3
Issue
11
Start / End Page
1375 / 1378
Location
United States
Related Subject Headings
- Quinazolines
- Protein Kinase Inhibitors
- Pancreatic Neoplasms
- Oncology & Carcinogenesis
- Mice
- Humans
- Gefitinib
- ErbB Receptors
- Chemoprevention
- Antineoplastic Agents