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Past and present treatment of pancreatic adenocarcinoma: chemotherapy as a standard treatment modality.

Publication ,  Conference
Abbruzzese, JL
Published in: Semin Oncol
December 2002

Pancreatic cancer continues to be a challenging therapeutic problem, with approximately 28,000 deaths annually in the United States. Most studies of single-agent or combination chemotherapy in the treatment of patients with advanced adenocarcinoma of the pancreas have documented low response rates and little reproducible impact on patient survival or quality of life. However, the recent success of gemcitabine in patients with locally advanced and metastatic pancreatic cancer suggests that systemic therapy can have a beneficial effect on the natural history of this disease. Also, the rapidly evolving understanding of the molecular biology of pancreatic cancer may contribute to the development and use of targeted therapies with novel agents for even more effective treatments in the near future.

Duke Scholars

Published In

Semin Oncol

DOI

ISSN

0093-7754

Publication Date

December 2002

Volume

29

Issue

6 Suppl 20

Start / End Page

2 / 8

Location

United States

Related Subject Headings

  • Treatment Failure
  • Transcription Factors
  • Taxoids
  • Signal Transduction
  • Pancreatic Neoplasms
  • Paclitaxel
  • Oncology & Carcinogenesis
  • Humans
  • Gene Expression Regulation, Neoplastic
  • Gemcitabine
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Abbruzzese, J. L. (2002). Past and present treatment of pancreatic adenocarcinoma: chemotherapy as a standard treatment modality. In Semin Oncol (Vol. 29, pp. 2–8). United States. https://doi.org/10.1053/sonc.2002.37382
Abbruzzese, James L. “Past and present treatment of pancreatic adenocarcinoma: chemotherapy as a standard treatment modality.” In Semin Oncol, 29:2–8, 2002. https://doi.org/10.1053/sonc.2002.37382.
Abbruzzese, James L. “Past and present treatment of pancreatic adenocarcinoma: chemotherapy as a standard treatment modality.Semin Oncol, vol. 29, no. 6 Suppl 20, 2002, pp. 2–8. Pubmed, doi:10.1053/sonc.2002.37382.
Journal cover image

Published In

Semin Oncol

DOI

ISSN

0093-7754

Publication Date

December 2002

Volume

29

Issue

6 Suppl 20

Start / End Page

2 / 8

Location

United States

Related Subject Headings

  • Treatment Failure
  • Transcription Factors
  • Taxoids
  • Signal Transduction
  • Pancreatic Neoplasms
  • Paclitaxel
  • Oncology & Carcinogenesis
  • Humans
  • Gene Expression Regulation, Neoplastic
  • Gemcitabine