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Safety and efficacy of high-dose intravenous acyclovir in the management of neonatal herpes simplex virus infections.

Publication ,  Journal Article
Kimberlin, DW; Lin, CY; Jacobs, RF; Powell, DA; Corey, L; Gruber, WC; Rathore, M; Bradley, JS; Diaz, PS; Kumar, M; Arvin, AM; Gutierrez, K ...
Published in: Pediatrics
August 2001

OBJECTIVE: The objective of this investigation was to establish the safety of high-dose (HD) acyclovir for the treatment of neonatal herpes simplex virus (HSV) disease. In addition, an estimate of therapeutic efficacy was sought, both with respect to mortality and to morbidity. Virologic efficacy of HD acyclovir was also assessed. PARTICIPANTS: Infants who were

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Published In

Pediatrics

DOI

EISSN

1098-4275

Publication Date

August 2001

Volume

108

Issue

2

Start / End Page

230 / 238

Location

United States

Related Subject Headings

  • Pediatrics
  • Injections, Intravenous
  • Infusions, Intravenous
  • Infant, Newborn
  • Humans
  • Herpes Simplex
  • Drug Administration Schedule
  • Acyclovir
  • 52 Psychology
  • 42 Health sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Kimberlin, D. W., Lin, C. Y., Jacobs, R. F., Powell, D. A., Corey, L., Gruber, W. C., … National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group, . (2001). Safety and efficacy of high-dose intravenous acyclovir in the management of neonatal herpes simplex virus infections. Pediatrics, 108(2), 230–238. https://doi.org/10.1542/peds.108.2.230
Kimberlin, D. W., C. Y. Lin, R. F. Jacobs, D. A. Powell, L. Corey, W. C. Gruber, M. Rathore, et al. “Safety and efficacy of high-dose intravenous acyclovir in the management of neonatal herpes simplex virus infections.Pediatrics 108, no. 2 (August 2001): 230–38. https://doi.org/10.1542/peds.108.2.230.
Kimberlin DW, Lin CY, Jacobs RF, Powell DA, Corey L, Gruber WC, et al. Safety and efficacy of high-dose intravenous acyclovir in the management of neonatal herpes simplex virus infections. Pediatrics. 2001 Aug;108(2):230–8.
Kimberlin, D. W., et al. “Safety and efficacy of high-dose intravenous acyclovir in the management of neonatal herpes simplex virus infections.Pediatrics, vol. 108, no. 2, Aug. 2001, pp. 230–38. Pubmed, doi:10.1542/peds.108.2.230.
Kimberlin DW, Lin CY, Jacobs RF, Powell DA, Corey L, Gruber WC, Rathore M, Bradley JS, Diaz PS, Kumar M, Arvin AM, Gutierrez K, Shelton M, Weiner LB, Sleasman JW, de Sierra TM, Weller S, Soong SJ, Kiell J, Lakeman FD, Whitley RJ, National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group. Safety and efficacy of high-dose intravenous acyclovir in the management of neonatal herpes simplex virus infections. Pediatrics. 2001 Aug;108(2):230–238.

Published In

Pediatrics

DOI

EISSN

1098-4275

Publication Date

August 2001

Volume

108

Issue

2

Start / End Page

230 / 238

Location

United States

Related Subject Headings

  • Pediatrics
  • Injections, Intravenous
  • Infusions, Intravenous
  • Infant, Newborn
  • Humans
  • Herpes Simplex
  • Drug Administration Schedule
  • Acyclovir
  • 52 Psychology
  • 42 Health sciences