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Application of photocrosslinkable hyaluronan as a corneal perforation sealant

Publication ,  Conference
Grinstaff, MW; Miki, D; Pfister-Serres, A; Dastgheib, KA; Smeds, KA; Inoue, M; Hatchell, DL
Published in: Annual International Conference of the IEEE Engineering in Medicine and Biology Proceedings
December 1, 1999

A novel photocrosslinkable methacrylated hyaluronic acid has been synthesized for use as a corneal perforation sealant. The adhesion strength of this hydrogel to an epithelial surface was quantitated in vitro. In vivo application of this biopolymer sealed 95% of experimental corneal perforations allowing for complete stromal healing and the re-establishment of the cornea.

Duke Scholars

Published In

Annual International Conference of the IEEE Engineering in Medicine and Biology Proceedings

ISSN

0589-1019

Publication Date

December 1, 1999

Volume

2

Start / End Page

717
 

Citation

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Grinstaff, M. W., Miki, D., Pfister-Serres, A., Dastgheib, K. A., Smeds, K. A., Inoue, M., & Hatchell, D. L. (1999). Application of photocrosslinkable hyaluronan as a corneal perforation sealant. In Annual International Conference of the IEEE Engineering in Medicine and Biology Proceedings (Vol. 2, p. 717).
Grinstaff, M. W., D. Miki, A. Pfister-Serres, K. A. Dastgheib, K. A. Smeds, M. Inoue, and D. L. Hatchell. “Application of photocrosslinkable hyaluronan as a corneal perforation sealant.” In Annual International Conference of the IEEE Engineering in Medicine and Biology Proceedings, 2:717, 1999.
Grinstaff MW, Miki D, Pfister-Serres A, Dastgheib KA, Smeds KA, Inoue M, et al. Application of photocrosslinkable hyaluronan as a corneal perforation sealant. In: Annual International Conference of the IEEE Engineering in Medicine and Biology Proceedings. 1999. p. 717.
Grinstaff, M. W., et al. “Application of photocrosslinkable hyaluronan as a corneal perforation sealant.” Annual International Conference of the IEEE Engineering in Medicine and Biology Proceedings, vol. 2, 1999, p. 717.
Grinstaff MW, Miki D, Pfister-Serres A, Dastgheib KA, Smeds KA, Inoue M, Hatchell DL. Application of photocrosslinkable hyaluronan as a corneal perforation sealant. Annual International Conference of the IEEE Engineering in Medicine and Biology Proceedings. 1999. p. 717.

Published In

Annual International Conference of the IEEE Engineering in Medicine and Biology Proceedings

ISSN

0589-1019

Publication Date

December 1, 1999

Volume

2

Start / End Page

717