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Three-dimensional photoacoustic endoscopic imaging of the rabbit esophagus.

Publication ,  Journal Article
Yang, JM; Favazza, C; Yao, J; Chen, R; Zhou, Q; Shung, KK; Wang, LV
Published in: PloS one
January 2015

We report photoacoustic and ultrasonic endoscopic images of two intact rabbit esophagi. To investigate the esophageal lumen structure and microvasculature, we performed in vivo and ex vivo imaging studies using a 3.8-mm diameter photoacoustic endoscope and correlated the images with histology. Several interesting anatomic structures were newly found in both the in vivo and ex vivo images, which demonstrates the potential clinical utility of this endoscopic imaging modality. In the ex vivo imaging experiment, we acquired high-resolution motion-artifact-free three-dimensional photoacoustic images of the vasculatures distributed in the walls of the esophagi and extending to the neighboring mediastinal regions. Blood vessels with apparent diameters as small as 190 μm were resolved. Moreover, by taking advantage of the dual-mode high-resolution photoacoustic and ultrasound endoscopy, we could better identify and characterize the anatomic structures of the esophageal lumen, such as the mucosal and submucosal layers in the esophageal wall, and an esophageal branch of the thoracic aorta. In this paper, we present the first photoacoustic images showing the vasculature of a vertebrate esophagus and discuss the potential clinical applications and future development of photoacoustic endoscopy.

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Published In

PloS one

DOI

EISSN

1932-6203

ISSN

1932-6203

Publication Date

January 2015

Volume

10

Issue

4

Start / End Page

e0120269

Related Subject Headings

  • Rabbits
  • Photoacoustic Techniques
  • Imaging, Three-Dimensional
  • General Science & Technology
  • Esophagus
  • Endosonography
  • Animals
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Yang, J. M., Favazza, C., Yao, J., Chen, R., Zhou, Q., Shung, K. K., & Wang, L. V. (2015). Three-dimensional photoacoustic endoscopic imaging of the rabbit esophagus. PloS One, 10(4), e0120269. https://doi.org/10.1371/journal.pone.0120269
Yang, Joon Mo, Christopher Favazza, Junjie Yao, Ruimin Chen, Qifa Zhou, K Kirk Shung, and Lihong V. Wang. “Three-dimensional photoacoustic endoscopic imaging of the rabbit esophagus.PloS One 10, no. 4 (January 2015): e0120269. https://doi.org/10.1371/journal.pone.0120269.
Yang JM, Favazza C, Yao J, Chen R, Zhou Q, Shung KK, et al. Three-dimensional photoacoustic endoscopic imaging of the rabbit esophagus. PloS one. 2015 Jan;10(4):e0120269.
Yang, Joon Mo, et al. “Three-dimensional photoacoustic endoscopic imaging of the rabbit esophagus.PloS One, vol. 10, no. 4, Jan. 2015, p. e0120269. Epmc, doi:10.1371/journal.pone.0120269.
Yang JM, Favazza C, Yao J, Chen R, Zhou Q, Shung KK, Wang LV. Three-dimensional photoacoustic endoscopic imaging of the rabbit esophagus. PloS one. 2015 Jan;10(4):e0120269.

Published In

PloS one

DOI

EISSN

1932-6203

ISSN

1932-6203

Publication Date

January 2015

Volume

10

Issue

4

Start / End Page

e0120269

Related Subject Headings

  • Rabbits
  • Photoacoustic Techniques
  • Imaging, Three-Dimensional
  • General Science & Technology
  • Esophagus
  • Endosonography
  • Animals