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Calibration-free structured-illumination photoacoustic flowgraphy of transverse flow in scattering media.

Publication ,  Journal Article
Yao, J; Gilson, RC; Maslov, KI; Wang, L; Wang, LV
Published in: Journal of biomedical optics
April 2014

We propose a calibration-free photoacoustic (PA) method for transverse flow measurements. In this method, a pulsed periodically structured (i.e., grating patterned) optical beam is used to illuminate flowing absorptive particles in an optically scattering medium. The PA signal amplitudes measured over consecutive laser pulses carry an imprint of the illumination structure. The modulation frequency of the imprint is proportional to the component of the flow speed projected onto the normal axis of the striped illumination pattern. This method can tolerate high particle density, and is insensitive to the particle size, thus calibration-free. Bovine blood and microsphere phantoms were used to validate the proposed method. Blood flow in a mouse ear was measured in vivo as well.

Duke Scholars

Published In

Journal of biomedical optics

DOI

EISSN

1560-2281

ISSN

1083-3668

Publication Date

April 2014

Volume

19

Issue

4

Start / End Page

046007

Related Subject Headings

  • Photoacoustic Techniques
  • Phantoms, Imaging
  • Particle Size
  • Optics
  • Models, Biological
  • Mice
  • Female
  • Ear
  • Cattle
  • Blood Flow Velocity
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Yao, J., Gilson, R. C., Maslov, K. I., Wang, L., & Wang, L. V. (2014). Calibration-free structured-illumination photoacoustic flowgraphy of transverse flow in scattering media. Journal of Biomedical Optics, 19(4), 046007. https://doi.org/10.1117/1.jbo.19.4.046007
Yao, Junjie, Rebecca C. Gilson, Konstantin I. Maslov, Lidai Wang, and Lihong V. Wang. “Calibration-free structured-illumination photoacoustic flowgraphy of transverse flow in scattering media.Journal of Biomedical Optics 19, no. 4 (April 2014): 046007. https://doi.org/10.1117/1.jbo.19.4.046007.
Yao J, Gilson RC, Maslov KI, Wang L, Wang LV. Calibration-free structured-illumination photoacoustic flowgraphy of transverse flow in scattering media. Journal of biomedical optics. 2014 Apr;19(4):046007.
Yao, Junjie, et al. “Calibration-free structured-illumination photoacoustic flowgraphy of transverse flow in scattering media.Journal of Biomedical Optics, vol. 19, no. 4, Apr. 2014, p. 046007. Epmc, doi:10.1117/1.jbo.19.4.046007.
Yao J, Gilson RC, Maslov KI, Wang L, Wang LV. Calibration-free structured-illumination photoacoustic flowgraphy of transverse flow in scattering media. Journal of biomedical optics. 2014 Apr;19(4):046007.

Published In

Journal of biomedical optics

DOI

EISSN

1560-2281

ISSN

1083-3668

Publication Date

April 2014

Volume

19

Issue

4

Start / End Page

046007

Related Subject Headings

  • Photoacoustic Techniques
  • Phantoms, Imaging
  • Particle Size
  • Optics
  • Models, Biological
  • Mice
  • Female
  • Ear
  • Cattle
  • Blood Flow Velocity