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Photoacoustic microscopy with 7.6-μm axial resolution

Publication ,  Conference
Zhang, C; Maslov, K; Yao, J; Wang, LV
Published in: Progress in Biomedical Optics and Imaging - Proceedings of SPIE
March 4, 2013

The axial resolution of photoacoustic microscopy (PAM) is much lower than its lateral resolution, which resolves down to the submicron level. Here we achieved so far the highest axial resolution of 7.6 μm by using a commercial 125 MHz ultrasonic transducer for signal detection, followed by the Wiener deconvolution for signal processing. The axial resolution was validated by imaging two layers of red ink in a wedge shape. Melanoma cells were imaged ex vivo with high axial resolution. Compared with a PAM system with a 50 MHz ultrasonic transducer, our high-axial-resolution PAM system resolved the blood vessels in mouse ears in vivo much more clearly in the depth direction. © 2013 Copyright SPIE.

Duke Scholars

Published In

Progress in Biomedical Optics and Imaging - Proceedings of SPIE

DOI

ISSN

1605-7422

Publication Date

March 4, 2013

Volume

8581
 

Citation

APA
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MLA
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Zhang, C., Maslov, K., Yao, J., & Wang, L. V. (2013). Photoacoustic microscopy with 7.6-μm axial resolution. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE (Vol. 8581). https://doi.org/10.1117/12.2003248
Zhang, C., K. Maslov, J. Yao, and L. V. Wang. “Photoacoustic microscopy with 7.6-μm axial resolution.” In Progress in Biomedical Optics and Imaging - Proceedings of SPIE, Vol. 8581, 2013. https://doi.org/10.1117/12.2003248.
Zhang C, Maslov K, Yao J, Wang LV. Photoacoustic microscopy with 7.6-μm axial resolution. In: Progress in Biomedical Optics and Imaging - Proceedings of SPIE. 2013.
Zhang, C., et al. “Photoacoustic microscopy with 7.6-μm axial resolution.” Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 8581, 2013. Scopus, doi:10.1117/12.2003248.
Zhang C, Maslov K, Yao J, Wang LV. Photoacoustic microscopy with 7.6-μm axial resolution. Progress in Biomedical Optics and Imaging - Proceedings of SPIE. 2013.

Published In

Progress in Biomedical Optics and Imaging - Proceedings of SPIE

DOI

ISSN

1605-7422

Publication Date

March 4, 2013

Volume

8581