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Optical coherence tomography of retinal astrocytic hamartoma in 15 cases.

Publication ,  Journal Article
Shields, CL; Benevides, R; Materin, MA; Shields, JA
Published in: Ophthalmology
September 2006

OBJECTIVE: To describe the features of retinal astrocytic hamartoma using optical coherence tomography (OCT). DESIGN: Retrospective, observational, noncomparative case series. PARTICIPANTS: Fifteen consecutive eyes from 14 patients with retinal astrocytic hamartoma. MAIN OUTCOME MEASURES: Optical coherence tomography characteristics of the tumor. RESULTS: The mean patient age at OCT was 33 years, and tuberous sclerosis was present in 3 patients (21%). By ophthalmoscopy, the mean basal diameter of the tumor was 3.6 mm. By OCT, the tumor showed hyperreflectivity at its surface, internal retinal disorganization, and a gradual gently sloping transition from a normal retina into a tumorous retina in all 15 cases (100%). By OCT, the retinal disorganization was limited to the inner retina in 3 (20%), outer retina in 0 (0%), full retina in 5 (33%), and inner retina with no view of deeper layers due to shadowing in 7 (47%). On OCT, there was mild retinal traction on the surface of the tumor in 4 (27%), discrete internal moth-eaten optically empty spaces representing intralesional calcification or intratumoral cavities in 10 (67%), and optical shadowing posterior to the tumor in 14 (93%). Other retinal findings on OCT included shallow elevation of the adjacent retina in 2 (13%), adjacent retinal edema in 4 (27%), and macular edema in 3 (20%). CONCLUSIONS: Retinal astrocytic hamartoma shows characteristic features on OCT, including a gradual transition from a normal retina into an optically hyperreflective mass with retinal disorganization, characteristic moth-eaten spaces, and posterior shadowing.

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Published In

Ophthalmology

DOI

EISSN

1549-4713

Publication Date

September 2006

Volume

113

Issue

9

Start / End Page

1553 / 1557

Location

United States

Related Subject Headings

  • Tuberous Sclerosis
  • Tomography, Optical Coherence
  • Retinal Diseases
  • Ophthalmoscopy
  • Ophthalmology & Optometry
  • Middle Aged
  • Male
  • Humans
  • Hamartoma
  • Fluorescein Angiography
 

Citation

APA
Chicago
ICMJE
MLA
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Shields, C. L., Benevides, R., Materin, M. A., & Shields, J. A. (2006). Optical coherence tomography of retinal astrocytic hamartoma in 15 cases. Ophthalmology, 113(9), 1553–1557. https://doi.org/10.1016/j.ophtha.2006.03.032
Shields, Carol L., Raquel Benevides, Miguel A. Materin, and Jerry A. Shields. “Optical coherence tomography of retinal astrocytic hamartoma in 15 cases.Ophthalmology 113, no. 9 (September 2006): 1553–57. https://doi.org/10.1016/j.ophtha.2006.03.032.
Shields CL, Benevides R, Materin MA, Shields JA. Optical coherence tomography of retinal astrocytic hamartoma in 15 cases. Ophthalmology. 2006 Sep;113(9):1553–7.
Shields, Carol L., et al. “Optical coherence tomography of retinal astrocytic hamartoma in 15 cases.Ophthalmology, vol. 113, no. 9, Sept. 2006, pp. 1553–57. Pubmed, doi:10.1016/j.ophtha.2006.03.032.
Shields CL, Benevides R, Materin MA, Shields JA. Optical coherence tomography of retinal astrocytic hamartoma in 15 cases. Ophthalmology. 2006 Sep;113(9):1553–1557.
Journal cover image

Published In

Ophthalmology

DOI

EISSN

1549-4713

Publication Date

September 2006

Volume

113

Issue

9

Start / End Page

1553 / 1557

Location

United States

Related Subject Headings

  • Tuberous Sclerosis
  • Tomography, Optical Coherence
  • Retinal Diseases
  • Ophthalmoscopy
  • Ophthalmology & Optometry
  • Middle Aged
  • Male
  • Humans
  • Hamartoma
  • Fluorescein Angiography