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Predictors and Associations With Outcomes of Length of Hospital Stay in Patients With Acute Heart Failure: Results From VERITAS.

Publication ,  Journal Article
Cotter, G; Davison, BA; Milo, O; Bourge, RC; Cleland, JGF; Jondeau, G; Krum, H; O'Connor, CM; Metra, M; Parker, JD; Torre-Amione, G; Kobrin, I ...
Published in: J Card Fail
October 2016

BACKGROUND: The length of hospital stay (LOS) is important in patients admitted for acute heart failure (AHF) because it prolongs an unpleasant experience for the patients and adds substantially to health care costs. METHODS AND RESULTS: We examined the association between LOS and baseline characteristics, 10-day post-discharge HF readmission, and 90-day post-discharge mortality in 1347 patients with AHF enrolled in the VERITAS program. Longer LOS was associated with greater HF severity and disease burden at baseline; however, most of the variability of LOS could not be explained by these factors. LOS was associated with a higher HF risk of both HF readmission (odds ratio for 1-day increase: 1.08; 95% confidence interval [CI] 1.01-1.16; P = .019) and 90-day mortality (hazard ratio for 1-day increase: 1.05; 95% CI 1.02-1.07; P < .001), although these associations are partially explained by concurrent end-organ damage and worsening heart failure during the first days of admission. CONCLUSIONS: In patients who have been admitted for AHF, longer length of hospital stay is associated with a higher rate of short-term mortality. CLINICAL TRIAL REGISTRATION: VERITAS-1 and -2: Clinicaltrials.gov identifiers NCT00525707 and NCT00524433.

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Published In

J Card Fail

DOI

EISSN

1532-8414

Publication Date

October 2016

Volume

22

Issue

10

Start / End Page

815 / 822

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Time Factors
  • Tetrazoles
  • Survival Analysis
  • Pyridines
  • Proportional Hazards Models
  • Prognosis
  • Patient Readmission
  • Patient Discharge
  • Multivariate Analysis
 

Citation

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Cotter, G., Davison, B. A., Milo, O., Bourge, R. C., Cleland, J. G. F., Jondeau, G., … VERITAS Investigators, . (2016). Predictors and Associations With Outcomes of Length of Hospital Stay in Patients With Acute Heart Failure: Results From VERITAS. J Card Fail, 22(10), 815–822. https://doi.org/10.1016/j.cardfail.2015.12.017
Cotter, Gad, Beth A. Davison, Olga Milo, Robert C. Bourge, John G. F. Cleland, Guillaume Jondeau, Henry Krum, et al. “Predictors and Associations With Outcomes of Length of Hospital Stay in Patients With Acute Heart Failure: Results From VERITAS.J Card Fail 22, no. 10 (October 2016): 815–22. https://doi.org/10.1016/j.cardfail.2015.12.017.
Cotter G, Davison BA, Milo O, Bourge RC, Cleland JGF, Jondeau G, et al. Predictors and Associations With Outcomes of Length of Hospital Stay in Patients With Acute Heart Failure: Results From VERITAS. J Card Fail. 2016 Oct;22(10):815–22.
Cotter, Gad, et al. “Predictors and Associations With Outcomes of Length of Hospital Stay in Patients With Acute Heart Failure: Results From VERITAS.J Card Fail, vol. 22, no. 10, Oct. 2016, pp. 815–22. Pubmed, doi:10.1016/j.cardfail.2015.12.017.
Cotter G, Davison BA, Milo O, Bourge RC, Cleland JGF, Jondeau G, Krum H, O’Connor CM, Metra M, Parker JD, Torre-Amione G, van Veldhuisen DJ, Kobrin I, Rainisio M, Senger S, Edwards C, McMurray JJV, Teerlink JR, VERITAS Investigators. Predictors and Associations With Outcomes of Length of Hospital Stay in Patients With Acute Heart Failure: Results From VERITAS. J Card Fail. 2016 Oct;22(10):815–822.
Journal cover image

Published In

J Card Fail

DOI

EISSN

1532-8414

Publication Date

October 2016

Volume

22

Issue

10

Start / End Page

815 / 822

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Time Factors
  • Tetrazoles
  • Survival Analysis
  • Pyridines
  • Proportional Hazards Models
  • Prognosis
  • Patient Readmission
  • Patient Discharge
  • Multivariate Analysis