Congenital platelet disorder and type I von Willebrand disease presenting as prolonged bleeding after cleft lip and palate repair.
Publication
, Journal Article
Pang, J; Zelken, J; Dorafshar, AH; Strouse, JJ; Redett, R
Published in: Cleft Palate Craniofac J
November 2014
Cleft lip and palate can be associated with coagulopathy. Here, we report the first known case of congenital platelet disorder and von Willebrand disease presenting as prolonged bleeding after cleft lip and palate repair. After identifying the underlying pathology, platelet infusions and aminocaproic acid were given to decrease bleeding from a second surgical procedure. Whole exome sequencing identified a von Willebrand factor gene mutation, an adenine to guanine substitution at the c.475A location. A high index of suspicion should be had for coagulopathy in patients with syndromic cleft lip and palate.
Duke Scholars
Altmetric Attention Stats
Dimensions Citation Stats
Published In
Cleft Palate Craniofac J
DOI
EISSN
1545-1569
Publication Date
November 2014
Volume
51
Issue
6
Start / End Page
740 / 742
Location
United States
Related Subject Headings
- von Willebrand Diseases
- Postoperative Complications
- Male
- Infant
- Humans
- Hemorrhage
- Diagnosis, Differential
- Dentistry
- Cleft Palate
- Cleft Lip
Citation
APA
Chicago
ICMJE
MLA
NLM
Pang, J., Zelken, J., Dorafshar, A. H., Strouse, J. J., & Redett, R. (2014). Congenital platelet disorder and type I von Willebrand disease presenting as prolonged bleeding after cleft lip and palate repair. Cleft Palate Craniofac J, 51(6), 740–742. https://doi.org/10.1597/13-186
Pang, John, Jonathan Zelken, Amir H. Dorafshar, John J. Strouse, and Richard Redett. “Congenital platelet disorder and type I von Willebrand disease presenting as prolonged bleeding after cleft lip and palate repair.” Cleft Palate Craniofac J 51, no. 6 (November 2014): 740–42. https://doi.org/10.1597/13-186.
Pang J, Zelken J, Dorafshar AH, Strouse JJ, Redett R. Congenital platelet disorder and type I von Willebrand disease presenting as prolonged bleeding after cleft lip and palate repair. Cleft Palate Craniofac J. 2014 Nov;51(6):740–2.
Pang, John, et al. “Congenital platelet disorder and type I von Willebrand disease presenting as prolonged bleeding after cleft lip and palate repair.” Cleft Palate Craniofac J, vol. 51, no. 6, Nov. 2014, pp. 740–42. Pubmed, doi:10.1597/13-186.
Pang J, Zelken J, Dorafshar AH, Strouse JJ, Redett R. Congenital platelet disorder and type I von Willebrand disease presenting as prolonged bleeding after cleft lip and palate repair. Cleft Palate Craniofac J. 2014 Nov;51(6):740–742.
Published In
Cleft Palate Craniofac J
DOI
EISSN
1545-1569
Publication Date
November 2014
Volume
51
Issue
6
Start / End Page
740 / 742
Location
United States
Related Subject Headings
- von Willebrand Diseases
- Postoperative Complications
- Male
- Infant
- Humans
- Hemorrhage
- Diagnosis, Differential
- Dentistry
- Cleft Palate
- Cleft Lip